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Bacterial and fungal diseases

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of bacterial and fungal diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section includes studies relating to antibiotic resistance and healthcare-associated infections.

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  1. Lactobacillus jensenii, L. iners, L. crispatus and L. gasseri are the most frequently occurring lactobacilli in the vagina. However, the native species vary widely according to the studied population. The presen...

    Authors: Marcos Daniel Martínez-Peña, Graciela Castro-Escarpulli and Ma Guadalupe Aguilera-Arreola

    Citation: BMC Infectious Diseases 2013 13:189

    Content type: Research article

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  2. Extended-spectrum beta-lactamase–producing Enterobacteriaceae (ESBL-E) are a growing concern in hospitals and the community. How to control the nosocomial ESBL-E transmission is a matter of debate. Contact iso...

    Authors: Matthieu Domenech de Cellès, Jean-Ralph Zahar, Véronique Abadie and Didier Guillemot

    Citation: BMC Infectious Diseases 2013 13:187

    Content type: Research article

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  3. The present study was designed to investigate whether teicoplanin minimum inhibitory concentrations (MICs) of methicillin-resistant Staphylococcus aureus (MRSA) isolates play a role in the prognosis of patient wi...

    Authors: Jann-Tay Wang, Hau-Shin Wu, Chia-Min Weng, Le-Yin Hsu and Fu-Der Wang

    Citation: BMC Infectious Diseases 2013 13:182

    Content type: Research article

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  4. Day-care centre (DCC) attendees play a central role in maintaining the circulation of Streptococcus pneumoniae (pneumococcus) in the population. The prevalence of pneumococcal carriage is highest in DCC attendees...

    Authors: Delphine Pessoa, Fabian Hoti, Ritva Syrjänen, Raquel Sá-Leão, Tarja Kaijalainen, M Gabriela M Gomes and Kari Auranen

    Citation: BMC Infectious Diseases 2013 13:180

    Content type: Research article

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  5. Unnecessary long-term use of broad-spectrum antibiotics is linked to the emergence and selection of resistant bacteria, prolonged hospitalisation and increased costs. Several clinical trials indicate that the ...

    Authors: Evelien Assink-de Jong, Dylan W de Lange, Jos A van Oers, Maarten W Nijsten, Jos W Twisk and Albertus Beishuizen

    Citation: BMC Infectious Diseases 2013 13:178

    Content type: Study protocol

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  6. This study aimed to assess the costs and clinical benefits of the 13-valent pneumococcal conjugate vaccine (PCV13) administered annually to the 65-year-old cohort in Spain versus the alternative of not vaccina...

    Authors: Roberto Pradas, Angel Gil de Miguel, Alejandro Álvaro, Ruth Gil-Prieto, Reyes Lorente, Cristina Méndez, Pablo Guijarro and Fernando Antoñanzas

    Citation: BMC Infectious Diseases 2013 13:175

    Content type: Research article

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  7. Diagnosis of community-acquired pneumonia (CAP) caused by Mycoplasma pneumoniae in adults and adolescents is hampered by a lack of rapid and standardized tests for detection.

    Authors: Jiuxin Qu, Li Gu, Jiang Wu, Jianping Dong, Zenghui Pu, Yan Gao, Ming Hu, Yongxiang Zhang, Feng Gao, Bin Cao and Chen Wang

    Citation: BMC Infectious Diseases 2013 13:172

    Content type: Research article

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  8. Epidemiologic studies of skin and soft tissue infections (SSTIs) depend upon accurate case identification. Our objective was to evaluate the positive predictive value (PPV) of electronic medical record data fo...

    Authors: Pamela J Levine, Miriam R Elman, Ravina Kullar, John M Townes, David T Bearden, Rowena Vilches-Tran, Ian McClellan and Jessina C McGregor

    Citation: BMC Infectious Diseases 2013 13:171

    Content type: Research article

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  9. In 1872, in British Medical Journal (BMJ) Dr. David Ferrier published that Sarcina ventriculi (Goodsir) constantly occurred in the blood of man and the lower animals. His observation was based on bleeding experim...

    Authors: Tamara Tuuminen, Päivi Suomala and Sakari Vuorinen

    Citation: BMC Infectious Diseases 2013 13:169

    Content type: Case report

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  10. Prevalence of bacteremia caused by non-fermentative gram-negative bacteria (NFGNB) has been increasing over the past decade. Although many studies have already investigated epidemiology of NFGNB bacteremia, mo...

    Authors: Pinyo Rattanaumpawan, Prapassorn Ussavasodhi, Pattarachai Kiratisin and Nalinee Aswapokee

    Citation: BMC Infectious Diseases 2013 13:167

    Content type: Research article

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  11. Early identification of pathogens and antimicrobial resistance in bloodstream infections (BSIs) decreases morbidity and mortality, particularly in immunocompromised patients. The aim of the present study was t...

    Authors: Liana Carballo Menezes, Talita Trevizani Rocchetti, Karen de Castro Bauab, Paola Cappellano, Milene Gonçalves Quiles, Fabianne Carlesse, Jose Salvador Rodrigues de Oliveira and Antonio Carlos Campos Pignatari

    Citation: BMC Infectious Diseases 2013 13:166

    Content type: Research article

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  12. Burkholderia pseudomallei, the causative agent of melioidosis, is endemic to Southeast Asia and northern Australia. Clinical manifestations of disease are diverse, ranging from chronic infection to acute septica...

    Authors: Yuka Hara, Chui-Yoke Chin, Rahmah Mohamed, Savithri D Puthucheary and Sheila Nathan

    Citation: BMC Infectious Diseases 2013 13:165

    Content type: Research article

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  13. In 2003, nosocomial infections caused by vancomycin-resistant enterococci (VRE) occurred rarely in Taiwan. Between 2003 and 2010, however, the average prevalence of vancomycin resistance among enterococci spp....

    Authors: Sai-Cheong Lee, Mi-Si Wu, Hsiang-Ju Shih, Shu-Huan Huang, Meng-Jiun Chiou, Lai-Chu See and Liang-Kee Siu

    Citation: BMC Infectious Diseases 2013 13:163

    Content type: Research article

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  14. In recent years, Nocardia farcinica has been reported to be an increasingly frequent cause of localized and disseminated infections in the immunocompromised patient. However, recent literature is limited. We repo...

    Authors: Pasquale De Nardo, Maria Letizia Giancola, Salvatore Noto, Elisa Gentilotti, Piero Ghirga, Chiara Tommasi, Rita Bellagamba, Maria Grazia Paglia, Emanuele Nicastri, Andrea Antinori and Angela Corpolongo

    Citation: BMC Infectious Diseases 2013 13:162

    Content type: Case report

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  15. Cefepime is a fourth generation cephalosporin antimicrobial. Its extended antimicrobial activity and infrequent tendency to engender resistance make it popular for the treatment of infections. However, proper ...

    Authors: Shi Qingping, Ding Feng, Sang Ran, Liu Yan, Yuan HaoYu and Yu Meiling

    Citation: BMC Infectious Diseases 2013 13:160

    Content type: Research article

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  16. Nosocomial infection diagnosis in the intensive care unit (ICU) remains a challenge. We compared routine measurements of procalcitonin (PCT), C-reactive protein (CRP), white blood cell count (WBC) and temperat...

    Authors: Laurent Robriquet, Caroline Séjourné, Eric Kipnis, Michele D’herbomez and François Fourrier

    Citation: BMC Infectious Diseases 2013 13:159

    Content type: Research article

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  17. Procalcitonin (PCT)-protocols to guide antibiotic treatment in severe infections are known to be effective. But less is known about the long-term effects of such protocols on antibiotic consumption under real ...

    Authors: Andreas Hohn, Stefan Schroeder, Anna Gehrt, Kathrin Bernhardt, Berthold Bein, Karl Wegscheider and Marcel Hochreiter

    Citation: BMC Infectious Diseases 2013 13:158

    Content type: Research article

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  18. Q fever is a zoonosis that is present in many countries. Q fever fatigue syndrome (QFS) is one of the most frequent sequelae after an acute Q fever infection. QFS is characterized by persistent fatigue followi...

    Authors: Stephan P Keijmel, Corine E Delsing, Tom Sprong, Gijs Bleijenberg, Jos WM van der Meer, Hans Knoop and Chantal P Bleeker-Rovers

    Citation: BMC Infectious Diseases 2013 13:157

    Content type: Study protocol

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  19. Enterococci normally inhabit the intestinal tract of humans and are also a potential pathogen in causing nosocomial infections. The increase in antibiotic resistance and transfer of antibiotic resistance gene to

    Authors: Muhammad Arfat Yameen, Saira Iram, Abdul Mannan, Shujaat Ali Khan and Naeem Akhtar

    Citation: BMC Infectious Diseases 2013 13:156

    Content type: Research article

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  20. Abscesses involving the inguinal region as manifestations of complex soft-tissue infections are rare, and the infectious route is usually unclear. The purpose of this study was to ascertain the importance of i...

    Authors: Wei-Hsiu Hsu, Ching-Yu Lee, Li-Ju Lai, Tsung-Yu Huang and Kuo-Ti Peng

    Citation: BMC Infectious Diseases 2013 13:155

    Content type: Research article

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  21. Invasive listeriosis is a rare, life-threatening foodborne disease. Lombardy, an Italian region accounting for 16% of the total population, reported 55% of all listeriosis cases in the years 2006-2010. The aim...

    Authors: Caterina Mammina, Antonio Parisi, Anna Guaita, Aurora Aleo, Celestino Bonura, Antonino Nastasi and Mirella Pontello

    Citation: BMC Infectious Diseases 2013 13:152

    Content type: Research article

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    The Erratum to this article has been published in BMC Infectious Diseases 2015 15:202

  22. Aggregate comorbidity scores are useful for summarizing risk and confounder control in studies of hospital-associated infections. The Chronic Disease Score – Infectious Diseases (CDS-ID) was developed for this...

    Authors: Vanessa Stevens, Cathleen Concannon, Edwin van Wijngaarden and Jessina McGregor

    Citation: BMC Infectious Diseases 2013 13:150

    Content type: Research article

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  23. Poststreptococcal syndrome (PSS) can be a consequence of nonpurulent primary infection with group A streptococci (GAS). Postreptococcal uveitis is a well recognized entity with quite a few descriptions in the ...

    Authors: Iwona Rospond-Kubiak, Agata Brązert, Jarosław Kocięcki and Jan Bręborowicz

    Citation: BMC Infectious Diseases 2013 13:149

    Content type: Case report

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  24. Clostridium difficile infection (CDI) continues to be a frequent and potentially severe infection. There is currently no validated clinical tool for use at the time of CDI diagnosis to categorize patients in o...

    Authors: Mark A Miller, Thomas Louie, Kathleen Mullane, Karl Weiss, Arnold Lentnek, Yoav Golan, Yin Kean and Pam Sears

    Citation: BMC Infectious Diseases 2013 13:148

    Content type: Research article

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  25. Candidemia is a severe fungal infection that primarily affects hospitalized and/or immunocompromised patients. Mononuclear phagocytes have been recognized as pivotal immune cells which act in the recognition o...

    Authors: Thais Fernanda de Campos Fraga-Silva, James Venturini and Maria Sueli Parreira de Arruda

    Citation: BMC Infectious Diseases 2013 13:147

    Content type: Research article

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  26. In developed countries, Clostridium difficile infection (CDI) represents an emerging threat in terms of morbidity and mortality rates. In our country limited CDI epidemiological data can be found.

    Authors: Stefano Di Bella, Maria Musso, Maria A Cataldo, Marcello Meledandri, Eugenio Bordi, Daniela Capozzi, Maria C Cava, Patrizia Chiaradonna, Grazia Prignano and Nicola Petrosillo

    Citation: BMC Infectious Diseases 2013 13:146

    Content type: Research article

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  27. Brucellosis is a common zoonosis that can cause a severe febrile illness in humans. It constitutes a persistent health problem in many developing countries around the world. It is one of the most frequently re...

    Authors: Ibrahim Hassan Kamal, Basim Al Gashgari, Said Salama Moselhy, Taha Abdullah Kumosani and Khalid Omar Abulnaja

    Citation: BMC Infectious Diseases 2013 13:145

    Content type: Research article

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  28. Histoplasmosis is a common opportunistic fungal infection that is observed almost exclusively in immunodeficient patients, especially those with AIDS. Immunocompetent individuals that suffer from histoplasmosi...

    Authors: Biwei Yang, Lixia Lu, Dajiang Li, Li Liu, Libin Huang, Liyu Chen, Hong Tang and Lichun Wang

    Citation: BMC Infectious Diseases 2013 13:143

    Content type: Case report

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  29. Acinetobacter baumannii hospital-acquired pneumonia (HAP) is associated with a high mortality worldwide. Non-ventilated patients with HAP (NVHAP) caused by nosocomial pathogens are reported to have a more favora...

    Authors: Ya-Sung Yang, Yi-Tzu Lee, Tsai-Wang Huang, Jun-Ren Sun, Shu-Chen Kuo, Chin-Hsuan Yang, Te-Li Chen, Jung-Chung Lin, Chang-Phone Fung and Feng-Yee Chang

    Citation: BMC Infectious Diseases 2013 13:142

    Content type: Research article

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  30. Lower limb cellulitis and deep vein thrombosis share clinical features and investigation of patients with cellulitis for concurrent DVT is common. The prevalence of DVT in this group is uncertain. This study a...

    Authors: Michael J Maze, Sean Skea, Alan Pithie, Sarah Metcalf, John F Pearson and Stephen T Chambers

    Citation: BMC Infectious Diseases 2013 13:141

    Content type: Research article

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  31. The distal esophagus harbors a complex bacterial population. We hypothesized that a better understanding of bacterial communities in the esophagus would facilitate understanding of the role of bacteria in esop...

    Authors: Ning Liu, Takafumi Ando, Kazuhiro Ishiguro, Osamu Maeda, Osamu Watanabe, Kohei Funasaka, Masanao Nakamura, Ryoji Miyahara, Naoki Ohmiya and Hidemi Goto

    Citation: BMC Infectious Diseases 2013 13:130

    Content type: Research article

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  32. Several symptoms are classically thought to be suggestive of pertussis in children, but the diagnostic value of these symptoms in adolescent and adult patients is unclear. We evaluated the accuracy of the clin...

    Authors: Naoyuki Miyashita, Hiroto Akaike, Hideto Teranishi, Yasuhiro Kawai, Kazunobu Ouchi, Tadashi Kato, Toshikiyo Hayashi and Niro Okimoto

    Citation: BMC Infectious Diseases 2013 13:129

    Content type: Research article

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  33. Within the genus Aspergillus, A. flavus is the second most important species of clinical significance. It is predominantly associated with infections involving sinuses, eye and skin, mostly in geographic regions ...

    Authors: Faten Al-Wathiqi, Suhail Ahmad and Ziauddin Khan

    Citation: BMC Infectious Diseases 2013 13:126

    Content type: Research article

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  34. Long Term Care Facilities (LTCFs) play a key role in guaranteeing care to patients in developed countries. Many patients, mostly elderly, access LTCFs at some time in their lives, and their healthcare pathways...

    Authors: Luca Arnoldo, Roberta Migliavacca, Laura Regattin, Annibale Raglio, Laura Pagani, Elisabetta Nucleo, Melissa Spalla, Francesca Vailati, Antonella Agodi, Adriana Mosca, Carla Zotti, Stefano Tardivo, Ines Bianco, Adele Rulli, Paola Gualdi, Pietro Panetta…

    Citation: BMC Infectious Diseases 2013 13:124

    Content type: Research article

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  35. Ventilator-associated pneumonia (VAP) is considered the most common nosocomial infection in the intensive care unit (ICU), but its features are not fully known in many hospitals in Brazil. We identified clinic...

    Authors: Marília M Resende, Sílvio G Monteiro, Bianca Callegari, Patrícia M S Figueiredo, Cinara R A V Monteiro and Valério Monteiro-Neto

    Citation: BMC Infectious Diseases 2013 13:119

    Content type: Research article

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  36. Published models predicting nasal colonization with Methicillin-resistant Staphylococcus aureus among hospital admissions predominantly focus on separation of carriers from non-carriers and are frequently evaluat...

    Authors: Johannes Elias, Peter U Heuschmann, Corinna Schmitt, Frithjof Eckhardt, Hartmut Boehm, Sebastian Maier, Annette Kolb-Mäurer, Hubertus Riedmiller, Wolfgang Müllges, Christoph Weisser, Christian Wunder, Matthias Frosch and Ulrich Vogel

    Citation: BMC Infectious Diseases 2013 13:111

    Content type: Research article

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  37. We conducted a prospective, observational study in Barcelona to determine the epidemiology, clinical features, and outcome of elderly patients with acute bacterial meningitis (ABM) compared with younger adults.

    Authors: Pere Domingo, Virginia Pomar, Natividad de Benito and Pere Coll

    Citation: BMC Infectious Diseases 2013 13:108

    Content type: Research article

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  38. The clinical significance of bacteraemia secondary to non-typhoidal Salmonella (NTS) gastroenteritis in hospitalised adults is uncertain.

    Authors: Christopher M Parry, Sherine Thomas, Esther J Aspinall, Richard PD Cooke, Stephen J Rogerson, Anthony D Harries and Nicholas J Beeching

    Citation: BMC Infectious Diseases 2013 13:107

    Content type: Research article

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  39. Voriconazole is approved for treatment of invasive aspergillosis and other invasive fungal infections, but the role for therapeutic drug monitoring (TDM) is not clear.

    Authors: Helen Y Chu, Rupali Jain, Hu Xie, Paul Pottinger and David N Fredricks

    Citation: BMC Infectious Diseases 2013 13:105

    Content type: Research article

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  40. Few data exist on viral and bacterial etiology of acute lower respiratory infections (ALRI) in ≥5 year –old persons in the tropics.

    Authors: Sirenda Vong, Bertrand Guillard, Laurence Borand, Blandine Rammaert, Sophie Goyet, Vantha Te, Patrich Lorn Try, Sopheak Hem, Sareth Rith, Sowath Ly, Philippe Cavailler, Charles Mayaud and Philippe Buchy

    Citation: BMC Infectious Diseases 2013 13:97

    Content type: Research article

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  41. Community Acquired Pneumonia (CAP) is a commonly encountered disease, one third of which is Severe Community Acquired Pneumonia (SCAP) that can be potentially fatal. There is a paucity of data on etiology and ...

    Authors: Ali Khawaja, Ali Bin Sarwar Zubairi, Fahad Khan Durrani and Afia Zafar

    Citation: BMC Infectious Diseases 2013 13:94

    Content type: Research article

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  42. Deep eosinophilic granulomatous abscesses, as distinguished from eosinophilic subcutaneous abscesses, are rare. Most reports are from the Far-East and India where the most commonly attributed cause is Toxocara. S...

    Authors: Hemmin A Hassan, Runnak A Majid, Nawshirwan G Rashid, Bryar E Nuradeen, Qalandar H Abdulkarim, Tahir A Hawramy, Rekawt M Rashid, Alton B Farris, Jeannette Guarner and Michael D Hughson

    Citation: BMC Infectious Diseases 2013 13:91

    Content type: Research article

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  43. Bloodstream infections in neonates and infants are life-threatening emergencies. Identification of the common bacteria causing such infections and their susceptibility patterns will provide necessary informati...

    Authors: Samuel EK Acquah, Lawrence Quaye, Kenneth Sagoe, Juventus B Ziem, Patricia I Bromberger and Anthony A Amponsem

    Citation: BMC Infectious Diseases 2013 13:89

    Content type: Research article

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  44. Q fever caused by Coxiella burnetii is transmitted to humans by inhalation of aerosols from animal birth products. Q fever in pregnancy is suspected to be a potential cause of fetal and maternal morbidity and fet...

    Authors: Stine Yde Nielsen, Anne-Marie Nybo Andersen, Kåre Mølbak, Niels Henrik Hjøllund, Bjørn Kantsø, Karen Angeliki Krogfelt and Tine Brink Henriksen

    Citation: BMC Infectious Diseases 2013 13:87

    Content type: Research article

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  45. Burkholderia mallei and B. pseudomallei are two closely related species of highly virulent bacteria that can be difficult to detect. Pathogenic Burkholderia are endemic in many regions worldwide and cases of inf...

    Authors: Ingmar Janse, Raditijo A Hamidjaja, Amber CA Hendriks and Bart J van Rotterdam

    Citation: BMC Infectious Diseases 2013 13:86

    Content type: Research article

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  46. Hospitalizations with community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection have increased in New York City, with substantial geographic variation across neighborhoods. While indivi...

    Authors: Amanda M Farr, Melissa A Marx, Don Weiss and Denis Nash

    Citation: BMC Infectious Diseases 2013 13:84

    Content type: Research article

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  47. The chronic use of antifungal agents in the treatment of fungal infection in general and oropharyngeal candidiasis mainly in AIDS patient’s leads to the selection of strain resistant to these therapies and a s...

    Authors: Andargachew Mulu, Afework Kassu, Belay Anagaw, Beyene Moges, Aschalew Gelaw, Martha Alemayehu, Yeshambel Belyhun, Fantahun Biadglegne, Zewdu Hurissa, Feleke Moges and Emiko Isogai

    Citation: BMC Infectious Diseases 2013 13:82

    Content type: Research article

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  48. Limited data suggest that fluorine-18 fluoro-2-deoxy-D-glucose (F-18 FDG) positron emission tomography combined with computed tomography (PET/CT) scan may be useful for diagnosing infections of the spine. Bruc...

    Authors: Savvas Ioannou, Sofia Chatziioannou, Spiros G Pneumaticos, Alexandra Zormpala and Nikolaos V Sipsas

    Citation: BMC Infectious Diseases 2013 13:73

    Content type: Research article

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