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Parasitological diseases

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of parasitological diseases in humans, as well as related studies on molecular and cellular biology, pathophysiology, and epidemiology.

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  1. The highly complex and largely neglected Chagas disease (CD) has become a global health problem due to population movements between Latin America and non-endemic countries, as well as non-vectorial transmissio...

    Authors: Jessica Michelle Guggenbühl Noller, Guenter Froeschl, Philip Eisermann, Johannes Jochum, Stefanie Theuring, Ingrid Reiter-Owona, Alfred Lennart Bissinger, Michael Hoelscher, Abhishek Bakuli, Franz-Josef Falkner von Sonnenburg, Camilla Rothe, Gisela Bretzel, Pedro Albajar-Viñas, Lise Grout and Michael Pritsch

    Citation: BMC Infectious Diseases 2020 20:919

    Content type: Research article

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  2. Primary infection with Toxoplasma gondii during pregnancy can pose serious health problems for the fetus. However, the epidemiological status of toxoplasmosis among reproductive-aged population in Myanmar is larg...

    Authors: Khin Myo Aye, Eiji Nagayasu, Myat Htut Nyunt, Ni Ni Zaw, Kyaw Zin Thant, Myat Phone Kyaw and Haruhiko Maruyama

    Citation: BMC Infectious Diseases 2020 20:906

    Content type: Research article

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  3. Sickle cell disease (SCD) is a monogenic disorder due to point mutation in the β-globin gene resulting in substitution of Valine for Glutamic acid. The SCD is prevalent in P. falciparum endemic regions such as we...

    Authors: Paul Kosiyo, Walter Otieno, Jesse Gitaka, Elly O. Munde and Collins Ouma

    Citation: BMC Infectious Diseases 2020 20:887

    Content type: Research article

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  4. World Health Organization estimated that 779 million people are at risk of getting schistosomiasis (SCH) and 240 million people were infected worldwide. SCH due to Schistosoma mansoni (S. mansoni) is a wide publi...

    Authors: Yilma Chisha, Zerihun Zerdo, Mekuria Asnakew, Chuchu Churko, Manaye Yihune, Abinet Teshome, Nebiyu Nigussu, Fikire Seife, Birhanu Getachew and Markos Sileshi

    Citation: BMC Infectious Diseases 2020 20:872

    Content type: Research article

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  5. Studies have shown that liver fluke infections may be associated with kidney injury and that Helicobacter pylori (Hp) may be involved in the pathogenesis of kidney diseases. However, no studies have reported the ...

    Authors: Weining Xie, Yuanjun Deng, Shengxin Chen, Yifeng Wu, Ye Li and Qinhe Yang

    Citation: BMC Infectious Diseases 2020 20:868

    Content type: Research article

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  6. Micronutrients are minerals and vitamins and they are essential for normal physiological activities. The objectives of the study were to describe the progress and determinants of micronutrient levels and to as...

    Authors: Berhanu Elfu Feleke and Teferi Elfu Feleke

    Citation: BMC Infectious Diseases 2020 20:867

    Content type: Research article

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  7. Light microscopy is often used for malaria diagnosis in the field. However, it is time-consuming and quality of the results depends heavily on the skill of microscopists. Automating malaria light microscopy is...

    Authors: Hang Yu, Feng Yang, Sivaramakrishnan Rajaraman, Ilker Ersoy, Golnaz Moallem, Mahdieh Poostchi, Kannappan Palaniappan, Sameer Antani, Richard J. Maude and Stefan Jaeger

    Citation: BMC Infectious Diseases 2020 20:825

    Content type: Software

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  8. Soil-transmitted helminths are more prevalent in tropics and sub-tropics including Ethiopia. Despite their high prevalence, direct saline microscopy with its low sensitivity has been used as a diagnostic metho...

    Authors: Abebe Fenta, Tadesse Hailu, Megbaru Alemu, Endalkachew Nibret, Arancha Amor and Abaineh Munshea

    Citation: BMC Infectious Diseases 2020 20:803

    Content type: Research article

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  9. Malaria infection during pregnancy has negative health consequences for both mothers and offspring. Sub-microscopic malaria infection during pregnancy is common in most African countries. We sought to identify...

    Authors: Aneth Vedastus Kalinjuma, Anne Marie Darling, Ferdinand M. Mugusi, Ajibola Ibraheem Abioye, Fredros O. Okumu, Said Aboud, Honorati Masanja, Davidson H. Hamer, Ellen Hertzmark and Wafaie W. Fawzi

    Citation: BMC Infectious Diseases 2020 20:796

    Content type: Research article

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  10. Pulmonary hemorrhage is an important complication of leptospirosis. Once acute respiratory distress syndrome (ARDS) occurs as a secondary condition, treatment is extremely difficult and the mortality rate is v...

    Authors: H. J. Wang, G. Z. Chen, C. J. Zhou, Y. FU and L. N. YAO

    Citation: BMC Infectious Diseases 2020 20:794

    Content type: Case report

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  11. Individuals that work and sleep in remote forest and farm locations in the Greater Mekong Subregion continue to remain at high risk of both acquiring and transmitting malaria. These difficult-to-access populat...

    Authors: Sara E. Canavati, Gerard C. Kelly, Cesia E. Quintero, Thuan Huu Vo, Long Khanh Tran, Thang Duc Ngo, Duong Thanh Tran, Kimberly A. Edgel and Nicholas J. Martin

    Citation: BMC Infectious Diseases 2020 20:757

    Content type: Research article

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  12. Chagas disease is a zoonotic infection caused by the parasite Trypanosoma cruzi, which affects an estimated 8–11 million people globally. Chagas disease is almost always associated with poverty in rural areas and...

    Authors: Paula Stigler Granados, Gerardo J. Pacheco, Evangelina Núñez Patlán, Jose Betancourt and Lawrence Fulton

    Citation: BMC Infectious Diseases 2020 20:743

    Content type: Research article

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  13. Ivermectin is an excellent microfilaricide against Onchocerca volvulus. However, in some regions, long term use of ivermectin has resulted in sub-optimal responses to the treatment. More data to properly document...

    Authors: Raphael Awah Abong, Glory N. Amambo, Patrick W. Chounna Ndongmo, Abdel Jelil Njouendou, Ritter Manuel, Amuam Andrew Beng, Mathias Eyong Esum, Kebede Deribe, Jerome Fru-Cho, Fanny F. Fombad, Theobald Mue Nji, Peter Ivo Enyong, Catherine B. Poole, Kenneth Pfarr, Achim Hoerauf, Clotilde K. S. Carlow…

    Citation: BMC Infectious Diseases 2020 20:726

    Content type: Research article

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  14. Spinal neuroschistosomiasis (SN) is one of the most severe clinical presentations of schistosomiasis infection and an ectopic form of the disease caused by any species of Schistosoma. In Brazil, all cases of this...

    Authors: Ana Lúcia Coutinho Domingues, Constança Simões Barbosa, Thiago Frederico Andrade Agt, Andréia Braga Mota, Clélia Maria Ribeiro Franco, Edmundo Pessoa Lopes, Rodrigo Loyo and Elainne Christine Souza Gomes

    Citation: BMC Infectious Diseases 2020 20:724

    Content type: Case report

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  15. Schistosoma antigen detection in urine is a valuable diagnostic approach for schistosomiasis control programmes because of the higher sensitivity compared to parasitological methods and preferred sampling of urin...

    Authors: Yabo Josiane Honkpehedji, Ayôla Akim Adegnika, Jean Claude Dejon-Agobe, Jeannot Fréjus Zinsou, Romuald Beh Mba, Jacob Gerstenberg, Raphaël Rakotozandrindrainy, Rivo Andry Rakotoarivelo, Tahinamandranto Rasamoelina, Elisa Sicuri, Norbert G. Schwarz, Paul L. A. M. Corstjens, Pytsje T. Hoekstra, Govert J. van Dam and Andrea Kreidenweiss

    Citation: BMC Infectious Diseases 2020 20:718

    Content type: Study protocol

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  16. Toxoplasma gondii infection endangers human health and affects animal husbandry. Serological detection is the main method used for epidemiological investigations and diagnosis of toxoplasmosis. The key to effecti...

    Authors: Zhuan-zhuan Liu, Xue-yan Li, Lin-lin Fu, Fei Yuan, Ren-xian Tang, Yi-sheng Liu and Kui-yang Zheng

    Citation: BMC Infectious Diseases 2020 20:694

    Content type: Research article

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  17. The incidence of angiostrongyliasis is increasing in recent decades due to the expanding endemic areas all over the world. Clinicians face tremendous challenge of diagnosing angiostrongyliasis because of the l...

    Authors: Li Feng, Aiwu Zhang, Jiali Que, Hongyan Zhou, Haiyan Wang, Yuanlin Guan, Cunzhou Shen, Xunsha Sun, Rong Lai, Fuhua Peng, Huiyu Feng and Ling Chen

    Citation: BMC Infectious Diseases 2020 20:691

    Content type: Case report

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  18. The increasing antimalarial drug resistance is a significant hindrance to malaria control and elimination programs. For the last six decades, chloroquine (CQ) plus pyrimethamine remains the first-line treatmen...

    Authors: Hargobinder Kaur, Rakesh Sehgal, Archit Kumar, Praveen K. Bharti, Devendra Bansal, Pradyumna K. Mohapatra, Jagadish Mahanta and Ali A. Sultan

    Citation: BMC Infectious Diseases 2020 20:671

    Content type: Research article

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  19. The parasite Entamoeba histolytica is the causal agent of amoebiasis, a worldwide emerging disease. Amebic brain abscess is a form of invasive amebiasis that is both rare and frequently lethal. This condition alw...

    Authors: Joaquin Alvaro Victoria-Hernández, Anayansi Ventura-Saucedo, Aurelio López-Morones, Sandra Luz Martínez-Hernández, Marina Nayeli Medina-Rosales, Martín Muñoz-Ortega, Manuel Enrique Ávila-Blanco, Daniel Cervantes-García, Luis Fernando Barba-Gallardo and Javier Ventura-Juárez

    Citation: BMC Infectious Diseases 2020 20:669

    Content type: Case report

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  20. Brucellosis is a zoonotic disease caused by brucella. It has been an increasing trend in recent years (Wang H, Xu WM, Zhu KJ, Zhu SJ, Zhang HF, Wang J, Yang Y, Shao FY, Jiang NM, Tao ZY, Jin HY, Tang Y, Huo LL...

    Authors: Lingling Geng, Yuan Feng, Dan Li, Nan Nan, Kai Ma, Xianyan Tang and Xiaoqing Li

    Citation: BMC Infectious Diseases 2020 20:654

    Content type: Case report

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  21. During the outbreak of cutaneous leishmaniasis in the Kurdistan Region of Iraq that started in 2015, the course of the disease and the treatment were not consistent with the available literature. Physicians, p...

    Authors: Dindar S. Qurtas and Nazar Pauls Shabila

    Citation: BMC Infectious Diseases 2020 20:645

    Content type: Research article

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  22. Malaria during pregnancy leads to serious adverse effects on mothers and the fetus. Approximately 25 million pregnant women in sub-Saharan Africa live at risk of malaria. This study would help to achieve Susta...

    Authors: Girma Bekele Gontie, Haileab Fekadu Wolde and Adhanom Gebreegziabher Baraki

    Citation: BMC Infectious Diseases 2020 20:573

    Content type: Research article

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  23. Plasmodium falciparum parasites, which could harbour anti-malaria drug resistance genes, are commonly detected in blood donors in malaria-endemic areas. Notwithstanding, anti-malaria drug resistant biomarkers hav...

    Authors: Enoch Aninagyei, Kwabena Obeng Duedu, Tanko Rufai, Comfort Dede Tetteh, Margaretta Gloria Chandi, Paulina Ampomah and Desmond Omane Acheampong

    Citation: BMC Infectious Diseases 2020 20:533

    Content type: Research article

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  24. Plasmodium falciparum dihydrofolate reductase (Pfdhfr) and dihydropteroate synthetase (Pfdhps) mutations compromise the effectiveness of sulfadoxine-pyrimethamine (SP) for treatment of uncomplicated malaria, and ...

    Authors: George M. Bwire, Wigilya P. Mikomangwa and Manase Kilonzi

    Citation: BMC Infectious Diseases 2020 20:530

    Content type: Research article

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  25. Dirofilariasis is a zoonotic parasitic infection transmitted from animals to humans by culicid mosquitoes. Although the disease can be caused by Dirofilaria spp. including Dirofilaria immitis and Dirofilaria repe...

    Authors: Razieh Parsa, Ali Sedighi, Iraj Sharifi, Mehdi Bamorovat and Saeid Nasibi

    Citation: BMC Infectious Diseases 2020 20:520

    Content type: Case report

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  26. Imported falciparum malaria from Africa has become a key public health challenge in Guizhou Province since 2012. Understanding the polymorphisms of molecular markers of drug resistance can guide selection of a...

    Authors: Danya She, Zhengyan Wang, Qiuguo Liang, Lidan Lu, Yuting Huang, Ke Zhang, Dong An and Jiahong Wu

    Citation: BMC Infectious Diseases 2020 20:513

    Content type: Research article

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  27. Understanding the relationship between malaria infection risk and disease outcomes represents a fundamental component of morbidity and mortality burden estimations. Contemporary data on severe malaria risks am...

    Authors: Arthur Mpimbaza, Richard Walemwa, James Kapisi, Asadu Sserwanga, Jane Frances Namuganga, Yasin Kisambira, Abner Tagoola, Jane Frances Nanteza, Damain Rutazaana, Sarah G. Staedke, Grant Dorsey, Jimmy Opigo, Alice Kamau and Robert W. Snow

    Citation: BMC Infectious Diseases 2020 20:503

    Content type: Research article

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  28. Genetic diversity of ABO blood, glucose-6-phosphate dehydrogenase (G6PD) deficiency and haemoglobin type and their ability to protect against malaria vary geographically, ethnically and racially. No study has ...

    Authors: Jafaralli Sande Ahmed, Bernard Guyah, David Sang’, Mark Kilongosi Webale, Nathan Shaviya Mufyongo, Elly Munde and Collins Ouma

    Citation: BMC Infectious Diseases 2020 20:487

    Content type: Research article

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  29. Strongyloidiasis is a gastrointestinal parasitic infection caused by percutaneous infection with Strongyloides stercoralis. Digestive symptoms such as diarrhea and abdominal pain are the main manifestation, but s...

    Authors: Chisato Ashida, Koji Kinoshita, Yuji Nozaki and Masanori Funauchi

    Citation: BMC Infectious Diseases 2020 20:470

    Content type: Case report

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  30. Why human tick-borne encephalitis (TBE) cases differ from year to year, in some years more 100%, has not been clarified, yet. The cause of the increasing or decreasing trends is also controversial. Austria is ...

    Authors: Franz Rubel, Melanie Walter, Janna R. Vogelgesang and Katharina Brugger

    Citation: BMC Infectious Diseases 2020 20:448

    Content type: Research article

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  31. Cerebral malaria is the most severe form of infection with Plasmodium falciparum characterized by a highly inflammatory response. This systematic review aimed to investigate the association between TNF-α levels a...

    Authors: Luana Leão, Bruna Puty, Maria Fâni Dolabela, Marinete Marins Povoa, Yago Gecy De Sousa Né, Luciana Guimarães Eiró, Nathália Carolina Fernandes Fagundes, Lucianne Cople Maia and Rafael Rodrigues Lima

    Citation: BMC Infectious Diseases 2020 20:442

    Content type: Research article

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  32. Malaria remains a major tropical vector-borne disease of immense public health concern owing to its debilitating effects in sub-Saharan Africa. Over the past 30 years, the high altitude areas in Eastern Africa...

    Authors: Aggrey Siya, Bosco John Kalule, Benard Ssentongo, Akim Tafadzwa Lukwa and Anthony Egeru

    Citation: BMC Infectious Diseases 2020 20:425

    Content type: Research article

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  33. In malaria endemic areas, identifying spatio-temporal hotspots is becoming an important element of innovative control strategies targeting transmission bottlenecks. The aim of this work was to describe the spa...

    Authors: Sokhna Dieng, El Hadj Ba, Badara Cissé, Kankoe Sallah, Abdoulaye Guindo, Boukary Ouedraogo, Martine Piarroux, Stanislas Rebaudet, Renaud Piarroux, Jordi Landier, Cheikh Sokhna and Jean Gaudart

    Citation: BMC Infectious Diseases 2020 20:424

    Content type: Research article

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  34. Mounting evidence suggested a complex correlation between host lipid metabolism and Toxoplasma gondii (T. gondii) infection. However, the inherent association between T. gondii infection and host lipid state rema...

    Authors: Fei Xu, Xiwan Lu, Ruitang Cheng, Yuwei Zhu, Sunhan Miao, Qinyi Huang, Yongliang Xu, Liying Qiu and Yonghua Zhou

    Citation: BMC Infectious Diseases 2020 20:415

    Content type: Research article

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  35. Alveolar echinococcosis (AE) is a zoonotic parasitic disease caused by Echinococcus multilocularis larval tapeworm infections in humans that severely impairs the health of affected patients in the northern hemisp...

    Authors: Xiao Ma, Xuefei Zhang, Jia Liu, Yufang Liu, Cunzhe Zhao, Huixia Cai, Wen Lei, Junying Ma, Haining Fan, Jianye Zhou, Na Liu, Jingxiao Zhang, Yongshun Wang, Wei Wang, Peizhen Zhan, Xiongying Zhang…

    Citation: BMC Infectious Diseases 2020 20:414

    Content type: Research article

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  36. Successful control programs have impeded local malaria transmission in almost all Gulf Cooperation Council (GCC) countries: Qatar, Bahrain, Kuwait, Oman, the United Arab Emirates (UAE) and Saudi Arabia. Nevert...

    Authors: Abir Al-Rumhi, Zainab Al-Hashami, Salama Al-Hamidhi, Amal Gadalla, Raeece Naeem, Lisa Ranford-Cartwright, Arnab Pain, Ali A. Sultan and Hamza A. Babiker

    Citation: BMC Infectious Diseases 2020 20:413

    Content type: Research article

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  37. Visceral leishmaniasis is an important but neglected disease that is spreading and is highly lethal when left untreated. This study sought to measure the Leishmania infantum seroprevalence in dogs, the coverage o...

    Authors: Patricia Marques Moralejo Bermudi, Danielle Nunes Carneiro Castro Costa, Caris Maroni Nunes, Jose Eduardo Tolezano, Roberto Mitsuyoshi Hiramoto, Lilian Aparecida Colebrusco Rodas, Rafael Silva Cipriano, Marta Blangiardo and Francisco Chiaravalloti-Neto

    Citation: BMC Infectious Diseases 2020 20:401

    Content type: Research article

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  38. Scabies is an infectious disease that affects the skin caused by the mite Sarcoptes scabiei and it transmitted through close personal contact. Even though it is easily treatable disease, its prevalence is high an...

    Authors: Abebaw Gedef Azene, Abiba Mihret Aragaw and Gizachew Tadesse Wassie

    Citation: BMC Infectious Diseases 2020 20:380

    Content type: Research article

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  39. Intestinal parasitic infections (IPIs) and anaemia are major health problems. This study assessed the prevalence of intestinal parasitic infections, anaemia and associated factors among pre-school children in ...

    Authors: Araya Gebreyesus Wasihun, Mekonen Teferi, Letemichal Negash, Javier Marugán, Dejen Yemane, Kevin G. McGuigan, Ronan M. Conroy, Haftu Temesgen Abebe and Tsehaye Asmelash Dejene

    Citation: BMC Infectious Diseases 2020 20:379

    Content type: Research article

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  40. Despite the existence of a population-based control program using single dose albendazole or mebendazole as a preventive chemotherapy, hookworm transmission remains high. It causes a negative impact on the gro...

    Authors: Tegegne Eshetu, Mulugeta Aemero and Ayalew Jejaw Zeleke

    Citation: BMC Infectious Diseases 2020 20:376

    Content type: Research article

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  41. Plasmodium vivax rarely develops severe complications when compared to severe falciparum malaria. However, severe vivax malaria also needs urgent, intensive care and treatment as severe falciparum malaria. This s...

    Authors: Manas Kotepui, Kwuntida Uthaisar Kotepui, Giovanni De Jesus Milanez and Frederick Ramirez Masangkay

    Citation: BMC Infectious Diseases 2020 20:363

    Content type: Research article

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  42. Microscopic examination of peripheral blood smear produces reliable results both about the malaria infection status and level of parasitemia. However, test results are affected by skill of the laboratory perso...

    Authors: Banchamlak Tegegne, Kefale Ejigu, Getaneh Alemu, Yeshimebet Fetene, Kindye Endaylalu and Mulatu Melese

    Citation: BMC Infectious Diseases 2020 20:355

    Content type: Research article

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  43. Pediatric diarrhea caused by a range of pathogens, including intestinal parasites, is one of main causes of death among children under 5 years of age. The distribution of these parasitic infections overlaps in...

    Authors: Sandrine Lydie Oyegue-Liabagui, Nal Kennedy Ndjangangoye, Lady Charlene Kouna, Gwladys Mirlande Lekolo, Franck Mounioko, Sylvie Kwedi Nolna and Jean Bernard Lekana-Douki

    Citation: BMC Infectious Diseases 2020 20:350

    Content type: Research article

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  44. Besides the considerable role of blackflies to the transmission of many disease agents, these flies considered as annoying biting pests of wildlife, livestock, poultry, and humans. There are few literature rep...

    Authors: Farbod Tabatabaei, Sahar Azarmi, Mohammad Javad Abbaszadeh Afshar, Hamed Yarizadeh and Sina Mohtasebi

    Citation: BMC Infectious Diseases 2020 20:348

    Content type: Case report

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  45. Enterobius vermicularis is an intestinal helminthic parasite that causes a gastrointestinal infection called enterobiasis. Children are more susceptible to infection than adults. The current study aimed to explor...

    Authors: Ahmed Akil Khudhair Al-Daoody and Eman Najdy Haydar Al-Bazzaz

    Citation: BMC Infectious Diseases 2020 20:336

    Content type: Research article

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  46. Malaria is a life threating vector borne disease caused by different Plasmodium parasites. Metema and Armachiho are two of the top five malaria endemic areas among the districts of Amhara region in Ethiopia. Tran...

    Authors: Yibeltal Aschale, Animen Ayehu, Ligabaw Worku, Ayenew Addisu, Ayalew Jejaw Zeleke, Abebe Genetu Bayih and Wossenseged Lemma

    Citation: BMC Infectious Diseases 2020 20:333

    Content type: Research article

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  47. Praziquantel (PZQ) is the standard treatment for Schistosomiasis in sub-Saharan Africa. However, there is evidence suggesting praziquantel treatment failure in Schistosome infections with associated potential ...

    Authors: Samuel Nkansah Darko, Henry Hanson, Sampson Twumasi-Ankrah, Sandra Baffour-Awuah, Priscilla Adjei-Kusi, Denis Yar and Ellis Owusu-Dabo

    Citation: BMC Infectious Diseases 2020 20:323

    Content type: Research article

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  48. Scrub typhus can present with atypical signs and symptoms such as those of acute kidney injury, gastroenteritis, pneumonitis, and acute respiratory distress syndrome. Meningitis, encephalitis, and hepatic dysf...

    Authors: Tulsi Bhattarai, Sujan Chandra Poudel, Nishma Pokharel and Suraj Bhattarai

    Citation: BMC Infectious Diseases 2020 20:322

    Content type: Case report

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  49. Trichomoniasis resulting from Trichomonas vaginalis (T. vaginalis) has been considered as a commonly seen disease with the transmission way of sex. At present, the detection methods of T. vaginalis mainly include...

    Authors: Yuhua Li, Shuai Wang, Haoran Li, Xiaoxiao Song, Hao Zhang, Yujuan Duan, Chengyang Luo, Bingli Wang, Sifan Ji, Qing Xie and Zhenchao Zhang

    Citation: BMC Infectious Diseases 2020 20:319

    Content type: Research article

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  50. Plasmodium vivax is the most widely distributed malaria parasite, and its drug resistance poses unique challenges to malaria elimination. The Greater Mekong Subregion (GMS) is known as the global epicenter of mul...

    Authors: Xiaoxiao Wang, Wei Ruan, Shuisen Zhou, Xinyu Feng, He Yan and Fang Huang

    Citation: BMC Infectious Diseases 2020 20:307

    Content type: Research article

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