Hepatitis and co-infections

Section edited by Jean-Claude Desenclos

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of hepatitis in humans as well as related molecular genetics, pathophysiology, and epidemiology

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  1. Research article

    Co-infection of Schistosoma mansoni/hepatitis C virus and their associated factors among adult individuals living in fishing villages, north-western Tanzania

    Schistosoma mansoni and Hepatitis C virus (HCV) are co-existence in sub-Saharan Africa and co-infection is common among humans population. The immunological responses characterized wit...

    Humphrey D. Mazigo, Stella Kepha, Godfrey M. Kaatano and Safari M. Kinung’hi

    BMC Infectious Diseases 2017 17:668

    Published on: 10 October 2017

  2. Research article

    Prevalence and risk factors of hepatitis B infection among mothers and children with hepatitis B infected mother in upper Dolpa, Nepal

    Hepatitis B Virus (HBV) infection is a worldwide public health problem. In Nepal, the prevalence of HBV is found to be low (0.9%), although high prevalence (≥8%) of HBV infection is depicted among subgroup/pop...

    Purusotam Raj Shedain, Madhu Dixit Devkota, Megha Raj Banjara, Huang Ling and Subash Dhital

    BMC Infectious Diseases 2017 17:667

    Published on: 10 October 2017

  3. Research article

    Angiopoietin-like protein as a novel marker for liver fibrosis in chronic hepatitis B patients with normal to minimally raised ALT

    For hepatitis B patients who do not meet the treatment criteria recommended by guidelines, therapy decisions depend on hepatic histology. Angiopoietin-like protein 2 (Angptl2) is a mediator of chronic inflamma...

    Yongqiong Deng, Hong Zhao, Jiyuan Zhou, Linlin Yan and Guiqiang Wang

    BMC Infectious Diseases 2017 17:650

    Published on: 29 September 2017

  4. Research article

    Hepatitis B virus and HIV co-infection among pregnant women in Rwanda

    Hepatitis B virus (HBV) affects people worldwide but the local burden especially in pregnant women and their new born babies is unknown. In Rwanda HIV-infected individuals who are also infected with HBV are su...

    Mwumvaneza Mutagoma, Helene Balisanga, Samuel S. Malamba, Dieudonné Sebuhoro, Eric Remera, David J. Riedel, Steve Kanters and Sabin Nsanzimana

    BMC Infectious Diseases 2017 17:618

    Published on: 11 September 2017

  5. Research article

    Molecular characterization of hepatitis B virus in Vietnam

    Hepatitis B virus (HBV) infection is a major public health problem globally. HBV genotypes and subgenotypes influence disease transmission, progression, and treatment outcome. A study was conducted among treat...

    Thi Ton Taht Bui, Tan Thanh Tran, My Ngoc Nghiem, Pierre Rahman, Thi Thanh Thanh Tran, Man Nguyen Huy Dinh, Manh Hung Le, Van Vinh Chau Nguyen, Guy Thwaites and Motiur Rahman

    BMC Infectious Diseases 2017 17:601

    Published on: 31 August 2017

  6. Research article

    Prevalence of hepatitis B in people living with HIV/AIDS in Latin America and the Caribbean: a systematic review and meta-analysis

    Hepatitis B virus (HBV) infection is a major cause of chronic liver disease worldwide. In immunocompromised patients, the chronicity rates of HBV infection are higher, but the rates of hepatitis Be antigen (HB...

    Fatima Mitiko Tengan, Edson Abdala, Marisa Nascimento, Wanderley Marques Bernardo and Antonio Alci Barone

    BMC Infectious Diseases 2017 17:587

    Published on: 24 August 2017

  7. Case report

    Hepatitis B reactivation characterized by HBsAg negativity and anti-HbsAg antibodies persistence in haematopoietic stem cell transplanted patient after lamivudine withdrawal

    HBV reactivation is associated with high mortality rates in hematopoietic stem cell transplantation (HSCT) and prophylactic lamivudine (LMV) treatment is suggested to prevent this phenomenon. However, the dura...

    C. Cerva, G. Maffongelli, V. Svicher, R. Salpini, L. Colagrossi, A. Battisti, B. Mariotti, R. Cerretti, L. Cudillo and L. Sarmati

    BMC Infectious Diseases 2017 17:566

    Published on: 15 August 2017

  8. Research article

    Genotypes of hepatitis a virus in Turkey: first report and clinical profile of children infected with sub-genotypes IA and IIIA

    Hepatitis A virus (HAV) is a food and water-borne virus causing clinical (mainly hepatitis) and subclinical disease in humans. It is important to characterize circulating strains of HAV in order to prevent HAV...

    Huseyin Yilmaz, Asiye Karakullukcu, Nuri Turan, Utku Y. Cizmecigil, Aysun Yilmaz, Ayse A. Ozkul, Ozge Aydin, Alper Gunduz, Mahmut Mete, Fadile Y. Zeyrek, Taner T. Kirazoglu, Juergen A. Richt and Bekir Kocazeybek

    BMC Infectious Diseases 2017 17:561

    Published on: 11 August 2017

  9. Research article

    Strategies for the prevention of perinatal hepatitis B transmission in a marginalized population on the Thailand-Myanmar border: a cost-effectiveness analysis

    Data on the cost effectiveness of hepatitis B virus (HBV) screening and vaccination strategies for prevention of vertical transmission of HBV in resource limited settings is sparse.

    Angela Devine, Rebecca Harvey, Aung Myat Min, Mary Ellen T. Gilder, Moo Koh Paw, Joy Kang, Isabella Watts, Borimas Hanboonkunupakarn, François Nosten and Rose McGready

    BMC Infectious Diseases 2017 17:552

    Published on: 9 August 2017

  10. Research article

    Modelling the burden of hepatitis C infection among people who inject drugs in Norway, 1973–2030

    Lack of Hepatitis C virus (HCV) incidence data in (Norwegian) high-risk groups impedes the ability to make informed decisions on prevention measures. Thus we rely on modelling to estimate the incidence and bur...

    Hinta Meijerink, Richard A White, Astrid Løvlie, Birgitte Freiesleben de Blasio, Olav Dalgard, Ellen J. Amundsen, Espen Melum and Hilde Kløvstad

    BMC Infectious Diseases 2017 17:541

    Published on: 3 August 2017

  11. Research article

    Age-standardized mortality rates related to viral hepatitis in Brazil

    Liver-related mortality has been increasing worldwide. We aimed to estimate the age-standardized mortality rates from viral hepatitis in Brazil.

    Hugo Perazzo, Antonio G Pacheco, Paula M Luz, Rodolfo Castro, Chris Hyde, Juliana Fittipaldi, Caroline Rigolon, Sandra W Cardoso, Beatriz Grinsztejn and Valdiléa G Veloso

    BMC Infectious Diseases 2017 17:527

    Published on: 31 July 2017

  12. Research article

    Hepatitis a virus genotypes and strains from an endemic area of Europe, Bulgaria 2012–2014

    Hepatitis A virus (HAV) infection is endemic in Eastern European and Balkan region countries. In 2012, Bulgaria showed the highest rate (67.13 cases per 100,000) in Europe. Nevertheless, HAV genotypes and stra...

    Roberto Bruni, Stefania Taffon, Michele Equestre, Eleonora Cella, Alessandra Lo Presti, Angela Costantino, Paola Chionne, Elisabetta Madonna, Elitsa Golkocheva-Markova, Diljana Bankova, Massimo Ciccozzi, Pavel Teoharov and Anna Rita Ciccaglione

    BMC Infectious Diseases 2017 17:497

    Published on: 14 July 2017

  13. Research article

    Risk factors, person, place and time characteristics associated with Hepatitis E Virus outbreak in Napak District, Uganda

    Hepatitis E is self-limiting, but can cause death in most at risk groups like pregnant women and those with preexisting acute liver disease. In developing countries it presents as epidemic, in 2014 Hepatitis E...

    Geofrey Amanya, Samuel Kizito, Immaculate Nabukenya, Joan Kalyango, Collins Atuheire, Hellen Nansumba, Stephen Akena Abwoye, Denis Nixon Opio, Edrisa Kibuuka and Charles Karamagi

    BMC Infectious Diseases 2017 17:451

    Published on: 26 June 2017

  14. Research article

    Early experiences from one of the first treatment programs for chronic hepatitis B in sub-Saharan Africa

    Treatment for chronic hepatitis B (CHB) is virtually absent in sub-Saharan Africa. Here we present early experiences from a pilot program for treatment of CHB in Ethiopia.

    Hanna Aberra, Hailemichael Desalegn, Nega Berhe, Girmay Medhin, Kathrine Stene-Johansen, Svein Gunnar Gundersen and Asgeir Johannessen

    BMC Infectious Diseases 2017 17:438

    Published on: 19 June 2017

  15. Research article

    Adherence to response-guided pegylated interferon and ribavirin for people who inject drugs with hepatitis C virus genotype 2/3 infection: the ACTIVATE study

    The aims of this analysis were to investigate treatment completion and adherence among people with ongoing injecting drug use or receiving opioid substitution therapy (OST) in a study of response-guided therap...

    Evan B. Cunningham, Behzad Hajarizadeh, Olav Dalgard, Janaki Amin, Margaret Hellard, Graham R Foster, Philip Bruggmann, Brian Conway, Markus Backmund, Geert Robaeys, Tracy Swan, Philippa S. Marks, Sophie Quiene, Tanya L Applegate, Martin Weltman, David Shaw…

    BMC Infectious Diseases 2017 17:420

    Published on: 13 June 2017

  16. Research article

    Assessing the knowledge of expectant mothers on mother–to-child transmission of viral hepatitis B in Upper West region of Ghana

    Viral Hepatitis B is of a major public health concern globally, especially in developing countries. Expectant mothers’ knowledge of Mother-To-Child Transmission (MTCT) of the disease is significant in preventi...

    Frederick Dun-Dery, Martin Nyaaba Adokiya, Williams Walana, Ernestina Yirkyio and Juventus B. Ziem

    BMC Infectious Diseases 2017 17:416

    Published on: 12 June 2017

  17. Research article

    Simeprevir with peginterferon α-2a/ribavirin for chronic hepatitis C virus genotype 1 infection in treatment-experienced patients: an open-label, rollover study

    This Phase 3, open-label, rollover study (NCT01323244) investigated the efficacy and safety of simeprevir plus peginterferon α-2a (PegIFNα-2a) and ribavirin (RBV) in a well-characterized population of HCV geno...

    Edward J. Gane, Edwin DeJesus, Ewa Janczewska, Jacob George, Moises Diago, Mariliza Hendrique Da Silva, Henk Reesink, Igor Nikitin, Holger Hinrichsen, Stefan Bourgeois, Peter Ferenci, Umesh Shukla, Ronald Kalmeijer, Oliver Lenz, Bart Fevery, Chris Corbett…

    BMC Infectious Diseases 2017 17:389

    Published on: 2 June 2017

  18. Research article

    Novel serum biomarkers modified by the body mass index z-score for the detection of liver fibrosis and steatosis in children with chronic hepatitis C

    There is a need for validation of noninvasive alternatives to liver biopsy for the evaluation of fibrosis in children with chronic hepatitis C (CHC). The aim of this study was to evaluate the diagnostic perfor...

    Maria Pokorska-Śpiewak, Barbara Kowalik-Mikołajewska, Małgorzata Aniszewska, Magdalena Pluta and Magdalena Marczyńska

    BMC Infectious Diseases 2017 17:361

    Published on: 23 May 2017

  19. Research article

    Promoting notification and linkage of HBs antigen and anti-HCV antibody-positive patients through hospital alert system

    In Japan, approximately 0.9% and 1% of the whole population are infected with HBV and HCV, respectively. Doctors from departments other than gastroenterology often order viral hepatitis tests before an invasiv...

    Naoki Yoshioka, Akihiko Okumura, Yukie Yamamoto, Katsura Yamaguchi, Atsuro Kaga, Kentaro Yamada, Takuya Hirosaki, Daisuke Ishikawa, Shin Kunii, Kazumasa Watanabe, Setsuo Utsunomiya, Kazuhiko Hayashi, Masatoshi Ishigami, Hidemi Goto and Yoshiki Hirooka

    BMC Infectious Diseases 2017 17:330

    Published on: 8 May 2017

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