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Bacterial and fungal diseases

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of bacterial and fungal diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section includes studies relating to antibiotic resistance and healthcare-associated infections.

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  1. Risk factors related to mortality due to invasive pneumococcal disease (IPD) have been unveiled previously, but early clinical manifestations of IPD based on prognosis remain uncovered.

    Authors: Shuiyan Wu, Xubei Guo, Zhong Xu, Meilin Han, Lili Huang, Yunzhen Tao, Ying Li, Yanhong Li, Tao Zhang and Zhenjiang Bai

    Citation: BMC Infectious Diseases 2020 20:651

    Content type: Research article

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  2. Cryptococcus is a conditional pathogenic fungus causing cryptococcosis, which is one of the most serious fungal diseases faced by humans. Lateral flow immunochromatographic assay (LFA) is successfully applied to ...

    Authors: Li-Min Xie, Geng-Ling Lin, Hao-Neng Dong, Ying-Xia Liao, Ye-Ling Liu, Jian-Feng Qin and Xu-Guang Guo

    Citation: BMC Infectious Diseases 2020 20:650

    Content type: Research article

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  3. COVID-19 is known as a new viral infection. Viral-bacterial co-infections are one of the biggest medical concerns, resulting in increased mortality rates. To date, few studies have investigated bacterial super...

    Authors: Ehsan Sharifipour, Saeed Shams, Mohammad Esmkhani, Javad Khodadadi, Reza Fotouhi-Ardakani, Alireza Koohpaei, Zahra Doosti and Samad EJ Golzari

    Citation: BMC Infectious Diseases 2020 20:646

    Content type: Research article

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  4. The transmission features and the feasibility of containing shigellosis remain unclear among a population-based study in China.

    Authors: Jia Rui, Qi Chen, Qiuping Chen, Qingqing Hu, Mikah Ngwanguong Hannah, Zeyu Zhao, Yao Wang, Xingchun Liu, Zhao Lei, Shanshan Yu, Yi-Chen Chiang, Benhua Zhao, Yanhua Su, Bin Zhao and Tianmu Chen

    Citation: BMC Infectious Diseases 2020 20:643

    Content type: Research article

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  5. Data regarding the prevalence of metallo-β-lactamases (MBLs) among Pseudomonas aeruginosa isolates in cystic fibrosis patients are scarce. Furthermore, there is limited knowledge on the effect of MBL production o...

    Authors: M. Carugati, A. Piazza, A. M. Peri, L. Cariani, M. Brilli, D. Girelli, D. Di Carlo, A. Gramegna, M. Pappalettera, F. Comandatore, G. Grasselli, A. P. Cantù, M. Arghittu, A. Gori, C. Bandi, F. Blasi…

    Citation: BMC Infectious Diseases 2020 20:635

    Content type: Case report

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  6. People who inject drugs (PWID) have increased risk of acquiring blood-transmitted chronic viral infections such as Hepatitis B (HBV), Hepatitis C (HCV) and Human Immunodeficiency Virus (HIV) as well as increas...

    Authors: Sara Thønnings, Filip Jansåker, Christoffer Sundqvist, Rebekka Faber Thudium, Susanne Dam Nielsen and Jenny Dahl Knudsen

    Citation: BMC Infectious Diseases 2020 20:634

    Content type: Research article

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  7. Cases of refractory Mycoplasma pneumoniae pneumonia have been increasing recently; however, whether viral coinfection or macrolide-resistant M. infection contribute to the development of refractory M. pneumoniae ...

    Authors: Yajuan Zhou, Jing Wang, Wenjuan Chen, Nan Shen, Yue Tao, Ruike Zhao, Lijuan Luo, Biru Li and Qing Cao

    Citation: BMC Infectious Diseases 2020 20:633

    Content type: Research article

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  8. There is evidence that males have higher incidence rates (IR) of campylobacteriois than females. The objectives of this study were to determine whether these observations differ between age groups and are cons...

    Authors: Manfred S. Green, Naama Schwartz and Victoria Peer

    Citation: BMC Infectious Diseases 2020 20:625

    Content type: Research article

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  9. We aimed to describe an outbreak of cutaneous abscesses caused by Panton-Valentine leukocidin (PVL)-producing methicillin-susceptible Staphylococcus aureus (MSSA) among gold mine workers.

    Authors: Husna Ismail, Nelesh P. Govender, Ashika Singh-Moodley, Erika van Schalkwyk, Liliwe Shuping, Itumeleng Moema, Gal Feller, Ruth Mogokotleng, Wilhelmina Strasheim, Michelle Lowe, Ruth Mpembe, Serisha Naicker, Tsidiso G. Maphanga, Cecilia De Abreu, Farzana Ismail, Nazir Ismail…

    Citation: BMC Infectious Diseases 2020 20:621

    Content type: Research article

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  10. Neisseria macacae was discovered in the oral cavity of monkeys in 1983. In humans, it has been isolated from the upper respiratory tract of neutropenic patients. However, only two cases of N. macacae bacteremia h...

    Authors: Yasumasa Yamamoto, Norihiko Terada, Tomoyo Sugiyama, Hanako Kurai and Kiyofumi Ohkusu

    Citation: BMC Infectious Diseases 2020 20:619

    Content type: Case report

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  11. Vibrio cholerae are oxidase-positive bacteria that are classified into various serotypes based on the O surface antigen. V. cholerae serotypes are divided into two main groups: the O1 and O139 group and the non-O...

    Authors: Keisuke Tsuruta, Toru Ueyama, Tomoo Watanabe, Kenichi Nakano, Kenji Uno and Hidetada Fukushima

    Citation: BMC Infectious Diseases 2020 20:618

    Content type: Case report

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  12. The rise in antibiotic resistance is a global public health concern, and antibiotic overuse needs to be reduced. Earlier studies of out-of-hours care have indicated that antibiotic prescribing is less appropri...

    Authors: Olof Cronberg, Mia Tyrstrup, Kim Ekblom and Katarina Hedin

    Citation: BMC Infectious Diseases 2020 20:616

    Content type: Research article

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  13. The global prevalent ptxP3 strains varies from about 10% to about 50% of circulating B. pertussis population in different areas of China.

    Authors: Zengguo Wang, Yang Luan, Quanli Du, Chang Shu, Xiaokang Peng, Huijing Wei, Tiejun Hou, Ying Liu, Xiaoguai Liu and Yarong Li

    Citation: BMC Infectious Diseases 2020 20:615

    Content type: Research article

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  14. The most common aetiological agents of mucormycosis are Rhizopus, Mucor, Apophysomyces and Lichtheimia. Apophysomyces is comparatively rare, as it has been reported in less than 3% of mucormycosis cases. The genu...

    Authors: Erick Martínez-Herrera, María Guadalupe Frías-De-León, Angélica Julián-Castrejón, Luis Cruz-Benítez, Juan Xicohtencatl-Cortes and Rigoberto Hernández-Castro

    Citation: BMC Infectious Diseases 2020 20:614

    Content type: Case report

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  15. Strongyloidiasis is caused by the helminth Strongyloides stercoralis and is well-recognised amongst transplant recipients. Serious complications, including Strongyloides hyperinfection which is a syndrome of acce...

    Authors: Christina Lai, Matthew Anderson, Rebecca Davis, Lyndal Anderson, Kate Wyburn, Steve Chadban and David Gracey

    Citation: BMC Infectious Diseases 2020 20:613

    Content type: Case report

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  16. Chronic obstructive pulmonary disease (COPD) is one of the most prevalent diseases worldwide. Episodes of acute exacerbations of COPD (AECOPD) are associated with disease severity and progression. Although sub...

    Authors: Juan Wang, Jianmin Chai, Lina Sun, Jiangchao Zhao and Chun Chang

    Citation: BMC Infectious Diseases 2020 20:610

    Content type: Research article

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  17. This study aimed to identify ten different 16S rRNA methyltransferase genes (rmtA, rmtB, rmtC, rmtD, armA, rmtF, npmA, rmtH, rmtE and rmtG) and their coexisting ESBL and carbapenemase with the emergence of three

    Authors: Jayalaxmi Wangkheimayum, Mohana Bhattacharjee, Bhaskar Jyoti Das, K. Melson Singha, Debadatta Dhar Chanda and Amitabha Bhattacharjee

    Citation: BMC Infectious Diseases 2020 20:544

    Content type: Research article

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    The Correction to this article has been published in BMC Infectious Diseases 2020 20:620

  18. Invasive fungal pneumonia is a severe infectious disease with high mortality in immunocompromised patients. However, the clinical diagnosis of the pathogen(s) remains difficult since microbiological evidence i...

    Authors: Kaiyu Zhang, Chen Yu, Yuxiang Li and Yang Wang

    Citation: BMC Infectious Diseases 2020 20:608

    Content type: Case report

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  19. Infectious Diseases Society of America (IDSA) guidelines suggest 7–14 days’ duration of antibiotic treatment for uncomplicated Gram-negative bacteria (GNB) catheter-related bloodstream infection (CRBSI). The o...

    Authors: Bhitta Surapat, Preecha Montakantikul, Kumthorn Malathum, Sasisopin Kiertiburanakul, Pitak Santanirand and Busba Chindavijak

    Citation: BMC Infectious Diseases 2020 20:604

    Content type: Research article

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  20. The objectives of this study were to determine for the first time, in Morocco, the nasal carriage rate, antimicrobial susceptibility profiles and virulence genes of Staphylococcus. aureus isolated from animals an...

    Authors: Nadira Mourabit, Abdelhay Arakrak, Mohammed Bakkali, Zeineb Zian, Joaira Bakkach and Amin Laglaoui

    Citation: BMC Infectious Diseases 2020 20:602

    Content type: Research article

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  21. Listeriosis is a rare but severe foodborne infectious disease. Perinatal listeriosis is often associated with septicemia, central nervous system (CNS) infection, and serious adverse pregnancy outcomes (miscarr...

    Authors: Chunyun Li, Huihui Zeng, Xin Ding, Yi Chen, Xiaowei Liu, Li Zhou, Xin Wang, Yumei Cheng, Shanshan Hu, Zheng Cao, Ruixia Liu and Chenghong Yin

    Citation: BMC Infectious Diseases 2020 20:601

    Content type: Research article

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  22. Fungal bloodstream infections (FBI) among intensive care unit (ICU) patients are increasing. Our objective was to characterize the fungal pathogens that cause bloodstream infections and determine the epidemiol...

    Authors: Guangwen Xiao, Wanqing Liao, Yuenong Zhang, Xiaodong Luo, Cailing Zhang, Guodan Li, Yingping Yang and Yunyao Xu

    Citation: BMC Infectious Diseases 2020 20:599

    Content type: Research article

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  23. Multidrug resistant (MDR) and extensively drug resistant (XDR) Acinetobacter baumannii presents challenges for clinical treatment and causes high mortality in children. We aimed to assess the risk factors and ove...

    Authors: Jingyi Shi, Ting Sun, Yun Cui, Chunxia Wang, Fei Wang, Yiping Zhou, Huijie Miao, Yijun Shan and Yucai Zhang

    Citation: BMC Infectious Diseases 2020 20:597

    Content type: Research article

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  24. Inappropriate and excessive antimicrobial prescribing can lead to antimicrobial resistance. Antimicrobial Stewardship (AMS) principles are not well established in general practice in Australia despite the rela...

    Authors: Alicia J. Neels, Aaron E. Bloch, Stella M. Gwini and Eugene Athan

    Citation: BMC Infectious Diseases 2020 20:586

    Content type: Research article

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  25. Listeriosis is a severe food-borne infection caused by the Gram-positive rod, Listeria monocytogenes. Despite the low incidence (3–8 cases per million), Listeriosis has a case fatality rate of 20–30% as it occurs...

    Authors: Rand Al Ohaly, Nischal Ranganath, Medina G. Saffie and Anjali Shroff

    Citation: BMC Infectious Diseases 2020 20:559

    Content type: Case report

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  26. Dengue fever is endemic and a leading health problem in Sri Lanka. Increased incidence of concurrent bacteremia in patients with dengue infection is a recognized complication. However, Staphylococcal endocardi...

    Authors: Nilusha Weerasooriya, Tharanga Fernando, Pasan Serasinghe, Buddhika Alahakoon, Chirath Madurapperuma and Ananda Jayanaga

    Citation: BMC Infectious Diseases 2020 20:583

    Content type: Case report

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  27. Gram-positive anaerobic (GPA) bacteria inhabit different parts of the human body as commensals but can also cause bacteremia. In this retrospective observational study, we analyzed GPA bacteremia pathogens bef...

    Authors: Tsuyoshi Watanabe, Yuki Hara, Yusuke Yoshimi, Yoshiro Fujita, Masamichi Yokoe and Yoshinori Noguchi

    Citation: BMC Infectious Diseases 2020 20:578

    Content type: Research article

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  28. The incidence of cryptococcal meningitis (CM) has gradually increased in recent years. Cerebrospinal fluid (CSF) cytology and cell count are very important for CM on etiology diagnosis and assessment of diseas...

    Authors: Junyan Qu, Jingwen Jiang and Xiaoju Lv

    Citation: BMC Infectious Diseases 2020 20:571

    Content type: Research article

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  29. Subtenon injection of triamcinolone acetonide (STTA) has been widely adopted in the clinical setting of ophthalmology and its infectious complications are rare. However, orbital abscess following STTA has been...

    Authors: Chiharu Iwahashi, Hiroshi Eguchi, Fumika Hotta, Mayu Uezumi, Miki Sawa, Masatomo Kimura, Takashi Yaguchi and Shunji Kusaka

    Citation: BMC Infectious Diseases 2020 20:566

    Content type: Case report

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  30. Morbidity and mortality in transplant patients is increased by infection caused mainly by rare opportunistic pathogens. The present study reports a case where Hongkongmyces snookiorum caused subcutaneous phaeohyp...

    Authors: Deng Linqiang, Chen Yiguo, Xu Heping, Chen Dongke, Hu Longhua, Gui Xiaomei and Zou Xia

    Citation: BMC Infectious Diseases 2020 20:562

    Content type: Case report

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  31. Extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-PE) infections are frequent and highly impact cancer patients. We developed and validated a scoring system to identify cancer patients harboring...

    Authors: Alvaro J. Martínez-Valencia, Brian J. Gómez Martínez, Anita M. Montañez Ayala, Katherin García, Ricardo Sánchez Pedraza, Leydy P. Jiménez Cetina, Julio C. Gómez Rincón and Sonia I. Cuervo Maldonado

    Citation: BMC Infectious Diseases 2020 20:558

    Content type: Research article

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  32. Multi-drug resistance pathogens such as Extended-Spectrum Beta-Lactamase (ESBL) producing Enterobacteriaceae (ESBL-PE) are of great global health concern, since they are associated with increased morbidity and...

    Authors: Upendo O. Kibwana, Mtebe Majigo, Doreen Kamori and Joel Manyahi

    Citation: BMC Infectious Diseases 2020 20:557

    Content type: Research article

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  33. To evaluate whether soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) can be used as an early predictor of ventilator-associated pneumonia (VAP).

    Authors: Xingxing Zhao, Lixiao Xu, Zuming Yang, Bin Sun, Ying Wang, Gen Li, Chenxi Feng, Tao Pan, Tian Yu and Xing Feng

    Citation: BMC Infectious Diseases 2020 20:542

    Content type: Research article

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  34. Antimicrobial resistance is an ecological and multicausal problem. Infections caused by extended-spectrum β-lactamase producing Enterobacteriaceae (ESBL-E) can be acquired and transmitted in the community. Data o...

    Authors: Deving Arias Ramos, Julián Andrés Hoyos Pulgarín, Germán Alberto Moreno Gómez, John Alexander Alzate, Juan Camilo Olaya Gómez, Isabella Cortés Bonilla and Camila Vargas Mosquera

    Citation: BMC Infectious Diseases 2020 20:540

    Content type: Research article

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  35. Breakthrough invasive fungal infections (bIFIs) are an area of concern in the scarcity of new antifungals. The mixed form of bIFIs is a rare phenomenon but could be potentially a troublesome challenge when cau...

    Authors: Ali Amanati, Mehrzad Lotfi, Mohammad Sadegh Masoudi, Hadis Jafarian, Fatemeh Ghasemi, Haleh Bozorgi and Parisa Badiee

    Citation: BMC Infectious Diseases 2020 20:535

    Content type: Case report

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  36. Conidiobolus spp. (mainly C. coronatus) are the causal agents of rhino-facial conidiobolomycosis, a limited soft tissue infection, which is essentially observed in immunocompetent individuals from tropical areas....

    Authors: E. Stavropoulou, A. T. Coste, C. Beigelman-Aubry, I. Letovanec, O. Spertini, A. Lovis, T. Krueger, R. Burger, P. Y. Bochud and F. Lamoth

    Citation: BMC Infectious Diseases 2020 20:527

    Content type: Case report

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  37. Neisseria meningitidis is a major cause of bacterial meningitis, and these infections are associated with a high mortality rate. Rapid and reliable diagnosis of bacterial meningitis is critical in clinical practi...

    Authors: Shu-Jin Fan, Hong-Kun Tan, Yu-Cheng Xu, Yuan-Zhi Chen, Tian-Ao Xie, Zhi-Yong Pan, Shi Ouyang, Qin Li, Xiao-yan Li, Zhen-Xing Li and Xu-Guang Guo

    Citation: BMC Infectious Diseases 2020 20:525

    Content type: Research article

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    The Correction to this article has been published in BMC Infectious Diseases 2020 20:560

  38. Assessing the burden of rickettsial infections in Ontario, Canada, is challenging since rickettsial infections are not reportable to public health. In the absence of reportable disease data, we assessed the bu...

    Authors: Mark P. Nelder, Curtis B. Russell, Steven Johnson, Ye Li, Kirby Cronin, Bryna Warshawsky, Nicholas Brandon and Samir N. Patel

    Citation: BMC Infectious Diseases 2020 20:523

    Content type: Research article

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  39. The widespread administration of the Haemophilus influenzae type b vaccine has led to the predominance of non-typable H. influenzae (NTHi). However, the occurrence of invasive NTHi infection based on gynecologic ...

    Authors: Yoshito Nishimura, Hideharu Hagiya, Kaoru Kawano, Yuya Yokota, Kosuke Oka, Koji Iio, Kou Hasegawa, Mikako Obika, Tomoko Haruma, Sawako Ono, Hisashi Masuyama and Fumio Otsuka

    Citation: BMC Infectious Diseases 2020 20:521

    Content type: Case report

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  40. Campylobacter jejuni is a leading cause of bacterial diarrhea worldwide, and increasing rates of fluoroquinolone (FQ) resistance in C. jejuni are a major public health concern. The rapid detection and tracking of...

    Authors: Nereyda Espinoza, Jesús Rojas, Simon Pollett, Rina Meza, Lilian Patiño, Manuel Leiva, Máximo Camiña, Manuela Bernal, Nathanael D. Reynolds, Ryan Maves, Drake H. Tilley, Matthew Kasper and Mark P. Simons

    Citation: BMC Infectious Diseases 2020 20:518

    Content type: Research article

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  41. The role of ultrasonography-guided percutaneous fine-needle aspiration (PNA) for pyogenic liver abscess (PLA) remains without consensus, especially in abscesses 3 to 6 cm in diameter. The objective of this stu...

    Authors: Shuangjun He, Jie Yu, Hairong Wang, Xuelian Chen, Zhanqiang He and Yi Chen

    Citation: BMC Infectious Diseases 2020 20:516

    Content type: Research article

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  42. The aims of this study were to identify the predictive factors for microbiological diagnosis through disco-vertebral biopsy (DVB) in patients with pyogenic vertebral osteomyelitis (PVO) and negative blood cult...

    Authors: Caroline Diffre, Camille Jousset, Anne-Laure Roux, Clara Duran, Latifa Noussair, Martin Rottman, Robert-Yves Carlier and Aurélien Dinh

    Citation: BMC Infectious Diseases 2020 20:512

    Content type: Research article

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  43. Salmonella enterica subsp. enterica serovar Typhimurium infections continue to be a significant public health threat worldwide. The aim of this study was to investigate antibiotic resistance among 147 S. Typhimur...

    Authors: Nian Dong, Yongrui Li, Jiayong Zhao, Hui Ma, Jinyan Wang, Beibei Liang, Xinying Du, Fuli Wu, Shengli Xia, Xiaoxia Yang, Hongbo Liu, Chaojie Yang, Shaofu Qiu, Hongbin Song, Leili Jia, Yan Li…

    Citation: BMC Infectious Diseases 2020 20:511

    Content type: Research article

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  44. Group A streptococcus (GAS) is an important human pathogen responsible for a broad range of infections. Epidemiological surveillance has been crucial to detect changes in the geographical and temporal variatio...

    Authors: Hongxin Li, Lin Zhou, Yong Zhao, Lijuan Ma, Xiaoyan Liu and Jin Hu

    Citation: BMC Infectious Diseases 2020 20:507

    Content type: Research article

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  45. Meningococcal meningitis (MM) is a life-threatening disease associated with approximately 10% case fatality rates and neurological sequelae in 10–20% of the cases. Recently, we have shown that the matrix metal...

    Authors: Susanna Ricci, Denis Grandgirard, Ilias Masouris, Tiziana Braccini, Gianni Pozzi, Marco R. Oggioni, Uwe Koedel and Stephen L. Leib

    Citation: BMC Infectious Diseases 2020 20:505

    Content type: Research article

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  46. Streptomyces cacaoi, Gram-positive, branched, filamentous bacillus forms without fragmentation, are saprophytic soil organisms rarely known to cause invasive infections other than mycetoma. Here we describe a cas...

    Authors: Lu Ai, Han Huang, Zhongwen Wu, Pingjuan Liu, Jianyu Huang and Yili Chen

    Citation: BMC Infectious Diseases 2020 20:499

    Content type: Case report

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