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Parasitological diseases

Section edited by Honorine Ward & Laith Yakob 

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of parasitological diseases in humans, as well as related studies on molecular and cellular biology, pathophysiology, and epidemiology.

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  1. Previous studies reported contradicting findings about the association between intestinal parasitosis and maternal anemia. In this study we aimed to determine the prevalence of intestinal parasitic infection a...

    Authors: Amelo Bolka and Samson Gebremedhin

    Citation: BMC Infectious Diseases 2019 19:483

    Content type: Research article

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  2. Some reports are available on the prevalence of opportunistic parasitoses among hemodialysis (HD) patients, yet there is a paucity of data on the association of CD4+ T-cell counts with such infections. Therefo...

    Authors: Amany I. Shehata, Faika Hassanein and Rashad Abdul-Ghani

    Citation: BMC Infectious Diseases 2019 19:480

    Content type: Research article

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  3. Onchocerciasis is caused by a nematode worm Onchocerca volvulus, which is transmitted in Sudan by black fly vectors of the Simulium damnosum sensu lato species complex. In Sudan, the disease is found in four foci...

    Authors: Isam M. A. Zarroug, Arwa Elaagip, Suhaib G. Gumaa, Altayeb K. Ali, Ayman Ahmed, Hanaa A. M. Siam, Deena M. Abdelgadir, Olabanji A. Surakat, Olatunwa J. Olamiju, Daniel A. Boakye, Nabil Aziz and Kamal Hashim

    Citation: BMC Infectious Diseases 2019 19:477

    Content type: Research article

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  4. Visceral Leishmaniasis (VL) is caused by a protozoan parasite Leishmania donovani that is transmitted to humans by an infected female sandfly, Phlebotomus argentipes. VL is common in the Indian sub-continent incl...

    Authors: Mitesh Shrestha, Medha Khatri-Chhetri, Ram Chandra Poudel, Jyoti Maharjan, Shyam Prakash Dumre, Krishna Das Manandhar, Basu Dev Pandey, Sher Bahadur Pun and Kishor Pandey

    Citation: BMC Infectious Diseases 2019 19:444

    Content type: Research article

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  5. Lymphatic Filariasis (LF) is a vector-borne neglected tropical disease caused by the filarial nematode parasites that can lead to the disfiguring swelling of the limbs (lymphedema or elephantiasis for late sta...

    Authors: Alexander Kwarteng, Yarhands Dissou Arthur, John Kanyiri Yamba, Augustina A. Sylverken, Priscilla Kini, Samuel Terkper Ahuno and Ellis Owusu-Dabo

    Citation: BMC Infectious Diseases 2019 19:442

    Content type: Research article

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  6. Onchocerciasis is a neglected tropical disease which is still of immense major public health concern in several areas of Africa and the Americas. The disease manifests either as ocular or as dermal onchocercia...

    Authors: Kenneth Bentum Otabil, Samuel Fosu Gyasi, Esi Awuah, Daniels Obeng-Ofori, Robert Junior Atta-Nyarko, Dominic Andoh, Beatrice Conduah, Lawrence Agbenyikey, Philip Aseidu, Comfort Blessing Ankrah, Abdul Razak Nuhu and H. D. F. H. Schallig

    Citation: BMC Infectious Diseases 2019 19:431

    Content type: Research article

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  7. Malaria continues to be a public health problem and important cause of morbidity and mortality in Ethiopia. Due to continuous interventions to combat malaria in endemic regions, a decline in malaria related de...

    Authors: Teha Shumbej, Abdulewhab Jemal, Abdulsemed Worku, Fitsum Bekele and Habtamu Weldesenbet

    Citation: BMC Infectious Diseases 2019 19:413

    Content type: Research article

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  8. Consumption of unwashed, raw or unhygienically prepared fruits and vegetables act as potential source for the spread of various parasitic diseases. Moreover, the level of contamination and species of contamina...

    Authors: Getaneh Alemu, Mohammedaman Mama, Direslgne Misker and Desta Haftu

    Citation: BMC Infectious Diseases 2019 19:410

    Content type: Research article

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  9. In co-endemic areas, rate of intestinal parasites and tuberculosis (TB) co-infection thought to be high. However, there are limited studies on the epidemiology of this co-infection in Ethiopia. Therefore, the ...

    Authors: Ayinalem Alemu, Abebaw Kebede, Biniyam Dagne, Misikir Amare, Getu Diriba, Bazezew Yenew, Ephrem Tesfaye, Mengistu Tadesse, Waganeh Sinshaw, Dawit Challa and Kassu Desta

    Citation: BMC Infectious Diseases 2019 19:407

    Content type: Research article

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  10. In Ethiopia, like other developing countries, intestinal parasitic infections are the major public health problems affecting millions annually. Overcrowding and poor living conditions are the major risk factor...

    Authors: Fitsum Mardu, Mekonnen Yohannes and Desalegn Tadesse

    Citation: BMC Infectious Diseases 2019 19:406

    Content type: Research article

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  11. Quinine (QN) remains an effective drug for malaria treatment. However, quinine resistance (QNR) in Plasmodium falciparum has been reported in many malaria-endemic regions particularly in African countries. Geneti...

    Authors: Kai Wu, Yi Yao, Fang Chen, Mingxing Xu, Guangquan Lu, Tingting Jiang, Ziyu Liu, Weixing Du, Fang Li, Rugui Li, Huabing Tan and Jian Li

    Citation: BMC Infectious Diseases 2019 19:354

    Content type: Research article

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  12. Intestinal parasitic infections (IPIs) have been major public health problems in low income countries primarily affecting school children. Previous studies in Ethiopia have shown high burden of intestinal para...

    Authors: Baye Sitotaw, Haileyesus Mekuriaw and Destaw Damtie

    Citation: BMC Infectious Diseases 2019 19:341

    Content type: Research article

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  13. Lymphatic filariasis (LF) is a mosquito-borne parasitic disease and a major cause of disability worldwide. To effectively plan morbidity management programmes, it is important to estimate disease burden and ev...

    Authors: Obiora A. Eneanya, Tini Garske and Christl A. Donnelly

    Citation: BMC Infectious Diseases 2019 19:332

    Content type: Research article

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  14. In Vietnam, few studies have determined the epidemiological status of toxoplasmosis in pregnant women and no routine prenatal screening is in place. This study was conducted to evaluate the seroprevalence of t...

    Authors: G. Suzanne A. Smit, Binh Thi Lam Vu, Dung Trung Do, Quan Ha Do, Huy Quang Pham, Niko Speybroeck, Brecht Devleesschauwer, Elizaveta Padalko, Ellen Roets and Pierre Dorny

    Citation: BMC Infectious Diseases 2019 19:329

    Content type: Research article

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  15. Visceral leishmaniasis is a vector-borne parasitic disease caused by protozoa belonging to the genus Leishmania. The clinical presentation of visceral leishmaniasis strictly depends on the host immunocompetency, ...

    Authors: Claudia Colomba, Laura Saporito, Paola Di Carlo, Manlio Tolomeo, Adriana Cervo, Alberto Firenze, Marcello Trizzino and Antonio Cascio

    Citation: BMC Infectious Diseases 2019 19:328

    Content type: Case report

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  16. Toxoplasma gondii infection is a great health concern to pregnant women and the developing fetus. The aim of this study was to determine the seroprevalence of T. gondii and its associated factors in Adwa district...

    Authors: Mebrahtu Teweldemedhin, Amaha Gebremichael, Gebretsadkan Geberkirstos, Haftom Hadush, Tuam Gebrewahid, Solomon Weldegebreal Asgedom, Berihu Gidey, Negasi Asres and Hailay Gebreyesus

    Citation: BMC Infectious Diseases 2019 19:327

    Content type: Research article

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  17. Cutaneous leishmaniasis (CL) is an important public health problem in Brazil and in several tropical regions of the world. In the Americas, Brazil is the country with the highest number of registered cases. In...

    Authors: Diogo Tavares Cardoso, Dayane Costa de Souza, Vanessa Normandio de Castro, Stefan Michael Geiger and David Soeiro Barbosa

    Citation: BMC Infectious Diseases 2019 19:318

    Content type: Research article

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  18. The prevalence of Plasmodium falciparum and Intestinal Parasitic Infections (IPIs) - with the corresponding pathogenesis among children remain uncertain. This study aimed at determining the prevalence and the out...

    Authors: Paul Oboth, Yahaya Gavamukulya and Banson John Barugahare

    Citation: BMC Infectious Diseases 2019 19:295

    Content type: Research article

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  19. Intestinal parasites still pose major public health problems in developing countries like Ethiopia. Local epidemiological data is indispensable in order to design and monitor prevention and control strategies....

    Authors: Getaneh Alemu, Ashenafi Abossie and Zerihun Yohannes

    Citation: BMC Infectious Diseases 2019 19:270

    Content type: Research article

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  20. Soil-transmitted helminthiasis affects almost 2 billion people worldwide in tropical climates. Preventive chemotherapy, using the benzimidazoles (albendazole and mebendazole) is the current main recommended co...

    Authors: Chandni Patel, Eveline Hürlimann, Ladina Keller, Jan Hattendorf, Somphou Sayasone, Said M Ali, Shaali M Ame, Jean T Coulibaly and Jennifer Keiser

    Citation: BMC Infectious Diseases 2019 19:262

    Content type: Study protocol

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  21. Environmental, social, geographical, and other factors could affect the distribution of intestinal parasites. Parasitic infections would impose on health and social problems like mal-absorption, diarrhea, impa...

    Authors: Habtamu Sewunet Mekonnen and Daniale Tekelia Ekubagewargies

    Citation: BMC Infectious Diseases 2019 19:256

    Content type: Research article

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  22. Chronic Chagas Disease (CD) diagnosis is based on serological methods employing crude, semipurified or recombinant antigens, which may result in low sensitivity or cross-reactivity. To reduce these restriction...

    Authors: Eva Dopico, Rodrigo Pimenta Del-Rei, Bertha Espinoza, Itziar Ubillos, Nilson Ivo Tonin Zanchin, Elena Sulleiro, Zaira Moure, Paola Alejandra Fiorani Celedon, Wayner Vieira Souza, Edimilson Domingos da Silva, Yara Miranda Gomes and Fred Luciano Neves Santos

    Citation: BMC Infectious Diseases 2019 19:251

    Content type: Research article

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  23. The WHO recommends single low-dose primaquine (SLDPQ, 0.25 mg/kg body weight) in falciparum-infected patients to block malaria transmission and contribute to eliminating multidrug resistant Plasmodium falciparum ...

    Authors: Lek Dysoley, Saorin Kim, Sergio Lopes, Nimol Khim, Steven Bjorges, Samphornarann Top, Chea Huch, Huy Rekol, Nelli Westercamp, Mark M. Fukuda, Jimee Hwang, Arantxa Roca-Feltrer, Mavuto Mukaka, Didier Menard and Walter R. Taylor

    Citation: BMC Infectious Diseases 2019 19:250

    Content type: Research article

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  24. Malaria and leishmaniasis are the two largest parasitic killers in the world. Due togeographical overlap of these diseases, malaria-visceral leishmaniasis co-infections occur in large populations and exist in ...

    Authors: Yibeltal Aschale, Animen Ayehu, Ligabaw Worku, Habtie Tesfa, Meseret Birhanie and Wossenseged Lemma

    Citation: BMC Infectious Diseases 2019 19:239

    Content type: Research article

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  25. Schistosomiasis is a devastating parasitic disease. The mainstay of schistosomiasis control is by praziquantel treatment. The study aimed to determine benefits of annual chemotherapy of schistosomiasis on deve...

    Authors: Tawanda J. Chisango, Bongiwe Ndlovu, Arthur Vengesai, Agness Farai Nhidza, Edson P. Sibanda, Danai Zhou, Francisca Mutapi and Takafira Mduluza

    Citation: BMC Infectious Diseases 2019 19:219

    Content type: Research article

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  26. Accurate diagnosis of Toxoplasma gondii (T. gondii) infection remains elusive and requires a comprehensive assessment through laboratory and clinical investigation. In this study, a diagnostic algorithm based on ...

    Authors: Padmaloseni Thangarajah, Khalid Hajissa, Weng Kin Wong, Muhammad Amiruddin Abdullah, Nabilah Ismail and Zeehaida Mohamed

    Citation: BMC Infectious Diseases 2019 19:202

    Content type: Research article

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  27. Infestations with scabies mites are a global burden affecting individuals of all ages, classes and ethnicities. As poor sanitation and overcrowding favor the transmission of this highly contagious disease, epi...

    Authors: Simon M. Mueller, Stefan Gysin, Michael Schweitzer, Simon Schwegler, Peter Haeusermann, Peter Itin, Thomas Bart, Ruth Spieler Denz, Thomas Steffen, Richard Kuehl, Andreas F. Widmer and Oliver Brandt

    Citation: BMC Infectious Diseases 2019 19:200

    Content type: Research article

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  28. Parasitic infections, particularly those caused by protozoa, represent a considerable public health problem in developing countries. Blastocystis, Giardia duodenalis, Cryptosporidium spp. and the Entamoeba comple...

    Authors: Ximena Villamizar, Adriana Higuera, Giovanny Herrera, Luis Reinel Vasquez-A, Lorena Buitron, Lina Maria Muñoz, Fabiola E. Gonzalez-C, Myriam Consuelo Lopez, Julio Cesar Giraldo and Juan David Ramírez

    Citation: BMC Infectious Diseases 2019 19:190

    Content type: Research article

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  29. Taenia solium taeniosis/cysticercosis is a public health and agricultural problem, especially in low-income countries, and has been ranked the top foodborne parasitic hazard globally. In 2012, the World Health Or...

    Authors: Uffe Christian Braae, Sarah Gabriël, Chiara Trevisan, Lian F. Thomas, Pascal Magnussen, Bernadette Abela-Ridder, Helena Ngowi and Maria Vang Johansen

    Citation: BMC Infectious Diseases 2019 19:182

    Content type: Debate

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  30. Prevalence of schistosomiasis is high among children under five years in Uganda. Schistosomiasis control efforts over time have included periodic mass treatments in endemic areas for adults and school going ch...

    Authors: Simon Peter Sebina Kibira, John C. Ssempebwa, Ronald Ssenyonga, Scott Radloff and Fredrick Edward Makumbi

    Citation: BMC Infectious Diseases 2019 19:165

    Content type: Research article

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  31. Loiasis is a vector-borne parasitic disease due to Loa loa and transmitted to humans by tabanids of the genus Chrysops. Loiasis has been historically considered as the second or third most common reason for medic...

    Authors: Aude E. Mogoung-Wafo, Hugues C. Nana-Djeunga, André Domche, Floribert Fossuo-Thotchum, Jean Bopda, Steve Mbickmen-Tchana, Honoré Djomo-Kamga and Joseph Kamgno

    Citation: BMC Infectious Diseases 2019 19:146

    Content type: Research article

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  32. Soil-transmitted helminthic (STH) infections are common in Sub-Saharan Africa. One method used for control of these helminths is mass anti-helminthic administration in populations at risk of STH infections. In...

    Authors: Abdulazeez Imam, Zubaida L. Farouk, Fatimah Hassan-Hanga and Uchechukwu G. Ihesiulor

    Citation: BMC Infectious Diseases 2019 19:121

    Content type: Research article

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  33. Clonorchiasis is the common parasitic infection in the general population of the Republic of Korea, however, taeniasis is scarcely reported recently. Here, we describe a case of co-infection with the cestode T. s...

    Authors: Ju Hyeon Shin, Eun Jeong Won, Jee Seung Jung, Kyung-Hwa Park, Kwang Il Nam, Soo Hyun Kim and Jong Hee Shin

    Citation: BMC Infectious Diseases 2019 19:115

    Content type: Case report

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  34. Cutaneous leishmaniasis (CL) caused by Leishmania species, is a geographically extensive disease that infects humans and animals. CL is endemic in half of the 31 provinces of Iran, with 29,201 incidence cases rep...

    Authors: Iraj Mohammadpour, Gholam Reza Hatam, Farhad Handjani, Farzaneh Bozorg-Ghalati, Daniel PourKamal and Mohammad Hossein Motazedian

    Citation: BMC Infectious Diseases 2019 19:98

    Content type: Research article

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  35. Making a definite diagnosis of infectious uveitis is a challenging task because many other infectious, and non-infectious uveitis, may have similar non-specific symptoms and overlapping clinical appearances. C...

    Authors: Alejandra de-la-Torre, Juanita Valdés-Camacho, Clara López de Mesa, Andrés Uauy-Nazal, Juan David Zuluaga, Lina María Ramírez-Páez, Felipe Durán, Elizabeth Torres-Morales, Jessica Triviño, Mateo Murillo, Alba Cristina Peñaranda, Juan Carlos Sepúlveda-Arias and Jorge Enrique Gómez-Marín

    Citation: BMC Infectious Diseases 2019 19:91

    Content type: Research article

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  36. Malaria clinical outcomes vary by erythrocyte characteristics, including ABO blood group, but the effect of ABO blood group on asymptomatic, uncomplicated and placental Plasmodium falciparum (P. falciparum) infec...

    Authors: Abraham Degarege, Merhawi T. Gebrezgi, Consuelo M. Beck-Sague, Mats Wahlgren, Luiz Carlos de Mattos and Purnima Madhivanan

    Citation: BMC Infectious Diseases 2019 19:86

    Content type: Research article

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  37. Human schistosomiases are acute and chronic infectious diseases of poverty. Currently, epidemiological data of urinary schistosomiasis (US) in school-age children (SAC) and adults are often reported together m...

    Authors: Tolulope Ebenezer Atalabi and Taiwo Oluwakemi Adubi

    Citation: BMC Infectious Diseases 2019 19:73

    Content type: Research article

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    The Retraction Note to this article has been published in BMC Infectious Diseases 2020 20:93

  38. Visceral leishmaniasis (VL) is becoming endemic in São Paulo state, in the southeastern region of Brazil. Unusual manifestations with non-specific signs and symptoms may make diagnosis difficult and delay trea...

    Authors: Luiz Euribel Prestes-Carneiro, Patricia Rodrigues Naufal Spir, Mateus Fontanesi, Karen Gabriella Pereira Garcia, Francisco Assis da Silva, Edilson Ferreira Flores and Dewton de Moraes Vasconcelos

    Citation: BMC Infectious Diseases 2019 19:70

    Content type: Case report

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  39. Cystic echinococcosis (CE) is a worldwide zoonosis and the liver is the most commonly affected organ. Clinical manifestations range from completely asymptomatic cysts to a potential lethal cyst rupture and ana...

    Authors: Flaminia Coluzzi, Roberto Luca Meniconi, Damiano Caruso, Flaminia Rivosecchi, Linda Petrone, Delia Goletti and Giuseppe Maria Ettorre

    Citation: BMC Infectious Diseases 2019 19:37

    Content type: Case report

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  40. Hepatic clonorchiasis is one of the most prevalent food-borne parasitic diseases worldwide. Clonorchis sinensis, the pathogen, is the major parasitic trigger contributing to cholangitis, cholelithiasis, and even ...

    Authors: Xialei Liu, Genglong Zhu, Chaonong Cai, Zhiyue Lv and Jian Li

    Citation: BMC Infectious Diseases 2019 19:33

    Content type: Case report

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  41. Cutaneous leishmaniasis (CL) is a serious health problem in Suriname. To expand the diagnostic options, two newly developed diagnostic tests, i.e. the rapid diagnostic test CL Detect™ Rapid Test (CL Detect) an...

    Authors: Henk D. F. H. Schallig, Ricardo V. P. Hu, Alida D. Kent, Merlin van Loenen, Sandra Menting, Albert Picado, Zippora Oosterling and Israel Cruz

    Citation: BMC Infectious Diseases 2019 19:25

    Content type: Research article

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  42. Visceral leishmaniasis (VL) is a neglected tropical disease of public health relevance in Brazil. To prioritize disease control measures, the Secretaria de Vigilância em Saúde of Brazil’s Ministry of Health (S...

    Authors: Gustavo Machado, Julio Alvarez, Haakon Christopher Bakka, Andres Perez, Lucas Edel Donato, Francisco Edilson de Ferreira Lima Júnior, Renato Vieira Alves and Victor Javier Del Rio Vilas

    Citation: BMC Infectious Diseases 2019 19:2

    Content type: Research article

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  43. We report on a 21-year-old patient with a giant symptomatic hydatid cyst of the interventricular septum, to whom a staged management approach was employed. Induction medical therapy led to a reduction in the s...

    Authors: Jadranka Separovic Hanzevacki, Hrvoje Gasparovic, Vlatka Reskovic Luksic, Zvonimir Ostojic and Bojan Biocina

    Citation: BMC Infectious Diseases 2018 18:694

    Content type: Case report

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  44. The immune response during P. falciparum infection is a two-edged sword, involving dysregulation of the inflammatory responses with several types of immune cells participating. Here we examined T-cell, monocyte/m...

    Authors: Kari Otterdal, Aase Berg, Annika E. Michelsen, Sam Patel, Marit G. Tellevik, Christel G. Haanshuus, Børre Fevang, Pål Aukrust, Nina Langeland and Thor Ueland

    Citation: BMC Infectious Diseases 2018 18:670

    Content type: Research article

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  45. To combat emerging drug resistance in the Greater Mekong Sub-region (GMS) the World Health Organization and GMS countries have committed to eliminating malaria in the region by 2030. The overall approach inclu...

    Authors: Win Han Oo, Julia C. Cutts, Paul A. Agius, Kyaw Zayar Aung, Poe Poe Aung, Aung Thi, Nyi Nyi Zaw, Htin Kyaw Thu, Wai Yan Min Htay, Ricardo Ataide, Katherine O’Flaherty, Ai Pao Yawn, Aung Paing Soe, James G. Beeson, Brendan Crabb, Naanki Pasricha…

    Citation: BMC Infectious Diseases 2018 18:663

    Content type: Study protocol

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  46. Large scale administration of the anthelminthic drug praziquantel (PZQ) to at-risk populations is the cornerstone of schistosomiasis control, although persisting high prevalence of infections in some areas and...

    Authors: P. T. Hoekstra, M. Casacuberta Partal, A. S. Amoah, L. van Lieshout, P. L. A. M. Corstjens, S. Tsonaka, R. K. Assaré, K. D. Silué, A. Meité, E. K. N’Goran, Y. K. N’Gbesso, M. Roestenberg, S. Knopp, J. Utzinger, J. T. Coulibaly and G. J. van Dam

    Citation: BMC Infectious Diseases 2018 18:662

    Content type: Study protocol

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  47. About 80% of all reported sickle cell disease (SCD) cases in children anually are recorded in Africa. Although malaria is considered a major cause of death in SCD children, there is limited data on the safety ...

    Authors: Augustina Frimpong, Laty Gaye Thiam, Benjamin Arko-Boham, Ewurama Dedea Ampadu Owusu and George O. Adjei

    Citation: BMC Infectious Diseases 2018 18:650

    Content type: Research article

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  48. Malaria prevalence in Cameroon is a major public health problem both at the regional and urban-rural geographic scale. In 2016, an estimated 1.6 million confirmed cases, and 18,738 cases were reported in healt...

    Authors: Marlvin Anemey Tewara, Prisca Ngetemalah Mbah-Fongkimeh, Alimu Dayimu, Fengling Kang and Fuzhong Xue

    Citation: BMC Infectious Diseases 2018 18:636

    Content type: Research article

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  49. Leishmaniasis is a neglected and poorly reported parasitic infection transmitted by sand flies in tropical and subtropical regions. Knowledge about leishmaniasis has become important in non-endemic countries d...

    Authors: Hedvig Glans, Leif Dotevall, Sara Karlsson Söbirk, Anna Färnert and Maria Bradley

    Citation: BMC Infectious Diseases 2018 18:632

    Content type: Research article

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  50. Previous studies have suggested that Toxoplasma gondii (T. gondii) infection might be associated with fatty liver disease. However, the relationship between non-alcoholic fatty liver disease (NAFLD) and T. gondii

    Authors: Jiaofeng Huang, Haoyang Zhang, Shiying Liu, Mingfang Wang, Bo Wan, Bharat Velani, Yueyong Zhu and Su Lin

    Citation: BMC Infectious Diseases 2018 18:629

    Content type: Research article

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