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Bacterial and fungal diseases

Section edited by Ivan FN Hung, Jorge Garbino and Kelvin To

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of bacterial and fungal diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section includes studies relating to antibiotic resistance and healthcare-associated infections.

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  1. Content type: Research article

    Gram-positive organisms are a leading cause of infection in cardiovascular surgery. Furthermore, these patients have a high risk of developing postoperative renal failure in intensive care unit (ICU). Some ant...

    Authors: Philippe Gaudard, Marine Saour, David Morquin, Hélène David, Jacob Eliet, Maxime Villiet, Jean-Pierre Daures and Pascal Colson

    Citation: BMC Infectious Diseases 2019 19:438

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  2. Content type: Research article

    Staphylococcus aureus (S. aureus) is a common cause of bacteremia, which leads to significant morbidity and mortality. We investigated the relationship between time to positivity (TTP) and clinical outcomes in ch...

    Authors: Yuanyuan Li, Qinyuan Li, Guangli Zhang, Huan Ma, Yi Wu, Qian Yi, Lili Jiang, Jiao Wan, Fengtao Suo and Zhengxiu Luo

    Citation: BMC Infectious Diseases 2019 19:437

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    The Correction to this article has been published in BMC Infectious Diseases 2019 19:608

  3. Content type: Research article

    Four species within Anaplasma genus are emerging zoonotic pathogens, which are transmitted by ticks and generate veterinary and public health concerns. Here, we performed a molecular survey of Anaplasma in Ankang...

    Authors: Wen-Ping Guo, Bing Zhang, Yi-Han Wang, Gang Xu, Xiaoquan Wang, Xuebing Ni and En-Min Zhou

    Citation: BMC Infectious Diseases 2019 19:434

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  4. Content type: Research article

    Determining the etiology of pneumonia is essential to guide public health interventions. Diagnostic test results, including from polymerase chain reaction (PCR) assays of upper respiratory tract specimens, hav...

    Authors: Ying Lu, Lawrence Joseph, Patrick Bélisle, Pongpun Sawatwong, Anchalee Jatapai, Toni Whistler, Somsak Thamthitiwat, Wantana Paveenkittiporn, Supphacoke Khemla, Chris A. Van Beneden, Henry C. Baggett and Christopher J. Gregory

    Citation: BMC Infectious Diseases 2019 19:423

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  5. Content type: Research article

    Urinary tract infection is an infection affecting infants and children. The aim of this study was to determine the etiology of urinary tract infection along with their antimicrobial resistance.

    Authors: Rabina Ganesh, Dhiraj Shrestha, Balkrishna Bhattachan and Ganesh Rai

    Citation: BMC Infectious Diseases 2019 19:420

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  6. Content type: Research article

    In Ethiopia, morbidity and mortality due to diarrhea is significantly high. Most importantly, burden of diarrhea is disproportionately high among under-five children. Therefore, the objective of this study was...

    Authors: Amare Belachew Dagnew, Tilahun Tewabe, Yihun Miskir, Tariku Eshetu, Wosin Kefelegn, Kidanu Zerihun, Mekonnen Urgessa and Tiruha Teka

    Citation: BMC Infectious Diseases 2019 19:417

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  7. Content type: Research article

    Establishing epidemiological models and conducting predictions seems to be useful for the prevention and control of human brucellosis. Autoregressive integrated moving average (ARIMA) models can capture the lo...

    Authors: Wei Wu, Shu-Yi An, Peng Guan, De-Sheng Huang and Bao-Sen Zhou

    Citation: BMC Infectious Diseases 2019 19:414

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  8. Content type: Research article

    Implementation of sputum Gram stain in the initial assessment of community-acquired pneumonia (CAP) patients is still controversial. We performed a systematic review and meta-analysis to investigate the useful...

    Authors: Gaspar Del Rio-Pertuz, Juan F. Gutiérrez, Abel J. Triana, Jorge L. Molinares, Andrea B. Robledo-Solano, José L. Meza, Orlando M. Ariza-Bolívar, Jorge Acosta-Reyes, Argenis Garavito, Diego Viasus and Jordi Carratalà

    Citation: BMC Infectious Diseases 2019 19:403

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  9. Content type: Research article

    There have been no reports regarding clinical features and molecular characteristics of childhood methicillin-susceptible Staphylococcus aureus (MSSA) infections in Taiwan.

    Authors: Yu-Jen Chen, Po-An Chen, Chih-Jung Chen and Yhu-Chering Huang

    Citation: BMC Infectious Diseases 2019 19:402

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  10. Content type: Case report

    Leptospirosis or Weil’s disease is caused by pathogenic spirochete bacteria called Leptospira. It is considered the most common zoonosis in the world and is usually transmitted by urine of rodents and dogs with a...

    Authors: Alexander Maier, Rafael Kaeser, Robert Thimme and Tobias Boettler

    Citation: BMC Infectious Diseases 2019 19:395

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  11. Content type: Case report

    Ewingella americana (Ea) is a Gram-negative, lactose-fermenting, oxidase-negative and catalase-positive bacterium that was first described in 1983 as a new genus and species in the family Enterobacteriaceae. It i...

    Authors: Susanna Esposito, Francesco Miconi, Daniela Molinari, Emanuela Savarese, Federica Celi, Livio Marchese, Sara Valloscuro, Giovanni Miconi and Nicola Principi

    Citation: BMC Infectious Diseases 2019 19:386

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  12. Content type: Research article

    An outbreak of Candida auris began globally in 2014 including Pakistan and since then it has emerged as a nosocomial multi-drug resistant pathogen. The aim of this study was to assess the clinical spectrum and ou...

    Authors: Muneeba Ahsan Sayeed, Joveria Farooqi, Kausar Jabeen, Safia Awan and Syed Faisal Mahmood

    Citation: BMC Infectious Diseases 2019 19:384

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  13. Content type: Research article

    Climate change is expected to increase the chance of extreme rainfall events in the Northern Hemisphere and herewith, there is an increased chance of urban pluvial flooding. Urban pluvial flooding often consis...

    Authors: Annemieke Christine Mulder, Roan Pijnacker, Heleen de Man, Jan van de Kassteele, Wilfrid van Pelt, Lapo Mughini-Gras and Eelco Franz

    Citation: BMC Infectious Diseases 2019 19:377

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  14. Content type: Research article

    Urinary tract infections (UTIs) are one of the most common bacterial infections. High recurrence rates and the increasing antibiotic resistance among uropathogens constitute a large social and economic problem...

    Authors: Urszula Wnorowska, Ewelina Piktel, Bonita Durnaś, Krzysztof Fiedoruk, Paul B. Savage and Robert Bucki

    Citation: BMC Infectious Diseases 2019 19:369

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  15. Content type: Research article

    Whilst previous work has identified clustering of the active trachoma sign “trachomatous inflammation—follicular” (TF), there is limited understanding of the spatial structure of trachomatous trichiasis (TT), ...

    Authors: Rebecca Mann Flueckiger, Emanuele Giorgi, Jorge Cano, Mariamo Abdala, Olga Nelson Amiel, Gilbert Baayenda, Ana Bakhtiari, Wilfrid Batcho, Kamal Hashim Bennawi, Michael Dejene, Balgesa Elkheir Elshafie, Aba Ange Elvis, Missamou François, André Goepogui, Khumbo Kalua, Biruck Kebede…

    Citation: BMC Infectious Diseases 2019 19:364

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  16. Content type: Research article

    Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that is widely identified worldwide. This study aimed to investigate the phenotypic characterization and molecular typing of Clostridium difficile is...

    Authors: Parisa Shoaei, Hasan Shojaei, Mohammad Jalali, Farzin Khorvash, Sayed Mohsen Hosseini, Behrooz Ataei, Bahareh Vakili, Fatemeh Ebrahimi, Hossein Tavakoli, Zahra Esfandiari and J. Scott Weese

    Citation: BMC Infectious Diseases 2019 19:361

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  17. Content type: Case report

    Necrotizing fasciitis is a deep infection of the fascia and subcutaneous tissue with a high mortality rate. Meningitis is an infection of the membranes surrounding the brain with a likewise high mortality rate. S...

    Authors: Nichlas Hovmand, Sarah Byberg, Morten Bo Larsen, Daria Podlekareva, David Levarett Buck and Birgitte Rønde Hansen

    Citation: BMC Infectious Diseases 2019 19:358

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  18. Content type: Research article

    In developing countries particularly in sub-Saharan Africa trachoma is still a public health concern. Ethiopia is the most affected of all and bears the highest burden of active trachoma. In spite of this, the...

    Authors: Kemal Kassim, Jeylan Kassim, Rameto Aman, Mohammedawel Abduku, Mekonnen Tegegne and Biniyam Sahiledengle

    Citation: BMC Infectious Diseases 2019 19:353

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  19. Content type: Case report

    Brevibacteria are obligate aerobic gram-positive rods that are associated with milk products and are also found on human skin. Brevibacterium has been reported as a rare cause of catheter related blood steam infe...

    Authors: Nobuhiro Asai, Hiroyuki Suematsu, Atsuko Yamada, Hiroki Watanabe, Naoya Nishiyama, Daisuke Sakanashi, Hideo Kato, Arufumi Shiota, Mao Hagihara, Yusuke Koizumi, Yuka Yamagishi and Hiroshige Mikamo

    Citation: BMC Infectious Diseases 2019 19:344

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  20. Content type: Research article

    Ralstonia picketti, Ralstonia mannitolilytica, and Ralstonia insidiosa have recently been regarded as emerging pathogens of infectious diseases, in particular as the pathogens responsible for nosocomial infection...

    Authors: Qingqing Fang, Yu Feng, Ping Feng, Xiaohui Wang and Zhiyong Zong

    Citation: BMC Infectious Diseases 2019 19:334

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  21. Content type: Research article

    Invasive Salmonella infections result in significant morbidity and mortality in developing countries. In Asia, typhoid and paratyphoid fever are reported to be the major invasive Salmonella infections, while inva...

    Authors: Anand Mohan, Chandran Munusamy, Yee-Chin Tan, Sobana Muthuvelu, Rohaidah Hashim, Su-Lin Chien, Ming-Kui Wong, Nurul Aiman Khairuddin, Yuwana Podin, Peter Sie-Teck Lau, David Chun-Ern Ng and Mong-How Ooi

    Citation: BMC Infectious Diseases 2019 19:330

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  22. Content type: Case report

    Endograft infection is a rare but extremely dangerous complication of aortic repair (25–100% of mortality). We describe here the first case of Listeria monocytogenes abdominal periaortitis associated with a vascu...

    Authors: Aurélie Foulex, Matteo Coen, Abdessalam Cherkaoui, Vladimir Lazarevic, Nadia Gaïa, Stefano Leo, Myriam Girard, Damiano Mugnai and Jacques Schrenzel

    Citation: BMC Infectious Diseases 2019 19:326

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  23. Content type: Research article

    Group B streptococcus (GBS) is reported as the leading cause of neonatal sepsis and meningitis. Newborns from GBS colonized pregnant women are at high risk of infection.

    Authors: Musa Mohammed Ali, Yimtubezinash Woldeamanuel, Daniel Asrat Woldetsadik, Tolossa Eticha Chaka, Demissie Assegu Fenta, Muluwork Tefera Dinberu, Eskinder Kebede Weldetensaye, Samson Jamal Ismael and Birkneh Tilahun Tadesse

    Citation: BMC Infectious Diseases 2019 19:325

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  24. Content type: Study protocol

    After antibiotic treatment of Lyme borreliosis, a subset of patients report persistent symptoms, also referred to as post-treatment Lyme disease syndrome. The reported prevalence of persistent symptoms varies ...

    Authors: Hedwig D. Vrijmoeth, Jeanine Ursinus, Margriet G. Harms, Tizza P. Zomer, Stefanie A. Gauw, Anna D. Tulen, Kristin Kremer, Hein Sprong, Hans Knoop, Yolande M. Vermeeren, Barend van Kooten, Leo A. B. Joosten, Bart-Jan Kullberg, Joppe W. R. Hovius and Cees C. van den Wijngaard

    Citation: BMC Infectious Diseases 2019 19:324

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  25. Content type: Research article

    Despite major improvements in child survival rates, the number of deaths due to diarrhea remains unacceptably high. We aimed to describe diarrhea-associated mortality and evaluate risk factors for death among ...

    Authors: Sozinho Acácio, Inácio Mandomando, Tacilta Nhampossa, Llorenç Quintó, Delfino Vubil, Charfudin Sacoor, Karen Kotloff, Tamer Farag, Dilruba Nasrin, Eusébio Macete, Myron M. Levine, Pedro Alonso and Quique Bassat

    Citation: BMC Infectious Diseases 2019 19:322

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  26. Content type: Research article

    Necrotising fasciitis is a rapidly progressing soft-tissue infection with a low incidence that carries a relevant risk of morbidity and mortality. Although necrotising fasciitis is often fatal in adults, its c...

    Authors: Arne Schröder, Aurélie Gerin, Gregory B. Firth, Kelly S. Hoffmann, Andrew Grieve and Christina Oetzmann von Sochaczewski

    Citation: BMC Infectious Diseases 2019 19:317

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    The Correction to this article has been published in BMC Infectious Diseases 2019 19:469

  27. Content type: Research article

    Trimethoprim-sulfamethoxazole (TMP-SMX) is the drug of choice for anti-Pneumocystis jirovecii pneumonia (PcP) prophylaxis in kidney transplant recipients (KTR). Post-transplant management balances preventing PcP ...

    Authors: G. V. Ramesh Prasad, Jill Beckley, Mohit Mathur, Madhushankar Gunasekaran, Michelle M. Nash, Lindita Rapi, Michael Huang and Jeffrey S. Zaltzman

    Citation: BMC Infectious Diseases 2019 19:311

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  28. Content type: Research article

    Early diagnosis of acute invasive fungal rhinosinusitis (AIFRS) is vital to improving outcomes in immunocompromised patients. This study evaluated the impact of a systematic protocol with nasal endoscopy and b...

    Authors: Mariana L. C. Silveira, Wilma T. Anselmo-Lima, Francesca M. Faria, Danielle L. C. Queiroz, Rodrigo L. Nogueira, Marcelo G. J. Leite, Ricardo M. Lessa, Belinda P. Simões, Edwin Tamashiro and Fabiana C. P. Valera

    Citation: BMC Infectious Diseases 2019 19:310

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  29. Content type: Case report

    Staphylococcus aureus has emerged as a leading cause of invasive severe diseases with a high rate of morbidity and mortality worldwide. The wide spectrum of clinical manifestations and outcome observed in staphyl...

    Authors: Charles Vidal, Florence Moulin, Xavier Nassif, Louise Galmiche, Delphine Borgel, Alain Charbit, Capucine Picard, Jean-Paul Mira, Olivier Lortholary, Anne Jamet and Julie Toubiana

    Citation: BMC Infectious Diseases 2019 19:302

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  30. Content type: Case report

    Lactococcus garvieae is an unusual cause of infective endocarditis (IE). No current diagnostic and therapeutic guidelines are available to treat IE caused by these organisms. Based on a case report, we provide a ...

    Authors: Alexandre Malek, Alejandro De la Hoz, Sara Isabel Gomez-Villegas, Cima Nowbakht and Cesar A. Arias

    Citation: BMC Infectious Diseases 2019 19:301

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  31. Content type: Case report

    The bacterial genus Bartonella is distributed worldwide and poses a public health risk. Cat-scratch disease caused by B. henselae in Croatia was first described in 1957. It is present throughout the country: a su...

    Authors: Maja Stepanić, Sanja Duvnjak, Irena Reil, Silvio Špičić, Gordan Kompes and Relja Beck

    Citation: BMC Infectious Diseases 2019 19:299

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  32. Content type: Research article

    The Lebanese Society of Infectious Diseases and Clinical Microbiology (LSIDCM) is involved in antimicrobial stewardship. In an attempt at guiding clinicians across Lebanon in regards to the proper use of antim...

    Authors: Nicholas Haddad, Souha S. Kanj, Lyn S. Awad, Dania I. Abdallah and Rima A. Moghnieh

    Citation: BMC Infectious Diseases 2019 19:293

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  33. Content type: Research article

    Streptococcus tigurinus was recently described as a new streptococcal species within the viridans group streptococci (VGS). The objectives of the present work were to analyse the clinical and microbiological char...

    Authors: María Ercibengoa, Miguel Angel Goenaga, Carmen Ardanuy, Immaculada Grau, Cristina García-de-la-Maria, Manuel Almela, Jose María Miro, Enrique Navas, María Carmen Fariñas, Carlos Ruiz de Alegría, Javier de la Torre, Fernando Fernández, Mercedes Marín, Patricia Muñoz, Beatriz Orden, José Antonio Oteo…

    Citation: BMC Infectious Diseases 2019 19:291

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  34. Content type: Research article

    Purulent meningitis (PM) is a serious life-threatening infection of the central nervous system (CNS) by bacteria or fungi and associated with high mortality and high incidence of CNS sequelae in children. Howe...

    Authors: Chengna Zhao, Xi Wang, Chao Zhang, Bing Liu, Hongbo Jing, Lihua Ming, Hua Jiang, Yuling Zheng, Peng Liu, Gang Liu and Yongqiang Jiang

    Citation: BMC Infectious Diseases 2019 19:289

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  35. Content type: Research article

    Enteric fever is one of the common infectious diseases of humans. The objectives of this study were to:1) estimate the prevalence of enteric fever among febrile patients visiting Ambo hospital; 2) comparison o...

    Authors: Tolera Deksissa and Endrias Zewdu Gebremedhin

    Citation: BMC Infectious Diseases 2019 19:288

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  36. Content type: Case report

    Ruxolitinib is a highly potent janus kinase inhibitor that places its users at risk for various bacterial infections and viral reactivation. However new reports are also emerging that suggest greater immunosup...

    Authors: Katya Prakash and Douglas Richman

    Citation: BMC Infectious Diseases 2019 19:287

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  37. Content type: Research article

    Scrub typhus is an acute disease, characterized by symptoms of fever, which occurs due to infection by Orientia tsutsugamushi. In most cases, patients recover from the disease with appropriate treatment, but seri...

    Authors: Hyun Lee Kim, Hye Rim Park, Choon-Mee Kim, Youn Jung Cha, Na Ra Yun and Dong-Min Kim

    Citation: BMC Infectious Diseases 2019 19:283

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  38. Content type: Case report

    Erysipelothrix rhusiopathiae is a zoonotic pathogen that causes erysipeloid and is most frequently associated with exposure to domestic swine. Infection of native and prosthetic joints is a rarely reported manife...

    Authors: Michael Groeschel, Taya Forde, Shannon Turvey, A. Mark Joffe, Catherine Hui, Prenilla Naidu, Fabien Mavrot, Susan Kutz and Ameeta E. Singh

    Citation: BMC Infectious Diseases 2019 19:282

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  39. Content type: Research article

    We assessed the utility of a multi-target, real-time PCR assay for Bordetella pertussis detection and diagnosis in patients with severe respiratory illness (SRI), influenza-like illness (ILI), and asymptomatic co...

    Authors: Fahima Moosa, Mignon du Plessis, Nicole Wolter, Maimuna Carrim, Cheryl Cohen, Claire von Mollendorf, Sibongile Walaza, Stefano Tempia, Halima Dawood, Ebrahim Variava and Anne von Gottberg

    Citation: BMC Infectious Diseases 2019 19:276

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  40. Content type: Research article

    Little is known about the morbidity and mortality of invasive fungal disease (IFD) at a population level. The aim of this study was to determine the incidence, trends and outcomes of IFD in all haematology-onc...

    Authors: Jake C. Valentine, C. Orla Morrissey, Mark A. Tacey, Danny Liew, Sushrut Patil, Anton Y. Peleg and Michelle R. Ananda-Rajah

    Citation: BMC Infectious Diseases 2019 19:274

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  41. Content type: Case report

    Severe leptospirosis is known to cause multi organ dysfunction including cardiac involvement. In the clinical setting with limited resources, high degree of suspicion is needed to diagnose cardiac involvement ...

    Authors: P. G. N. S. Jayathilaka, A. S. V. Mendis, M. H. M. T. S. Perera, H. M. T. Damsiri, A. V. C. Gunaratne and Suneth Buddhika Agampodi

    Citation: BMC Infectious Diseases 2019 19:265

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  42. Content type: Research article

    Campylobacteriosis is a major public health concern. The weather factors that influence spatial and seasonal distributions are not fully understood.

    Authors: Abdelmajid Djennad, Giovanni Lo Iacono, Christophe Sarran, Christopher Lane, Richard Elson, Christoph Höser, Iain R. Lake, Felipe J. Colón-González, Sari Kovats, Jan C. Semenza, Trevor C. Bailey, Anthony Kessel, Lora E. Fleming and Gordon L. Nichols

    Citation: BMC Infectious Diseases 2019 19:255

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  43. Content type: Research article

    Antimicrobial resistance (AMR) is an increasing public health problem worldwide.

    Authors: László Róbert Kolozsvári, József Kónya, John Paget, Francois G. Schellevis, János Sándor, Gergő József Szőllősi, Szilvia Harsányi, Zoltán Jancsó and Imre Rurik

    Citation: BMC Infectious Diseases 2019 19:253

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  44. Content type: Case report

    During fulminant meningococcal septicaemia, meningococci are often observed in the cerebrospinal fluid (CSF) although the patients have frequently no meningeal symptoms. Meningococcal meningitis, by contrast, ...

    Authors: Mehdi Hage-Sleiman, Nicolas Derre, Charlotte Verdet, Gilles Pialoux, Olivier Gaudin, Patricia Senet, Muriel Fartoukh, Mathieu Boissan and Marc Garnier

    Citation: BMC Infectious Diseases 2019 19:252

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  45. Content type: Research article

    Increased resistance to third-generation cephalosporin (3GC) is a serious concern for community-onset Escherichia coli infection because this resistance easily delays effective treatment. This study surveyed the ...

    Authors: Wu-Pu Lin, Yu-Shan Huang, Jann-Tay Wang, Yee-Chun Chen and Shan-Chwen Chang

    Citation: BMC Infectious Diseases 2019 19:245

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  46. Content type: Research article

    Diarrheal disease kills over half a million people each year in sub-Saharan Africa; the majority are children under 5 years. About 58% of diarrhea cases are associated with poor water, sanitation, and hygiene—...

    Authors: Samantha Winter, Millicent Ningoma Dzombo and Francis Barchi

    Citation: BMC Infectious Diseases 2019 19:242

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