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Parasitological diseases

Section edited by Honorine Ward & Laith Yakob 

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of parasitological diseases in humans, as well as related studies on molecular and cellular biology, pathophysiology, and epidemiology.

Page 1 of 7

  1. Content type: Case report

    Visceral leishmaniasis (VL) is becoming endemic in São Paulo state, in the southeastern region of Brazil. Unusual manifestations with non-specific signs and symptoms may make diagnosis difficult and delay trea...

    Authors: Luiz Euribel Prestes-Carneiro, Patricia Rodrigues Naufal Spir, Mateus Fontanesi, Karen Gabriella Pereira Garcia, Francisco Assis da Silva, Edilson Ferreira Flores and Dewton de Moraes Vasconcelos

    Citation: BMC Infectious Diseases 2019 19:70

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  2. Content type: Research article

    Human schistosomiases are acute and chronic infectious diseases of poverty. Currently, epidemiological data of urinary schistosomiasis (US) in school-age children (SAC) and adults are often reported together m...

    Authors: Tolulope Ebenezer Atalabi and Taiwo Oluwakemi Adubi

    Citation: BMC Infectious Diseases 2019 19:73

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  3. Content type: Case report

    Cystic echinococcosis (CE) is a worldwide zoonosis and the liver is the most commonly affected organ. Clinical manifestations range from completely asymptomatic cysts to a potential lethal cyst rupture and ana...

    Authors: Flaminia Coluzzi, Roberto Luca Meniconi, Damiano Caruso, Flaminia Rivosecchi, Linda Petrone, Delia Goletti and Giuseppe Maria Ettorre

    Citation: BMC Infectious Diseases 2019 19:37

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  4. Content type: Case report

    Hepatic clonorchiasis is one of the most prevalent food-borne parasitic diseases worldwide. Clonorchis sinensis, the pathogen, is the major parasitic trigger contributing to cholangitis, cholelithiasis, and even ...

    Authors: Xialei Liu, Genglong Zhu, Chaonong Cai, Zhiyue Lv and Jian Li

    Citation: BMC Infectious Diseases 2019 19:33

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  5. Content type: Research article

    Cutaneous leishmaniasis (CL) is a serious health problem in Suriname. To expand the diagnostic options, two newly developed diagnostic tests, i.e. the rapid diagnostic test CL Detect™ Rapid Test (CL Detect) an...

    Authors: Henk D. F. H. Schallig, Ricardo V. P. Hu, Alida D. Kent, Merlin van Loenen, Sandra Menting, Albert Picado, Zippora Oosterling and Israel Cruz

    Citation: BMC Infectious Diseases 2019 19:25

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  6. Content type: Research article

    Visceral leishmaniasis (VL) is a neglected tropical disease of public health relevance in Brazil. To prioritize disease control measures, the Secretaria de Vigilância em Saúde of Brazil’s Ministry of Health (S...

    Authors: Gustavo Machado, Julio Alvarez, Haakon Christopher Bakka, Andres Perez, Lucas Edel Donato, Francisco Edilson de Ferreira Lima Júnior, Renato Vieira Alves and Victor Javier Del Rio Vilas

    Citation: BMC Infectious Diseases 2019 19:2

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  7. Content type: Case report

    We report on a 21-year-old patient with a giant symptomatic hydatid cyst of the interventricular septum, to whom a staged management approach was employed. Induction medical therapy led to a reduction in the s...

    Authors: Jadranka Separovic Hanzevacki, Hrvoje Gasparovic, Vlatka Reskovic Luksic, Zvonimir Ostojic and Bojan Biocina

    Citation: BMC Infectious Diseases 2018 18:694

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  8. Content type: Research article

    The immune response during P. falciparum infection is a two-edged sword, involving dysregulation of the inflammatory responses with several types of immune cells participating. Here we examined T-cell, monocyte/m...

    Authors: Kari Otterdal, Aase Berg, Annika E. Michelsen, Sam Patel, Marit G. Tellevik, Christel G. Haanshuus, Børre Fevang, Pål Aukrust, Nina Langeland and Thor Ueland

    Citation: BMC Infectious Diseases 2018 18:670

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  9. Content type: Study protocol

    To combat emerging drug resistance in the Greater Mekong Sub-region (GMS) the World Health Organization and GMS countries have committed to eliminating malaria in the region by 2030. The overall approach inclu...

    Authors: Win Han Oo, Julia C. Cutts, Paul A. Agius, Kyaw Zayar Aung, Poe Poe Aung, Aung Thi, Nyi Nyi Zaw, Htin Kyaw Thu, Wai Yan Min Htay, Ricardo Ataide, Katherine O’Flaherty, Ai Pao Yawn, Aung Paing Soe, James G. Beeson, Brendan Crabb, Naanki Pasricha…

    Citation: BMC Infectious Diseases 2018 18:663

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  10. Content type: Study protocol

    Large scale administration of the anthelminthic drug praziquantel (PZQ) to at-risk populations is the cornerstone of schistosomiasis control, although persisting high prevalence of infections in some areas and...

    Authors: P. T. Hoekstra, M. Casacuberta Partal, A. S. Amoah, L. van Lieshout, P. L. A. M. Corstjens, S. Tsonaka, R. K. Assaré, K. D. Silué, A. Meité, E. K. N’Goran, Y. K. N’Gbesso, M. Roestenberg, S. Knopp, J. Utzinger, J. T. Coulibaly and G. J. van Dam

    Citation: BMC Infectious Diseases 2018 18:662

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  11. Content type: Research article

    About 80% of all reported sickle cell disease (SCD) cases in children anually are recorded in Africa. Although malaria is considered a major cause of death in SCD children, there is limited data on the safety ...

    Authors: Augustina Frimpong, Laty Gaye Thiam, Benjamin Arko-Boham, Ewurama Dedea Ampadu Owusu and George O. Adjei

    Citation: BMC Infectious Diseases 2018 18:650

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  12. Content type: Research article

    Malaria prevalence in Cameroon is a major public health problem both at the regional and urban-rural geographic scale. In 2016, an estimated 1.6 million confirmed cases, and 18,738 cases were reported in healt...

    Authors: Marlvin Anemey Tewara, Prisca Ngetemalah Mbah-Fongkimeh, Alimu Dayimu, Fengling Kang and Fuzhong Xue

    Citation: BMC Infectious Diseases 2018 18:636

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  13. Content type: Research article

    Leishmaniasis is a neglected and poorly reported parasitic infection transmitted by sand flies in tropical and subtropical regions. Knowledge about leishmaniasis has become important in non-endemic countries d...

    Authors: Hedvig Glans, Leif Dotevall, Sara Karlsson Söbirk, Anna Färnert and Maria Bradley

    Citation: BMC Infectious Diseases 2018 18:632

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  14. Content type: Research article

    Previous studies have suggested that Toxoplasma gondii (T. gondii) infection might be associated with fatty liver disease. However, the relationship between non-alcoholic fatty liver disease (NAFLD) and T. gondii

    Authors: Jiaofeng Huang, Haoyang Zhang, Shiying Liu, Mingfang Wang, Bo Wan, Bharat Velani, Yueyong Zhu and Su Lin

    Citation: BMC Infectious Diseases 2018 18:629

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  15. Content type: Case report

    Anisakid nematodes (Anisakis spp. or Pseudoterranova spp.) usually infect gastric or intestinal walls, while they rarely infect in extra-gastrointestinal sites of human body. Generally, Anisakis spp. larvae are h...

    Authors: Yasuhiro Murata, Katsuhiko Ando, Masanobu Usui, Hiromu Sugiyama, Akinobu Hayashi, Akihiro Tanemura, Hiroyuki Kato, Naohisa Kuriyama, Masashi Kishiwada, Shugo Mizuno, Hiroyuki Sakurai and Shuji Isaji

    Citation: BMC Infectious Diseases 2018 18:619

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  16. Content type: Research article

    In the Republic of Congo, artemisinin-based combinations have been recommended for the treatment of uncomplicated malaria since 2006. However, the emergence of resistant parasites again these combinations in S...

    Authors: Pembe Issamou Mayengue, Roch Fabien Niama, Dezi Kouhounina Batsimba, Alida Malonga-Massanga, Igor Louzolo, Nadia Claricelle Loukabou Bongolo, Lucette Macosso, Reyna Ibara Ottia, Ghyslain Kimbassa Ngoma, Louis Régis Dossou-Yovo, Brice Pembet Singana, Gabriel Ahombo, Géril Sekangue Obili, Simon Charles Kobawila and Henri Joseph Parra

    Citation: BMC Infectious Diseases 2018 18:538

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  17. Content type: Research article

    Vietnam is endemic for taeniasis and T. solium cysticercosis. Despite this, information on the epidemiological characteristics of the diseases in the Central Highlands of Vietnam are poorly described. The aims of...

    Authors: Dinh Ng-Nguyen, Mark Anthony Stevenson, Kathleen Breen, Trong Van Phan, Van-Anh Thi Nguyen, Tinh Van Vo and Rebecca Justine Traub

    Citation: BMC Infectious Diseases 2018 18:527

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  18. Content type: Research article

    Visceral leishmaniasis (VL), caused by Leishmania donovani complex parasites, is a neglected parasitic disease that is generally fatal if untreated. Despite decades of research to develop a sensitive VL diagnosti...

    Authors: Wen-Wei Zhang, Ayan Kumar Ghosh, Raodoh Mohamath, Jacqueline Whittle, Alessandro Picone, Patrick Lypaczewski, Momar Ndao, Randall F Howard, Pradeep Das, Steven G Reed and Greg Matlashewski

    Citation: BMC Infectious Diseases 2018 18:500

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  19. Content type: Case report

    Leishmaniasis is endemic in many countries worldwide, with a prevalence of 12 million people infected, and an estimated annual incidence of 500 000 visceral leishmaniasis cases. In Europe visceral leishmaniasi...

    Authors: Charlotte Adamczick, Alexa Dierig, Tatjana Welzel, Alexandra Schifferli, Johannes Blum and Nicole Ritz

    Citation: BMC Infectious Diseases 2018 18:495

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  20. Content type: Research article

    Tungiasis is an ectoparasitic infestation, which still has public health importance in deprived populations of developing countries. Data on the prevalence and risk factors of tungiasis is rare in Ethiopia. He...

    Authors: Mekonnen Girma, Ayalew Astatkie and Solomon Asnake

    Citation: BMC Infectious Diseases 2018 18:456

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  21. Content type: Research article

    Genetic diversity in Plasmodium falciparum (P. falciparum) parasites is a major hurdle to the control of malaria. This study monitored changes in the genetic diversity and the multiplicity of P. falciparum parasi...

    Authors: Joshua Adjah, Bless Fiadzoe, Ruth Ayanful-Torgby and Linda E. Amoah

    Citation: BMC Infectious Diseases 2018 18:432

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  22. Content type: Research article

    Pet ownership in China has been steadily increasing over recent years. However, the risk of pet-associated zoonotic infection with the protozoan parasite Toxoplasma gondii remains poorly defined.

    Authors: Wei Cong, Hany M. Elsheikha, Na Zhou, Peng Peng, Si-Yuan Qin, Qing-Feng Meng and Ai-Dong Qian

    Citation: BMC Infectious Diseases 2018 18:430

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  23. Content type: Research article

    Epidemiological information on the burden of various parasitic infections and associated factors in different localities is indispensable to develop appropriate control and prevention measures as well as to mo...

    Authors: Getaneh Alemu, Zeleke Aschalew and Eshetu Zerihun

    Citation: BMC Infectious Diseases 2018 18:435

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  24. Content type: Research article

    Toxoplasma gondii infection can be acquired through ingestion of infectious tissue cysts in undercooked meat or environmental oocysts excreted by cats. This cross-sectional study assessed environmental risk facto...

    Authors: Andrey I. Egorov, Reagan Converse, Shannon M. Griffin, Jennifer Styles, Elizabeth Klein, Elizabeth Sams, Edward Hudgens and Timothy J. Wade

    Citation: BMC Infectious Diseases 2018 18:421

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  25. Content type: Research article

    Malaria transmission is both seasonal and heterogeneous, and mathematical models that seek to predict the effects of possible intervention strategies should accurately capture realistic seasonality of vector a...

    Authors: Prashanth Selvaraj, Edward A. Wenger and Jaline Gerardin

    Citation: BMC Infectious Diseases 2018 18:413

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  26. Content type: Research article

    Over 80% of morbidity due to soil-transmitted helminthiasis (STH) occurs in low-income countries. Children under 5 account for 20–30% of the burden in endemic areas. This study assessed the prevalence, intensi...

    Authors: Silvestro Ojja, Stevens Kisaka, Michael Ediau, Doreen Tuhebwe, Angela N. Kisakye, Abdullah A. Halage, Richard K. Mugambe and Joan N. Mutyoba

    Citation: BMC Infectious Diseases 2018 18:408

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  27. Content type: Research article

    Schistosomiasis, caused by Schistosoma japonicum, remains one of the most important parasitic diseases, and detection of S. japonicum infections in humans plays a crucial role in control and treatment. However, c...

    Authors: Yao Deng, Chen Qiu, Huan Ding and Da-Bing Lu

    Citation: BMC Infectious Diseases 2018 18:404

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  28. Content type: Research article

    The decline in the efficacy of artemisinin-based combination treatment (ACT) in some endemic regions threatens the progress towards global elimination of malaria. Molecular surveillance of drug resistance in m...

    Authors: Kolapo Muyiwa Oyebola, Oluwagbemiga Olanrewaju Aina, Emmanuel Taiwo Idowu, Yetunde Adeola Olukosi, Olusola Sunday Ajibaye, Olubunmi Adetoro Otubanjo, Taiwo Samson Awolola, Gordon Akanzuwine Awandare and Alfred Amambua-Ngwa

    Citation: BMC Infectious Diseases 2018 18:392

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  29. Content type: Research article

    Monitoring of undernutrition and parasitic infection are essential to design appropriate intervention strategies. The aim of this study was to assess the prevalence of undernutrition, intestinal parasitic infe...

    Authors: Tamirat Hailegebriel

    Citation: BMC Infectious Diseases 2018 18:394

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  30. Content type: Research article

    Intestinal parasites are the most common infections in developing countries. Prevalence and impacts of these parasites are high in pregnant women. The aims of this study were to determine prevalence of helmint...

    Authors: Berhanu Elfu Feleke and Tadesse Hailu Jember

    Citation: BMC Infectious Diseases 2018 18:373

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  31. Content type: Case report

    Primary amoebic meningoencephalitis (PAM), caused by Naegleria fowleri, is a rare protozoan infectious disease in China. A fatality rate of over 95% had been reported due to extremely rapid disease progression in...

    Authors: Qiang Wang, Jianming Li, Jingkai Ji, Liuqing Yang, Li Chen, Rongrong Zhou, Yang Yang, Haixia Zheng, Jing Yuan, Liqiang Li, Yuhai Bi, George F. Gao, Jinmin Ma and Yingxia Liu

    Citation: BMC Infectious Diseases 2018 18:349

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  32. Content type: Research article

    Cystic echinococcosis (CE) is a well-known neglected parasitic disease. However, evidence supporting the four current treatment modalities is inadequate, and treatment options remain controversial. The aim of ...

    Authors: Virginia Velasco-Tirado, Montserrat Alonso-Sardón, Amparo Lopez-Bernus, Ángela Romero-Alegría, Francisco Javier Burguillo, Antonio Muro, Adela Carpio-Pérez, Juan Luis Muñoz Bellido, Javier Pardo-Lledias, Miguel Cordero and Moncef Belhassen-García

    Citation: BMC Infectious Diseases 2018 18:306

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  33. Content type: Research article

    Toxoplasma gondii is a protozoan parasite with worldwide distribution, infecting a broad-range of humans and warm-blooded animals. In the current study, role of this parasite on secondary sex ratio and risk of mi...

    Authors: Saeedeh Shojaee, Aref Teimouri, Hossein Keshavarz, Sanaz Jafarpour Azami and Sahar Nouri

    Citation: BMC Infectious Diseases 2018 18:307

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  34. Content type: Research article

    Schistosomiasis, a neglected tropical disease caused by parasites that infest open water sources such as rivers and dams may increase susceptibility to HIV. Mass-treatment with praziquantel tablets, recommende...

    Authors: Andrea Lothe, Nqobile Zulu, Arne Olav Øyhus, Eyrun Floerecke Kjetland and Myra Taylor

    Citation: BMC Infectious Diseases 2018 18:239

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  35. Content type: Research article

    Chagas disease (CD) is a systemic parasitic infection caused by the protozoan Trypanosoma cruzi, whose chronic phase may lead to cardiac and intestinal disorders. Endemic in Latin America where it is transmitted ...

    Authors: Stefania Pane, Maria Letizia Giancola, Pierluca Piselli, Angela Corpolongo, Ernestina Repetto, Rita Bellagamba, Claudia Cimaglia, Stefania Carrara, Piero Ghirga, Alessandra Oliva, Nazario Bevilacqua, Ahmad Al Rousan, Carla Nisii, Giuseppe Ippolito and Emanuele Nicastri

    Citation: BMC Infectious Diseases 2018 18:212

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  36. Content type: Research article

    The front line molecules from filarial worms and other nematodes or helminthes are their Excretory-Secretory (ES) products. Their interaction with the host cells, proteins and immune system accounts for the sk...

    Authors: Djafsia Boursou, Dieudonné Ndjonka, Albert Eisenbarth, Kingsley Manchang, Archille Paguem, Nancy Ngwafu Ngwasiri, Jacqueline Dikti Vildina, Babette Abanda, Ralf Krumkamp, Silke van Hoorn, Alfons Renz, Mbunkah Daniel Achukwi, Eva Liebau and Norbert W. Brattig

    Citation: BMC Infectious Diseases 2018 18:200

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  37. Content type: Case report

    Thailand is a major destination for German travellers with more than 760,000 arrivals in 2015. At the same time, malaria is a concern in travel recommendations with regard to this destination. The World Malari...

    Authors: Guenter Froeschl, Marcus Beissner, Kristina Huber, Gisela Bretzel, Michael Hoelscher and Camilla Rothe

    Citation: BMC Infectious Diseases 2018 18:148

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  38. Content type: Case report

    In immunocompetent patients, acute toxoplasmosis is usually asymptomatic. We identified M1 macrophages in a case of symptomatic acute Toxoplasma gondii infection that resolved without treatment. M1 macrophages ha...

    Authors: Graziano De Luca, Chiara Di Lisio, Giuseppe Lattanzio, Tommaso D’Antuono, Marcella Liberatore and Francesca Bianca Aiello

    Citation: BMC Infectious Diseases 2018 18:139

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  39. Content type: Research article

    Glucose-6-phosphate dehydrogenase (G6PD; EC deficiency is one of the most common X-linked recessive hereditary disorders in the world. Primaquine (PQ) has been used for radical cure of P. vivax to preve...

    Authors: Jinyoung Lee, Tae Im Kim, Jung-Mi Kang, Hojong Jun, Hương Giang Lê, Thị Lam Thái, Woon-Mok Sohn, Moe Kyaw Myint, Khin Lin, Tong-Soo Kim and Byoung-Kuk Na

    Citation: BMC Infectious Diseases 2018 18:131

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  40. Content type: Research article

    The zoonotic parasite Taenia solium is endemic in Angónia district, Tete province, Mozambique, though the burden of the disease complex is unknown.

    Authors: Chiara Trevisan, Brecht Devleesschauwer, Nicolas Praet, Alberto Pondja, Yunus Amade Assane, Pierre Dorny, Stig Milan Thamsborg, Pascal Magnussen and Maria Vang Johansen

    Citation: BMC Infectious Diseases 2018 18:127

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  41. Content type: Research article

    China has initiated the National Malaria Elimination Action Plan, which aims to eliminate malaria by 2020. However, the transmission of malaria occurs sporadically or in distinct foci, which greatly hampers pr...

    Authors: Jun Feng, Hong Tu, Li Zhang, Shaosen Zhang, Shan Jiang, Zhigui Xia and Shuisen Zhou

    Citation: BMC Infectious Diseases 2018 18:115

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  42. Content type: Research article

    Leishmaniasis, a vector borne tropical/subtropical disease caused by the protozoan Leishmania is transmitted to humans by sandfly vectors Phlebotomus and Lutzomyia. The principal form found in Sri Lanka is cutane...

    Authors: Devika Iddawela, Sanura Malinda Pallegoda Vithana, Dhilma Atapattu and Lanka Wijekoon

    Citation: BMC Infectious Diseases 2018 18:108

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  43. Content type: Case report

    Accurate and early diagnosis of neurocysticercosis (NCC) remains a challenge due to the heterogeneity of its clinical, immunological and imaging characteristics. The presence of cysticercus DNA in cerebrospina...

    Authors: Ping Liu, Xing Weng, Jiajia Zhou, Xiaolin Xu, Fangping He, Yue Du, Honglong Wu, Yanping Gong and Guoping Peng

    Citation: BMC Infectious Diseases 2018 18:113

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  44. Content type: Research article

    Schistosomiasis remains a global health problem with an estimated 250 million people in 78 countries infected, of whom 85% live in Sub-Saharan Africa. Preventive chemotherapy remains the key public health stra...

    Authors: Hlengiwe Sacolo, Moses Chimbari and Chester Kalinda

    Citation: BMC Infectious Diseases 2018 18:46

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  45. Content type: Research article

    Malaria is a major cause of morbidity and mortality. Treatment of malaria in a timely manner could avert deaths. Treatment ultimately relies on the rapid and accurate diagnosis. Fluorescence in situ hybridizat...

    Authors: Regina Kandie, Rachel Ochola and Kariuki Njaanake

    Citation: BMC Infectious Diseases 2018 18:22

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  46. Content type: Case report

    Hydatid disease is a worldwide zoonosis produced by the larval stage of cestodes of the Echinococcus genus. Hydatid disease primarily involves the liver and lungs. The brain is involved in less than 2% of cases. ...

    Authors: Shu Chen, Ning Li, Feifei Yang, Jiqin Wu, Yuekai Hu, Shenglei Yu, Qi Chen, Xuan Wang, Xinyu Wang, Yuanyuan Liu and Jianming Zheng

    Citation: BMC Infectious Diseases 2018 18:12

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  47. Content type: Research article

    The inefficiency of the current tachyzoite antigen-based serological assays for the serodiagnosis of Toxoplasma gondii infection mandates the need for acquirement of reliable and standard diagnostic reagents. Rec...

    Authors: Khalid Hajissa, Robaiza Zakaria, Rapeah Suppian and Zeehaida Mohamed

    Citation: BMC Infectious Diseases 2017 17:807

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  48. Content type: Research article

    Severe malaria is a medical emergency associated with high mortality. Adequate treatment requires initial parenteral therapy for fast parasite clearance followed by longer acting oral antimalarial drugs for cu...

    Authors: Pauline Byakika-Kibwika, Jane Achan, Mohammed Lamorde, Carine Karera-Gonahasa, Agnes N. Kiragga, Harriet Mayanja-Kizza, Noah Kiwanuka, Sam Nsobya, Ambrose O. Talisuna and Concepta Merry

    Citation: BMC Infectious Diseases 2017 17:794

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  49. Content type: Research article

    Leishmania donovani is the etiological agent of visceral leishmaniasis (VL) in the Indian subcontinent. However, it is also known to cause cutaneous leishmaniasis (CL) in Sri Lanka. Sr...

    Authors: Udeshika Lakmini Kariyawasam, Angamuthu Selvapandiyan, Keshav Rai, Tasaduq Hussain Wani, Kavita Ahuja, Mizra Adil Beg, Hasitha Upendra Premathilake, Narayan Raj Bhattarai, Yamuna Deepani Siriwardena, Daibin Zhong, Guofa Zhou, Suman Rijal, Hira Nakhasi and Nadira D. Karunaweera

    Citation: BMC Infectious Diseases 2017 17:791

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  50. Content type: Case report

    Alice in Wonderland” syndrome (AIWS) is a rare neurological abnormality characterized by distortions of visual perceptions, body schema and experience of time. AIWS has been reported ...

    Authors: Benjamin Momo Kadia, Cyril Jabea Ekabe and Ettamba Agborndip

    Citation: BMC Infectious Diseases 2017 17:789

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