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Bacterial and fungal diseases

Section edited by Ivan FN Hung, Jorge Garbino and Kelvin To

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of bacterial and fungal diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section includes studies relating to antibiotic resistance and healthcare-associated infections.

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  1. Content type: Research article

    Corynebacterium diphtheriae is a re-emerging pathogen in Europe causing invasive infections in vaccinated persons and classical diphtheria in unvaccinated persons. In the presented study we analysed genetic chang...

    Authors: Urszula Czajka, Aldona Wiatrzyk, Ewa Mosiej, Kamila Formińska and Aleksandra A. Zasada

    Citation: BMC Infectious Diseases 2018 18:121

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  2. Content type: Research article

    Various studies have identified numerous factors associated with poor clinical outcomes in patients with Staphylococcus aureus bacteraemia (SAB). A new study was created to provide deeper insight into in-hospital...

    Authors: Natasha E. Holmes, J. Owen Robinson, Sebastiaan J. van Hal, Wendy J. Munckhof, Eugene Athan, Tony M. Korman, Allen C. Cheng, John D. Turnidge, Paul D. R. Johnson and Benjamin P. Howden

    Citation: BMC Infectious Diseases 2018 18:107

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  3. Content type: Case report

    Concurrent presence of dengue hemorrhagic fever (DHF), tropical pyomyositis and septicemia due to methicillin-resistant Staphylococcus aureus (MRSA) in a previously healthy person has never been reported. These t...

    Authors: N. D. B. Ehelepola, R. K. G. M. Rajapaksha, D. M. U. B. Dhanapala, T. D. K. Thennekoon and S. Ponnamperuma

    Citation: BMC Infectious Diseases 2018 18:99

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  4. Content type: Research article

    Fluoroquinolones (FQ) are increasingly prescribed for children, despite being labeled for only a limited number of labeled pediatric indications. In this multicenter retrospective drug utilization study, we an...

    Authors: Kevin Meesters, Reiner Mauel, Evelyn Dhont, Johan Vande Walle and Pauline De Bruyne

    Citation: BMC Infectious Diseases 2018 18:89

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  5. Content type: Research article

    Colonization with Staphylococcus aureus is a well-defined risk factor for disease in hospitals, which can range from minor skin infections to severe, systemic diseases. However, the generalizability of this findi...

    Authors: Marina W. Kim, Ben K. Greenfield, Robert E. Snyder, Craig M. Steinmaus and Lee W. Riley

    Citation: BMC Infectious Diseases 2018 18:86

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  6. Content type: Research article

    Right-sided infective endocarditis (RSIE) is an uncommon diagnosis accounting for less than 10% of cases of infective endocarditis. Optimal management for severely ill patients with RSIE remains challenging be...

    Authors: Hugues Georges, Olivier Leroy, Norair Airapetian, Nicolas Lamblin, Elie Zogheib, Patrick Devos and Sebastien Preau

    Citation: BMC Infectious Diseases 2018 18:85

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  7. Content type: Research article

    Human fecal carriage of Enterobacteriaceae possessing mobilized colistin resistance genes (mcr-1 and mcr-2) remains obscure in Hong Kong. As part of routine surveillance on emerging antibiotic resistance, we cond...

    Authors: Wai-Sing Chan, Chun-Hang Au, Dona N. Ho, Tsun-Leung Chan, Edmond Shiu-Kwan Ma and Bone Siu-Fai Tang

    Citation: BMC Infectious Diseases 2018 18:81

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  8. Content type: Case report

    Melioidosis, the disease caused by Burkholderia pseudomallei is endemic in the Northeastern part of Thailand, South-East Asia, and Northern Australia. The pelvic involvement of disease is rare even in an endemic ...

    Authors: Pattaranit Nernsai, Areepan Sophonsritsuk, Srithean Lertvikool, Artit Jinawath and Maria Nina Chitasombat

    Citation: BMC Infectious Diseases 2018 18:73

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  9. Content type: Research article

    People with diabetes may be at higher risk for acquiring infections through both glucose-dependent and biologic pathways independent of glycemic control. Our aim was to estimate the association between diabete...

    Authors: Waseem Abu-Ashour, Laurie K Twells, James E Valcour and John-Michael Gamble

    Citation: BMC Infectious Diseases 2018 18:67

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  10. Content type: Research article

    Diarrhea is the leading infectious cause of childhood morbidity and mortality. Among bacterial agents, diarrheagenic Escherichia coli (DEC) is the major causal agent of childhood diarrhea in developing countries,...

    Authors: Yu Zhou, Xuhui Zhu, Hongyan Hou, Yanfang Lu, Jing Yu, Lie Mao, Liyan Mao and Ziyong Sun

    Citation: BMC Infectious Diseases 2018 18:63

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  11. Content type: Case report

    In the last decades, probiotics have been widely used as food supplements because of their putative beneficial health effects. They are generally considered safe but rare reports of serious infections caused b...

    Authors: Evangelo Boumis, Alessandro Capone, Vincenzo Galati, Carolina Venditti and Nicola Petrosillo

    Citation: BMC Infectious Diseases 2018 18:65

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  12. Content type: Research article

    Studies have shown that the prognosis of the treatment of methicillin-susceptible S. aureus (MSSA) with glycopeptides is inferior compared to treatment with β-lactam. However, there are only few studies comparing...

    Authors: Dong Hyun Oh, Jung Ju Kim, Jinnam Kim, Hye Seong, Se Ju Lee, Yong Chan Kim, Eun Jin Kim, In Young Jung, Woo Yong Jeong, Su Jin Jeong, Nam Su Ku, Sang Hoon Han, Jun Yong Choi, Young Goo Song and June Myung Kim

    Citation: BMC Infectious Diseases 2018 18:60

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  13. Content type: Research article

    The aim of this study was to identify clinical risk factors for antimicrobial resistances and multidrug resistance (MDR) in urinary tract infections (UTI) in an emergency department in order to improve empiric...

    Authors: Sebastian Bischoff, Thomas Walter, Marlis Gerigk, Matthias Ebert and Roger Vogelmann

    Citation: BMC Infectious Diseases 2018 18:56

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  14. Content type: Research article

    S.aureus is a predominant pathogen that causes infection in critically ill patients, but little information exists regarding the characterization of S. aureus from different sources in burn patients in southeaste...

    Authors: Kaisen Chen, Shirong Lin, Peiqun Li, Qiuyue Song, Dong Luo, Tao Liu, Lingbing Zeng and Wei Zhang

    Citation: BMC Infectious Diseases 2018 18:51

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  15. Content type: Research article

    Non-typhoidal Salmonella (NTS) cause the majority of bloodstream infections in Ghana, however the mode of transmission and source of invasive NTS in Africa are poorly understood. This study compares NTS from wate...

    Authors: Denise Dekker, Ralf Krumkamp, Daniel Eibach, Nimako Sarpong, Kennedy Gyau Boahen, Michael Frimpong, Elina Fechtner, Sven Poppert, Ralf Matthias Hagen, Norbert Georg Schwarz, Yaw Adu-Sarkodie, Ellis Owusu-Dabo, Justin Im, Florian Marks, Hagen Frickmann and Jürgen May

    Citation: BMC Infectious Diseases 2018 18:47

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  16. Content type: Case report

    Transdiaphragmatic extension of pyogenic liver abscess is the rarest cause of pericarditis and pleural empyema. It is a rapidly progressive and highly lethal infection with mortality rates reaching 100% if lef...

    Authors: Eunae Cho, Sang Woo Park, Chung Hwan Jun, Sang Soo Shin, Eun Kyu Park, Kyo Seon Lee, Seon Young Park, Chang Hwan Park, Hyun Soo Kim, Sung Kyu Choi and Jong Sun Rew

    Citation: BMC Infectious Diseases 2018 18:40

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  17. Content type: Case report

    Eikenella corrodens is one of the HACEK bacteria constituting part of the normal flora of the oropharynx, however, still an uncommon pathogen. We report a case of a large Eikenella corrodens liver abscess with si...

    Authors: Anne Christine Nordholm, Ruth Ottilia Birgitta Vøgg, Henrik Permin and Terese Katzenstein

    Citation: BMC Infectious Diseases 2018 18:35

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  18. Content type: Research article

    Urinary tract infection (UTI) remains to be one of the most common infectious diseases diagnosed in developing countries. And a widespread use of antibiotics against uropathogens has led to the emergence of an...

    Authors: Wubalem Desta Seifu and Alemayehu Desalegn Gebissa

    Citation: BMC Infectious Diseases 2018 18:30

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  19. Content type: Research article

    Opportunistic infections due to Candida species occur frequently in cancer patients because of their inherent immunosuppression. The aim of the present study was to investigate the epidemiology of yeast species f...

    Authors: Narges Aslani, Ghasem Janbabaei, Mahdi Abastabar, Jacques F. Meis, Mahasti Babaeian, Sadegh Khodavaisy, Teun Boekhout and Hamid Badali

    Citation: BMC Infectious Diseases 2018 18:24

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  20. Content type: Research article

    Checklists are increasingly used to measure quality of care. Recently we implemented an antibiotic checklist in nine Dutch hospitals and showed that use of the checklist resulted in more appropriate antibiotic...

    Authors: Frederike V. van Daalen, Marlies E. J. L. Hulscher, Cas Minderhoud, Jan M. Prins and Suzanne E. Geerlings

    Citation: BMC Infectious Diseases 2018 18:16

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  21. Content type: Research article

    Group B Streptococcus (GBS) is a leading cause of morbidity and mortality in infants in both developed and developing countries. To our knowledge, only a few studies have been reported the clinical features, trea...

    Authors: Xiaoshan Guan, Xiaoping Mu, Wenjing Ji, Chunlei Yuan, Ping He, Lian Zhang, Yanfen Huang, Juan Li, Jianfeng Chen, Huamin Zhong, Shuyin Pang, Nan Tan, Qiulian Deng, Kankan Gao, Yu-Ping Huang, Chien-Yi Chang…

    Citation: BMC Infectious Diseases 2018 18:14

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  22. Content type: Research article

    The defense mechanisms of the urinary tract are attributed mainly to the innate immune system and the urinary tract urothelium which represent the first line of defense against invading pathogens and maintaini...

    Authors: Ibrahim H. Babikir, Elsir A. Abugroun, Naser Eldin Bilal, Abdullah Ali Alghasham, Elmuataz Elmansi Abdalla and Ishag Adam

    Citation: BMC Infectious Diseases 2018 18:17

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  23. Content type: Research article

    Acinetobacter baumannii (AB) is critical for healthcare-associated infections (HAI) with significant regional differences in the resistance rate, but its risk factors and infection trends has not been well studie...

    Authors: Huiping Huang, Borong Chen, Gang Liu, Jing Ran, Xianyu Lian, Xinhua Huang, Nan Wang and Zhengjie Huang

    Citation: BMC Infectious Diseases 2018 18:11

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  24. Content type: Research article

    Previous studies on the Burkholderia pseudomallei genetic diversity among clinical isolates from melioidosis-endemic areas have identified genetic factors contributing to differential virulence. Although it has b...

    Authors: Abdel Rahman Zueter, Zaidah Abdul Rahman, Mahmoud Abumarzouq and Azian Harun

    Citation: BMC Infectious Diseases 2018 18:5

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  25. Content type: Research article

    Longtime follow-up studies on patients with pharyngotonsillitis are rare. We aimed to describe the patterns of new visits for a sore throat, complications and tonsillectomy during 2 years in a cohort of patien...

    Authors: Jon Pallon, Martin Sundqvist and Katarina Hedin

    Citation: BMC Infectious Diseases 2018 18:3

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  26. Content type: Research article

    Streptococcus pneumoniae, the leading pathogen of bacterial infections in infants and the elderly, is responsible for pneumococcal diseases with severe morbidity and mortality. Emergence of d...

    Authors: Chunjiang Zhao, Zongbo Li, Feifei Zhang, Xiaobing Zhang, Ping Ji, Ji Zeng, Bijie Hu, Zhidong Hu, Kang Liao, Hongli Sun, Rong Zhang, Bin Cao, Chao Zhuo, Wei Jia, Yaning Mei, Yunzhuo Chu…

    Citation: BMC Infectious Diseases 2017 17:804

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  27. Content type: Research article

    Voriconazole has been used in the treatment and prophylaxis of invasive fungal infections (IFIs) while its wide use was limited by some frequent adverse events, especially neurotoxicity, hepatotoxicity and eve...

    Authors: Yuanming Xing, Lu Chen, Yan Feng, Yan Zhou, Yajing Zhai and Jun Lu

    Citation: BMC Infectious Diseases 2017 17:798

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  28. Content type: Case report

    Invasive aspergillosis involving patients with neutropenia or severe immunosuppression, such as patients with hematologic malignancies is associated with high mortality. Patients with T-cell large granular lym...

    Authors: Amin T. Turki, Jassin Rashidi-Alavijeh, Jan Dürig, Guido Gerken, Peter-Michael Rath and Oliver Witzke

    Citation: BMC Infectious Diseases 2017 17:797

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  29. Content type: Research article

    Vertical transmission can result in neonatal infection and disease. Reducing the transmission of bacterial pathogens from mother to infant may be an effective means of preventing neonatal infection, including ...

    Authors: Sarah E. Burr, Bully Camara, Claire Oluwalana, Ebrima Bojang, Christian Bottomley, Abdoulie Bojang, Robin L. Bailey, Umberto D’Alessandro and Anna Roca

    Citation: BMC Infectious Diseases 2017 17:799

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  30. Content type: Research article

    To investigate the clinical characteristics and treatment outcomes in necrotizing fasciitis (NF) patients in a reconstructive unit in northeastern China.

    Authors: Jing-Chun Zhao, Bo-Ru Zhang, Kai Shi, Xi Zhang, Chun-Hui Xie, Jian Wang, Qing-Hua Yu, Xin-Xin Gao, Lei Hong and Jia-Ao Yu

    Citation: BMC Infectious Diseases 2017 17:792

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  31. Content type: Research article

    Studies have shown that radiation from radiotherapy increases the yeast colonization of patients. However it is not clear, if such radiation alters the yeast itself. The aim of the present study was therefore ...

    Authors: Eliane Martins da Silva, Elaine Sciuniti Benites Mansano, Ellen Sayuri Miazima, Francielle Abigail Vilugron Rodrigues, Luzmarina Hernandes and Terezinha Inez Estivalet Svidzinski

    Citation: BMC Infectious Diseases 2017 17:783

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  32. Content type: Research article

    Co-infections are common in childhood community acquired pneumonia (CAP). However, their etiological pattern and clinical impact remains inconclusive.

    Authors: Wujun Jiang, Min Wu, Jing Zhou, Yuqing Wang, Chuangli Hao, Wei Ji, Xinxing Zhang, Wenjing Gu and Xuejun Shao

    Citation: BMC Infectious Diseases 2017 17:787

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  33. Content type: Research article

    To evaluate in vitro susceptibilities of aerobic and facultative Gram-negative bacterial (GNB) isolates from intra-abdominal infections (IAIs) to 12 selected antimicrobials in Chinese hospitals from 2012 to 2014.

    Authors: Hui Zhang, Qiwen Yang, Kang Liao, Yuxing Ni, Yunsong Yu, Bijie Hu, Ziyong Sun, Wenxiang Huang, Yong Wang, Anhua Wu, Xianju Feng, Yanping Luo, Yunzhuo Chu, Shulan Chen, Bin Cao, Jianrong Su…

    Citation: BMC Infectious Diseases 2017 17:776

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  34. Content type: Research article

    Diarrheagenic Escherichia coli (DEC) are important bacterial causes of childhood diarrhea in Brazil, but its impact in adults is unknown. This study aimed at investigating DEC among children and adults living in ...

    Authors: Liliana Cruz Spano, Keyla Fonseca da Cunha, Mariane Vedovatti Monfardini, Rita de Cássia Bergamaschi Fonseca and Isabel Christina Affonso Scaletsky

    Citation: BMC Infectious Diseases 2017 17:773

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  35. Content type: Case report

    Streptococcus pyogenes (group A Streptococcus [GAS]) is a major human pathogen that causes a wide spectrum of clinical manifestations. Although invasive GAS (iGAS) infections are relat...

    Authors: Tsuyoshi Sekizuka, Emina Nai, Tomohiro Yoshida, Shota Endo, Emi Hamajima, Satoka Akiyama, Yoji Ikuta, Natsuko Obana, Takahiro Kawaguchi, Kenta Hayashi, Masahiro Noda, Tomoko Sumita, Masayuki Kokaji, Tatsuo Katori, Masanori Hashino, Kunihiro Oba…

    Citation: BMC Infectious Diseases 2017 17:774

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  36. Content type: Research article

    In sub-Saharan Africa, efforts to control antimicrobial resistance (AMR) are aggravated by unregulated drug sales and use, and high connectivity between human, livestock, and wildlife populations. Our previous...

    Authors: Casey J. Roulette, Mark A. Caudell, Jennifer W. Roulette, Robert J. Quinlan, Marsha B. Quinlan, Murugan Subbiah and Douglas R. Call

    Citation: BMC Infectious Diseases 2017 17:770

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  37. Content type: Research article

    The clinical manifestation of pulmonary cryptococcosis varies notably between immunocompromised and immunocompetent patients. To better understand pulmonary cryptococcosis, we compared the clinical features of...

    Authors: Qian He, Yuan Ding, Wei Zhou, Hongxing Li, Ming Zhang, Yi Shi and Xin Su

    Citation: BMC Infectious Diseases 2017 17:768

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  38. Content type: Case report

    Elizabethkingia miricola is a rare Gram-negative bacterium found in water and clinical specimens. Typical culturing methods often misidentify Elizabethkingia spp. as Flavobacterium or

    Authors: Przemysław Zdziarski, Mariola Paściak, Klaudia Rogala, Agnieszka Korzeniowska-Kowal and Andrzej Gamian

    Citation: BMC Infectious Diseases 2017 17:763

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  39. Content type: Research article

    Speeding up identification and antimicrobial susceptibility testing (AST) is of foremost importance in the management of blood cultures. Here, we describe a simple, rapid, and standardized approach based on a ...

    Authors: Carola Mauri, Luigi Principe, Silvia Bracco, Elisa Meroni, Nicoletta Corbo, Beatrice Pini and Francesco Luzzaro

    Citation: BMC Infectious Diseases 2017 17:749

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  40. Content type: Research article

    The mortality of Candida Bloodstream Infection (CBSI) remains high. Antifungal susceptibility breakpoints were recently updated for Candida species, the impact remains unknown. In this study we evaluated the impa...

    Authors: María Fernanda González-Lara, Pedro Torres-González, Patricia Cornejo-Juárez, Consuelo Velázquez-Acosta, Areli Martinez-Gamboa, Andrea Rangel-Cordero, Miriam Bobadilla-del-Valle, Luis Ostrosky-Zeichner, Alfredo Ponce-de-León and José Sifuentes-Osornio

    Citation: BMC Infectious Diseases 2017 17:753

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  41. Content type: Case report

    We report the first adult case of Neisseria meningitidis W-135 presenting with meningococcal arthritis and myopericarditis concomitantly, without other classical features of meningococcal disease.

    Authors: Lloyd Steele, Katie Bechman, Eoghan De Barra and Charles Mackworth-Young

    Citation: BMC Infectious Diseases 2017 17:751

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  42. Content type: Research article

    As several studies indicated an increase in Lyme disease (LD), notably in neighbouring countries, concerns have arisen regarding the evolution of Lyme disease in Belgium. In order to confirm or infirm the incr...

    Authors: Mathilde De Keukeleire, Sophie O. Vanwambeke, Benoît Kabamba, Leila Belkhir, Philippe Pierre, Victor Luyasu and Annie Robert

    Citation: BMC Infectious Diseases 2017 17:748

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  43. Content type: Research article

    Lyme borreliosis (LB) is the most common reported tick-borne infection in Europe, and involves transmission of Borrelia by ticks. As long as a vaccine is not available and effective measures for controlling tick ...

    Authors: L. Antonise-Kamp, D. J. M. A. Beaujean, R. Crutzen, J. E. van Steenbergen and D. Ruwaard

    Citation: BMC Infectious Diseases 2017 17:744

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  44. Content type: Research article

    In the eighties, a multidrug resistant clone of Salmonella Typhimurium DT104 emerged in UK and disseminated worldwide. This clone harbored a Salmonella genomic island 1 (SGI1) that consists of a backbone and a mu...

    Authors: Claire de Curraize, Lucie Amoureux, Julien Bador, Angélique Chapuis, Eliane Siebor, Claire Clément, Juliette Sauge, Ludwig-Serge Aho-Glélé and Catherine Neuwirth

    Citation: BMC Infectious Diseases 2017 17:741

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  45. Content type: Research article

    Resistant staphylococcal organisms remain a serious problem in the treatment of periprosthetic joint infection (PJI). Higher failure rates have been reported when vancomycin was used. The purpose of this study...

    Authors: Yu-Jui Chang, Mel S. Lee, Chen-Hsiang Lee, Po-Chun Lin and Feng-Chih Kuo

    Citation: BMC Infectious Diseases 2017 17:736

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  46. Content type: Research article

    Staphylococcus aureus (S. aureus) is a major pathogen implicated in skin and soft tissue infections, abscess in deep organs, toxin mediated diseases, respiratory tract infections, urin...

    Authors: Haji Mohammad Naimi, Hamidullah Rasekh, Ahmad Zia Noori and Mohammad Aman Bahaduri

    Citation: BMC Infectious Diseases 2017 17:737

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