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Parasitological diseases

Section edited by Honorine Ward & Laith Yakob 

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of parasitological diseases in humans, as well as related studies on molecular and cellular biology, pathophysiology, and epidemiology.

Page 1 of 6

  1. Content type: Research article

    Visceral leishmaniasis (VL), caused by Leishmania donovani complex parasites, is a neglected parasitic disease that is generally fatal if untreated. Despite decades of research to develop a sensitive VL diagnosti...

    Authors: Wen-Wei Zhang, Ayan Kumar Ghosh, Raodoh Mohamath, Jacqueline Whittle, Alessandro Picone, Patrick Lypaczewski, Momar Ndao, Randall F Howard, Pradeep Das, Steven G Reed and Greg Matlashewski

    Citation: BMC Infectious Diseases 2018 18:500

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  2. Content type: Case report

    Leishmaniasis is endemic in many countries worldwide, with a prevalence of 12 million people infected, and an estimated annual incidence of 500 000 visceral leishmaniasis cases. In Europe visceral leishmaniasi...

    Authors: Charlotte Adamczick, Alexa Dierig, Tatjana Welzel, Alexandra Schifferli, Johannes Blum and Nicole Ritz

    Citation: BMC Infectious Diseases 2018 18:495

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  3. Content type: Research article

    Tungiasis is an ectoparasitic infestation, which still has public health importance in deprived populations of developing countries. Data on the prevalence and risk factors of tungiasis is rare in Ethiopia. He...

    Authors: Mekonnen Girma, Ayalew Astatkie and Solomon Asnake

    Citation: BMC Infectious Diseases 2018 18:456

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  4. Content type: Research article

    Genetic diversity in Plasmodium falciparum (P. falciparum) parasites is a major hurdle to the control of malaria. This study monitored changes in the genetic diversity and the multiplicity of P. falciparum parasi...

    Authors: Joshua Adjah, Bless Fiadzoe, Ruth Ayanful-Torgby and Linda E. Amoah

    Citation: BMC Infectious Diseases 2018 18:432

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  5. Content type: Research article

    Pet ownership in China has been steadily increasing over recent years. However, the risk of pet-associated zoonotic infection with the protozoan parasite Toxoplasma gondii remains poorly defined.

    Authors: Wei Cong, Hany M. Elsheikha, Na Zhou, Peng Peng, Si-Yuan Qin, Qing-Feng Meng and Ai-Dong Qian

    Citation: BMC Infectious Diseases 2018 18:430

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  6. Content type: Research article

    Epidemiological information on the burden of various parasitic infections and associated factors in different localities is indispensable to develop appropriate control and prevention measures as well as to mo...

    Authors: Getaneh Alemu, Zeleke Aschalew and Eshetu Zerihun

    Citation: BMC Infectious Diseases 2018 18:435

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  7. Content type: Research article

    Toxoplasma gondii infection can be acquired through ingestion of infectious tissue cysts in undercooked meat or environmental oocysts excreted by cats. This cross-sectional study assessed environmental risk facto...

    Authors: Andrey I. Egorov, Reagan Converse, Shannon M. Griffin, Jennifer Styles, Elizabeth Klein, Elizabeth Sams, Edward Hudgens and Timothy J. Wade

    Citation: BMC Infectious Diseases 2018 18:421

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  8. Content type: Research article

    Malaria transmission is both seasonal and heterogeneous, and mathematical models that seek to predict the effects of possible intervention strategies should accurately capture realistic seasonality of vector a...

    Authors: Prashanth Selvaraj, Edward A. Wenger and Jaline Gerardin

    Citation: BMC Infectious Diseases 2018 18:413

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  9. Content type: Research article

    Over 80% of morbidity due to soil-transmitted helminthiasis (STH) occurs in low-income countries. Children under 5 account for 20–30% of the burden in endemic areas. This study assessed the prevalence, intensi...

    Authors: Silvestro Ojja, Stevens Kisaka, Michael Ediau, Doreen Tuhebwe, Angela N. Kisakye, Abdullah A. Halage, Richard K. Mugambe and Joan N. Mutyoba

    Citation: BMC Infectious Diseases 2018 18:408

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  10. Content type: Research article

    Schistosomiasis, caused by Schistosoma japonicum, remains one of the most important parasitic diseases, and detection of S. japonicum infections in humans plays a crucial role in control and treatment. However, c...

    Authors: Yao Deng, Chen Qiu, Huan Ding and Da-Bing Lu

    Citation: BMC Infectious Diseases 2018 18:404

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  11. Content type: Research article

    The decline in the efficacy of artemisinin-based combination treatment (ACT) in some endemic regions threatens the progress towards global elimination of malaria. Molecular surveillance of drug resistance in m...

    Authors: Kolapo Muyiwa Oyebola, Oluwagbemiga Olanrewaju Aina, Emmanuel Taiwo Idowu, Yetunde Adeola Olukosi, Olusola Sunday Ajibaye, Olubunmi Adetoro Otubanjo, Taiwo Samson Awolola, Gordon Akanzuwine Awandare and Alfred Amambua-Ngwa

    Citation: BMC Infectious Diseases 2018 18:392

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  12. Content type: Research article

    Monitoring of undernutrition and parasitic infection are essential to design appropriate intervention strategies. The aim of this study was to assess the prevalence of undernutrition, intestinal parasitic infe...

    Authors: Tamirat Hailegebriel

    Citation: BMC Infectious Diseases 2018 18:394

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  13. Content type: Research article

    Intestinal parasites are the most common infections in developing countries. Prevalence and impacts of these parasites are high in pregnant women. The aims of this study were to determine prevalence of helmint...

    Authors: Berhanu Elfu Feleke and Tadesse Hailu Jember

    Citation: BMC Infectious Diseases 2018 18:373

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  14. Content type: Case report

    Primary amoebic meningoencephalitis (PAM), caused by Naegleria fowleri, is a rare protozoan infectious disease in China. A fatality rate of over 95% had been reported due to extremely rapid disease progression in...

    Authors: Qiang Wang, Jianming Li, Jingkai Ji, Liuqing Yang, Li Chen, Rongrong Zhou, Yang Yang, Haixia Zheng, Jing Yuan, Liqiang Li, Yuhai Bi, George F. Gao, Jinmin Ma and Yingxia Liu

    Citation: BMC Infectious Diseases 2018 18:349

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  15. Content type: Research article

    Cystic echinococcosis (CE) is a well-known neglected parasitic disease. However, evidence supporting the four current treatment modalities is inadequate, and treatment options remain controversial. The aim of ...

    Authors: Virginia Velasco-Tirado, Montserrat Alonso-Sardón, Amparo Lopez-Bernus, Ángela Romero-Alegría, Francisco Javier Burguillo, Antonio Muro, Adela Carpio-Pérez, Juan Luis Muñoz Bellido, Javier Pardo-Lledias, Miguel Cordero and Moncef Belhassen-García

    Citation: BMC Infectious Diseases 2018 18:306

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  16. Content type: Research article

    Toxoplasma gondii is a protozoan parasite with worldwide distribution, infecting a broad-range of humans and warm-blooded animals. In the current study, role of this parasite on secondary sex ratio and risk of mi...

    Authors: Saeedeh Shojaee, Aref Teimouri, Hossein Keshavarz, Sanaz Jafarpour Azami and Sahar Nouri

    Citation: BMC Infectious Diseases 2018 18:307

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  17. Content type: Research article

    Schistosomiasis, a neglected tropical disease caused by parasites that infest open water sources such as rivers and dams may increase susceptibility to HIV. Mass-treatment with praziquantel tablets, recommende...

    Authors: Andrea Lothe, Nqobile Zulu, Arne Olav Øyhus, Eyrun Floerecke Kjetland and Myra Taylor

    Citation: BMC Infectious Diseases 2018 18:239

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  18. Content type: Research article

    Chagas disease (CD) is a systemic parasitic infection caused by the protozoan Trypanosoma cruzi, whose chronic phase may lead to cardiac and intestinal disorders. Endemic in Latin America where it is transmitted ...

    Authors: Stefania Pane, Maria Letizia Giancola, Pierluca Piselli, Angela Corpolongo, Ernestina Repetto, Rita Bellagamba, Claudia Cimaglia, Stefania Carrara, Piero Ghirga, Alessandra Oliva, Nazario Bevilacqua, Ahmad Al Rousan, Carla Nisii, Giuseppe Ippolito and Emanuele Nicastri

    Citation: BMC Infectious Diseases 2018 18:212

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  19. Content type: Research article

    The front line molecules from filarial worms and other nematodes or helminthes are their Excretory-Secretory (ES) products. Their interaction with the host cells, proteins and immune system accounts for the sk...

    Authors: Djafsia Boursou, Dieudonné Ndjonka, Albert Eisenbarth, Kingsley Manchang, Archille Paguem, Nancy Ngwafu Ngwasiri, Jacqueline Dikti Vildina, Babette Abanda, Ralf Krumkamp, Silke van Hoorn, Alfons Renz, Mbunkah Daniel Achukwi, Eva Liebau and Norbert W. Brattig

    Citation: BMC Infectious Diseases 2018 18:200

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  20. Content type: Case report

    Thailand is a major destination for German travellers with more than 760,000 arrivals in 2015. At the same time, malaria is a concern in travel recommendations with regard to this destination. The World Malari...

    Authors: Guenter Froeschl, Marcus Beissner, Kristina Huber, Gisela Bretzel, Michael Hoelscher and Camilla Rothe

    Citation: BMC Infectious Diseases 2018 18:148

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  21. Content type: Case report

    In immunocompetent patients, acute toxoplasmosis is usually asymptomatic. We identified M1 macrophages in a case of symptomatic acute Toxoplasma gondii infection that resolved without treatment. M1 macrophages ha...

    Authors: Graziano De Luca, Chiara Di Lisio, Giuseppe Lattanzio, Tommaso D’Antuono, Marcella Liberatore and Francesca Bianca Aiello

    Citation: BMC Infectious Diseases 2018 18:139

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  22. Content type: Research article

    Glucose-6-phosphate dehydrogenase (G6PD; EC 1.1.1.49) deficiency is one of the most common X-linked recessive hereditary disorders in the world. Primaquine (PQ) has been used for radical cure of P. vivax to preve...

    Authors: Jinyoung Lee, Tae Im Kim, Jung-Mi Kang, Hojong Jun, Hương Giang Lê, Thị Lam Thái, Woon-Mok Sohn, Moe Kyaw Myint, Khin Lin, Tong-Soo Kim and Byoung-Kuk Na

    Citation: BMC Infectious Diseases 2018 18:131

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  23. Content type: Research article

    The zoonotic parasite Taenia solium is endemic in Angónia district, Tete province, Mozambique, though the burden of the disease complex is unknown.

    Authors: Chiara Trevisan, Brecht Devleesschauwer, Nicolas Praet, Alberto Pondja, Yunus Amade Assane, Pierre Dorny, Stig Milan Thamsborg, Pascal Magnussen and Maria Vang Johansen

    Citation: BMC Infectious Diseases 2018 18:127

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  24. Content type: Research article

    China has initiated the National Malaria Elimination Action Plan, which aims to eliminate malaria by 2020. However, the transmission of malaria occurs sporadically or in distinct foci, which greatly hampers pr...

    Authors: Jun Feng, Hong Tu, Li Zhang, Shaosen Zhang, Shan Jiang, Zhigui Xia and Shuisen Zhou

    Citation: BMC Infectious Diseases 2018 18:115

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  25. Content type: Research article

    Leishmaniasis, a vector borne tropical/subtropical disease caused by the protozoan Leishmania is transmitted to humans by sandfly vectors Phlebotomus and Lutzomyia. The principal form found in Sri Lanka is cutane...

    Authors: Devika Iddawela, Sanura Malinda Pallegoda Vithana, Dhilma Atapattu and Lanka Wijekoon

    Citation: BMC Infectious Diseases 2018 18:108

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  26. Content type: Case report

    Accurate and early diagnosis of neurocysticercosis (NCC) remains a challenge due to the heterogeneity of its clinical, immunological and imaging characteristics. The presence of cysticercus DNA in cerebrospina...

    Authors: Ping Liu, Xing Weng, Jiajia Zhou, Xiaolin Xu, Fangping He, Yue Du, Honglong Wu, Yanping Gong and Guoping Peng

    Citation: BMC Infectious Diseases 2018 18:113

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  27. Content type: Research article

    Schistosomiasis remains a global health problem with an estimated 250 million people in 78 countries infected, of whom 85% live in Sub-Saharan Africa. Preventive chemotherapy remains the key public health stra...

    Authors: Hlengiwe Sacolo, Moses Chimbari and Chester Kalinda

    Citation: BMC Infectious Diseases 2018 18:46

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  28. Content type: Research article

    Malaria is a major cause of morbidity and mortality. Treatment of malaria in a timely manner could avert deaths. Treatment ultimately relies on the rapid and accurate diagnosis. Fluorescence in situ hybridizat...

    Authors: Regina Kandie, Rachel Ochola and Kariuki Njaanake

    Citation: BMC Infectious Diseases 2018 18:22

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  29. Content type: Case report

    Hydatid disease is a worldwide zoonosis produced by the larval stage of cestodes of the Echinococcus genus. Hydatid disease primarily involves the liver and lungs. The brain is involved in less than 2% of cases. ...

    Authors: Shu Chen, Ning Li, Feifei Yang, Jiqin Wu, Yuekai Hu, Shenglei Yu, Qi Chen, Xuan Wang, Xinyu Wang, Yuanyuan Liu and Jianming Zheng

    Citation: BMC Infectious Diseases 2018 18:12

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  30. Content type: Research article

    The inefficiency of the current tachyzoite antigen-based serological assays for the serodiagnosis of Toxoplasma gondii infection mandates the need for acquirement of reliable and standard diagnostic reagents. Rec...

    Authors: Khalid Hajissa, Robaiza Zakaria, Rapeah Suppian and Zeehaida Mohamed

    Citation: BMC Infectious Diseases 2017 17:807

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  31. Content type: Research article

    Severe malaria is a medical emergency associated with high mortality. Adequate treatment requires initial parenteral therapy for fast parasite clearance followed by longer acting oral antimalarial drugs for cu...

    Authors: Pauline Byakika-Kibwika, Jane Achan, Mohammed Lamorde, Carine Karera-Gonahasa, Agnes N. Kiragga, Harriet Mayanja-Kizza, Noah Kiwanuka, Sam Nsobya, Ambrose O. Talisuna and Concepta Merry

    Citation: BMC Infectious Diseases 2017 17:794

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  32. Content type: Research article

    Leishmania donovani is the etiological agent of visceral leishmaniasis (VL) in the Indian subcontinent. However, it is also known to cause cutaneous leishmaniasis (CL) in Sri Lanka. Sr...

    Authors: Udeshika Lakmini Kariyawasam, Angamuthu Selvapandiyan, Keshav Rai, Tasaduq Hussain Wani, Kavita Ahuja, Mizra Adil Beg, Hasitha Upendra Premathilake, Narayan Raj Bhattarai, Yamuna Deepani Siriwardena, Daibin Zhong, Guofa Zhou, Suman Rijal, Hira Nakhasi and Nadira D. Karunaweera

    Citation: BMC Infectious Diseases 2017 17:791

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  33. Content type: Case report

    Alice in Wonderland” syndrome (AIWS) is a rare neurological abnormality characterized by distortions of visual perceptions, body schema and experience of time. AIWS has been reported ...

    Authors: Benjamin Momo Kadia, Cyril Jabea Ekabe and Ettamba Agborndip

    Citation: BMC Infectious Diseases 2017 17:789

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  34. Content type: Research article

    Artemisinin-based combination therapies (ACTs) have remained efficacious treatments of acute falciparum malaria in many endemic areas but there is little evaluation of factors contributing to the anaemia of ac...

    Authors: Akintunde Sowunmi, Bayo Fatunmbi, Kazeem Akano, Olubunmi A. Wewe, Chimere Agomo, Finomo Finomo, Joy Ebenebe, Nma Jiya, Jose Ambe, Robinson Wammanda, Godwin Ntadom, Olugbenga Mokuolu, George Emechebe, Nnenna Ezeigwe, Adejumoke I. Ayede, Elsie O. Adewoye…

    Citation: BMC Infectious Diseases 2017 17:781

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  35. Content type: Research article

    Recurrence rates of Plasmodium vivax infections differ across various geographic regions. Interestingly, South-East Asia and the Asia-Pacific region are documented to exhibit the most frequent recurrence incidenc...

    Authors: Norliza Mat Ariffin, Farida Islahudin, Endang Kumolosasi and Mohd Makmor-Bakry

    Citation: BMC Infectious Diseases 2017 17:759

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  36. Content type: Research article

    Previous studies showed that a naturally attenuated strain from Trypanosoma cruzi triggers an immune response mainly related to a Th2-type profile. Albeit this, a strong protection against virulent challenge was ...

    Authors: Cecilia Pérez Brandán, Andrea C. Mesías, Cecilia Parodi, Rubén O. Cimino, Carolina Pérez Brandán, Patricio Diosque and Miguel Ángel Basombrío

    Citation: BMC Infectious Diseases 2017 17:732

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  37. Content type: Research article

    Use of bednets reduces malaria morbidity and mortality. In Kilifi, Kenya, there was a mass distribution of free nets to children < 5 years in 2006. In 2009, a new policy was implemented to offer bednets to pre...

    Authors: Alice Kamau, Victoria Nyaga, Evasius Bauni, Benjamin Tsofa, Abdisalan M. Noor, Philip Bejon, J. Anthony G. Scott and Laura L. Hammitt

    Citation: BMC Infectious Diseases 2017 17:720

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  38. Content type: Case report

    Tapeworms of the genus Spirometra include species whose larval stages can infect humans, causing a disease called sparganosis. Cases of human infection with adult worms are very rare and have been reported in Kor...

    Authors: Anh Tran Le, Le-Quyen Thi Do, Huong-Binh Thi Nguyen, Hong-Ngoc Thi Nguyen and Anh Ngoc Do

    Citation: BMC Infectious Diseases 2017 17:669

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  39. Content type: Research article

    The objectives of this study were to determine the proportion of malaria, bacteraemia, scrub typhus, leptospirosis, chikungunya and dengue among hospitalized patients with acute undifferentiated fever in India...

    Authors: Kristine Mørch, Anand Manoharan, Sara Chandy, Novin Chacko, Gerardo Alvarez-Uria, Suvarna Patil, Anil Henry, Joel Nesaraj, Cijoy Kuriakose, Ashita Singh, Siby Kurian, Christel Gill Haanshuus, Nina Langeland, Bjørn Blomberg, George Vasanthan Antony and Dilip Mathai

    Citation: BMC Infectious Diseases 2017 17:665

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  40. Content type: Research article

    The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) focus is on randomized trials of different approaches to mass drug administration (MDA) in endemic countries in Africa. Because th...

    Authors: Ye Shen, Charles H. King, Sue Binder, Feng Zhang, Christopher C. Whalen, W. Evan Secor, Susan P. Montgomery, Pauline N. M. Mwinzi, Annette Olsen, Pascal Magnussen, Safari Kinung’hi, Anna E. Phillips, Rassul Nalá, Josefo Ferro, H. Osvaldo Aurelio, Fiona Fleming…

    Citation: BMC Infectious Diseases 2017 17:652

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  41. Content type: Study protocol

    Due to outdoor and residual transmission and insecticide resistance, long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) will be insufficient as stand-alone malaria vector control interve...

    Authors: Robert S. McCann, Henk van den Berg, Peter J. Diggle, Michèle van Vugt, Dianne J. Terlouw, Kamija S. Phiri, Aurelio Di Pasquale, Nicolas Maire, Steven Gowelo, Monicah M. Mburu, Alinune N. Kabaghe, Themba Mzilahowa, Michael G. Chipeta and Willem Takken

    Citation: BMC Infectious Diseases 2017 17:639

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  42. Content type: Research article

    Radiotherapy may represent an alternative treatment modality for cystic echinococcosis (CE), but there is no adequate evidence for it up to now. In this study, we aim to investigate the parasiticidal effects o...

    Authors: Rui Mao, Ge Wu, Hui Wang, Pengfei Lu, Jun Li, Haitao Li, Aimudula Ainiwaer, Yiwei Bai, Mingyang Shu, Yongxing Bao and Wenbao Zhang

    Citation: BMC Infectious Diseases 2017 17:636

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  43. Content type: Research article

    Local understandings of malaria and use of preventive measures-are critical factors in sustained control of malaria. This study assessed caretakers’ knowledge on malaria, use of Long Lasting Insecticide Treate...

    Authors: Zewdie Birhanu, Yemane Ye-ebiyo Yihdego and Delenasaw Yewhalaw

    Citation: BMC Infectious Diseases 2017 17:629

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  44. Content type: Research article

    Human strongyloidiasis is a chronic and persistent gastrointestinal disease caused by infection with soil-transmitted helminths of the genus Strongyloides. The aim of this research was to obtain diagnostic preval...

    Authors: Thidarat K. Prasongdee, Pokkamol Laoraksawong, Wanida Kanarkard, Ratthaphol Kraiklang, Kraisit Sathapornworachai, Sureeporn Naonongwai, Porntip Laummaunwai, Oranuch Sanpool, Pewpan M. Intapan and Wanchai Maleewong

    Citation: BMC Infectious Diseases 2017 17:627

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  45. Content type: Research article

    A simple and accurate molecular diagnostic method for malaria is urgently needed due to the limitations of conventional microscopic examination. In this study, we demonstrate a new diagnostic procedure for hum...

    Authors: Kazuo Imai, Norihito Tarumoto, Kazuhisa Misawa, Lucky Ronald Runtuwene, Jun Sakai, Kyoko Hayashida, Yuki Eshita, Ryuichiro Maeda, Josef Tuda, Takashi Murakami, Shigefumi Maesaki, Yutaka Suzuki, Junya Yamagishi and Takuya Maeda

    Citation: BMC Infectious Diseases 2017 17:621

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  46. Content type: Research article

    The PfEMP1 family of Plasmodium falciparum antigens play a key role in pathogenesis of severe malaria through their insertion into the surface of parasite infected erythrocytes, and adhesion to host cells. Previo...

    Authors: Abdirahman I. Abdi, Susanne H. Hodgson, Michelle K. Muthui, Cheryl A. Kivisi, Gathoni Kamuyu, Domtila Kimani, Stephen L. Hoffman, Elizabeth Juma, Bernhards Ogutu, Simon J. Draper, Faith Osier, Philip Bejon, Kevin Marsh and Peter C. Bull

    Citation: BMC Infectious Diseases 2017 17:585

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  47. Content type: Research article

    Parenteral artesunate is the treatment of choice for severe malaria. Recently, haemolytic anaemia occurring 1 to 3 weeks after artesunate treatment of falciparum malaria has been reported in returning travellers ...

    Authors: C. Fanello, M. Onyamboko, S. J. Lee, C. Woodrow, S. Setaphan, K. Chotivanich, P. Buffet, S. Jauréguiberry, K. Rockett, K. Stepniewska, N. P. J. Day, N. J. White and A. M. Dondorp

    Citation: BMC Infectious Diseases 2017 17:575

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  48. Content type: Research article

    Sickle Cell Trait (SCT) has been shown to be protective against malaria. A growing literature suggests that malaria exposure can reduce educational attainment. This study assessed the relationship and interact...

    Authors: Kevin Croke, Deus S. Ishengoma, Filbert Francis, Julie Makani, Mathias L. Kamugisha, John Lusingu, Martha Lemnge, Horacio Larreguy, Günther Fink and Bruno P. Mmbando

    Citation: BMC Infectious Diseases 2017 17:568

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  49. Content type: Research article

    Skin ulcers in American cutaneous leishmaniasis (ACL) may heal spontaneously after months/years. However, few cases may present quick heal even during diagnosis procedure (early spontaneous healing- ESH). The ...

    Authors: Carla Oliveira-Ribeiro, Maria Inês Fernandes Pimentel, Raquel de Vasconcellos Carvalhaes Oliveira, Aline Fagundes, Maria de Fatima Madeira, Cintia Xavier Mello, Eliame Mouta-Confort, Claudia Maria Valete-Rosalino, Erica de Camargo Ferreira Vasconcellos, Marcelo Rosandiski Lyra, Leonardo Pereira Quintella, Liliane de Fatima Antonio, Armando Schubach and Fatima Conceição-Silva

    Citation: BMC Infectious Diseases 2017 17:559

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  50. Content type: Research article

    Henan Province has been in the malaria elimination stage, with all reports of the disease being imported since 2012 and over 90% coming from Africa. Surveillance and population studies are essential for the ea...

    Authors: Chengyun Yang, Hongwei Zhang, Ruimin Zhou, Dan Qian, Ying Liu, Yuling Zhao, Suhua Li and Bianli Xu

    Citation: BMC Infectious Diseases 2017 17:560

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