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HIV and co-infections

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of HIV and HIV-associated infections in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section also aims to publish studies on the adverse events of HAART and non HIV-related comorbidities in the HAART era.

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  1. The leading causes of morbidity and mortality for people in high-income countries living with HIV are now non-AIDS malignancies, cardiovascular disease and other non-communicable diseases associated with agein...

    Authors: Sarity Dodson, Karen M. Klassen, Karalyn McDonald, Tanya Millard, Richard H. Osborne, Malcolm W. Battersby, Christopher K. Fairley, Julie A. Simpson, Paula Lorgelly, Andrew Tonkin, Janine Roney, Sean Slavin, Jasminka Sterjovski, Margot Brereton, Sharon R. Lewin, Levinia Crooks…

    Citation: BMC Infectious Diseases 2016 16:114

    Content type: Study protocol

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  2. Sentinel surveillance for HIV among women attending antenatal clinics using unlinked anonymous testing is a cornerstone of HIV surveillance in sub-Saharan Africa. Increased use of routine antenatal HIV testing...

    Authors: Martin Sirengo, George W. Rutherford, Boaz Otieno-Nyunya, Timothy A. Kellogg, Davies Kimanga, Nicholas Muraguri, Mamo Umuro, Joy Mirjahangir, Ellen Stein, Margaret Ndisha and Andrea A. Kim

    Citation: BMC Infectious Diseases 2016 16:113

    Content type: Research article

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  3. The range of combination antiretroviral therapy (cART) regimens available in many middle-income countries differs from those suggested in international HIV treatment guidelines. We compared first-line cART reg...

    Authors: Gordana Dragovic, Colette J. Smith, Djordje Jevtovic, Bozana Dimitrijevic, Jovana Kusic, Mike Youle and Margaret A. Johnson

    Citation: BMC Infectious Diseases 2016 16:106

    Content type: Research article

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  4. Musculoskeletal manifestations of the human immunodeficiency virus (HIV) have been described since the outset of the global HIV epidemic. Articular syndromes that have been described in association with HIV in...

    Authors: T. Adizie, R. J. Moots, B. Hodkinson, N. French and A. O. Adebajo

    Citation: BMC Infectious Diseases 2016 16:100

    Content type: Research article

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  5. Prevention of mother-to-child transmission of HIV (PMTCT) programs collect socio-demographic and HIV testing information similar to that collected by unlinked anonymous testing sero-surveillance (UAT) in anten...

    Authors: E. Gonese, A. Mushavi, M. Mungati, M. Mhangara, J. Dzangare, O. Mugurungi, J. Dee, P. H. Kilmarx, G. Shambira, M. T. Tshimanga and J. Hargrove

    Citation: BMC Infectious Diseases 2016 16:97

    Content type: Research article

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  6. Cancer is responsible for elevated HIV-related morbidity and mortality. Research on HIV-infected patients with concurrent cancer is rare in China. The purpose of our study was to investigate the prevalence and...

    Authors: Jun Yang, Shu Su, Hongxin Zhao, Dennis Wang, Jiali Wang, Fujie Zhang and Yan Zhao

    Citation: BMC Infectious Diseases 2016 16:82

    Content type: Research article

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  7. No Danish guidelines for screening of sexually transmitted infections (STIs) in women living with HIV (WLWH) exist, except for annual syphilis testing. Drug-drug interaction between hormonal contraceptives and...

    Authors: Kristina Thorsteinsson, Steen Ladelund, Merete Storgaard, Frederikke Falkencrone Rønsholt, Isik Somuncu Johansen, Gitte Pedersen, Lars Nørregård Nielsen, Jesper Bonde, Henrik Westh, Niels Obel, Terese L. Katzenstein and Anne-Mette Lebech

    Citation: BMC Infectious Diseases 2016 16:81

    Content type: Research article

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  8. The National Study of HIV in Pregnancy and Childhood (NSHPC) conducts comprehensive population-based surveillance of pregnancies in women with HIV infection in the United Kingdom/Ireland. Use of antepartum ant...

    Authors: Pat A. Tookey, Claire Thorne, Jean van Wyk and Michael Norton

    Citation: BMC Infectious Diseases 2016 16:65

    Content type: Research article

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  9. HIV-infected children in sub-Saharan Africa may be at a high risk of staying on a failing first-line regimen and developing drug-resistance HIV variants due to lack of routine viral load monitoring. We investi...

    Authors: Omobolawa Kukoyi, Lorna Renner, Jonathan Powell, Oliver Barry, Meghan Prin, Jonas Kusah, Xiangyu Cong and Elijah Paintsil

    Citation: BMC Infectious Diseases 2016 16:58

    Content type: Research article

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  10. Efavirenz, widely used as part of antiretroviral drug regimens in the treatment of paediatric human immunodeficiency virus infection, has central nervous system side effects. We describe four children presenti...

    Authors: Francoise Pinillos, Collet Dandara, Marelize Swart, Renate Strehlau, Louise Kuhn, Faeezah Patel, Ashraf Coovadia and Elaine Abrams

    Citation: BMC Infectious Diseases 2016 16:56

    Content type: Case report

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  11. Multicentric Castleman’s disease (MCD) is a pre-malignancy that presents with lymphadenopathy and features of systemic inflammation. Human immunodeficiency virus (HIV)-associated MCD is associated with human h...

    Authors: Stephanie Anderson, Sarah C. Sasson, Frederick J. Lee, Wendy Cooper, Stephen Larsen and Roger Garsia

    Citation: BMC Infectious Diseases 2016 16:53

    Content type: Case report

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  12. In 2010, to reduce late HIV diagnosis, the French national health agency endorsed non-targeted HIV screening in health care settings. Despite these recommendations, non-targeted screening has not been implemen...

    Authors: Judith Leblanc, Alexandra Rousseau, Gilles Hejblum, Isabelle Durand-Zaleski, Pierre de Truchis, France Lert, Dominique Costagliola, Tabassome Simon and Anne-Claude Crémieux

    Citation: BMC Infectious Diseases 2016 16:51

    Content type: Study protocol

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  13. In sub-Saharan Africa (SSA), antiretroviral therapy (ART) can prolong life for HIV-infected patients. However, patients initiating ART, especially in routine treatment programs, commonly dropout from care eith...

    Authors: Stephen B. Asiimwe, Michael Kanyesigye, Bosco Bwana, Samson Okello and Winnie Muyindike

    Citation: BMC Infectious Diseases 2016 16:43

    Content type: Research article

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  14. Artemether-lumefantrine is currently the most widely recommended treatment of uncomplicated malaria. Lopinavir–based antiretroviral therapy is the commonly recommended second-line HIV treatment. Artemether and...

    Authors: T. Kredo, K. Mauff, L. Workman, J. S. Van der Walt, L. Wiesner, P. J. Smith, G. Maartens, K. Cohen and K. I. Barnes

    Citation: BMC Infectious Diseases 2016 16:30

    Content type: Research article

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  15. Killer-cell Immunoglobulin-like Receptors(KIR) interact with Human Leukocyte Antigen(HLA) to modify natural killer- and T-cell function. KIR are implicated in HIV acquisition by small studies that have not bee...

    Authors: V. Naranbhai, D. de Assis Rosa, L. Werner, R. Moodley, H. Hong, A. Kharsany, K. Mlisana, S. Sibeko, N. Garrett, D. Chopera, W. H. Carr, Q. Abdool Karim, A. V. S. Hill, S. S. Abdool Karim, M. Altfeld, C. M. Gray…

    Citation: BMC Infectious Diseases 2016 16:27

    Content type: Research article

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  16. Provider-initiated HIV testing and counselling (PITC) is promoted as a means to increase HIV case finding. We assessed the effectiveness of PITC to increase HIV testing rate and HIV case finding among outpatie...

    Authors: Felix R. Kayigamba, Daniëla Van Santen, Mirjam I. Bakker, Judith Lammers, Veronicah Mugisha, Emmanuel Bagiruwigize, Ludwig De Naeyer, Anita Asiimwe and Maarten F. Schim Van Der Loeff

    Citation: BMC Infectious Diseases 2016 16:26

    Content type: Research article

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  17. Epstein Barr virus (EBV) and human papillomavirus (HPV) can co-exist in pharyngeal and cervical malignancies. However, the natural history and factors associated with persistent HPV infection among HIV-infecte...

    Authors: Sara Gianella, Christine C. Ginocchio, Eric S. Daar, Michael P. Dube and Sheldon R. Morris

    Citation: BMC Infectious Diseases 2016 16:24

    Content type: Research article

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  18. In Zimbabwe, sputum smear microscopy (SSM) is the routinely used TB diagnostic tool in hospitalised HIV-infected patients. However, SSM has poor sensitivity in HIV-infected patients. We compared performance of...

    Authors: Lynn Sodai Zijenah, Gerard Kadzirange, Tsitsi Bandason, Maria Mary Chipiti, Bevel Gwambiwa, Forget Makoga, Pauline Chungu, Philip Kaguru and Keertan Dheda

    Citation: BMC Infectious Diseases 2016 16:20

    Content type: Research article

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  19. Despite the progress in the Prevention of the Mother-to-Child Transmission of HIV (PMTCT), the paediatric HIV epidemic remains worrying in Cameroon. HIV prevalence rate for the population of pregnant women was...

    Authors: Hermine L. Nguena Nguefack, Henri Gwet, Sophie Desmonde, Odile Ouwe Missi Oukem-Boyer, Céline Nkenfou, Mathurin Téjiokem, Patrice Tchendjou, Irénée Domkam, Valériane Leroy and Ahmadou Alioum

    Citation: BMC Infectious Diseases 2016 16:11

    Content type: Research article

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  20. Early antiretroviral therapy (ART) initiation is crucial to achieve HIV viral suppression and reduce transmission. HIV-infected Chinese men who have sex with men (MSM) were less likely to initiate ART than oth...

    Authors: Yu Liu, Yuhua Ruan, Sten H. Vermund, Chandra Y. Osborn, Pingsheng Wu, Yujiang Jia, Yiming Shao and Han-Zhu Qian

    Citation: BMC Infectious Diseases 2015 15:570

    Content type: Research article

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  21. HIV infection, with an estimated prevalence be between 2 and 50 times those of the general adult population is a major health challenge for prison authorities worldwide. Since no nationwide surveillance system...

    Authors: R. Monarca, G. Madeddu, R. Ranieri, S. Carbonara, G. Leo, M. Sardo, F. Choroma, S. Casari, D. Marri, A. A. Muredda, F. A. Nava and S. Babudieri

    Citation: BMC Infectious Diseases 2015 15:562

    Content type: Research article

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  22. Gay and bisexual men (GBM) are a major risk group for HIV acquisition, yet the majority of higher-risk GBM test for HIV less often than recommended (3–6 monthly). HIV self-testing has the potential to increase...

    Authors: Muhammad S. Jamil, Garrett Prestage, Christopher K. Fairley, Kirsty S. Smith, John M. Kaldor, Andrew E. Grulich, Anna M. McNulty, Marcus Chen, Martin Holt, Damian P. Conway, Handan Wand, Phillip Keen, Colin Batrouney, Jack Bradley, Benjamin R. Bavinton, Dermot Ryan…

    Citation: BMC Infectious Diseases 2015 15:561

    Content type: Study protocol

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  23. The implementation of collaborative TB-HIV services is challenging. We, therefore, assessed TB treatment outcomes in relation to HIV infection and antiretroviral therapy (ART) among TB patients attending a pri...

    Authors: Mweete D. Nglazi, Linda-Gail Bekker, Robin Wood and Richard Kaplan

    Citation: BMC Infectious Diseases 2015 15:536

    Content type: Research article

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  24. Adolescents have gained increased attention because they are the only age group where HIV related mortality is going up. We set out to describe the level and factors associated with adherence to antiretroviral...

    Authors: Nicolette Nabukeera-Barungi, Peter Elyanu, Barbara Asire, Cordelia Katureebe, Ivan Lukabwe, Eleanor Namusoke, Joshua Musinguzi, Lynn Atuyambe and Nathan Tumwesigye

    Citation: BMC Infectious Diseases 2015 15:520

    Content type: Research article

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  25. Traditional cardiovascular disease (CVD) risk factors contribute to increase risk of CVD in people living with HIV (PLWH). Of all world regions, sub-Saharan Africa has the highest prevalence of HIV yet little ...

    Authors: Tecla M. Temu, Nicholas Kirui, Celestine Wanjalla, Alfred M. Ndungu, Jemima H. Kamano, Thomas S. Inui and Gerald S. Bloomfield

    Citation: BMC Infectious Diseases 2015 15:421

    Content type: Research article

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  26. The burden of malnutrition among HIV-infected children is not well described in sub-Saharan Africa, even though it is an important problem to take into account to guarantee appropriate healthcare for these chi...

    Authors: Julie Jesson, David Masson, Arsène Adonon, Caroline Tran, Capitoline Habarugira, Réjane Zio, Léoncie Nicimpaye, Sophie Desmonde, Goreth Serurakuba, Rosine Kwayep, Edith Sare, Tiefing Konate, Abdoulaye Nimaga, Philemon Saina, Akossiwa Kpade, Andrée Bassuka…

    Citation: BMC Infectious Diseases 2015 15:216

    Content type: Research article

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  27. Mycobacterium tuberculosis (TB) infection of the liver, known as hepatic TB, is an extrapulmonary manifestation of TB. Hepatic TB has become more prevalent, likely as a result of the human immunodeficiency virus/...

    Authors: Andrew J Hickey, Lilishia Gounder, Mahomed-Yunus S Moosa and Paul K Drain

    Citation: BMC Infectious Diseases 2015 15:209

    Content type: Research article

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  28. Truck drivers constitute an important bridging group in the HIV epidemic in Morocco. This study examined the effect of a community-based educational intervention in Morocco on HIV testing and counseling, in re...

    Authors: Hakima Himmich, Lahoucine Ouarsas, Fatima Zahra Hajouji, Caroline Lions, Perrine Roux and Patrizia Carrieri

    Citation: BMC Infectious Diseases 2015 15:208

    Content type: Research article

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  29. Hepatitis B virus (HBV) vaccine antibody response has been associated with reduced risk of AIDS or death. However, it is unknown whether HBV vaccine responsiveness is associated with improved immune reconstitu...

    Authors: Kahtonna Allen, Octavio Mesner, Anuradha Ganesan, Thomas A O’Bryan, Robert G Deiss, Brian K Agan and Jason F Okulicz

    Citation: BMC Infectious Diseases 2015 15:203

    Content type: Research article

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  30. Over the last two decades, the proportion of people who inject drugs among newly reported HIV cases in Italy has been continuously declining. This trend is reflected in the prevalence of HIV infection among pr...

    Authors: Mario Cruciani, Lucas Wiessing, Giovanni Serpelloni, Bruno Genetti, Alessandra Andreotti, Carpignano Iulia, Monica Zermiani and Barbara Suligoi

    Citation: BMC Infectious Diseases 2015 15:201

    Content type: Research article

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  31. Among people living with HIV/AIDS, illicit drug use is a risk for sub-optimal treatment outcomes. However, few studies have examined the relative contributions of different patterns of drug use on adherence to...

    Authors: Pouya Azar, Evan Wood, Paul Nguyen, Maxo Luma, Julio Montaner, Thomas Kerr and M-J Milloy

    Citation: BMC Infectious Diseases 2015 15:193

    Content type: Research article

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  32. Syphilis facilitates both HIV (human immunodeficiency virus) transmission and acquisition, reflecting the complex interplay between the two infections. Scarce information exists regarding syphilis epidemiology...

    Authors: Techalew Shimelis, Kinfe Lemma, Henock Ambachew and Endale Tadesse

    Citation: BMC Infectious Diseases 2015 15:189

    Content type: Research article

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  33. After more than a decade of establishing and expanding access to highly active antiretroviral therapy (HAART), empirical evidence on its impact on trends of opportunistic infections (OIs) associated with the d...

    Authors: John Rubaihayo, Nazarius M Tumwesigye and Joseph Konde-Lule

    Citation: BMC Infectious Diseases 2015 15:187

    Content type: Research article

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  34. We explored the impact of transient cART started during the primary HIV-infection (PHI) on the long-term immunologic and virologic response on cART resumption, by comparison with treatment initiation during th...

    Authors: Evguenia Krastinova, Remonie Seng, Jerome Lechenadec, Henri Panjo, Asma Essat, Djamila Makhloufi, Martine Obadia, Louis Bernard, Cecile Goujard and Laurence Meyer

    Citation: BMC Infectious Diseases 2015 15:178

    Content type: Research article

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  35. The causes of severe morbidity in health facilities implementing Antiretroviral Treatment (ART) programmes are poorly documented in sub-Saharan Africa. We aimed to describe severe morbidity among HIV-infected ...

    Authors: Yao Abo, Marcel Zannou Djimon, Eugène Messou, Eric Balestre, Martial Kouakou, Jocelyn Akakpo, Carin Ahouada, Nathalie de Rekeneire, François Dabis, Charlotte Lewden and Albert Minga

    Citation: BMC Infectious Diseases 2015 15:176

    Content type: Research article

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  36. In the Mitra plus study of prevention of mother-to-child transmission of HIV-1, which included 501 women in Dar es Salaam, Tanzania, triple antiretroviral therapy (ART) was given from late pregnancy throughout...

    Authors: Matilda Ngarina, Charles Kilewo, Katarina Karlsson, Said Aboud, Annika Karlsson, Gaetano Marrone, Germana Leyna, Anna Mia Ekström and Gunnel Biberfeld

    Citation: BMC Infectious Diseases 2015 15:175

    Content type: Research article

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  37. Few studies have described time-based trends of clinical and demographic characteristics of children enrolling in HIV and AIDS care and treatment services. We present findings of a study that explored time-bas...

    Authors: David Sando, Donna Spiegelman, Lameck Machumi, Mary Mwanyika-Sando, Eric Aris, Aisa Muya, Elizabeth Jackson, Till Baernighausen, Ellen Hertzmark, Guerino Chalamilla and Wafaie Fawzi

    Citation: BMC Infectious Diseases 2015 15:157

    Content type: Research article

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  38. Daily throughout 2011, about 900 new HIV infections occurred in children and 630 children died as a result of AIDS-related complications worldwide. Late diagnosis, mortality trends, causes of and risk factors ...

    Authors: Sandra Fagundes Moreira-Silva, Eliana Zandonade and Angélica Espinosa Miranda

    Citation: BMC Infectious Diseases 2015 15:155

    Content type: Research article

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  39. Increased levels of markers of systemic inflammation have been associated with serious non-AIDS events even in patients on fully suppressive antiretroviral therapy. We explored residual viremia and systemic in...

    Authors: Alejandro Arenas-Pinto, Ana Milinkovic, Dimitra Peppa, Anna McKendry, Mala Maini and Richard Gilson

    Citation: BMC Infectious Diseases 2015 15:138

    Content type: Research article

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  40. In Nigeria, reports of the outcomes of prevention of mother to child transmission of HIV (PMTCT) interventions had been limited to the MTCT rates of HIV, with no information on HIV-free survival (HFS) in the H...

    Authors: Emmanuel A Anígilájé, Othniel J Dabit, Ayodotun Olutola, Bem Ageda and Sunday A Aderibigbe

    Citation: BMC Infectious Diseases 2015 15:132

    Content type: Research article

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  41. Achieving the goal of eliminating mother-to-child HIV transmission (MTCT) necessitates increased access to antiretroviral therapy (ART) for HIV-infected pregnant women. Option B provides ART through pregnancy ...

    Authors: Adam VanDeusen, Elijah Paintsil, Thomas Agyarko-Poku and Elisa F Long

    Citation: BMC Infectious Diseases 2015 15:130

    Content type: Research article

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  42. Successful antiretroviral therapy (ART) has dramatically reduced mortality among HIV-infected children. However, there is growing concern about long-term effects associated to ART. The aim of this study was to...

    Authors: Daniel Blázquez, José Tomás Ramos-Amador, Talía Saínz, María José Mellado, Marta García-Ascaso, María Isabel De José, Pablo Rojo, María Luisa Navarro, María Ángeles Muñoz-Fernández, Jesús Saavedra, Miguel Angel Roa, Santiago Jiménez, José Beceiro, Luis Prieto, Milagros García Hortelano and María Isabel González-Tomé

    Citation: BMC Infectious Diseases 2015 15:119

    Content type: Research article

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  43. The rate of vertical HIV transmission has decreased in Brazil, but regional inequalities suggest problems in implementing control measures during pregnancy and delivery. The aims of this study were to ascertai...

    Authors: Rosa Maria Soares Madeira Domingues, Celia Landmann Szwarcwald, Paulo Roberto Borges Souza Jr and Maria do Carmo Leal

    Citation: BMC Infectious Diseases 2015 15:100

    Content type: Research article

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  44. Highly active antiretroviral therapy (HAART) has extended life expectancy and enhanced the well-being of HIV-positive individuals. Since there are concerns regarding HAART-mediated onset of cardio-metabolic di...

    Authors: Theodore A Nell, Maritza J Kruger, Dillan C Beukes, Esme Calitz, Rehana Essop and M Faadiel Essop

    Citation: BMC Infectious Diseases 2015 15:85

    Content type: Research article

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  45. People who inject drugs (PWID) are an important group at risk of blood borne infections in Poland. However, robust evidence regarding the magnitude of the problem and geographical variation is lacking, while c...

    Authors: Magdalena Rosińska, Janusz Sierosławski and Lucas Wiessing

    Citation: BMC Infectious Diseases 2015 15:83

    Content type: Research article

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  46. The HIV-1 epidemic in Slovenia, a small Central European country, has some characteristics that make it an ideal model to study HIV-1 transmission. The epidemic is predominantly affecting men who have sex with...

    Authors: Maja M Lunar, Anne-Mieke Vandamme, Janez Tomažič, Primož Karner, Tomaž D Vovko, Blaž Pečavar, Gabriele Volčanšek, Mario Poljak and Ana B Abecasis

    Citation: BMC Infectious Diseases 2015 15:65

    Content type: Research article

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  47. Several in vitro studies suggested the microRNA-29 (miRNA-29) family is involved in regulating HIV-1 and modulating the expression of interleukin (IL)-32, an anti-HIV-1 cytokine.

    Authors: Katia Monteleone, Carla Selvaggi, Giulia Cacciotti, Francesca Falasca, Ivano Mezzaroma, Gabriella D’Ettorre, Ombretta Turriziani, Vincenzo Vullo, Guido Antonelli and Carolina Scagnolari

    Citation: BMC Infectious Diseases 2015 15:51

    Content type: Research article

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  48. Penicillium marneffei disseminates hematogenously and can infect most organs, though infection leading to osteolysis is extremely rare. We describe the clinical and laboratory features, management, and outcomes o...

    Authors: Ye Qiu, Jianquan Zhang, Guangnan Liu, Xiaoning Zhong, Jingmin Deng, Zhiyi He and Bai Jing

    Citation: BMC Infectious Diseases 2015 15:47

    Content type: Research article

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COVID-19 Announcement

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.