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Parasitological diseases

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of parasitological diseases in humans, as well as related studies on molecular and cellular biology, pathophysiology, and epidemiology.

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  1. Mounting evidence suggested a complex correlation between host lipid metabolism and Toxoplasma gondii (T. gondii) infection. However, the inherent association between T. gondii infection and host lipid state rema...

    Authors: Fei Xu, Xiwan Lu, Ruitang Cheng, Yuwei Zhu, Sunhan Miao, Qinyi Huang, Yongliang Xu, Liying Qiu and Yonghua Zhou

    Citation: BMC Infectious Diseases 2020 20:415

    Content type: Research article

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  2. Successful control programs have impeded local malaria transmission in almost all Gulf Cooperation Council (GCC) countries: Qatar, Bahrain, Kuwait, Oman, the United Arab Emirates (UAE) and Saudi Arabia. Nevert...

    Authors: Abir Al-Rumhi, Zainab Al-Hashami, Salama Al-Hamidhi, Amal Gadalla, Raeece Naeem, Lisa Ranford-Cartwright, Arnab Pain, Ali A. Sultan and Hamza A. Babiker

    Citation: BMC Infectious Diseases 2020 20:413

    Content type: Research article

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  3. Visceral leishmaniasis is an important but neglected disease that is spreading and is highly lethal when left untreated. This study sought to measure the Leishmania infantum seroprevalence in dogs, the coverage o...

    Authors: Patricia Marques Moralejo Bermudi, Danielle Nunes Carneiro Castro Costa, Caris Maroni Nunes, Jose Eduardo Tolezano, Roberto Mitsuyoshi Hiramoto, Lilian Aparecida Colebrusco Rodas, Rafael Silva Cipriano, Marta Blangiardo and Francisco Chiaravalloti-Neto

    Citation: BMC Infectious Diseases 2020 20:401

    Content type: Research article

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  4. Scabies is an infectious disease that affects the skin caused by the mite Sarcoptes scabiei and it transmitted through close personal contact. Even though it is easily treatable disease, its prevalence is high an...

    Authors: Abebaw Gedef Azene, Abiba Mihret Aragaw and Gizachew Tadesse Wassie

    Citation: BMC Infectious Diseases 2020 20:380

    Content type: Research article

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  5. Intestinal parasitic infections (IPIs) and anaemia are major health problems. This study assessed the prevalence of intestinal parasitic infections, anaemia and associated factors among pre-school children in ...

    Authors: Araya Gebreyesus Wasihun, Mekonen Teferi, Letemichal Negash, Javier Marugán, Dejen Yemane, Kevin G. McGuigan, Ronan M. Conroy, Haftu Temesgen Abebe and Tsehaye Asmelash Dejene

    Citation: BMC Infectious Diseases 2020 20:379

    Content type: Research article

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  6. Despite the existence of a population-based control program using single dose albendazole or mebendazole as a preventive chemotherapy, hookworm transmission remains high. It causes a negative impact on the gro...

    Authors: Tegegne Eshetu, Mulugeta Aemero and Ayalew Jejaw Zeleke

    Citation: BMC Infectious Diseases 2020 20:376

    Content type: Research article

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  7. Plasmodium vivax rarely develops severe complications when compared to severe falciparum malaria. However, severe vivax malaria also needs urgent, intensive care and treatment as severe falciparum malaria. This s...

    Authors: Manas Kotepui, Kwuntida Uthaisar Kotepui, Giovanni De Jesus Milanez and Frederick Ramirez Masangkay

    Citation: BMC Infectious Diseases 2020 20:363

    Content type: Research article

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  8. Microscopic examination of peripheral blood smear produces reliable results both about the malaria infection status and level of parasitemia. However, test results are affected by skill of the laboratory perso...

    Authors: Banchamlak Tegegne, Kefale Ejigu, Getaneh Alemu, Yeshimebet Fetene, Kindye Endaylalu and Mulatu Melese

    Citation: BMC Infectious Diseases 2020 20:355

    Content type: Research article

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  9. Pediatric diarrhea caused by a range of pathogens, including intestinal parasites, is one of main causes of death among children under 5 years of age. The distribution of these parasitic infections overlaps in...

    Authors: Sandrine Lydie Oyegue-Liabagui, Nal Kennedy Ndjangangoye, Lady Charlene Kouna, Gwladys Mirlande Lekolo, Franck Mounioko, Sylvie Kwedi Nolna and Jean Bernard Lekana-Douki

    Citation: BMC Infectious Diseases 2020 20:350

    Content type: Research article

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  10. Besides the considerable role of blackflies to the transmission of many disease agents, these flies considered as annoying biting pests of wildlife, livestock, poultry, and humans. There are few literature rep...

    Authors: Farbod Tabatabaei, Sahar Azarmi, Mohammad Javad Abbaszadeh Afshar, Hamed Yarizadeh and Sina Mohtasebi

    Citation: BMC Infectious Diseases 2020 20:348

    Content type: Case report

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  11. Enterobius vermicularis is an intestinal helminthic parasite that causes a gastrointestinal infection called enterobiasis. Children are more susceptible to infection than adults. The current study aimed to explor...

    Authors: Ahmed Akil Khudhair Al-Daoody and Eman Najdy Haydar Al-Bazzaz

    Citation: BMC Infectious Diseases 2020 20:336

    Content type: Research article

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  12. Malaria is a life threating vector borne disease caused by different Plasmodium parasites. Metema and Armachiho are two of the top five malaria endemic areas among the districts of Amhara region in Ethiopia. Tran...

    Authors: Yibeltal Aschale, Animen Ayehu, Ligabaw Worku, Ayenew Addisu, Ayalew Jejaw Zeleke, Abebe Genetu Bayih and Wossenseged Lemma

    Citation: BMC Infectious Diseases 2020 20:333

    Content type: Research article

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  13. Praziquantel (PZQ) is the standard treatment for Schistosomiasis in sub-Saharan Africa. However, there is evidence suggesting praziquantel treatment failure in Schistosome infections with associated potential ...

    Authors: Samuel Nkansah Darko, Henry Hanson, Sampson Twumasi-Ankrah, Sandra Baffour-Awuah, Priscilla Adjei-Kusi, Denis Yar and Ellis Owusu-Dabo

    Citation: BMC Infectious Diseases 2020 20:323

    Content type: Research article

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  14. Scrub typhus can present with atypical signs and symptoms such as those of acute kidney injury, gastroenteritis, pneumonitis, and acute respiratory distress syndrome. Meningitis, encephalitis, and hepatic dysf...

    Authors: Tulsi Bhattarai, Sujan Chandra Poudel, Nishma Pokharel and Suraj Bhattarai

    Citation: BMC Infectious Diseases 2020 20:322

    Content type: Case report

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  15. Trichomoniasis resulting from Trichomonas vaginalis (T. vaginalis) has been considered as a commonly seen disease with the transmission way of sex. At present, the detection methods of T. vaginalis mainly include...

    Authors: Yuhua Li, Shuai Wang, Haoran Li, Xiaoxiao Song, Hao Zhang, Yujuan Duan, Chengyang Luo, Bingli Wang, Sifan Ji, Qing Xie and Zhenchao Zhang

    Citation: BMC Infectious Diseases 2020 20:319

    Content type: Research article

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  16. Plasmodium vivax is the most widely distributed malaria parasite, and its drug resistance poses unique challenges to malaria elimination. The Greater Mekong Subregion (GMS) is known as the global epicenter of mul...

    Authors: Xiaoxiao Wang, Wei Ruan, Shuisen Zhou, Xinyu Feng, He Yan and Fang Huang

    Citation: BMC Infectious Diseases 2020 20:307

    Content type: Research article

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  17. In Ghana, pre-school-aged children (PSAC) are at risk of intestinal schistosomiasis and are living in need of praziquantel treatment. To better assess the infection burden within this vulnerable demographic gr...

    Authors: Samuel Armoo, Lucas J. Cunningham, Suzy J. Campbell, Frank T. Aboagye, Freda K. Boampong, Buhari A. Hamidu, Mike Y. Osei-Atweneboana, J. Russell Stothard and Emily R. Adams

    Citation: BMC Infectious Diseases 2020 20:301

    Content type: Research article

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  18. The control of lymphatic filariasis (LF) caused by Wuchereria bancrofti in the Central African Region has been hampered by the presence of Loa loa due to severe adverse events that arise in the treatment with ive...

    Authors: Andrew A. Beng, Mathias E. Esum, Kebede Deribe, Abdel J. Njouendou, Patrick W. C. Ndongmo, Raphael A. Abong, Jerome Fru, Fanny F. Fombad, Gordon T. Nchanji, Glory Amambo, Narcisse T. V. Gandjui, Benjamin Biholong, Georges Nko’Ayissi, Patrick Mbia, Julie Akame, Peter I. Enyong…

    Citation: BMC Infectious Diseases 2020 20:284

    Content type: Research article

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  19. Emerging data has suggested that Tregs, Th17, Th1 and Th2 are correlated with early immune mechanisms by controlling Plasmodium infection. Plasmodium infection appeared to impair the antigen presentation and matu...

    Authors: Guang Chen, Ji-wei Du, Qing Nie, Yun-ting Du, Shuang-chun Liu, De-hui Liu, Hui-ming Zhang and Fang-fang Wang

    Citation: BMC Infectious Diseases 2020 20:266

    Content type: Research article

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  20. Echinococcosis is a zoonotic parasitic disease causing serious health problems in both humans and animals in different endemic regions across the world. There are two different forms of human echinococcosis: C...

    Authors: Aisha Khan, Haroon Ahmed, Sami Simsek, Hua Liu, Jianhai Yin, Ying Wang, Yujuan Shen and Jianping Cao

    Citation: BMC Infectious Diseases 2020 20:262

    Content type: Research article

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  21. Cryptosporidium sp. are common intracellular parasites responsible of severe diarrhea in T-cell-immunocompromised patients. We report the first case of a woman who contracted cryptosporidiosis after treatment wit...

    Authors: M. Martinot, A. Abou-Bacar, M. Lamothe, M. Alt Tebacher, M. Mohseni Zadeh, F. Dalle, L. Favennec, D. Costa, J. Brunet and F. Sellal

    Citation: BMC Infectious Diseases 2020 20:257

    Content type: Case report

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  22. The management of disseminated cysticercosis is unclear and largely considered hazardous. The role of albendazole remains controversial in such patients.

    Authors: Sudhakar Pandey, Hardeep Singh Malhotra, Ravindra Kumar Garg, Kiran Preet Malhotra, Neeraj Kumar, Imran Rizvi, Amita Jain, Neera Kohli, Rajesh Verma, Praveen Sharma, Ravi Uniyal and Shweta Pandey

    Citation: BMC Infectious Diseases 2020 20:220

    Content type: Research article

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  23. In the Republic of Congo, hot temperature and seasons distortions observed may impact the development of malaria parasites. We investigate the variation of malaria cases, parasite density and the multiplicity of

    Authors: Pembe Issamou Mayengue, Dezi Kouhounina Batsimba, Roch Fabien Niama, Reyna Ibara Ottia, Alida Malonga-Massanga, Grâce Petula Urielle Fila-Fila, Gabriel Ahombo, Simon Charles Kobawila and Henri Joseph Parra

    Citation: BMC Infectious Diseases 2020 20:190

    Content type: Research article

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  24. In recent times, Plasmodium vivax (P. vivax) has become a serious threat to public health due to its ability to cause severe infection with fatal outcomes. Its unique biology makes it resilient to control measure...

    Authors: Apoorva Venkatesh, Shalini Aggarwal, Swati Kumar, Srushti Rajyaguru, Vipin Kumar, Sheetal Bankar, Jayanthi Shastri, Swati Patankar and Sanjeeva Srivastava

    Citation: BMC Infectious Diseases 2020 20:188

    Content type: Research article

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  25. American tegumentary leishmaniasis (ATL) is a widespread anthropozoonosis caused by protozoa of the genus Leishmania and is considered a serious public health problem. The aim of this study was to provide a descr...

    Authors: Mariana Olímpia Köhler Marra Pinto, Tiago Mendonça de Oliveira, Andreza Nayla de Assis Aguiar, Paulo Eustáquio Marra Pinto, David Soeiro Barbosa, Soraia de Araújo Diniz and Marcos Xavier Silva

    Citation: BMC Infectious Diseases 2020 20:163

    Content type: Research article

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  26. Intestinal infection is still an important public health problem in low-income countries. Food handlers may be infected by a wide range of enteropathogens and have been implicated in the transmission of many i...

    Authors: Birhan Alemnew, Getnet Gedefaw, Gedefaw Diress and Asmamaw Demis Bizuneh

    Citation: BMC Infectious Diseases 2020 20:156

    Content type: Research article

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  27. Chagas disease is caused by the haemoflagellate protozoan Trypanosoma cruzi. Currently, T. cruzi recognizes seven discrete typing units (DTUs): TcI to TcVI and Tcbat. The genetic diversity of T. cruzi is suspecte...

    Authors: Manuel Calvopina, Gabriela Segovia, William Cevallos, Yosselin Vicuña, Jaime A. Costales and Angel Guevara

    Citation: BMC Infectious Diseases 2020 20:143

    Content type: Case report

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  28. Globally, Taenia solium can cause cysticercosis in humans (including neurocysticercosis) and in pigs through ingestion of eggs and taeniasis in humans through ingestion of raw/undercooked pork contaminated with m...

    Authors: Msawenkosi I. Sithole, Johan L. Bekker and Samson Mukaratirwa

    Citation: BMC Infectious Diseases 2020 20:107

    Content type: Research article

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  29. The immune response during falciparum malaria mediates both harmful and protective effects on the host; however the participating molecules have not been fully defined. Interleukin (IL)-27 is a pleiotropic cyt...

    Authors: Kari Otterdal, Aase Berg, Annika E. Michelsen, Sam Patel, Ida Gregersen, Ellen Lund Sagen, Bente Halvorsen, Arne Yndestad, Thor Ueland, Nina Langeland and Pål Aukrust

    Citation: BMC Infectious Diseases 2020 20:65

    Content type: Research article

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  30. Imported loiasis is a rare cause of consultation at the return of stay in central Africa, which often poses difficult diagnostic and therapeutic questions to practitioners especially those who are unaccustomed...

    Authors: Olivier Bouchaud, Sophie Matheron, Anne Loarec, Jean Dupouy Camet, Patrice Bourée, Nadine Godineau, Isabelle Poilane, Johann Cailhol and Eric Caumes

    Citation: BMC Infectious Diseases 2020 20:63

    Content type: Research article

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  31. Lymphedema is a public health problem in countries with lymphatic filariasis (LF) including Mali. We studied the epidemiology and clinical presentation of lymphedema in three previously LF-endemic health distr...

    Authors: Housseini Dolo, Yaya Ibrahim Coulibaly, Fatoumata Nene Konipo, Siaka Yamoussa Coulibaly, Salif Seriba Doumbia, Moussa Brema Sangare, Lamine Soumaoro, Michel Emmanuel Coulibaly, Abdallah Amadou Diallo, Yaye Diarra, Modibo Sangare, Seydou Doumbia, Robert Colebunders and Thomas B. Nutman

    Citation: BMC Infectious Diseases 2020 20:48

    Content type: Research article

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  32. It is believed that the current prevalence of malaria in endemic areas reflects selection for the carrier form of sickle cell trait through a survival advantage. Malaria has been incriminated as a great cause ...

    Authors: Ngo Linwa Esther Eleonore, Samuel Nambile Cumber, Eposse Ekoube Charlotte, Esuh Esong Lucas, Mandeng Ma Linwa Edgar, Claude Ngwayu Nkfusai, Meh Martin Geh, Budzi Michael Ngenge, Fala Bede, Nzozone Henry Fomukong, Henri Lucien Fouammo Kamga and Dora Mbanya

    Citation: BMC Infectious Diseases 2020 20:40

    Content type: Research article

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  33. Parasitic trichostrongyloid nematodes have a worldwide distribution in ruminants and frequently have been reported from humans in Middle and Far East, particularly in rural communities with poor personal hygie...

    Authors: Keyhan Ashrafi, Meysam Sharifdini, Zahra Heidari, Behnaz Rahmati and Eshrat Beigom Kia

    Citation: BMC Infectious Diseases 2020 20:28

    Content type: Research article

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  34. Toxocariasis is a worldwide zoonotic parasitic disease caused by species of Toxocara and Toxascaris, common in dogs and cats. Herein, a meta-analysis was contrived to assess the prevalence of Toxocara/Toxascaris ...

    Authors: Aida Vafae Eslahi, Milad Badri, Ali Khorshidi, Hamidreza Majidiani, Elham Hooshmand, Hamid Hosseini, Ali Taghipour, Masoud Foroutan, Nader Pestehchian, Farzaneh Firoozeh, Seyed Mohammad Riahi and Mohammad Zibaei

    Citation: BMC Infectious Diseases 2020 20:20

    Content type: Research article

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  35. Cryptosporidium is a genus of common intestinal protozoa, members of which cause diarrhea in a wide variety of hosts. Previous studies on Cryptosporidium in China have mainly focused on diarrhea sufferers, childr...

    Authors: Ning Xu, Hua Liu, Yanyan Jiang, Jianhai Yin, Zhongying Yuan, Yujuan Shen and Jianping Cao

    Citation: BMC Infectious Diseases 2020 20:16

    Content type: Research article

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  36. Determination of the prevalence and distribution pattern of intestinal parasites is a fundamental step to set up an effective control program to improve the health status. This study aimed to determine the pre...

    Authors: Mohammad Javad Abbaszadeh Afshar, Maryam Barkhori Mehni, Mostafa Rezaeian, Mehdi Mohebali, Vali Baigi, Somayeh Amiri, Mohammad Bagher Amirshekari, Ruhollah Hamidinia and Mohammad Samimi

    Citation: BMC Infectious Diseases 2020 20:12

    Content type: Research article

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  37. Toxoplasmosis is a common and serious parasitic infection caused by the ubiquitous obligatory intracellular protozoan organism, Toxoplasma gondii. Although infection with T. gondii is usually asymptomatic in heal...

    Authors: Abdulelah H. Al-Adhroey, Amat Al-Khaleq O. Mehrass, Abdulqawi A. Al-Shammakh, Abdullatif D. Ali, Mohammed Y. M. Akabat and Hesham M. Al-Mekhlafi

    Citation: BMC Infectious Diseases 2019 19:1089

    Content type: Research article

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  38. Egg-induced immune response and granuloma formation are thought to be the basis of central nervous system (CNS)-related clinical symptoms of Schistosoma japonicum. Microglia/macrophages are the major immune cells...

    Authors: Zhoubin Tan, Zhuowei Lei, Zhuo Zhang, Huaqiu Zhang, Kai Shu, Feng Hu and Ting Lei

    Citation: BMC Infectious Diseases 2019 19:1088

    Content type: Research article

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  39. Intestinal parasitic infection is one of the parasitic infections affecting people living in prison. Helminths and intestinal protozoan infections are the most common parasitic infection that may cause serious...

    Authors: Gemechu Ameya, Zerihun Zerdo, Mihret Tesfaye, Chimdo Jabesa, Abayneh Awaje, Kaleb Dejene, Petros Shika and Mohammed Eshetu

    Citation: BMC Infectious Diseases 2019 19:1086

    Content type: Research article

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  40. Schistosomiasis is known to induce inflammatory immune responses. C-reactive protein (CRP), resistin and P-selectin are serological inflammatory markers that rise during the acute stages of infection. Here, we...

    Authors: Theresa N. Chimponda, Caroline Mushayi, Derick N. M. Osakunor, Arthur Vengesai, Eyoh Enwono, Seth Amanfo, Janice Murray, Cremance Tshuma, Francisca Mutapi and Takafira Mduluza

    Citation: BMC Infectious Diseases 2019 19:1071

    Content type: Research article

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  41. Toxoplasmosis is caused by infection with the protozoan parasite Toxoplasma gondii. It is acquired by consumption of raw or undercooked meat containing tissue cyst, food or water contaminated with oocyst and cong...

    Authors: Demissie Assegu Fenta

    Citation: BMC Infectious Diseases 2019 19:1056

    Content type: Research article

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  42. Toxoplasma gondii is an opportunistic protozoan parasite that can infect all warm-blooded animals including humans and cause serious clinical manifestations. Toxoplasmosis can be diagnosed using histological, ser...

    Authors: Mert Döşkaya, Hüsnü Pullukçu, Muhammet Karakavuk, Esra Atalay Şahar, Mehmet Sezai Taşbakan, Meltem Işıkgöz Taşbakan, Mümtaz Yılmaz, Hüseyin Can, Aysu Değirmenci Döşkaya and Adnan Yüksel Gürüz

    Citation: BMC Infectious Diseases 2019 19:1042

    Content type: Research article

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  43. Treatment for severe malaria must be prompt with effective parenteral antimalarial drugs for at least 24 h to achieve fast parasite clearance, and when the patient can tolerate oral therapy, treatment should b...

    Authors: Pauline Byakika-Kibwika, Ronald Ssenyonga, Mohammed Lamorde, Daniel Blessborn and Joel Tarning

    Citation: BMC Infectious Diseases 2019 19:1025

    Content type: Research article

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  44. The present study aimed to demonstrate the applicability of a flow cytometry-based serology approach to identify spontaneous cure by the detection of immunoglobulin G, and also, the diagnosis and cure criterio...

    Authors: Andresa Pereira Oliveira Mendes, Beatriz Coutinho Oliveira, Allana Maria S. Pereira, Maria Carolina Accioly Brelaz Castro, Marina Assis Souza, Maria Edileuza Felinto Brito, Fernanda Fortes Araújo, Andrea Teixeira-Carvalho, Olindo Assis Martins-Filho and Valeria Rêgo Alves Pereira

    Citation: BMC Infectious Diseases 2019 19:1015

    Content type: Research article

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  45. Clonorchiasis, caused by Clonorchis sinensis (C. sinensis) infection, is a serious food-borne zoonotic disease that is often asymptomatic or shows only mild symptoms, which leads to delayed treatment and chronic ...

    Authors: Nan Wang, Bin Tang, Yuhua Hao, Xue Bai, Xuelin Wang, Yuxiang Li, Yong Yang, Shicun Li, Shuo Hao, Xinyu Wang, Mingyuan Liu and Xiaolei Liu

    Citation: BMC Infectious Diseases 2019 19:1014

    Content type: Case report

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  46. Despite substantial global effort and updated clinical management guidelines, diarrhea continues to be among leading worldwide causes of morbidity and mortality in children. Infectious diarrhea, the most commo...

    Authors: Getachew Kabew Mekonnen, Bezatu Mengistie, Geremew Sahilu, Helmut Kloos and Worku Mulat

    Citation: BMC Infectious Diseases 2019 19:1008

    Content type: Research article

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  47. Lupoid cutaneous leishmaniasis (LCL) is known as a rare but serious complication of anthroponotic cutaneous leishmaniasis (ACL) resistant to conventional treatments. Sodium chlorosum, a pro-oxidative preparation ...

    Authors: Sara Molkara, Elaheh Poursoltani, Kurt-Wilhelm Stahl, Masoud Maleki, Ali Khamesipour, Christian Bogdan, Maryam Salehi and Vahid Mashayekhi Goyonlo

    Citation: BMC Infectious Diseases 2019 19:1005

    Content type: Research article

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  48. Recent studies have shown that CD103 is an important marker for tissue-resident memory T cells (TRM) which plays an important role in anti-infection. However, the role of CD103+ TRM was not elucidated in the prog...

    Authors: Yi Zhao, Quan Yang, Chenxi Jin, Yuanfa Feng, Shihao Xie, Hongyan Xie, Yanwei Qi, Huaina Qiu, Hongyuan Chen, Ailin Tao, Jianbing Mu, Wenjuan Qin and Jun Huang

    Citation: BMC Infectious Diseases 2019 19:999

    Content type: Research article

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