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Parasitological diseases

Section edited by Honorine Ward & Laith Yakob 

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of parasitological diseases in humans, as well as related studies on molecular and cellular biology, pathophysiology, and epidemiology.

Page 1 of 7

  1. Content type: Research article

    Intestinal parasites still pose major public health problems in developing countries like Ethiopia. Local epidemiological data is indispensable in order to design and monitor prevention and control strategies....

    Authors: Getaneh Alemu, Ashenafi Abossie and Zerihun Yohannes

    Citation: BMC Infectious Diseases 2019 19:270

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  2. Content type: Study protocol

    Soil-transmitted helminthiasis affects almost 2 billion people worldwide in tropical climates. Preventive chemotherapy, using the benzimidazoles (albendazole and mebendazole) is the current main recommended co...

    Authors: Chandni Patel, Eveline Hürlimann, Ladina Keller, Jan Hattendorf, Somphou Sayasone, Said M Ali, Shaali M Ame, Jean T Coulibaly and Jennifer Keiser

    Citation: BMC Infectious Diseases 2019 19:262

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  3. Content type: Research article

    Environmental, social, geographical, and other factors could affect the distribution of intestinal parasites. Parasitic infections would impose on health and social problems like mal-absorption, diarrhea, impa...

    Authors: Habtamu Sewunet Mekonnen and Daniale Tekelia Ekubagewargies

    Citation: BMC Infectious Diseases 2019 19:256

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  4. Content type: Research article

    Chronic Chagas Disease (CD) diagnosis is based on serological methods employing crude, semipurified or recombinant antigens, which may result in low sensitivity or cross-reactivity. To reduce these restriction...

    Authors: Eva Dopico, Rodrigo Pimenta Del-Rei, Bertha Espinoza, Itziar Ubillos, Nilson Ivo Tonin Zanchin, Elena Sulleiro, Zaira Moure, Paola Alejandra Fiorani Celedon, Wayner Vieira Souza, Edimilson Domingos da Silva, Yara Miranda Gomes and Fred Luciano Neves Santos

    Citation: BMC Infectious Diseases 2019 19:251

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  5. Content type: Research article

    The WHO recommends single low-dose primaquine (SLDPQ, 0.25 mg/kg body weight) in falciparum-infected patients to block malaria transmission and contribute to eliminating multidrug resistant Plasmodium falciparum ...

    Authors: Lek Dysoley, Saorin Kim, Sergio Lopes, Nimol Khim, Steven Bjorges, Samphornarann Top, Chea Huch, Huy Rekol, Nelli Westercamp, Mark M. Fukuda, Jimee Hwang, Arantxa Roca-Feltrer, Mavuto Mukaka, Didier Menard and Walter R. Taylor

    Citation: BMC Infectious Diseases 2019 19:250

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  6. Content type: Research article

    Malaria and leishmaniasis are the two largest parasitic killers in the world. Due togeographical overlap of these diseases, malaria-visceral leishmaniasis co-infections occur in large populations and exist in ...

    Authors: Yibeltal Aschale, Animen Ayehu, Ligabaw Worku, Habtie Tesfa, Meseret Birhanie and Wossenseged Lemma

    Citation: BMC Infectious Diseases 2019 19:239

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  7. Content type: Research article

    Schistosomiasis is a devastating parasitic disease. The mainstay of schistosomiasis control is by praziquantel treatment. The study aimed to determine benefits of annual chemotherapy of schistosomiasis on deve...

    Authors: Tawanda J. Chisango, Bongiwe Ndlovu, Arthur Vengesai, Agness Farai Nhidza, Edson P. Sibanda, Danai Zhou, Francisca Mutapi and Takafira Mduluza

    Citation: BMC Infectious Diseases 2019 19:219

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  8. Content type: Research article

    Accurate diagnosis of Toxoplasma gondii (T. gondii) infection remains elusive and requires a comprehensive assessment through laboratory and clinical investigation. In this study, a diagnostic algorithm based on ...

    Authors: Padmaloseni Thangarajah, Khalid Hajissa, Weng Kin Wong, Muhammad Amiruddin Abdullah, Nabilah Ismail and Zeehaida Mohamed

    Citation: BMC Infectious Diseases 2019 19:202

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  9. Content type: Research article

    Infestations with scabies mites are a global burden affecting individuals of all ages, classes and ethnicities. As poor sanitation and overcrowding favor the transmission of this highly contagious disease, epi...

    Authors: Simon M. Mueller, Stefan Gysin, Michael Schweitzer, Simon Schwegler, Peter Haeusermann, Peter Itin, Thomas Bart, Ruth Spieler Denz, Thomas Steffen, Richard Kuehl, Andreas F. Widmer and Oliver Brandt

    Citation: BMC Infectious Diseases 2019 19:200

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  10. Content type: Research article

    Parasitic infections, particularly those caused by protozoa, represent a considerable public health problem in developing countries. Blastocystis, Giardia duodenalis, Cryptosporidium spp. and the Entamoeba comple...

    Authors: Ximena Villamizar, Adriana Higuera, Giovanny Herrera, Luis Reinel Vasquez-A, Lorena Buitron, Lina Maria Muñoz, Fabiola E. Gonzalez-C, Myriam Consuelo Lopez, Julio Cesar Giraldo and Juan David Ramírez

    Citation: BMC Infectious Diseases 2019 19:190

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  11. Content type: Debate

    Taenia solium taeniosis/cysticercosis is a public health and agricultural problem, especially in low-income countries, and has been ranked the top foodborne parasitic hazard globally. In 2012, the World Health Or...

    Authors: Uffe Christian Braae, Sarah Gabriël, Chiara Trevisan, Lian F. Thomas, Pascal Magnussen, Bernadette Abela-Ridder, Helena Ngowi and Maria Vang Johansen

    Citation: BMC Infectious Diseases 2019 19:182

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  12. Content type: Research article

    Prevalence of schistosomiasis is high among children under five years in Uganda. Schistosomiasis control efforts over time have included periodic mass treatments in endemic areas for adults and school going ch...

    Authors: Simon Peter Sebina Kibira, John C. Ssempebwa, Ronald Ssenyonga, Scott Radloff and Fredrick Edward Makumbi

    Citation: BMC Infectious Diseases 2019 19:165

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  13. Content type: Research article

    Loiasis is a vector-borne parasitic disease due to Loa loa and transmitted to humans by tabanids of the genus Chrysops. Loiasis has been historically considered as the second or third most common reason for medic...

    Authors: Aude E. Mogoung-Wafo, Hugues C. Nana-Djeunga, André Domche, Floribert Fossuo-Thotchum, Jean Bopda, Steve Mbickmen-Tchana, Honoré Djomo-Kamga and Joseph Kamgno

    Citation: BMC Infectious Diseases 2019 19:146

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  14. Content type: Research article

    Soil-transmitted helminthic (STH) infections are common in Sub-Saharan Africa. One method used for control of these helminths is mass anti-helminthic administration in populations at risk of STH infections. In...

    Authors: Abdulazeez Imam, Zubaida L. Farouk, Fatimah Hassan-Hanga and Uchechukwu G. Ihesiulor

    Citation: BMC Infectious Diseases 2019 19:121

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  15. Content type: Case report

    Clonorchiasis is the common parasitic infection in the general population of the Republic of Korea, however, taeniasis is scarcely reported recently. Here, we describe a case of co-infection with the cestode T. s...

    Authors: Ju Hyeon Shin, Eun Jeong Won, Jee Seung Jung, Kyung-Hwa Park, Kwang Il Nam, Soo Hyun Kim and Jong Hee Shin

    Citation: BMC Infectious Diseases 2019 19:115

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  16. Content type: Research article

    Cutaneous leishmaniasis (CL) caused by Leishmania species, is a geographically extensive disease that infects humans and animals. CL is endemic in half of the 31 provinces of Iran, with 29,201 incidence cases rep...

    Authors: Iraj Mohammadpour, Gholam Reza Hatam, Farhad Handjani, Farzaneh Bozorg-Ghalati, Daniel PourKamal and Mohammad Hossein Motazedian

    Citation: BMC Infectious Diseases 2019 19:98

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  17. Content type: Research article

    Making a definite diagnosis of infectious uveitis is a challenging task because many other infectious, and non-infectious uveitis, may have similar non-specific symptoms and overlapping clinical appearances. C...

    Authors: Alejandra de-la-Torre, Juanita Valdés-Camacho, Clara López de Mesa, Andrés Uauy-Nazal, Juan David Zuluaga, Lina María Ramírez-Páez, Felipe Durán, Elizabeth Torres-Morales, Jessica Triviño, Mateo Murillo, Alba Cristina Peñaranda, Juan Carlos Sepúlveda-Arias and Jorge Enrique Gómez-Marín

    Citation: BMC Infectious Diseases 2019 19:91

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  18. Content type: Research article

    Malaria clinical outcomes vary by erythrocyte characteristics, including ABO blood group, but the effect of ABO blood group on asymptomatic, uncomplicated and placental Plasmodium falciparum (P. falciparum) infec...

    Authors: Abraham Degarege, Merhawi T. Gebrezgi, Consuelo M. Beck-Sague, Mats Wahlgren, Luiz Carlos de Mattos and Purnima Madhivanan

    Citation: BMC Infectious Diseases 2019 19:86

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  19. Content type: Research article

    Human schistosomiases are acute and chronic infectious diseases of poverty. Currently, epidemiological data of urinary schistosomiasis (US) in school-age children (SAC) and adults are often reported together m...

    Authors: Tolulope Ebenezer Atalabi and Taiwo Oluwakemi Adubi

    Citation: BMC Infectious Diseases 2019 19:73

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  20. Content type: Case report

    Visceral leishmaniasis (VL) is becoming endemic in São Paulo state, in the southeastern region of Brazil. Unusual manifestations with non-specific signs and symptoms may make diagnosis difficult and delay trea...

    Authors: Luiz Euribel Prestes-Carneiro, Patricia Rodrigues Naufal Spir, Mateus Fontanesi, Karen Gabriella Pereira Garcia, Francisco Assis da Silva, Edilson Ferreira Flores and Dewton de Moraes Vasconcelos

    Citation: BMC Infectious Diseases 2019 19:70

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  21. Content type: Case report

    Cystic echinococcosis (CE) is a worldwide zoonosis and the liver is the most commonly affected organ. Clinical manifestations range from completely asymptomatic cysts to a potential lethal cyst rupture and ana...

    Authors: Flaminia Coluzzi, Roberto Luca Meniconi, Damiano Caruso, Flaminia Rivosecchi, Linda Petrone, Delia Goletti and Giuseppe Maria Ettorre

    Citation: BMC Infectious Diseases 2019 19:37

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  22. Content type: Case report

    Hepatic clonorchiasis is one of the most prevalent food-borne parasitic diseases worldwide. Clonorchis sinensis, the pathogen, is the major parasitic trigger contributing to cholangitis, cholelithiasis, and even ...

    Authors: Xialei Liu, Genglong Zhu, Chaonong Cai, Zhiyue Lv and Jian Li

    Citation: BMC Infectious Diseases 2019 19:33

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  23. Content type: Research article

    Cutaneous leishmaniasis (CL) is a serious health problem in Suriname. To expand the diagnostic options, two newly developed diagnostic tests, i.e. the rapid diagnostic test CL Detect™ Rapid Test (CL Detect) an...

    Authors: Henk D. F. H. Schallig, Ricardo V. P. Hu, Alida D. Kent, Merlin van Loenen, Sandra Menting, Albert Picado, Zippora Oosterling and Israel Cruz

    Citation: BMC Infectious Diseases 2019 19:25

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  24. Content type: Research article

    Visceral leishmaniasis (VL) is a neglected tropical disease of public health relevance in Brazil. To prioritize disease control measures, the Secretaria de Vigilância em Saúde of Brazil’s Ministry of Health (S...

    Authors: Gustavo Machado, Julio Alvarez, Haakon Christopher Bakka, Andres Perez, Lucas Edel Donato, Francisco Edilson de Ferreira Lima Júnior, Renato Vieira Alves and Victor Javier Del Rio Vilas

    Citation: BMC Infectious Diseases 2019 19:2

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  25. Content type: Case report

    We report on a 21-year-old patient with a giant symptomatic hydatid cyst of the interventricular septum, to whom a staged management approach was employed. Induction medical therapy led to a reduction in the s...

    Authors: Jadranka Separovic Hanzevacki, Hrvoje Gasparovic, Vlatka Reskovic Luksic, Zvonimir Ostojic and Bojan Biocina

    Citation: BMC Infectious Diseases 2018 18:694

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  26. Content type: Research article

    The immune response during P. falciparum infection is a two-edged sword, involving dysregulation of the inflammatory responses with several types of immune cells participating. Here we examined T-cell, monocyte/m...

    Authors: Kari Otterdal, Aase Berg, Annika E. Michelsen, Sam Patel, Marit G. Tellevik, Christel G. Haanshuus, Børre Fevang, Pål Aukrust, Nina Langeland and Thor Ueland

    Citation: BMC Infectious Diseases 2018 18:670

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  27. Content type: Study protocol

    To combat emerging drug resistance in the Greater Mekong Sub-region (GMS) the World Health Organization and GMS countries have committed to eliminating malaria in the region by 2030. The overall approach inclu...

    Authors: Win Han Oo, Julia C. Cutts, Paul A. Agius, Kyaw Zayar Aung, Poe Poe Aung, Aung Thi, Nyi Nyi Zaw, Htin Kyaw Thu, Wai Yan Min Htay, Ricardo Ataide, Katherine O’Flaherty, Ai Pao Yawn, Aung Paing Soe, James G. Beeson, Brendan Crabb, Naanki Pasricha…

    Citation: BMC Infectious Diseases 2018 18:663

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  28. Content type: Study protocol

    Large scale administration of the anthelminthic drug praziquantel (PZQ) to at-risk populations is the cornerstone of schistosomiasis control, although persisting high prevalence of infections in some areas and...

    Authors: P. T. Hoekstra, M. Casacuberta Partal, A. S. Amoah, L. van Lieshout, P. L. A. M. Corstjens, S. Tsonaka, R. K. Assaré, K. D. Silué, A. Meité, E. K. N’Goran, Y. K. N’Gbesso, M. Roestenberg, S. Knopp, J. Utzinger, J. T. Coulibaly and G. J. van Dam

    Citation: BMC Infectious Diseases 2018 18:662

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  29. Content type: Research article

    About 80% of all reported sickle cell disease (SCD) cases in children anually are recorded in Africa. Although malaria is considered a major cause of death in SCD children, there is limited data on the safety ...

    Authors: Augustina Frimpong, Laty Gaye Thiam, Benjamin Arko-Boham, Ewurama Dedea Ampadu Owusu and George O. Adjei

    Citation: BMC Infectious Diseases 2018 18:650

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  30. Content type: Research article

    Malaria prevalence in Cameroon is a major public health problem both at the regional and urban-rural geographic scale. In 2016, an estimated 1.6 million confirmed cases, and 18,738 cases were reported in healt...

    Authors: Marlvin Anemey Tewara, Prisca Ngetemalah Mbah-Fongkimeh, Alimu Dayimu, Fengling Kang and Fuzhong Xue

    Citation: BMC Infectious Diseases 2018 18:636

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  31. Content type: Research article

    Leishmaniasis is a neglected and poorly reported parasitic infection transmitted by sand flies in tropical and subtropical regions. Knowledge about leishmaniasis has become important in non-endemic countries d...

    Authors: Hedvig Glans, Leif Dotevall, Sara Karlsson Söbirk, Anna Färnert and Maria Bradley

    Citation: BMC Infectious Diseases 2018 18:632

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  32. Content type: Research article

    Previous studies have suggested that Toxoplasma gondii (T. gondii) infection might be associated with fatty liver disease. However, the relationship between non-alcoholic fatty liver disease (NAFLD) and T. gondii

    Authors: Jiaofeng Huang, Haoyang Zhang, Shiying Liu, Mingfang Wang, Bo Wan, Bharat Velani, Yueyong Zhu and Su Lin

    Citation: BMC Infectious Diseases 2018 18:629

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  33. Content type: Case report

    Anisakid nematodes (Anisakis spp. or Pseudoterranova spp.) usually infect gastric or intestinal walls, while they rarely infect in extra-gastrointestinal sites of human body. Generally, Anisakis spp. larvae are h...

    Authors: Yasuhiro Murata, Katsuhiko Ando, Masanobu Usui, Hiromu Sugiyama, Akinobu Hayashi, Akihiro Tanemura, Hiroyuki Kato, Naohisa Kuriyama, Masashi Kishiwada, Shugo Mizuno, Hiroyuki Sakurai and Shuji Isaji

    Citation: BMC Infectious Diseases 2018 18:619

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  34. Content type: Research article

    In the Republic of Congo, artemisinin-based combinations have been recommended for the treatment of uncomplicated malaria since 2006. However, the emergence of resistant parasites again these combinations in S...

    Authors: Pembe Issamou Mayengue, Roch Fabien Niama, Dezi Kouhounina Batsimba, Alida Malonga-Massanga, Igor Louzolo, Nadia Claricelle Loukabou Bongolo, Lucette Macosso, Reyna Ibara Ottia, Ghyslain Kimbassa Ngoma, Louis Régis Dossou-Yovo, Brice Pembet Singana, Gabriel Ahombo, Géril Sekangue Obili, Simon Charles Kobawila and Henri Joseph Parra

    Citation: BMC Infectious Diseases 2018 18:538

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  35. Content type: Research article

    Vietnam is endemic for taeniasis and T. solium cysticercosis. Despite this, information on the epidemiological characteristics of the diseases in the Central Highlands of Vietnam are poorly described. The aims of...

    Authors: Dinh Ng-Nguyen, Mark Anthony Stevenson, Kathleen Breen, Trong Van Phan, Van-Anh Thi Nguyen, Tinh Van Vo and Rebecca Justine Traub

    Citation: BMC Infectious Diseases 2018 18:527

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  36. Content type: Research article

    Visceral leishmaniasis (VL), caused by Leishmania donovani complex parasites, is a neglected parasitic disease that is generally fatal if untreated. Despite decades of research to develop a sensitive VL diagnosti...

    Authors: Wen-Wei Zhang, Ayan Kumar Ghosh, Raodoh Mohamath, Jacqueline Whittle, Alessandro Picone, Patrick Lypaczewski, Momar Ndao, Randall F Howard, Pradeep Das, Steven G Reed and Greg Matlashewski

    Citation: BMC Infectious Diseases 2018 18:500

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  37. Content type: Case report

    Leishmaniasis is endemic in many countries worldwide, with a prevalence of 12 million people infected, and an estimated annual incidence of 500 000 visceral leishmaniasis cases. In Europe visceral leishmaniasi...

    Authors: Charlotte Adamczick, Alexa Dierig, Tatjana Welzel, Alexandra Schifferli, Johannes Blum and Nicole Ritz

    Citation: BMC Infectious Diseases 2018 18:495

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  38. Content type: Research article

    Tungiasis is an ectoparasitic infestation, which still has public health importance in deprived populations of developing countries. Data on the prevalence and risk factors of tungiasis is rare in Ethiopia. He...

    Authors: Mekonnen Girma, Ayalew Astatkie and Solomon Asnake

    Citation: BMC Infectious Diseases 2018 18:456

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  39. Content type: Research article

    Epidemiological information on the burden of various parasitic infections and associated factors in different localities is indispensable to develop appropriate control and prevention measures as well as to mo...

    Authors: Getaneh Alemu, Zeleke Aschalew and Eshetu Zerihun

    Citation: BMC Infectious Diseases 2018 18:435

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  40. Content type: Research article

    Genetic diversity in Plasmodium falciparum (P. falciparum) parasites is a major hurdle to the control of malaria. This study monitored changes in the genetic diversity and the multiplicity of P. falciparum parasi...

    Authors: Joshua Adjah, Bless Fiadzoe, Ruth Ayanful-Torgby and Linda E. Amoah

    Citation: BMC Infectious Diseases 2018 18:432

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  41. Content type: Research article

    Pet ownership in China has been steadily increasing over recent years. However, the risk of pet-associated zoonotic infection with the protozoan parasite Toxoplasma gondii remains poorly defined.

    Authors: Wei Cong, Hany M. Elsheikha, Na Zhou, Peng Peng, Si-Yuan Qin, Qing-Feng Meng and Ai-Dong Qian

    Citation: BMC Infectious Diseases 2018 18:430

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  42. Content type: Research article

    Toxoplasma gondii infection can be acquired through ingestion of infectious tissue cysts in undercooked meat or environmental oocysts excreted by cats. This cross-sectional study assessed environmental risk facto...

    Authors: Andrey I. Egorov, Reagan Converse, Shannon M. Griffin, Jennifer Styles, Elizabeth Klein, Elizabeth Sams, Edward Hudgens and Timothy J. Wade

    Citation: BMC Infectious Diseases 2018 18:421

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  43. Content type: Research article

    Malaria transmission is both seasonal and heterogeneous, and mathematical models that seek to predict the effects of possible intervention strategies should accurately capture realistic seasonality of vector a...

    Authors: Prashanth Selvaraj, Edward A. Wenger and Jaline Gerardin

    Citation: BMC Infectious Diseases 2018 18:413

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  44. Content type: Research article

    Over 80% of morbidity due to soil-transmitted helminthiasis (STH) occurs in low-income countries. Children under 5 account for 20–30% of the burden in endemic areas. This study assessed the prevalence, intensi...

    Authors: Silvestro Ojja, Stevens Kisaka, Michael Ediau, Doreen Tuhebwe, Angela N. Kisakye, Abdullah A. Halage, Richard K. Mugambe and Joan N. Mutyoba

    Citation: BMC Infectious Diseases 2018 18:408

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  45. Content type: Research article

    Schistosomiasis, caused by Schistosoma japonicum, remains one of the most important parasitic diseases, and detection of S. japonicum infections in humans plays a crucial role in control and treatment. However, c...

    Authors: Yao Deng, Chen Qiu, Huan Ding and Da-Bing Lu

    Citation: BMC Infectious Diseases 2018 18:404

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  46. Content type: Research article

    Monitoring of undernutrition and parasitic infection are essential to design appropriate intervention strategies. The aim of this study was to assess the prevalence of undernutrition, intestinal parasitic infe...

    Authors: Tamirat Hailegebriel

    Citation: BMC Infectious Diseases 2018 18:394

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  47. Content type: Research article

    The decline in the efficacy of artemisinin-based combination treatment (ACT) in some endemic regions threatens the progress towards global elimination of malaria. Molecular surveillance of drug resistance in m...

    Authors: Kolapo Muyiwa Oyebola, Oluwagbemiga Olanrewaju Aina, Emmanuel Taiwo Idowu, Yetunde Adeola Olukosi, Olusola Sunday Ajibaye, Olubunmi Adetoro Otubanjo, Taiwo Samson Awolola, Gordon Akanzuwine Awandare and Alfred Amambua-Ngwa

    Citation: BMC Infectious Diseases 2018 18:392

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  48. Content type: Research article

    Intestinal parasites are the most common infections in developing countries. Prevalence and impacts of these parasites are high in pregnant women. The aims of this study were to determine prevalence of helmint...

    Authors: Berhanu Elfu Feleke and Tadesse Hailu Jember

    Citation: BMC Infectious Diseases 2018 18:373

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  49. Content type: Case report

    Primary amoebic meningoencephalitis (PAM), caused by Naegleria fowleri, is a rare protozoan infectious disease in China. A fatality rate of over 95% had been reported due to extremely rapid disease progression in...

    Authors: Qiang Wang, Jianming Li, Jingkai Ji, Liuqing Yang, Li Chen, Rongrong Zhou, Yang Yang, Haixia Zheng, Jing Yuan, Liqiang Li, Yuhai Bi, George F. Gao, Jinmin Ma and Yingxia Liu

    Citation: BMC Infectious Diseases 2018 18:349

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  50. Content type: Research article

    Toxoplasma gondii is a protozoan parasite with worldwide distribution, infecting a broad-range of humans and warm-blooded animals. In the current study, role of this parasite on secondary sex ratio and risk of mi...

    Authors: Saeedeh Shojaee, Aref Teimouri, Hossein Keshavarz, Sanaz Jafarpour Azami and Sahar Nouri

    Citation: BMC Infectious Diseases 2018 18:307

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