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BMC Infectious Diseases

HIV and co-infections

Section edited by Carlo Torti and Andrea De Luca

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of HIV and HIV-associated infections in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section also aims to publish studies on the adverse events of HAART and non HIV-related comorbidities in the HAART era.

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  1. Content type: Research article

    Switch strategies based on rilpivirine/tenofovir/emtricitabine or on an integrase inhibitor (InSTI) plus tenofovir/emtricitabine have never been compared in randomized clinical trials. The main aim of the stud...

    Authors: Nicola Gianotti, Andrea Poli, Silvia Nozza, Laura Galli, Nadia Galizzi, Marco Ripa, Marco Merli, Alessia Carbone, Vincenzo Spagnuolo, Adriano Lazzarin and Antonella Castagna

    Citation: BMC Infectious Diseases 2017 17:723

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  2. Content type: Research article

    There is ongoing controversy regarding abacavir use in the treatment of HIV infection and the risk of subsequent development of cardiovascular disease. It is unclear how the risk varies as exposure accumulates.

    Authors: Kunchok Dorjee, Sanjiv M. Baxi, Arthur L. Reingold and Alan Hubbard

    Citation: BMC Infectious Diseases 2017 17:708

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  3. Content type: Research article

    Early HIV diagnosis and initiation onto antiretroviral therapy may prevent ongoing spread of HIV. Risk Tracing Snowball Approach (RTSA) has been shown to be effective in detecting new HIV cases in other settin...

    Authors: Srean Chhim, John Macom, Chettana Pav, Nirada Nim, Phearun Yun, Sopheap Seng, Kolab Chhim, Sovannary Tuot and Siyan Yi

    Citation: BMC Infectious Diseases 2017 17:689

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  4. Content type: Research article

    Enterocytozoon bieneusi has been increasingly reported to infect humans and various mammals. Microsporidia cause diarrhea in HIV-infected patients worldwide. PCR amplification and sequ...

    Authors: Hua Liu, Zhihua Jiang, Zhongying Yuan, Jianhai Yin, Zunfu Wang, Bingxue Yu, Dongsheng Zhou, Yujuan Shen and Jianping Cao

    Citation: BMC Infectious Diseases 2017 17:684

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  5. Content type: Research article

    Despite young people being a key population for HIV prevention, the HIV epidemic amongst young Brazilians is perceived to be growing. We therefore reviewed all published literature on HIV prevalence and risk f...

    Authors: Igor Pedrosa Saffier, Hélia Kawa and Guy Harling

    Citation: BMC Infectious Diseases 2017 17:675

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  6. Content type: Research article

    There is limited information on patterns of treatment change among new initiators of highly active antiretroviral therapy (HAART) in the regions most affected by HIV/AIDS. This makes it difficult to identify t...

    Authors: Daniel N. A. Ankrah, Margaret Lartey, Aukje K. Mantel-Teeuwisse and Hubert G. M. Leufkens

    Citation: BMC Infectious Diseases 2017 17:664

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  7. Content type: Research article

    Dolutegravir (DTG) plus darunavir/ritonavir (DRV/r) is a simple combination of drugs that has the best genetic barrier to HIV-1 resistance and may be fit for salvage therapy.

    Authors: Amedeo F. Capetti, Maria Vittoria Cossu, Giancarlo Orofino, Gaetana Sterrantino, Giovanni Cenderello, Giuseppe V. De Socio, Anna Maria Cattelan, Alessandro Soria, Stefano Rusconi, Niccolò Riccardi, Gian Maria Baldin, Fosca P. Niero, Giorgio Barbarini and Giuliano Rizzardini

    Citation: BMC Infectious Diseases 2017 17:658

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  8. Content type: Research article

    Accurately identifying individuals who are on antiretroviral therapy (ART) is important to determine ART coverage and proportion on ART who are virally suppressed. ART is also included in recent infection test...

    Authors: Helena Huerga, Fisseha Shiferie, Eduard Grebe, Ruggero Giuliani, Jihane Ben Farhat, Gilles Van-Cutsem and Karen Cohen

    Citation: BMC Infectious Diseases 2017 17:653

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  9. Content type: Case report

    Hemophagocytic lymphohistiocytosis (HLH) is an uncommon systemic inflammatory condition that can result from infections, autoimmune diseases and malignancies. It is a rarely reported life threatening complicat...

    Authors: Farheen Manji, Evan Wilson, Etienne Mahe, John Gill and John Conly

    Citation: BMC Infectious Diseases 2017 17:633

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  10. Content type: Research article

    Dolutegravir (DTG) is metabolized mainly by uridine diphosphate (UDP)-glucuronosyltransferase 1A1 (UGT1A1), and partly by cytochrome P450 3A (CYP3A). Therefore, we focused on UGT1A1 gene polymorphisms (*6 and *28...

    Authors: Hiroki Yagura, Dai Watanabe, Hiroyuki Kushida, Kosuke Tomishima, Hiroaki Togami, Atsushi Hirano, Masaaki Takahashi, Kazuyuki Hirota, Motoko Ikuma, Daisuke Kasai, Yasuharu Nishida, Munehiro Yoshino, Kunio Yamazaki, Tomoko Uehira and Takuma Shirasaka

    Citation: BMC Infectious Diseases 2017 17:622

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  11. Content type: Research article

    The clinical care of people living with HIV changed fundamentally as a result of the development of effective antiretroviral therapy (ART). HIV infection is now a long-term treatable condition. We report a nat...

    Authors: A. Molloy, H. Curtis, F. Burns and A. Freedman

    Citation: BMC Infectious Diseases 2017 17:619

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  12. Content type: Study protocol

    With potent antiretroviral drugs, HIV infection is becoming a chronic disease. Emergence of comorbidities, particularly cardiovascular disease (CVD) has become a leading concern for patients living with the in...

    Authors: Madeleine Durand, Carl Chartrand-Lefebvre, Jean-Guy Baril, Sylvie Trottier, Benoit Trottier, Marianne Harris, Sharon Walmsley, Brian Conway, Alexander Wong, Jean-Pierre Routy, Colin Kovacs, Paul A. MacPherson, Kenneth Marc Monteith, Samer Mansour, George Thanassoulis, Michal Abrahamowicz…

    Citation: BMC Infectious Diseases 2017 17:611

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  13. Content type: Research article

    Little is known regarding the restoration of the specific immune response after combined antiretroviral therapy (cART) and anti-tuberculosis (TB) therapy introduction among TB-HIV patients. In this study, we e...

    Authors: Tatiana Pereira da Silva, Carmem Beatriz Wagner Giacoia-Gripp, Carolina A. Schmaltz, Flavia Marinho Sant’Anna, Maria Helena Saad, Juliana Arruda de Matos, Julio Castro Alves de Lima e Silva, Valeria Cavalcanti Rolla and Mariza Gonçalves Morgado

    Citation: BMC Infectious Diseases 2017 17:606

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  14. Content type: Research article

    We describe the accumulation of HIV-1 drug resistance and its effect on the activity of next-line components in patients with virological failure (HIV-1 RNA >1000 copies/mL) after 1 year (t1) of first-line ant...

    Authors: Andrea De Luca, Zita Jorge Sidumo, Giacomo Zanelli, Noorjehan Abdul Magid, Richard Luhanga, Davide Brambilla, Giuseppe Liotta, Sandro Mancinelli, Maria Cristina Marazzi, Leonardo Palombi and Susanna Ceffa

    Citation: BMC Infectious Diseases 2017 17:605

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  15. Content type: Review

    Current antiretroviral therapy (ART) used to treat human immunodeficiency virus (HIV) patients is life-long because it only suppresses de novo infections. Recent efforts to eliminate HIV have tested the abilit...

    Authors: Kristian Thorlund, Marc S. Horwitz, Brian T. Fife, Richard Lester and D. William Cameron

    Citation: BMC Infectious Diseases 2017 17:595

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  16. Content type: Research article

    Switch from first to second-line ART is recommended by WHO for patients with virologic failure. Delays in switching may contribute to accumulated drug resistance, advanced immunosuppression, increased morbidit...

    Authors: Victor Ssempijja, Gertrude Nakigozi, Larry Chang, Ron Gray, Maria Wawer, Anthony Ndyanabo, Jingo Kasule, David Serwadda, Barbara Castelnuovo, Anja van’t Hoog and Steven James Reynolds

    Citation: BMC Infectious Diseases 2017 17:582

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  17. Content type: Research article

    Persistent residual viremia (RV) and low grade inflammation and immune activation have been associated with non-AIDS defining events. The impact of persistent RV and HIV-DNA load on immune activation/inflammat...

    Authors: Francesca Falasca, Daniele Di Carlo, Corrado De Vito, Isabella Bon, Gabriella d’Ettorre, Alessandra Fantauzzi, Ivano Mezzaroma, Caterina Fimiani, Maria Carla Re, Vincenzo Vullo, Guido Antonelli and Ombretta Turriziani

    Citation: BMC Infectious Diseases 2017 17:581

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  18. Content type: Review

    Aim of this review is to focus the attention on people living with HIV infection at risk of developing a cardiovascular event. What is or what would be the most suitable antiretroviral therapy? Which statin or...

    Authors: Paolo Maggi, Antonio Di Biagio, Stefano Rusconi, Stefania Cicalini, Maurizio D’Abbraccio, Gabriella d’Ettorre, Canio Martinelli, Giuseppe Nunnari, Laura Sighinolfi, Vincenzo Spagnuolo and Nicola Squillace

    Citation: BMC Infectious Diseases 2017 17:551

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  19. Content type: Research article

    UNAIDS calls for fewer than 500,000 new HIV infections/year by 2020, with treatment-as-prevention being a key part of their strategy for achieving the target. A better understanding of the contribution to tran...

    Authors: Nicky McCreesh, Ioannis Andrianakis, Rebecca N. Nsubuga, Mark Strong, Ian Vernon, Trevelyan J. McKinley, Jeremy E. Oakley, Michael Goldstein, Richard Hayes and Richard G. White

    Citation: BMC Infectious Diseases 2017 17:557

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