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Bacterial and fungal diseases

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of bacterial and fungal diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section includes studies relating to antibiotic resistance and healthcare-associated infections.

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  1. Although C-reactive protein (CRP) and procalcitonin (PCT) are widely used inflammatory markers for infectious diseases, their role and potential application for rickettsioses were rarely studied.

    Authors: I-Fan Lin, Jiun-Nong Lin, Chia-Ta Tsai, Yu-Ying Wu, Yen-Hsu Chen and Chung-Hsu Lai

    Citation: BMC Infectious Diseases 2020 20:334

    Content type: Research article

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  2. Brain abscess due to the Nocardia genus is rare and usually found in immunocompromised patients. The most common subtype implicated is Nocardia farcinica while brain abscess due to Nocardia brasiliensis is compar...

    Authors: Jian-Wei Zhu, Hui Zhou, Wei-Qiang Jia, Jian You and Ru-Xiang Xu

    Citation: BMC Infectious Diseases 2020 20:328

    Content type: Case report

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  3. Tularemia, a re-emerging, potential life threatening infectious disease, can present itself with nonspecific clinical symptoms including fever, chills and malaise. Taking a detailed history of exposure and a h...

    Authors: Lukas Antonitsch, Gerhard Weidinger, Gerold Stanek and Mateusz Markowicz

    Citation: BMC Infectious Diseases 2020 20:327

    Content type: Case report

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  4. While there is increasing knowledge about the gut microbiome, the factors influencing and the significance of the gut resistome are still not well understood. Infant gut commensals risk transferring multidrug-...

    Authors: Evelyn Xiu Ling Loo, Amanda Zain, Gaik Chin Yap, Rikky W. Purbojati, Daniela I. Drautz-Moses, Yan Qing Koh, Yap Seng Chong, Kok Hian Tan, Peter D. Gluckman, Fabian Yap, Johan Gunnar Eriksson, Elizabeth Tham, Lynette Pei-chi Shek, Staffan Kjelleberg, Stephan C. Schuster, Ritu Banerjee…

    Citation: BMC Infectious Diseases 2020 20:312

    Content type: Research article

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  5. Investigating distinct individual- and household-level risk factors for acquiring Helicobacter pylori (H. pylori) infection can inform disease prevention efforts and implicate possible routes of transmission. Thi...

    Authors: Kayla Schacher, Hannah Spotts, Caroline Correia, Sosina Walelign, Mehret Tesfaye, Kassu Desta, Aster Tsegaye and Bineyam Taye

    Citation: BMC Infectious Diseases 2020 20:310

    Content type: Research article

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  6. Diphtheria outbreaks occurred in endemic areas and imported and indigenous cases are reported in UE/EEA. Because of the high infectiveness and severity of the disease, early and accurate diagnosis of each susp...

    Authors: Aleksandra A. Zasada, Aldona Wiatrzyk, Urszula Czajka, Klaudia Brodzik, Kamila Formińska, Ewa Mosiej, Marta Prygiel, Katarzyna Krysztopa-Grzybowska and Karol Wdowiak

    Citation: BMC Infectious Diseases 2020 20:308

    Content type: Research article

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  7. It is commonly recommended that microbiological assessment should accompany the use of antibiotics prone to resistance. We sought to estimate the rate of microbiology testing and compare this to dispensing of ...

    Authors: Zhuoxin Peng, Andrew Hayen, Martyn D. Kirk, Sallie Pearson, Allen C. Cheng and Bette Liu

    Citation: BMC Infectious Diseases 2020 20:306

    Content type: Research article

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  8. Cerebrospinal fluid (CSF) analyses are recommended in patients with meningitis and/or encephalitis, but evidence regarding its diagnostic yield is low. We aimed to determine predictors of infectious pathogens ...

    Authors: Tolga Dittrich, Stephan Marsch, Adrian Egli, Stephan Rüegg, Gian Marco De Marchis, Sarah Tschudin-Sutter and Raoul Sutter

    Citation: BMC Infectious Diseases 2020 20:304

    Content type: Research article

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  9. Estimates of Group B Streptococcus (GBS) disease burden, antimicrobial susceptibility, and serotypes in pregnant women are limited for many resource-limited countries including Kenya. These data are required to i...

    Authors: Salano Clayton Jisuvei, Alfred Osoti and Maina Anne Njeri

    Citation: BMC Infectious Diseases 2020 20:302

    Content type: Research article

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  10. The prevalence of infections due to carbapenem-resistant Acinetobacter baumannii (CRAB) is on the rise worldwide. Polymyxins are considered as last-resort drugs for CRAB infections, but there is still controversy...

    Authors: Cheng Lyu, Yuyi Zhang, Xiaofen Liu, Jufang Wu and Jing Zhang

    Citation: BMC Infectious Diseases 2020 20:296

    Content type: Research article

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  11. Studies on bacterial meningitis in diabetics patients versus non-diabetics are scarce. In patients with diabetes, bacterial meningitis may have a different presentation, etiology and course. We analyzed and co...

    Authors: Virginia Pomar, Natividad de Benito, Albert Mauri, Pere Coll, Mercè Gurguí and Pere Domingo

    Citation: BMC Infectious Diseases 2020 20:292

    Content type: Research article

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  12. Bacterial meningitis remains a major threat for the population of the meningitis belt. Between 2004 and 2009, in the countries of this belt, more than 200,000 people were infected with a 10% mortality rate. Ho...

    Authors: Serge Mazamay, Didier Bompangue, Jean-François Guégan, Jean-Jacques Muyembe, Francis Raoul and Hélène Broutin

    Citation: BMC Infectious Diseases 2020 20:291

    Content type: Research article

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  13. The diagnosis of human anaplasmosis remains elusive and is probably often missed. This case report highlights the efficacy of molecular diagnostic techniques.

    Authors: Wolfgang Hoepler, Mateusz Markowicz, Anna-Margarita Schoetta, Alexander Zoufaly, Gerold Stanek and Christoph Wenisch

    Citation: BMC Infectious Diseases 2020 20:288

    Content type: Case report

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  14. Accurate identification Candida is important for successful therapy and epidemiology study. The aim of research is to study API 20C yeast identification system identification rate by using molecular identifica...

    Authors: Yu Shi, Yuxia Zhu, Shangrong Fan, Xiaoping Liu, Yiheng Liang and Yingying Shan

    Citation: BMC Infectious Diseases 2020 20:287

    Content type: Research article

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  15. Henoch-Schönlein purpura (HSP) may be caused by several allergens. However, to date, HSP caused by Orientia tsutsugamushi has not been reported. Here, we report an unusual rash with features of HSP caused by Orie...

    Authors: Jae Hyoung Im, Suk Jin Choi, Moon-Hyun Chung, Seung Yun Lee, Young Kyoung Park, Hea Yoon Kwon, Ji Hyeon Baek and Jin-Soo Lee

    Citation: BMC Infectious Diseases 2020 20:286

    Content type: Case report

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  16. Primary care is likely to see the highest number of Lyme disease patients. Despite this, there is limited published data regarding Lyme disease patients accessing primary care in the UK. We aim to describe tre...

    Authors: John S. P. Tulloch, Robert M. Christley, Alan D. Radford, Jenny C. Warner, Mike B. J. Beadsworth, Nick J. Beeching and Roberto Vivancos

    Citation: BMC Infectious Diseases 2020 20:285

    Content type: Research article

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  17. The spread of Enterobacteriaceae producing both carbapenemases and Mcr, encoded by plasmid-mediated colistin resistance genes, has become a serious public health problem worldwide. This study describes three clin...

    Authors: Pegah Kananizadeh, Satoshi Oshiro, Shin Watanabe, Shu Iwata, Kyoko Kuwahara-Arai, Masahiro Shimojima, Miho Ogawa, Tatsuya Tada and Teruo Kirikae

    Citation: BMC Infectious Diseases 2020 20:282

    Content type: Research article

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  18. The 13-valent Pneumococcal Conjugate Vaccine (PCV-13) was introduced in the National Immunization Programme (NIP) schedule in Russia in March 2014. Previously, the 7-valent Pneumococcal Conjugate Vaccine (PCV-...

    Authors: V. Vorobieva S. Jensen, A-S Furberg, H-C Slotved, T. Bazhukova, B. Haldorsen, D. A. Caugant, A. Sundsfjord, P. Valentiner-Branth and G. S. Simonsen

    Citation: BMC Infectious Diseases 2020 20:279

    Content type: Research article

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  19. Understanding potential risks of multi-drug resistant (MDR) pathogens from the booming poultry sector is a crucial public health concern. Campylobacter spp. are among the most important zoonotic pathogens associa...

    Authors: Sucharit Basu Neogi, Md. Mehedul Islam, S. K. Shaheenur Islam, A. H. M. Taslima Akhter, Md. Mahmudul Hasan Sikder, Shinji Yamasaki and S. M. Lutful Kabir

    Citation: BMC Infectious Diseases 2020 20:278

    Content type: Research article

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  20. Shigellosis is one of the main diarrhea diseases in developing countries. However, the transmissibility of shigellosis remains unclear.

    Authors: Qi Chen, Jia Rui, Qingqing Hu, Ying Peng, Hao Zhang, Zeyu Zhao, Yeqing Tong, Yang Wu, Yanhua Su, Benhua Zhao, Xuhua Guan and Tianmu Chen

    Citation: BMC Infectious Diseases 2020 20:272

    Content type: Research article

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  21. Scrub typhus is an acute febrile illness, which was caused by Orientia tsutsugamushi and transmitted through the bite of chiggers. The diagnosis of scrub typhus could be missed diagnosis due to the absence of ...

    Authors: Jie Chen, Xu-dong Zheng, Qi-he Dai, Wei-li Hong, You-peng Li, Rui Chen, Bing-bing Ye, Xiao-jie Mo, Peng Cui and Zhan-wei Ruan

    Citation: BMC Infectious Diseases 2020 20:270

    Content type: Case report

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  22. The purpose of the study is to discuss the correlation between the resistance rate of gram negative bacteria to fluoroquinolones (FQ) and antibiotic consumption intensity of 145 China tertiary hospitals in 2014.

    Authors: Ping Yang, Yunbo Chen, Saiping Jiang, Ping Shen, Xiaoyang Lu and Yonghong Xiao

    Citation: BMC Infectious Diseases 2020 20:269

    Content type: Research article

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  23. Leptospirosis is a neglected zoonotic disease which is a major challenge for clinicians and public health professionals in tropical countries. The cytokine storm during the second (immune) phase is thought to ...

    Authors: Indika Senavirathna, Devarajan Rathish and Suneth Agampodi

    Citation: BMC Infectious Diseases 2020 20:268

    Content type: Research article

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  24. Q fever (Coxiella burnetii infection) has been associated with adverse perinatal outcomes. After investigating the obstetrical importance of Q fever on Reunion island and demonstrating an association between inci...

    Authors: Julien Jaubert, Laura Atiana, Sophie Larrieu, Philippe De Vos, Claudine Somon-Payet, Sylvaine Porcherat, Yoan Mboussou, Florence Naze, Sandrine Picot, Malik Boukerrou, Pierre-Yves Robillard and Patrick Gérardin

    Citation: BMC Infectious Diseases 2020 20:261

    Content type: Research article

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  25. To evaluate nasal carriage, antibiotic susceptibility and molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA), as well as the risk factors of MRSA colonization, in human immunodeficien...

    Authors: Yi-Yu Hsu, David Wu, Chien-Ching Hung, Shie-Shian Huang, Fang-Hsueh Yuan, Ming-Hsun Lee, Ching-Tai Huang, Shian-Sen Shie, Po-Yen Huang, Chien-Chang Yang, Chun-Wen Cheng, Hsieh-Shong Leu, Ting-Shu Wu and Yhu-Chering Huang

    Citation: BMC Infectious Diseases 2020 20:254

    Content type: Research article

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  26. Treatment of resistant Pseudomonas aeruginosa infection continues to be a challenge in Latin American countries (LATAM). We synthesize the literature on the use of appropriate initial antibiotic therapy (AIAT) an...

    Authors: Alfredo Ponce de Leon, Sanjay Merchant, Gowri Raman, Esther Avendano, Jeffrey Chan, Griselda Tepichin Hernandez and Eric Sarpong

    Citation: BMC Infectious Diseases 2020 20:250

    Content type: Research article

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  27. Infections with multidrug-resistant organisms (MDRO) pose a serious threat to patients with dysregulated immunity such as in hemophagocytic lymphohistiocytosis (HLH), but such infections have rarely been compr...

    Authors: Mohammad Rubayet Hasan, Manu Somasundaram Sundaram, Sathyavathi Sundararaju, Kin-Ming Tsui, Mohammed Yousuf Karim, Diane Roscoe, Omar Imam, Mohammad A. Janahi, Eva Thomas, Simon Dobson, Rusung Tan, Patrick Tang and Andres Perez Lopez

    Citation: BMC Infectious Diseases 2020 20:237

    Content type: Case report

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  28. Melioidosis-associated peri-prosthetic infection is extremely rare. To date, melioidosis associated septic arthritis of the ankle joint following a medial malleolar internal fixation has not been reported.

    Authors: Umesh Jayarajah, Arulprashanth Arulanantham, Vimaleswaran Koculen, Chamikara Palkumbura, Aadil Faleel and Rukshan Sooriyarachchi

    Citation: BMC Infectious Diseases 2020 20:236

    Content type: Case report

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  29. The most common infection in patients positive for anti-interferon-gamma autoantibodies (anti-IFN-γ AAbs) is disseminated nontuberculous mycobacterial (dNTM) infection. Here, we report a rare case of triple in...

    Authors: Pongprueth Rujirachun, Jirath Sangwongwanich and Methee Chayakulkeeree

    Citation: BMC Infectious Diseases 2020 20:232

    Content type: Case report

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  30. The spectrum of yeasts and their antifungal susceptibility profile are poorly known and treatment of fungal disease has remained empirical. The aim of this study is to determine the spectrum and antifungal sus...

    Authors: Elias Seyoum, Adane Bitew and Amete Mihret

    Citation: BMC Infectious Diseases 2020 20:231

    Content type: Research article

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  31. Vancomycin-resistant enterococcus (VRE) is an important cause of infection in immunocompromised populations. Few studies have described the characteristics of vanB VRE infection. We sought to describe the epidemi...

    Authors: Ouli Xie, Monica A. Slavin, Benjamin W. Teh, Ashish Bajel, Abby P. Douglas and Leon J. Worth

    Citation: BMC Infectious Diseases 2020 20:228

    Content type: Research article

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  32. Rapid control of cholera outbreaks is a significant challenge in overpopulated urban areas. During late-2017, Kinshasa, the capital of the Democratic Republic of the Congo, experienced a cholera outbreak that ...

    Authors: Didier Bompangue, Sandra Moore, Nadège Taty, Benido Impouma, Bertrand Sudre, Richard Manda, Thierno Balde, Franck Mboussou and Thierry Vandevelde

    Citation: BMC Infectious Diseases 2020 20:226

    Content type: Research article

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  33. Otitis media is inflammation of the middle ear, comprising a spectrum of diseases. It is the commonest episode of infection in children, which often occurs after an acute upper respiratory tract infection. Oti...

    Authors: Tewodros Tesfa, Habtamu Mitiku, Mekonnen Sisay, Fitsum Weldegebreal, Zerihun Ataro, Birhanu Motbaynor, Dadi Marami and Zelalem Teklemariam

    Citation: BMC Infectious Diseases 2020 20:225

    Content type: Research article

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  34. Streptococcus suis is a zoonotic pathogen that causes serious systemic infections in pigs and occupation-related infections in humans who contact with pigs or pork products. In China, it has caused two outbreaks ...

    Authors: Fei Jiang, Jingjing Guo, Chen Cheng and Bing Gu

    Citation: BMC Infectious Diseases 2020 20:223

    Content type: Case report

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  35. This study represents the first Scottish retrospective analysis of the microbiology of diabetic foot infections (DFIs). The aims were to compare the microbiological profile of DFIs treated at a Scottish tertia...

    Authors: Katherine E. Macdonald, Crispin Y. Jordan, Emma Crichton, Judith E. Barnes, Gillian E. Harkin, Lesley M. L. Hall and Joshua D. Jones

    Citation: BMC Infectious Diseases 2020 20:218

    Content type: Research article

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  36. Tick-borne lymphadenopathy (TIBOLA) is an infectious disease, mainly caused by species from the spotted fever group rickettsiae and is characterized by enlarged lymph nodes following a tick bite. Among cases o...

    Authors: Jun-Won Seo, Choon-Mee Kim, Na Ra Yun, Dong-Min Kim, Sung Soon Kim, Sangho Choi and Hyuk Chu

    Citation: BMC Infectious Diseases 2020 20:216

    Content type: Case report

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  37. Pulmonary endarteritis is a rare clinical phenomenon with congenital heart that can potentially lead to major complications.

    Authors: Arezoo Khosravi, Zohreh Rostami, Mohammad Javanbakht, Nematollah Jonaidi Jafari, Mohsen Sadeghi Ghahroudi, Mohammad Hassan Kalantar-Motamed, Ramezan Jafari and Behzad Einollahi

    Citation: BMC Infectious Diseases 2020 20:212

    Content type: Case report

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  38. Cellulitis, a frequent cause of admission of adult patients to medical wards, occasionally evolves to sepsis. In this study we analyze the factors related to sepsis development.

    Authors: J. Collazos, B. de la Fuente, J. de la Fuente, A. García, H. Gómez, C. Menéndez, H. Enríquez, P. Sánchez, M. Alonso, I. López-Cruz, M. Martín-Regidor, A. Martínez-Alonso, J. Guerra, A. Artero, M. Blanes and V. Asensi

    Citation: BMC Infectious Diseases 2020 20:211

    Content type: Research article

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  39. Campylobacter jejuni is a motile, gram-negative rod known for causing self-limiting enterocolitis while rarely causing extraintestinal infections. We report the first case of a patient with Campylobacter jejuni o...

    Authors: Joost Hartman, Matthijs Westerman and Jiri F. P. Wagenaar

    Citation: BMC Infectious Diseases 2020 20:199

    Content type: Case report

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  40. Microbial infection is the main cause of increased morbidity and mortality in burn patients, especially infections caused by multiple drug-resistant organisms (MDRO). The purpose of this study was to explore m...

    Authors: Yin-Yin Chen, Ping-Feng Wu, Chii-Shya Chen, Ian-Horng Chen, Wan-Tsuei Huang and Fu-Der Wang

    Citation: BMC Infectious Diseases 2020 20:193

    Content type: Research article

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  41. Human psittacosis, caused by Chlamydia (C.) psittaci, is likely underdiagnosed and underreported, since tests for C. psittaci are often not included in routine microbiological diagnostics. Source tracing traditio...

    Authors: Lenny Hogerwerf, Inge Roof, Marianne J. K. de Jong, Frederika Dijkstra and Wim van der Hoek

    Citation: BMC Infectious Diseases 2020 20:192

    Content type: Research article

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  42. The presentation of clinical leptospirosis has been historically associated with animal workers, slaughterhouse workers and medical veterinarians. This association has shifted to be related to flooding events ...

    Authors: J. García-Méndez, E. Cervera-Ceballos, D. Atilano-López, S. Arroyo-Escalante, D. Moncada-Barrón, M. Leyva-Leyva, R. Hernández-Castro and E. M. Carrillo-Casas

    Citation: BMC Infectious Diseases 2020 20:186

    Content type: Case report

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  43. Staphylococcus aureus (S. aureus) arthritis is one of the most detrimental joint diseases known and leads to severe joint destruction within days. We hypothesized that the provision of auxiliary immunoregulation ...

    Authors: Berglind Bergmann, Ying Fei, Pernilla Jirholt, Zhicheng Hu, Maria Bergquist, Abukar Ali, Catharina Lindholm, Olov Ekwall, Guillaume Churlaud, David Klatzmann, Tao Jin and Inger Gjertsson

    Citation: BMC Infectious Diseases 2020 20:185

    Content type: Research article

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  44. The burden of leptospirosis in Indonesia is poorly understood. Data from an observational study conducted from 2013 to 2016 in seven cities across Indonesia was used to estimate the incidence of leptospirosis ...

    Authors: Muhammad Hussein Gasem, Usman Hadi, Bachti Alisjahbana, Emiliana Tjitra, M. M. D. E. A. H. Hapsari, Endang Sri Lestari, Abu Tholib Aman, Dewi Lokida, Gustiani Salim, Herman Kosasih, Ketut Tuti Parwati Merati, Kanti Laras, Mansyur Arif, Nurhayati Lukman, Pratiwi Sudarmono, Vivi Lisdawati…

    Citation: BMC Infectious Diseases 2020 20:179

    Content type: Research article

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