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BMC Infectious Diseases

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Hepatitis and co-infections

Section edited by Jean-Claude Desenclos

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of hepatitis in humans as well as related molecular genetics, pathophysiology, and epidemiology

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  1. Content type: Research article

    Viral Hepatitis B is of a major public health concern globally, especially in developing countries. Expectant mothers’ knowledge of Mother-To-Child Transmission (MTCT) of the disease is significant in preventi...

    Authors: Frederick Dun-Dery, Martin Nyaaba Adokiya, Williams Walana, Ernestina Yirkyio and Juventus B. Ziem

    Citation: BMC Infectious Diseases 2017 17:416

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  2. Content type: Research article

    This Phase 3, open-label, rollover study (NCT01323244) investigated the efficacy and safety of simeprevir plus peginterferon α-2a (PegIFNα-2a) and ribavirin (RBV) in a well-characterized population of HCV geno...

    Authors: Edward J. Gane, Edwin DeJesus, Ewa Janczewska, Jacob George, Moises Diago, Mariliza Hendrique Da Silva, Henk Reesink, Igor Nikitin, Holger Hinrichsen, Stefan Bourgeois, Peter Ferenci, Umesh Shukla, Ronald Kalmeijer, Oliver Lenz, Bart Fevery, Chris Corbett…

    Citation: BMC Infectious Diseases 2017 17:389

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  3. Content type: Research article

    There is a need for validation of noninvasive alternatives to liver biopsy for the evaluation of fibrosis in children with chronic hepatitis C (CHC). The aim of this study was to evaluate the diagnostic perfor...

    Authors: Maria Pokorska-Śpiewak, Barbara Kowalik-Mikołajewska, Małgorzata Aniszewska, Magdalena Pluta and Magdalena Marczyńska

    Citation: BMC Infectious Diseases 2017 17:361

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  4. Content type: Research article

    In Japan, approximately 0.9% and 1% of the whole population are infected with HBV and HCV, respectively. Doctors from departments other than gastroenterology often order viral hepatitis tests before an invasiv...

    Authors: Naoki Yoshioka, Akihiko Okumura, Yukie Yamamoto, Katsura Yamaguchi, Atsuro Kaga, Kentaro Yamada, Takuya Hirosaki, Daisuke Ishikawa, Shin Kunii, Kazumasa Watanabe, Setsuo Utsunomiya, Kazuhiko Hayashi, Masatoshi Ishigami, Hidemi Goto and Yoshiki Hirooka

    Citation: BMC Infectious Diseases 2017 17:330

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  5. Content type: Research article

    Hepatitis C virus (HCV) infections have increased during the past decade but little is known about geographic clustering patterns.

    Authors: Thomas J. Stopka, Michael A. Goulart, David J. Meyers, Marga Hutcheson, Kerri Barton, Shauna Onofrey, Daniel Church, Ashley Donahue and Kenneth K. H. Chui

    Citation: BMC Infectious Diseases 2017 17:294

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  6. Content type: Research article

    Hepatitis C infection is a major public health concern in low- and middle-income countries where an estimated 71.1 million individuals are living with chronic infection. The World Health Organization (WHO) has...

    Authors: Alessandra Berto, Jeremy Day, Nguyen Van Vinh Chau, Guy E. Thwaites, Ngoc Nghiem My, Stephen Baker and Thomas C. Darton

    Citation: BMC Infectious Diseases 2017 17:260

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  7. Content type: Research article

    In chronic hepatitis C, the fibrosis progression rates are extremely variable and can be influenced by factors associated with the host, virus and environment. Among the associated metabolic factors, hepatic s...

    Authors: Mariana Cavalheiro Magri, Thamiris Vaz Gago Prata, Caroline Manchiero, Bianca Peixoto Dantas, Celso Carmo Mazza and Fátima Mitiko Tengan

    Citation: BMC Infectious Diseases 2017 17:235

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  8. Content type: Research article

    Hepatitis C virus (HCV) infection is a pandemic causing disease; more than 185 million people are infected worldwide. An HCV antibody (Ab) prevalence of 6.0% was estimated in Central African countries. The stu...

    Authors: Mwumvaneza Mutagoma, Helene Balisanga, Dieudonné Sebuhoro, Aimable Mbituyumuremyi, Eric Remera, Samuel S. Malamba, David J. Riedel and Sabin Nsanzimana

    Citation: BMC Infectious Diseases 2017 17:167

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  9. Content type: Research article

    HCV transmission remains high in people who inject drugs (PWID) in Montréal. New direct-acting antivirals (DAAs), highly effective and more tolerable than previous regimens, make a “Treatment as Prevention” (T...

    Authors: Anthony Cousien, Pascale Leclerc, Carole Morissette, Julie Bruneau, Élise Roy, Viet Chi Tran, Yazdan Yazdanpanah and Joseph Cox

    Citation: BMC Infectious Diseases 2017 17:162

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  10. Content type: Research article

    The sodium taurocholate co-transporting polypeptide, encoded by SLC10A1, was identified as a functional receptor for hepatitis B virus (HBV). The objective of this study was to determine if there was an associ...

    Authors: Sayeh Ezzikouri, Hajar Chihab, Abdellah Elhabazi, Lahcen Wakrim and Soumaya Benjelloun

    Citation: BMC Infectious Diseases 2017 17:99

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  11. Content type: Research article

    Cocaine and crack use has been associated with HIV and HCV infections, but its consequences on HCV progression have not been well established. We analyzed the impact of cocaine/crack use on liver fibrosis prog...

    Authors: Valérie Martel-Laferrière, Roy Nitulescu, Joseph Cox, Curtis Cooper, Mark Tyndall, Danielle Rouleau, Sharon Walmsley, Leo Wong and Marina B. Klein

    Citation: BMC Infectious Diseases 2017 17:80

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  12. Content type: Research article

    Toll like receptors (TLRs) play an important role in innate immunity and various studies suggest that TLRs play a crucial role in pathogenesis of hepatitis B virus (HBV) infection. The present study aims in lo...

    Authors: Dipanwita Das, Isha Sengupta, Neelakshi Sarkar, Ananya Pal, Debraj Saha, Manikankana Bandopadhyay, Chandrima Das, Jimmy Narayan, Shivaram Prasad Singh, Sekhar Chakrabarti and Runu Chakravarty

    Citation: BMC Infectious Diseases 2017 17:76

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  13. Content type: Research article

    There is limited evidence for the effectiveness of daclatasvir in patients whose hepatitis C threatens their life expectancy. The Named Patient Program in Europe included patients with advanced chronic hepatit...

    Authors: Jim Young, Nina Weis, Harald Hofer, William Irving, Ola Weiland, Emiliano Giostra, Juan Manuel Pascasio, Lluis Castells, Martin Prieto, Roelien Postema, Cinira Lefevre, David Evans, Heiner C. Bucher and Jose Luis Calleja

    Citation: BMC Infectious Diseases 2017 17:45

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  14. Content type: Research article

    Rwanda is a central African country with about 12 million inhabitants. The 1994 genocide against the Tutsi destroyed much of the infrastructure, including the health system. Although this has improved signific...

    Authors: Theogene Twagirumugabe, Gatare Swaibu, Timothy David Walker, Magnus Lindh, Jean Bosco Gahutu, Tomas Bergström and Heléne Norder

    Citation: BMC Infectious Diseases 2017 17:32

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  15. Content type: Research article

    The concentrations of hepatitis B virus (HBV) DNA and surface antigen (HBsAg) are two critical virological variables to be monitored in chronic hepatitis B. HBsAg is derived from the HBV genome. Thus, higher H...

    Authors: Chao-Wei Hsu, Kung-Hao Liang, Chih-Lang Lin, Tong-Hong Wang and Chau-Ting Yeh

    Citation: BMC Infectious Diseases 2017 17:9

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  16. Content type: Research article

    The existing seroepidemiological data on viral hepatitis in Ethiopia showed a wide variation in prevalence pattern and the clinical and public health burden have been underestimated. The aim of this systematic...

    Authors: Yeshambel Belyhun, Melanie Maier, Andargachew Mulu, Ermias Diro and Uwe Gerd Liebert

    Citation: BMC Infectious Diseases 2016 16:761

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    The Erratum to this article has been published in BMC Infectious Diseases 2017 17:114

  17. Content type: Research article

    As one of the causative agents of viral hepatitis, hepatitis E virus (HEV) has gained public health attention globally. HEV epidemics occur in developing countries, associated with faecal contamination of wate...

    Authors: Ashish C. Shrestha, Robert L. P. Flower, Clive R. Seed, Manita Rajkarnikar, Shrawan K. Shrestha, Uru Thapa, Veronica C. Hoad and Helen M. Faddy

    Citation: BMC Infectious Diseases 2016 16:707

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  18. Content type: Research article

    Studies have shown that the immunosuppression induced by the human immunodeficiency virus (HIV) accelerates the natural history of liver disease associated with hepatitis C virus (HCV), with 3- to 5-fold highe...

    Authors: Fatima Mitiko Tengan, Karim Yakub Ibrahim, Bianca Peixoto Dantas, Caroline Manchiero, Mariana Cavalheiro Magri and Wanderley Marques Bernardo

    Citation: BMC Infectious Diseases 2016 16:663

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  19. Content type: Research article

    In the last decade hepatitis E virus (HEV) is increasingly recognized as a cause of acute viral hepatitis in developed countries. HEV is transmitted via the fecal-oral route. In countries like the Netherlands,...

    Authors: S. Sadik, G. G. C. van Rijckevorsel, M. S. van Rooijen, G. J. B. Sonder and S. M. Bruisten

    Citation: BMC Infectious Diseases 2016 16:659

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  20. Content type: Research article

    Hepatocellular Carcinoma (HCC) is one of the commonest cancers in Central Africa, a region with the unusual peculiarity to be hyperendemic for infections with Hepatitis B, C and D viruses. However, data estima...

    Authors: Marie Atsama Amougou, Dominique Noah Noah, Paul Fewou Moundipa, Pascal Pineau and Richard Njouom

    Citation: BMC Infectious Diseases 2016 16:647

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