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Bacterial and fungal diseases

Section edited by Ivan FN Hung, Jorge Garbino and Kelvin To

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of bacterial and fungal diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section includes studies relating to antibiotic resistance and healthcare-associated infections.

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  1. Klebsiella variicola and K. quasipneumoniae are new species distinguishable from K. pneumoniae but they are often misidentified as K. pneumoniae in clinical settings. Several reports have demonstrated the possibi...

    Authors: Kazuo Imai, Noriomi Ishibashi, Masahiro Kodana, Norihito Tarumoto, Jun Sakai, Toru Kawamura, Shinichi Takeuchi, Yoshitada Taji, Yasuhiro Ebihara, Kenji Ikebuchi, Takashi Murakami, Takuya Maeda, Kotaro Mitsutake and Shigefumi Maesaki

    Citation: BMC Infectious Diseases 2019 19:946

    Content type: Research article

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  2. In recent years, the number of infective endocarditis (IE) cases associated with injection drug use has increased. Clinical guidelines suggest deferring surgery for IE in people who inject drugs (PWID) due to ...

    Authors: David Goodman-Meza, Robert E. Weiss, Sebastián Gamboa, Abel Gallegos, Alex A. T. Bui, Matthew B. Goetz, Steven Shoptaw and Raphael J. Landovitz

    Citation: BMC Infectious Diseases 2019 19:918

    Content type: Research article

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  3. Initiating early effective antimicrobial therapy is the most important intervention demonstrated to decrease mortality in patients with gram-negative bacteremia with sepsis. Rapid MIC-based susceptibility resu...

    Authors: Gerald Elliott, Michael Malczynski, Viktorjia O. Barr, Doaa Aljefri, David Martin, Sarah Sutton, Teresa R. Zembower, Michael Postelnick and Chao Qi

    Citation: BMC Infectious Diseases 2019 19:942

    Content type: Research article

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  4. Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has been rapidly developed and widely used as an analytical technique in clinical laboratories with high accuracy in ...

    Authors: Ying Li, Mingzhu Shan, Zuobin Zhu, Xuhua Mao, Mingju Yan, Ying Chen, Qiuju Zhu, Hongchun Li and Bing Gu

    Citation: BMC Infectious Diseases 2019 19:941

    Content type: Research article

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  5. Bacillus anthracis causes a highly lethal infectious disease primarily due to toxin-mediated injury. Antibiotics are no longer effective to treat the accumulation of anthrax toxin, thereby new strategies of antib...

    Authors: Siping Xiong, Tingting Zhou, Feng Zheng, Xudong Liang, Yongping Cao, Chunhui Wang, Zhengqin Feng, Qi Tang and Jin Zhu

    Citation: BMC Infectious Diseases 2019 19:940

    Content type: Research article

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  6. Invasive candidiasis (IC) is the most common invasive fungal infection. The epidemiology of IC in hospitalized patients has been widely investigated in many metropolitan cities; however, little information fro...

    Authors: Zhang-rui Zeng, Gang Tian, Yin-huan Ding, Kui Yang, Jin-bo Liu and Jian Deng

    Citation: BMC Infectious Diseases 2019 19:939

    Content type: Research article

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  7. Viral bronchiolitis is the most common cause of respiratory failure requiring invasive ventilation in young children. Bacterial co-infections may complicate and prolong paediatric intensive care unit (PICU) st...

    Authors: Hanke M. G. Wiegers, Lisa van Nijen, Job B. M. van Woensel, Reinout A. Bem, Menno D. de Jong and Job C. J. Calis

    Citation: BMC Infectious Diseases 2019 19:938

    Content type: Research article

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  8. The sepsis-induced immunodepression contributes to impaired clinical outcomes of various stress conditions. This syndrome is well documented and characterized by attenuated function of innate and adaptive immu...

    Authors: Didier Payen, Valerie Faivre, Jordi Miatello, Jenneke Leentjens, Caren Brumpt, Pierre Tissières, Claire Dupuis, Peter Pickkers and Anne Claire Lukaszewicz

    Citation: BMC Infectious Diseases 2019 19:931

    Content type: Research article

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  9. Endemic presence of Klebsiella pneumoniae resistant to carbapenem in Italy has been due principally to the clonal expansion of CC258 isolates; however, recent studies suggest an ongoing epidemiological change in ...

    Authors: Teresa Fasciana, Bernardina Gentile, Maria Aquilina, Andrea Ciammaruconi, Chiara Mascarella, Anna Anselmo, Antonella Fortunato, Silvia Fillo, Giancarlo Petralito, Florigio Lista and Anna Giammanco

    Citation: BMC Infectious Diseases 2019 19:928

    Content type: Research article

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  10. Capnocytophaga canimorsus is a gram-negative bacterium and an oral commensal in dogs and cats, but occasionally causes serious infections in humans. Septicemia is one of the most fulminant forms, but diagnosis of...

    Authors: Jun Sakai, Kazuhito Imanaka, Masahiro Kodana, Kana Ohgane, Susumu Sekine, Kei Yamamoto, Yusuke Nishida, Toru Kawamura, Takahiro Matsuoka, Shigefumi Maesaki, Hideaki Oka and Hideaki Ohno

    Citation: BMC Infectious Diseases 2019 19:927

    Content type: Case report

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  11. Pertussis causes severe disease in young unvaccinated infants, with preterms potentially at highest risk. We studied pertussis in hospitalized infants as related to gestational age (GA) and vaccination history.

    Authors: Nicoline A. T. van der Maas, Elisabeth A. M. Sanders, Florens G. A. Versteegh, Albertine Baauw, Anneke Westerhof and Hester E. de Melker

    Citation: BMC Infectious Diseases 2019 19:919

    Content type: Research article

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  12. Cyst infection is a prevalent complication in autosomal dominant polycystic kidney disease (ADPKD) patients, however therapeutic and diagnostic approaches towards this condition remain unclear. The confirmatio...

    Authors: Laura Onuchic, Victor Augusto Hamamoto Sato, Precil Diego Miranda de Menezes Neves, Bruno Eduardo Pedroso Balbo, Antônio Abel Portela-Neto, Fernanda Trani Ferreira, Elieser Hitoshi Watanabe, Andreia Watanabe, Maria Cláudia Stockler de Almeida, Leonardo de Abreu Testagrossa, Pedro Renato Chocair and Luiz Fernando Onuchic

    Citation: BMC Infectious Diseases 2019 19:911

    Content type: Case report

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  13. Antibiotic resistance is rising at disturbing rates and contributes to the deaths of millions of people yearly. Antibiotic resistant infections disproportionately affect those with immunocompromising condition...

    Authors: Emily R. Ko, Casandra W. Philipson, Thomas W. Burke, Regina Z. Cer, Kimberly A. Bishop-Lilly, Logan J. Voegtly, Ephraim L. Tsalik, Christopher W. Woods, Danielle V. Clark and Kevin L. Schully

    Citation: BMC Infectious Diseases 2019 19:905

    Content type: Case report

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  14. Acute Q fever usually presents as a nonspecific febrile illness, and its occurrence is rapidly increasing in South Korea. This study investigated the clinical characteristics of acute Q fever patients in South...

    Authors: Jung Yeon Heo, Young Wha Choi, Eun Jin Kim, Seung Hun Lee, Seung Kwan Lim, Seon Do Hwang, Ju Young Lee and Hye Won Jeong

    Citation: BMC Infectious Diseases 2019 19:903

    Content type: Research article

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  15. Carbapenem resistance among Acinetobacter species has become a life-threatening problem. As a last resort in the treatment of gram-negative bacteria infection, resistance to colistin is also a serious problem. Th...

    Authors: Si Li, Xiaonv Duan, Yuan Peng and Yongyu Rui

    Citation: BMC Infectious Diseases 2019 19:900

    Content type: Research article

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  16. Several reports designate the recent increase in community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) nasal carriage. Because of the scanty information regarding the nasal carriage sate of MRS...

    Authors: Elham Ahmadi, Mohammad Khojasteh, Seyed Mohammad Mortazavi, Fatemeh Khan-Mohammadi, Ali Kazemnia, Javad Beheshtipour and Mahdieh Raeeszadeh

    Citation: BMC Infectious Diseases 2019 19:899

    Content type: Research article

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  17. Salmonella infection poses significant public health threat globally, especially in resource-limited countries. Emergence and spread of antibiotic resistant strains to fluoroquinolones have led to treatment failu...

    Authors: Godfred Acheampong, Michael Owusu, Alex Owusu-Ofori, Isaac Osei, Nimako Sarpong, Augustina Sylverken, Hung-Jui Kung, Shu-Ting Cho, Chih-Horng Kuo, Se Eun Park, Florian Marks, Yaw Adu-Sarkodie and Ellis Owusu-Dabo

    Citation: BMC Infectious Diseases 2019 19:898

    Content type: Research article

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  18. The impact of animals sources of food as a possible reservoir for extended-spectrum β-lactamase (ESBL) - Producing E. coli, and the dissemination of such strains into the food production chain need to be asses...

    Authors: Mengistu Abayneh, Getnet Tesfaw, Kifle Woldemichael, Moti Yohannis and Alemseged Abdissa

    Citation: BMC Infectious Diseases 2019 19:897

    Content type: Research article

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  19. Neonatal listeriosis is a rare but severe disease manifesting as septicemia and central nervous system (CNS) infections with a high fatality rate of around 20 to 30%. Whole genome sequencing (WGS) is a promisi...

    Authors: Lijuan Luo, Xi Chen, Michael Payne, Xiaolong Cao, Yan Wang, Jie Zhang, Jianping Deng, Hong Wang, Zhengdong Zhang, Qun Li, Ruiting Lan and Changyun Ye

    Citation: BMC Infectious Diseases 2019 19:893

    Content type: Case report

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  20. The aim of this letter was to point out some methodological concerns about an article written by Shi et al. and published in the journal. There is an increasing trend in the isolation of Methicillin-susceptible S...

    Authors: Herney Andrés García-Perdomo and Jessica Fernanda Toro Maldonado

    Citation: BMC Infectious Diseases 2019 19:892

    Content type: Correspondence

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  21. Arthroscopic partial meniscectomy is a common procedure in orthopedic practice. Infections are uncommon complications of this procedure with an incidence rate of 0,01% - 3,4%. Staphylococcus spp are the predomina...

    Authors: Giovanni Balato, Tiziana Ascione, Paolino Iorio, Cristiano De Franco, Vincenzo De Matteo, Alessio D’Addona, Nicola Tammaro and Achille Pellegrino

    Citation: BMC Infectious Diseases 2019 19:887

    Content type: Case report

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  22. There have been no reports regarding the molecular characteristics, virulence features, and antibiotic resistance profiles of Staphylococcus aureus (S. aureus) from Hainan, the southernmost province of China.

    Authors: Xuehan Li, Tao Huang, Kai Xu, Chenglin Li and Yirong Li

    Citation: BMC Infectious Diseases 2019 19:873

    Content type: Research article

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  23. Pandoraea species is a newly described genus, which is multidrug resistant and difficult to identify. Clinical isolates are mostly cultured from cystic fibrosis (CF) patients. CF is a rare disease in China, which...

    Authors: Chuanzhong Lin, Ning Luo, Qiang Xu, Jianjun Zhang, Mengting Cai, Guanhao Zheng and Ping Yang

    Citation: BMC Infectious Diseases 2019 19:869

    Content type: Case report

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  24. The classic Lemierre’s syndrome refers to a septic thrombosis of the internal jugular vein, usually caused by a Fusobacterium necrophorum infection starting in the oral cavity, and typically complicated by pulmon...

    Authors: Marie-Eva Laurencet, Sarah Rosset--Zufferey and Jacques Schrenzel

    Citation: BMC Infectious Diseases 2019 19:868

    Content type: Case report

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  25. While Legionella is a common cause of pneumonia, extrapulmonary infections like arthritis are scarce. Here, we describe a case of monoarthritis due to Legionella bozemanii, with no history of pneumonia. We provid...

    Authors: Marine Ibranosyan, Laetitia Beraud, Hélène Lemaire, Anne-Gaëlle Ranc, Christophe Ginevra, Sophie Jarraud and Ghislaine Descours

    Citation: BMC Infectious Diseases 2019 19:864

    Content type: Case report

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  26. Invasive meningococcal disease (IMD) presenting with meningitis causes significant mortality and morbidity. Suppurative complications of serogroup B meningococcal sepsis are rare and necessitate urgent multidi...

    Authors: Ciara O’Connor, Aedin Collins, Eilish Twomey, Conor Hensey, John Caird and Patrick J. Gavin

    Citation: BMC Infectious Diseases 2019 19:863

    Content type: Case report

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  27. Idiopathic CD4 lymphocytopenia (ICL) is a rare clinical disease with relative CD4 deficiency in the absence of HIV infection. The pathogenicity of ICL is poorly understood with an unclear incidence rate in the...

    Authors: Christina S. Thornton, Oscar Larios, Jennifer Grossman, Thomas P. Griener and Steven Vaughan

    Citation: BMC Infectious Diseases 2019 19:862

    Content type: Case report

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  28. Exposure to blacklegged ticks Ixodes scapularis that transmit pathogens is thought to occur peri-domestically. However, the locations where people most frequently encounter infected ticks are not well characteriz...

    Authors: Ilya R. Fischhoff, Sarah E. Bowden, Felicia Keesing and Richard S. Ostfeld

    Citation: BMC Infectious Diseases 2019 19:861

    Content type: Research article

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    The Correction to this article has been published in BMC Infectious Diseases 2019 19:1035

  29. Enhanced surveillance for confirmed cases of invasive meningococcal disease (IMD) was introduced in the Netherlands in 2003, in which reference laboratory data (NRLBM) are linked with notification data (OSIRIS...

    Authors: Diederik A. H. Brandwagt, Arie van der Ende, Wilhelmina L. M. Ruijs, Hester E. de Melker and Mirjam J. Knol

    Citation: BMC Infectious Diseases 2019 19:860

    Content type: Research article

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  30. Between January 2015 and July 2017, we investigated the frequency of carbapenem resistant Acinetobacter baumannii (CRAB) and carbapenem resistant Pseudomonas aeruginosa (CRPA) at the Mulago Hospital intensive car...

    Authors: Dickson Aruhomukama, Christine F. Najjuka, Henry Kajumbula, Moses Okee, Gerald Mboowa, Ivan Sserwadda, Richard Mayanja, Moses L. Joloba and David P. Kateete

    Citation: BMC Infectious Diseases 2019 19:853

    Content type: Research article

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  31. To determine, from October 2010 to October 2018, the epidemiology of Deep Neck Infections (DNIs), regarding the detection, the identification and the susceptibility to antimicrobials of causative microorganism...

    Authors: Despoina Beka, Vasileios A. Lachanas, Stergios Doumas, Stelios Xytsas, Anastasios Kanatas, Efi Petinaki and Charalampos Skoulakis

    Citation: BMC Infectious Diseases 2019 19:850

    Content type: Research article

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  32. Salmonella outbreaks in childcare facilities are relatively rare, most often occurring secondary to contaminated food products or poor infection control practices. We report an outbreak of Salmonella Saintpaul at...

    Authors: Rachel M. Thomson, Hazel J. Henderson and Alison Smith-Palmer

    Citation: BMC Infectious Diseases 2019 19:847

    Content type: Research article

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  33. Cryptococcal meningitis is most commonly found in HIV-infected patients. In HIV-negative patients, its low incidence can lead to prolonged time to diagnosis. Detailed case reports of chronic cryptococcal menin...

    Authors: Alex Wagemakers, Cornelis Willem Ang, Ferry Hagen, Joost Cornelis Johannes Bot, Marije Kristianne Bomers, Marieke Christine Visser and Karin van Dijk

    Citation: BMC Infectious Diseases 2019 19:846

    Content type: Case report

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  34. The purposes of this study were to determine the incidence of central and peripheral venous catheter-related bacteraemias, the relationship between the suspected and final confirmed bacteraemia origins, and th...

    Authors: Jose Manuel Ruiz-Giardin, Iciar Ochoa Chamorro, Laura Velázquez Ríos, Jeronimo Jaqueti Aroca, Maria Isabel García Arata, Juan Víctor SanMartín López and Marta Guerrero Santillán

    Citation: BMC Infectious Diseases 2019 19:841

    Content type: Research article

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  35. Moraxella nonliquefaciens is a usually non-pathogenic biofilm-producing Gram-negative coccobacillus which may colonize the upper respiratory tract, rarely causing invasive disease. Although very rare, bloodstream...

    Authors: Carlos L. Correa-Martínez, Kerstin K. Rauwolf, Franziska Schuler, Miriam Füller, Stefanie Kampmeier and Andreas H. Groll

    Citation: BMC Infectious Diseases 2019 19:836

    Content type: Case report

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  36. Increasing number of hospitalized children with community acquired pneumonia (CAP) is co-detected with Mycoplasma pneumoniae (Mp). The clinical characteristics and impact of Mp co-detected with other bacterial an...

    Authors: Meng-chuan Zhao, Le Wang, Fang-zhou Qiu, Li Zhao, Wei-wei Guo, Shuo Yang, Zhi-shan Feng and Gui-xia Li

    Citation: BMC Infectious Diseases 2019 19:835

    Content type: Research article

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  37. Persistent symptoms attributed to Lyme borreliosis often include self-reported cognitive impairment. However, it remains unclear whether these symptoms can be substantiated by objective cognitive testing.

    Authors: Anneleen Berende, Joost Agelink van Rentergem, Andrea W. M. Evers, Hadewych J. M. ter Hofstede, Fidel J. Vos, Bart Jan Kullberg and Roy P. C. Kessels

    Citation: BMC Infectious Diseases 2019 19:833

    Content type: Research article

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  38. Whether past history of solid stage I/II inactive cancer has an impact on 28-day mortality of sepsis remains unclear. We aimed to determine the impact of history of stage I or II solid tumor malignancy in comp...

    Authors: George Dimοpoulos, Nikoletta Rovina, Maria Patrani, Eleni Antoniadou, Dimitrios Konstantonis, Konstantina Vryza, Glykeria Vlachogianni, Miltiades Kyprianou, Christina Routsi and Evangelos J. Giamarellos-Bourboulis

    Citation: BMC Infectious Diseases 2019 19:831

    Content type: Research article

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  39. Many gaps in the burden of resistant pathogens exist in endemic areas of low- and middle-income economies, especially those endemic for carbapenem resistance. The aim of this study is to evaluate risk factors ...

    Authors: Astrid V. Cienfuegos-Gallet, Ana M. Ocampo de Los Ríos, Patricia Sierra Viana, Faiver Ramirez Brinez, Carlos Restrepo Castro, Gustavo Roncancio Villamil, Helena del Corral Londoño and J. Natalia Jiménez

    Citation: BMC Infectious Diseases 2019 19:830

    Content type: Research article

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  40. To reduce acquisition and relapse of bacterial vaginosis (BV), lactobacilli must be maintained in the vaginal microbiome. Probiotic lactobacilli may aid this purpose. We investigated whether vaginal probiotics...

    Authors: Harold Marcotte, Per Göran Larsson, Kasper Krogh Andersen, Fanglei Zuo, Lasse Sommer Mikkelsen, Erik Brandsborg, Glenda Gray, Fatima Laher and Kennedy Otwombe

    Citation: BMC Infectious Diseases 2019 19:824

    Content type: Research article

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  41. The purpose of this study was to gather temporal trends on bacteria epidemiology and resistance of intraoperative bone culture from chronic ostemyelitis at an affiliated hospital in South China.

    Authors: Xianghong Zhang, Qiong Lu, Tang Liu, Zhihong Li and Weiliang Cai

    Citation: BMC Infectious Diseases 2019 19:823

    Content type: Research article

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  42. Cellulosimicrobium species, formely known as Oerskovia species, are gram-positive bacilli belonging to the order Actinomycetales. They rarely cause human infections. The genus comprises two pathogenic species in ...

    Authors: María Rivero, Javier Alonso, María Fernanda Ramón, Nancy Gonzales, Ana Pozo, Itxaso Marín, Ana Navascués and Regina Juanbeltz

    Citation: BMC Infectious Diseases 2019 19:816

    Content type: Case report

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  43. Invasive group B Streptococcus (GBS) disease in Chinese infants has gradually gained attention in recent years, but the molecular epidemiology of the pathogen is still not well known.

    Authors: Juan Li, Wenjing Ji, Kankan Gao, Haijian Zhou, Lihua Zhang, Xiaoping Mu, Chunlei Yuan, Xiaoshan Guan, Qiulian Deng, Lian Zhang, Huamin Zhong, Xiurong Gao, Fei Gao, Yan Long, Chien-Yi Chang, David J. McIver…

    Citation: BMC Infectious Diseases 2019 19:812

    Content type: Research article

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  44. Globally, diarrhea is the leading cause of morbidity and mortality among less than 5 years old children and it contributes to the deaths of approximately one million children every year. In Ethiopia, diarrhea ...

    Authors: Getachew Yismaw Workie, Temesgen Yihunie Akalu and Adhanom Gebreegziabher Baraki

    Citation: BMC Infectious Diseases 2019 19:804

    Content type: Research article

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  45. In Nepal, cases of Cholera occur annually either as sporadic or as outbreaks claiming the lives of many in rural areas. The present study is a laboratory based surveillance which aims to analyze the changing e...

    Authors: Nisha Rijal, Jyoti Acharya, Shailaja Adhikari, Bishnu Psd Upadhaya, Geeta Shakya, Palpasa Kansakar and Piyush Rajbhandari

    Citation: BMC Infectious Diseases 2019 19:801

    Content type: Research article

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  46. The number of new rickettsial species are rapidly increasing, and increasing numbers of Rickettsia raoultii (R. raoultii) infection cases have been detected in humans. However, neurological abnormalities caused b...

    Authors: Zhihui Dong, Yicheng Yang, Qian Wang, Songsong Xie, Shanshan Zhao, Wenbo Tan, Wumei Yuan and Yuanzhi Wang

    Citation: BMC Infectious Diseases 2019 19:796

    Content type: Case report

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