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HIV and co-infections

Section edited by Carlo Torti and Andrea De Luca

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of HIV and HIV-associated infections in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section also aims to publish studies on the adverse events of HAART and non HIV-related comorbidities in the HAART era.

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  1. Content type: Research article

    Natural killer (NK) cells play cytotoxic roles by targeting tumor cells or virus infected cells, they also play regulatory roles by secreting cytokines and chemokines. Transforming growth factor (TGF)-β and in...

    Authors: Yongjun Jiang, Mei Yang, Xiaojuan Sun, Xi Chen, Meichen Ma, Xiaowan Yin, Shi Qian, Zining Zhang, Yajing Fu, Jing Liu, Xiaoxu Han, Junjie Xu and Hong Shang

    Citation: BMC Infectious Diseases 2018 18:80

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  2. Content type: Study protocol

    The World Health Organization (WHO) recommends viral load (VL) measurement as the preferred monitoring strategy for HIV-infected individuals on antiretroviral therapy (ART) in resource-limited settings. The ne...

    Authors: Alain Amstutz, Bienvenu Lengo Nsakala, Fiona Vanobberghen, Josephine Muhairwe, Tracy Renée Glass, Beatrice Achieng, Mamorena Sepeka, Katleho Tlali, Lebohang Sao, Kyaw Thin, Thomas Klimkait, Manuel Battegay and Niklaus Daniel Labhardt

    Citation: BMC Infectious Diseases 2018 18:76

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  3. Content type: Research article

    Previous studies have shown that the increased coverage of antiretroviral therapy (ART) could reduce the community viral load (CVL) and reduce the occurrence of new HIV infections. However, the impact on the r...

    Authors: Lin He, Jiezhe Yang, Qiaoqin Ma, Jiafeng Zhang, Yun Xu, Yan Xia, Wanjun Chen, Hui Wang, Jinlei Zheng, Jun Jiang, Yan Luo, Ke Xu, Xingliang Zhang, Shichang Xia and Xiaohong Pan

    Citation: BMC Infectious Diseases 2018 18:62

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  4. Content type: Research article

    Early presentation for HIV care is vital as an initial tread in the UNAIDS 90–90–90 targets. However, late presentation for HIV care (LP) challenges achieving the targets. This study assessed the prevalence, t...

    Authors: Hailay Abrha Gesesew, Paul Ward, Kifle Woldemichael and Lillian Mwanri

    Citation: BMC Infectious Diseases 2018 18:59

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  5. Content type: Research article

    With over 1 million HIV-related deaths annually, quality end-of-life care remains a priority. Given strong public preference for home death, place of death is an important consideration for quality care. This ...

    Authors: Richard Harding, Stefano Marchetti, Bregje D. Onwuteaka-Philipsen, Donna M. Wilson, Miguel Ruiz-Ramos, Maria Cardenas-Turanzas, YongJoo Rhee, Lucas Morin, Katherine Hunt, Joan Teno, Cecilia Hakanson, Dirk Houttekier, Luc Deliens and Joachim Cohen

    Citation: BMC Infectious Diseases 2018 18:55

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  6. Content type: Case report

    The majority of people living with HIV require antiretroviral therapy (ART) for controlling viral replication, however there are rare HIV controllers who spontaneously and durably control HIV in the absence of...

    Authors: Yumna Moosa, Ramla F. Tanko, Veron Ramsuran, Ravesh Singh, Mashudu Madzivhandila, Nonhlanhla Yende-Zuma, Melissa-Rose Abrahams, Philippe Selhorst, Kamini Gounder, Penny L. Moore, Carolyn Williamson, Salim S. Abdool Karim, Nigel J. Garrett and Wendy A. Burgers

    Citation: BMC Infectious Diseases 2018 18:54

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  7. Content type: Research article

    Anemia is common among people living with HIV infection and is frequently associated with poor quality of life and poor prognosis. It has been well described in antiretroviral naïve individuals and those on no...

    Authors: McNeil Ngongondo, Nora E. Rosenberg, Christopher C. Stanley, Robertino Lim, Dennis Ongubo, Richard Broadhurst, Colin Speight, Robert Flick, Petros Tembo and Mina C. Hosseinpour

    Citation: BMC Infectious Diseases 2018 18:39

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  8. Content type: Research article

    Combined antiretroviral therapy (cART) in HIV-infected patients has been associated with lipodystrophy, metabolic abnormalities, and an increased risk of cardiovascular disease. Ultrasound measures of carotid ...

    Authors: Maria Teresa Beires, André Silva-Pinto, Ana Cristina Santos, António José Madureira, Jorge Pereira, Davide Carvalho, António Sarmento and Paula Freitas

    Citation: BMC Infectious Diseases 2018 18:32

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  9. Content type: Research article

    A new model of care is required to meet the changing needs of people living with HIV (PLWH), particularly in low and middle-income countries, where prevalence is highest. We evaluated a palliative care interve...

    Authors: Keira Lowther, Richard Harding, Victoria Simms, Aabid Ahmed, Zipporah Ali, Nancy Gikaara, Lorraine Sherr, Hellen Kariuki, Irene J. Higginson and Lucy Ellen Selman

    Citation: BMC Infectious Diseases 2018 18:27

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  10. Content type: Research article

    Metabolic and cardiovascular diseases (CVD) represent a major problem in HIV infection. The aim of this study was to evaluate the relationship of HIV infection and antiretroviral therapy (ART) with circulating...

    Authors: Mario Luca Morieri, Viola Guardigni, Juana Maria Sanz, Edoardo Dalla Nora, Cecilia Soavi, Giovanni Zuliani, Laura Sighinolfi and Angelina Passaro

    Citation: BMC Infectious Diseases 2018 18:10

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  11. Content type: Case report

    Individuals lacking immune recovery during suppressive cART will still represent a clinical issue in the years to come, given the high proportion of HIV-infected subjects introducing therapy late in the course...

    Authors: Camilla Tincati, Esther Merlini, Antonella d’Arminio Monforte and Giulia Marchetti

    Citation: BMC Infectious Diseases 2018 18:8

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  12. Content type: Research article

    Newly diagnosed HIV-positive men who have sex with men (MSM) are an important subgroup in HIV intervention. How newly diagnosed HIV-positive MSM look at HIV/AIDS is consequential and is potentially associated ...

    Authors: Xiaobing Wu, Joseph T. F. Lau, Winnie W. S. Mak, Jing Gu, Phoenix K. H. Mo and Xiaodong Wang

    Citation: BMC Infectious Diseases 2018 18:2

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  13. Content type: Research article

    The HIV-1 DNA reservoir is an important marker that reflects viro-immunological status and can be affected by multiple viral or cellular factors. Determining the potential factors associated with the size of t...

    Authors: Yongsong Yue, Nidan Wang, Yang Han, Ting Zhu, Jing Xie, Zhifeng Qiu, Xiaojing Song, Yanling Li, Jean-Pierre Routy, Jianhua Wang and Taisheng Li

    Citation: BMC Infectious Diseases 2017 17:771

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  14. Content type: Research article

    The outbreak of the Ebola virus disease (EVD) in 2014 led to massive dropouts in HIV care in Guinea. Meanwhile, Médecins Sans Frontières (MSF) was implementing a six-monthly appointment spacing approach adapte...

    Authors: Cavin Epie Bekolo, Abdourahimi Diallo, Mit Philips, Joseph-Desire Yuma, Letizia Di Stefano, Stéphanie Drèze, Jerome Mouton, Youssouf Koita and Ousseni W. Tiomtore

    Citation: BMC Infectious Diseases 2017 17:766

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  15. Content type: Research article

    According to World Health Organization (WHO) guidelines, which have also been adopted by the National AIDS Control Organization (NACO), India, Efavirenz-based Anti-Retroviral Therapy (ART) is better in Human-I...

    Authors: Sanjeev Sinha, Kartik Gupta, Srikanth Tripathy, Sahajal Dhooria, Sanjay Ranjan and R. M. Pandey

    Citation: BMC Infectious Diseases 2017 17:761

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  16. Content type: Research article

    There is today no gold standard method to accurately define the time passed since infection at HIV diagnosis. Infection timing and incidence measurement is however essential to better monitor the dynamics of l...

    Authors: Chris Verhofstede, Katrien Fransen, Annelies Van Den Heuvel, Kristel Van Laethem, Jean Ruelle, Ellen Vancutsem, Karolien Stoffels, Sigi Van den Wijngaert, Marie-Luce Delforge, Dolores Vaira, Laura Hebberecht, Marlies Schauvliege, Virginie Mortier, Kenny Dauwe and Steven Callens

    Citation: BMC Infectious Diseases 2017 17:738

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  17. Content type: Research article

    Before Pre-Exposure Prophylaxis (PrEP) was officially recommended and made available, a few surveys among gay and bisexual men, and persons living with HIV/AIDS (PLWHA), identified an informal use of antiretro...

    Authors: Antonio Palummieri, Gabriella De Carli, Éric Rosenthal, Patrice Cacoub, Cristina Mussini and Vincenzo Puro

    Citation: BMC Infectious Diseases 2017 17:734

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  18. Content type: Research article

    Knowledge of HIV status can be important in reducing the risk of HIV exposure. In a European sample of men-who-have-sex-with-men (MSM), we aimed to identify factors associated with HIV serostatus disclosure to...

    Authors: Ulrich Marcus, Susanne Barbara Schink, Nigel Sherriff, Anna-Marie Jones, Lorenzo Gios, Cinta Folch, Torsten Berglund, Christiana Nöstlinger, Marta Niedźwiedzka-Stadnik, Sonia F. Dias, Ana F. Gama, Emilia Naseva, Ivailo Alexiev, Danica Staneková, Igor Toskin, Daniela Pitigoi…

    Citation: BMC Infectious Diseases 2017 17:730

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  19. Content type: Research article

    Switch strategies based on rilpivirine/tenofovir/emtricitabine or on an integrase inhibitor (InSTI) plus tenofovir/emtricitabine have never been compared in randomized clinical trials. The main aim of the stud...

    Authors: Nicola Gianotti, Andrea Poli, Silvia Nozza, Laura Galli, Nadia Galizzi, Marco Ripa, Marco Merli, Alessia Carbone, Vincenzo Spagnuolo, Adriano Lazzarin and Antonella Castagna

    Citation: BMC Infectious Diseases 2017 17:723

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  20. Content type: Research article

    There is ongoing controversy regarding abacavir use in the treatment of HIV infection and the risk of subsequent development of cardiovascular disease. It is unclear how the risk varies as exposure accumulates.

    Authors: Kunchok Dorjee, Sanjiv M. Baxi, Arthur L. Reingold and Alan Hubbard

    Citation: BMC Infectious Diseases 2017 17:708

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