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Parasitological diseases

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of parasitological diseases in humans, as well as related studies on molecular and cellular biology, pathophysiology, and epidemiology.

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  1. American tegumentary leishmaniasis (ATL) is a widespread anthropozoonosis caused by protozoa of the genus Leishmania and is considered a serious public health problem. The aim of this study was to provide a descr...

    Authors: Mariana Olímpia Köhler Marra Pinto, Tiago Mendonça de Oliveira, Andreza Nayla de Assis Aguiar, Paulo Eustáquio Marra Pinto, David Soeiro Barbosa, Soraia de Araújo Diniz and Marcos Xavier Silva

    Citation: BMC Infectious Diseases 2020 20:163

    Content type: Research article

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  2. Intestinal infection is still an important public health problem in low-income countries. Food handlers may be infected by a wide range of enteropathogens and have been implicated in the transmission of many i...

    Authors: Birhan Alemnew, Getnet Gedefaw, Gedefaw Diress and Asmamaw Demis Bizuneh

    Citation: BMC Infectious Diseases 2020 20:156

    Content type: Research article

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  3. Chagas disease is caused by the haemoflagellate protozoan Trypanosoma cruzi. Currently, T. cruzi recognizes seven discrete typing units (DTUs): TcI to TcVI and Tcbat. The genetic diversity of T. cruzi is suspecte...

    Authors: Manuel Calvopina, Gabriela Segovia, William Cevallos, Yosselin Vicuña, Jaime A. Costales and Angel Guevara

    Citation: BMC Infectious Diseases 2020 20:143

    Content type: Case report

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  4. Globally, Taenia solium can cause cysticercosis in humans (including neurocysticercosis) and in pigs through ingestion of eggs and taeniasis in humans through ingestion of raw/undercooked pork contaminated with m...

    Authors: Msawenkosi I. Sithole, Johan L. Bekker and Samson Mukaratirwa

    Citation: BMC Infectious Diseases 2020 20:107

    Content type: Research article

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  5. The immune response during falciparum malaria mediates both harmful and protective effects on the host; however the participating molecules have not been fully defined. Interleukin (IL)-27 is a pleiotropic cyt...

    Authors: Kari Otterdal, Aase Berg, Annika E. Michelsen, Sam Patel, Ida Gregersen, Ellen Lund Sagen, Bente Halvorsen, Arne Yndestad, Thor Ueland, Nina Langeland and Pål Aukrust

    Citation: BMC Infectious Diseases 2020 20:65

    Content type: Research article

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  6. Imported loiasis is a rare cause of consultation at the return of stay in central Africa, which often poses difficult diagnostic and therapeutic questions to practitioners especially those who are unaccustomed...

    Authors: Olivier Bouchaud, Sophie Matheron, Anne Loarec, Jean Dupouy Camet, Patrice Bourée, Nadine Godineau, Isabelle Poilane, Johann Cailhol and Eric Caumes

    Citation: BMC Infectious Diseases 2020 20:63

    Content type: Research article

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  7. Lymphedema is a public health problem in countries with lymphatic filariasis (LF) including Mali. We studied the epidemiology and clinical presentation of lymphedema in three previously LF-endemic health distr...

    Authors: Housseini Dolo, Yaya Ibrahim Coulibaly, Fatoumata Nene Konipo, Siaka Yamoussa Coulibaly, Salif Seriba Doumbia, Moussa Brema Sangare, Lamine Soumaoro, Michel Emmanuel Coulibaly, Abdallah Amadou Diallo, Yaye Diarra, Modibo Sangare, Seydou Doumbia, Robert Colebunders and Thomas B. Nutman

    Citation: BMC Infectious Diseases 2020 20:48

    Content type: Research article

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  8. It is believed that the current prevalence of malaria in endemic areas reflects selection for the carrier form of sickle cell trait through a survival advantage. Malaria has been incriminated as a great cause ...

    Authors: Ngo Linwa Esther Eleonore, Samuel Nambile Cumber, Eposse Ekoube Charlotte, Esuh Esong Lucas, Mandeng Ma Linwa Edgar, Claude Ngwayu Nkfusai, Meh Martin Geh, Budzi Michael Ngenge, Fala Bede, Nzozone Henry Fomukong, Henri Lucien Fouammo Kamga and Dora Mbanya

    Citation: BMC Infectious Diseases 2020 20:40

    Content type: Research article

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  9. Parasitic trichostrongyloid nematodes have a worldwide distribution in ruminants and frequently have been reported from humans in Middle and Far East, particularly in rural communities with poor personal hygie...

    Authors: Keyhan Ashrafi, Meysam Sharifdini, Zahra Heidari, Behnaz Rahmati and Eshrat Beigom Kia

    Citation: BMC Infectious Diseases 2020 20:28

    Content type: Research article

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  10. Toxocariasis is a worldwide zoonotic parasitic disease caused by species of Toxocara and Toxascaris, common in dogs and cats. Herein, a meta-analysis was contrived to assess the prevalence of Toxocara/Toxascaris ...

    Authors: Aida Vafae Eslahi, Milad Badri, Ali Khorshidi, Hamidreza Majidiani, Elham Hooshmand, Hamid Hosseini, Ali Taghipour, Masoud Foroutan, Nader Pestehchian, Farzaneh Firoozeh, Seyed Mohammad Riahi and Mohammad Zibaei

    Citation: BMC Infectious Diseases 2020 20:20

    Content type: Research article

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  11. Cryptosporidium is a genus of common intestinal protozoa, members of which cause diarrhea in a wide variety of hosts. Previous studies on Cryptosporidium in China have mainly focused on diarrhea sufferers, childr...

    Authors: Ning Xu, Hua Liu, Yanyan Jiang, Jianhai Yin, Zhongying Yuan, Yujuan Shen and Jianping Cao

    Citation: BMC Infectious Diseases 2020 20:16

    Content type: Research article

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  12. Determination of the prevalence and distribution pattern of intestinal parasites is a fundamental step to set up an effective control program to improve the health status. This study aimed to determine the pre...

    Authors: Mohammad Javad Abbaszadeh Afshar, Maryam Barkhori Mehni, Mostafa Rezaeian, Mehdi Mohebali, Vali Baigi, Somayeh Amiri, Mohammad Bagher Amirshekari, Ruhollah Hamidinia and Mohammad Samimi

    Citation: BMC Infectious Diseases 2020 20:12

    Content type: Research article

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  14. Toxoplasmosis is a common and serious parasitic infection caused by the ubiquitous obligatory intracellular protozoan organism, Toxoplasma gondii. Although infection with T. gondii is usually asymptomatic in heal...

    Authors: Abdulelah H. Al-Adhroey, Amat Al-Khaleq O. Mehrass, Abdulqawi A. Al-Shammakh, Abdullatif D. Ali, Mohammed Y. M. Akabat and Hesham M. Al-Mekhlafi

    Citation: BMC Infectious Diseases 2019 19:1089

    Content type: Research article

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  15. Egg-induced immune response and granuloma formation are thought to be the basis of central nervous system (CNS)-related clinical symptoms of Schistosoma japonicum. Microglia/macrophages are the major immune cells...

    Authors: Zhoubin Tan, Zhuowei Lei, Zhuo Zhang, Huaqiu Zhang, Kai Shu, Feng Hu and Ting Lei

    Citation: BMC Infectious Diseases 2019 19:1088

    Content type: Research article

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  16. Intestinal parasitic infection is one of the parasitic infections affecting people living in prison. Helminths and intestinal protozoan infections are the most common parasitic infection that may cause serious...

    Authors: Gemechu Ameya, Zerihun Zerdo, Mihret Tesfaye, Chimdo Jabesa, Abayneh Awaje, Kaleb Dejene, Petros Shika and Mohammed Eshetu

    Citation: BMC Infectious Diseases 2019 19:1086

    Content type: Research article

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  17. Schistosomiasis is known to induce inflammatory immune responses. C-reactive protein (CRP), resistin and P-selectin are serological inflammatory markers that rise during the acute stages of infection. Here, we...

    Authors: Theresa N. Chimponda, Caroline Mushayi, Derick N. M. Osakunor, Arthur Vengesai, Eyoh Enwono, Seth Amanfo, Janice Murray, Cremance Tshuma, Francisca Mutapi and Takafira Mduluza

    Citation: BMC Infectious Diseases 2019 19:1071

    Content type: Research article

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  19. Toxoplasmosis is caused by infection with the protozoan parasite Toxoplasma gondii. It is acquired by consumption of raw or undercooked meat containing tissue cyst, food or water contaminated with oocyst and cong...

    Authors: Demissie Assegu Fenta

    Citation: BMC Infectious Diseases 2019 19:1056

    Content type: Research article

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  20. Toxoplasma gondii is an opportunistic protozoan parasite that can infect all warm-blooded animals including humans and cause serious clinical manifestations. Toxoplasmosis can be diagnosed using histological, ser...

    Authors: Mert Döşkaya, Hüsnü Pullukçu, Muhammet Karakavuk, Esra Atalay Şahar, Mehmet Sezai Taşbakan, Meltem Işıkgöz Taşbakan, Mümtaz Yılmaz, Hüseyin Can, Aysu Değirmenci Döşkaya and Adnan Yüksel Gürüz

    Citation: BMC Infectious Diseases 2019 19:1042

    Content type: Research article

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  21. Treatment for severe malaria must be prompt with effective parenteral antimalarial drugs for at least 24 h to achieve fast parasite clearance, and when the patient can tolerate oral therapy, treatment should b...

    Authors: Pauline Byakika-Kibwika, Ronald Ssenyonga, Mohammed Lamorde, Daniel Blessborn and Joel Tarning

    Citation: BMC Infectious Diseases 2019 19:1025

    Content type: Research article

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  22. The present study aimed to demonstrate the applicability of a flow cytometry-based serology approach to identify spontaneous cure by the detection of immunoglobulin G, and also, the diagnosis and cure criterio...

    Authors: Andresa Pereira Oliveira Mendes, Beatriz Coutinho Oliveira, Allana Maria S. Pereira, Maria Carolina Accioly Brelaz Castro, Marina Assis Souza, Maria Edileuza Felinto Brito, Fernanda Fortes Araújo, Andrea Teixeira-Carvalho, Olindo Assis Martins-Filho and Valeria Rêgo Alves Pereira

    Citation: BMC Infectious Diseases 2019 19:1015

    Content type: Research article

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  23. Clonorchiasis, caused by Clonorchis sinensis (C. sinensis) infection, is a serious food-borne zoonotic disease that is often asymptomatic or shows only mild symptoms, which leads to delayed treatment and chronic ...

    Authors: Nan Wang, Bin Tang, Yuhua Hao, Xue Bai, Xuelin Wang, Yuxiang Li, Yong Yang, Shicun Li, Shuo Hao, Xinyu Wang, Mingyuan Liu and Xiaolei Liu

    Citation: BMC Infectious Diseases 2019 19:1014

    Content type: Case report

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  24. Despite substantial global effort and updated clinical management guidelines, diarrhea continues to be among leading worldwide causes of morbidity and mortality in children. Infectious diarrhea, the most commo...

    Authors: Getachew Kabew Mekonnen, Bezatu Mengistie, Geremew Sahilu, Helmut Kloos and Worku Mulat

    Citation: BMC Infectious Diseases 2019 19:1008

    Content type: Research article

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  25. Lupoid cutaneous leishmaniasis (LCL) is known as a rare but serious complication of anthroponotic cutaneous leishmaniasis (ACL) resistant to conventional treatments. Sodium chlorosum, a pro-oxidative preparation ...

    Authors: Sara Molkara, Elaheh Poursoltani, Kurt-Wilhelm Stahl, Masoud Maleki, Ali Khamesipour, Christian Bogdan, Maryam Salehi and Vahid Mashayekhi Goyonlo

    Citation: BMC Infectious Diseases 2019 19:1005

    Content type: Research article

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  26. Recent studies have shown that CD103 is an important marker for tissue-resident memory T cells (TRM) which plays an important role in anti-infection. However, the role of CD103+ TRM was not elucidated in the prog...

    Authors: Yi Zhao, Quan Yang, Chenxi Jin, Yuanfa Feng, Shihao Xie, Hongyan Xie, Yanwei Qi, Huaina Qiu, Hongyuan Chen, Ailin Tao, Jianbing Mu, Wenjuan Qin and Jun Huang

    Citation: BMC Infectious Diseases 2019 19:999

    Content type: Research article

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  27. Current available treatments (benznidazole and nifurtimox) for Chagas disease (CD) show limited efficacy in chronic phase and frequent undesirable effects. Ergosterol synthesis inhibitors (ESI) had been consid...

    Authors: Pau Bosch-Nicolau, Fernando Salvador, Adrián Sánchez-Montalvá, Elena Sulleiro, Joaquín Burgos and Israel Molina

    Citation: BMC Infectious Diseases 2019 19:956

    Content type: Case report

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  28. Malaria is the fifth leading cause of death worldwide. Pakistan is considered as a moderate malaria-endemic country but still, 177 million individuals are at risk of malaria. Roughly 60% of Pakistan’s populati...

    Authors: Naveeda Akhtar Qureshi, Huma Fatima, Muhammad Afzal, Aamir Ali Khattak and Muhammad Ali Nawaz

    Citation: BMC Infectious Diseases 2019 19:935

    Content type: Research article

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    The Correction to this article has been published in BMC Infectious Diseases 2020 20:25

  29. Echinococcosis is a zoonotic disease caused by the larval stages of taeniid cestodes of the genus Echinococcus. The two major types of infection in humans are cystic echinococcosis (CE) or hydatidosis and alveola...

    Authors: Shima Mahmoudi, Setareh Mamishi, Maryam Banar, Babak Pourakbari and Hossein Keshavarz

    Citation: BMC Infectious Diseases 2019 19:929

    Content type: Research article

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  30. In southern Papua, Indonesia, malaria is highly prevalent in young children and is a significant cause of morbidity and early mortality. The association between malaria and delayed mortality is unknown.

    Authors: Dewi Patriani, Eggi Arguni, Enny Kenangalem, Saber Dini, Paulus Sugiarto, Afdhal Hasanuddin, Daniel Adrian Lampah, Nicholas M. Douglas, Nicholas M. Anstey, Julie Anne Simpson, Ric N. Price and Jeanne Rini Poespoprodjo

    Citation: BMC Infectious Diseases 2019 19:922

    Content type: Research article

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  31. The only licensed malaria vaccine, RTS,S/AS01, has been developed for morbidity-control in young children. The potential impact on transmission of deploying such anti-infective vaccines to wider age ranges, po...

    Authors: Flavia Camponovo, Chris F. Ockenhouse, Cynthia Lee and Melissa A. Penny

    Citation: BMC Infectious Diseases 2019 19:920

    Content type: Research article

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  32. Leishmania infantum, the etiological agent of visceral leishmaniasis, is a neglected zoonosis that requires validation and standardization of satisfactory diagnostic methodologies. Thus, the aim of the present st...

    Authors: Ryan Emiliano da Silva, Bruna Matarucco Sampaio, Renata Tonhosolo, Andrea Perei ra da Costa, Luiz Eduardo da Silva Costa, Fernanda Ap. Nieri-Bastos, Márcia Aparecida Sperança and Arlei Marcili

    Citation: BMC Infectious Diseases 2019 19:895

    Content type: Research article

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  33. Blastocystis is one of the most common intestinal protozoa in human faecal samples with uncertain impact on public health. Studies on the prevalence of Blastocystis in HIV-positive patients are limited and dated.

    Authors: Lucia Fontanelli Sulekova, Simona Gabrielli, Federica Furzi, Giovanni Luigi Milardi, Elisa Biliotti, Maurizio De Angelis, Giancarlo Iaiani, Caterina Fimiani, Myriam Maiorano, Simonetta Mattiucci and Gloria Taliani

    Citation: BMC Infectious Diseases 2019 19:876

    Content type: Research article

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  34. Leishmaniasis is an emerging infectious disease. Due to human migration and tourism, visceral leishmaniasis may become more common in non-endemic areas. In the Mediterranean basin, visceral leishmaniasis typic...

    Authors: Iratxe Martinez de Narvajas, Alba Díaz, Octavio Bassegoda, Adriá Carpio, Carla Fuster, María Eugenia Valls, Miriam J. Alvarez-Martínez, Carolina García-Vidal, Alejandro Soriano, José Antonio Martínez and Juan Ambrosioni

    Citation: BMC Infectious Diseases 2019 19:874

    Content type: Case report

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  35. Drug resistant malaria is a growing concern in the Democratic Republic of the Congo (DRC), where previous studies indicate that parasites resistant to sulfadoxine/pyrimethamine or chloroquine are spatially clu...

    Authors: Molly Deutsch-Feldman, Ozkan Aydemir, Margaret Carrel, Nicholas F. Brazeau, Samir Bhatt, Jeffrey A. Bailey, Melchior Kashamuka, Antoinette K. Tshefu, Steve M. Taylor, Jonathan J. Juliano, Steven R. Meshnick and Robert Verity

    Citation: BMC Infectious Diseases 2019 19:872

    Content type: Research article

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  36. Cutaneous leishmaniasis is one of the neglected tropical diseases in the Ethiopian highlands and studies on assessment of knowledge, attitude and practice of the community in endemic areas are scanty. The stud...

    Authors: Helina Fikre Tamiru, Yohana James Mashalla, Rezika Mohammed and Gloria Thupayagale Tshweneagae

    Citation: BMC Infectious Diseases 2019 19:855

    Content type: Research article

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  37. Taenia hydatigena, T. multiceps, T. pisiformis, and Dipylidium caninum are four common large and medium-sized tapeworms parasitizing the small intestine of dogs and other canids. These parasites cause serious imp...

    Authors: Guo-Qiang Zhu, Li Li, John Asekhaen Ohiolei, Yan-Tao Wu, Wen-Hui Li, Nian-Zhang Zhang, Bao-Quan Fu, Hong-Bin Yan and Wan-Zhong Jia

    Citation: BMC Infectious Diseases 2019 19:854

    Content type: Research article

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  38. Leishmaniasis and malaria are tropical diseases with more than half of the world population at risk of infection resulting in significant morbidity and mortality. Co-infection of Leishmaniasis and malaria pose...

    Authors: Pragya Gautam Ghimire, Prasanna Ghimire, Jyoti Adhikari and Anurag Chapagain

    Citation: BMC Infectious Diseases 2019 19:849

    Content type: Case report

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  39. Helminthic and protozoan infections are common, particularly in low- or middle-income countries. Although an association between parasite carriage and markers of poor growth have been shown in some studies, sy...

    Authors: Timothy P. W. Jones, John D. Hart, Khumbo Kalua and Robin L. Bailey

    Citation: BMC Infectious Diseases 2019 19:838

    Content type: Research article

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  40. Intestinal schistosomiasis is highly endemic in Tanzania and mass drug administration (MDA) using praziquantel is the mainstay of the control program. However, the MDA program covers only school aged children ...

    Authors: Andreas Mueller, Antje Fuss, Uwe Ziegler, Godfrey M. Kaatano and Humphrey D. Mazigo

    Citation: BMC Infectious Diseases 2019 19:832

    Content type: Research article

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  41. The association between Toxoplasma gondii infection and thyroid disease has been poorly studied. Therefore, we sought to determine the association between T. gondii seropositivity and thyroid dysfunction.

    Authors: Cosme Alvarado-Esquivel, Agar Ramos-Nevarez, Carlos Alberto Guido-Arreola, Sandra Margarita Cerrillo-Soto, Alma Rosa Pérez-Álamos, Sergio Estrada-Martínez, Verónica Dayali Gutierrez-Martinez, Antonio Sifuentes-Alvarez, Eda Guadalupe Ramírez-Valles and Edith Contreras-Cisneros

    Citation: BMC Infectious Diseases 2019 19:826

    Content type: Research article

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  42. Current guidelines and targets for soil-transmitted helminth (STH) control focus on school-based deworming for school-age children, given the high risk of associated morbidity in this age group. However, expan...

    Authors: Naomi E. Clarke, Dinh Ng-Nguyen, Rebecca J. Traub, Archie C. A. Clements, Kate Halton, Roy M. Anderson, Darren J. Gray, Luc E. Coffeng, John M. Kaldor and Susana Vaz Nery

    Citation: BMC Infectious Diseases 2019 19:822

    Content type: Study protocol

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  43. Enterocytozoon bieneusi and Cryptosporidium spp. are prevalent zoonotic parasites associated with a high burden among children. To date only limited molecular epidemiological data on E. bieneusi and Cryptosporidi...

    Authors: Rapeepun Prasertbun, Hirotake Mori, Yaowalark Sukthana, Supaluk Popruk, Teera Kusolsuk, Katsuro Hagiwara and Aongart Mahittikorn

    Citation: BMC Infectious Diseases 2019 19:808

    Content type: Research article

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  44. Scabies, a parasitic disease of the skin, is a major public health problem, largely affecting children. Scabies is often complicated by impetigo which can result in serious complications including invasive inf...

    Authors: Millicent H. Osti, Oliver Sokana, Sophie Phelan, Michael Marks, Margot J. Whitfeld, Christina Gorae, John M. Kaldor, Andrew C. Steer and Daniel Engelman

    Citation: BMC Infectious Diseases 2019 19:803

    Content type: Research article

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  45. Larviciding is an effective supplementary tool for malaria vector control, but the identification and accessibility of aquatic habitats impedes application. Dissemination of the insect growth regulator, pyripr...

    Authors: Oscar Mbare, Steven W. Lindsay and Ulrike Fillinger

    Citation: BMC Infectious Diseases 2019 19:800

    Content type: Research article

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  46. Alveolar echinococcosis (AE) is caused by the larval stage of Echinococcus multilocularis (E. multilocularis), and considered as public health issue. Parasite-host immune interaction is pivotal during infection. ...

    Authors: Abuduaini Abulizi, Yingmei Shao, Tuerganaili Aji, Zhide Li, Chuanshan Zhang, Abudusalamu Aini, Hui Wang, Tuerhongjiang Tuxun, Liang Li, Ning Zhang, Renyong Lin and Hao Wen

    Citation: BMC Infectious Diseases 2019 19:792

    Content type: Research article

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  47. Due to the similarity of Strongyloides stercoralis with free-living nematodes of Rhabditis species they might be miss-diagnosed with each other in microscopical examination of stool samples. The aim of this study...

    Authors: Mandana Fadaei Tehrani, Meysam Sharifdini, Farzaneh Zahabiun, Robabeh Latifi and Eshrat Beigom Kia

    Citation: BMC Infectious Diseases 2019 19:776

    Content type: Research article

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  48. Sparganosis, a rare and severe parasitic infection caused by the larvae of Spirometra species or simply sparganum, generally involves subcutaneous tissue or muscle. But occasionally, sparganum can also invade the...

    Authors: Yueli Zhu, Lingqi Ye, Xiansan Ding, Jimin Wu and Yanxing Chen

    Citation: BMC Infectious Diseases 2019 19:748

    Content type: Case report

    Published on:

  49. Leishmaniasis caused by different species of Leishmania affect 98 countries worldwide. Visceral Leishmaniasis (VL) is the mortal clinical presentation of the disease that causes the dead to more than 90% of the p...

    Authors: Giovanny Herrera, Adriana Castillo, Martha S. Ayala, Carolina Flórez, Omar Cantillo-Barraza and Juan David Ramirez

    Citation: BMC Infectious Diseases 2019 19:747

    Content type: Research article

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  50. Schistosomiasis and soil-transmitted helminth infections are among the most chronic infections worldwide. Based on their demonstrable impact on human health, the WHO recently recommended the implementation of ...

    Authors: Hlengiwe Sacolo-Gwebu, Muhubiri Kabuyaya and Moses Chimbari

    Citation: BMC Infectious Diseases 2019 19:734

    Content type: Research article

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