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Bacterial and fungal diseases

Section edited by Ivan FN Hung, Jorge Garbino and Kelvin To

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of bacterial and fungal diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section includes studies relating to antibiotic resistance and healthcare-associated infections.

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  1. Content type: Research article

    Candida bloodstream infections carry a significant mortality risk, justifying the importance of adequate antifungal therapy. This study describes trends in antifungal consumption using the Defined Daily Dose (...

    Authors: Tatiana Aporta Marins, Alexandre R. Marra, Michael B. Edmond, Marines Dalla Valle Martino, Paula Kiyomi Onaga Yokota, Ana Carolina Cintra Nunes Mafra and Marcelino Souza Durão Junior

    Citation: BMC Infectious Diseases 2018 18:187

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  2. Content type: Research article

    The ability of Staphylococcus aureus to invade tissues and cause an infectious disease is the result of a multi-factorial process supported by the huge number of virulence factors inherent to this microorganism t...

    Authors: Esther Viedma, Dafne Pérez-Montarelo, Jennifer Villa, Irene Muñoz-Gallego, Nieves Larrosa, Nuria Fernández-Hidalgo, Joan Gavaldà, Benito Almirante and Fernando Chaves

    Citation: BMC Infectious Diseases 2018 18:177

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  3. Content type: Research article

    Despite vancomycin use is a major risk factor for the emergence of vancomycin resistance, it is frequently inappropriately prescribed, especially as empirical treatment. We evaluated the effect of an antimicro...

    Authors: Pyoeng Gyun Choe, Hei Lim Koo, Doran Yoon, Ji Yun Bae, Eunyoung Lee, Joo-Hee Hwang, Kyoung-Ho Song, Wan Beom Park, Ji Hwan Bang, Eu Suk Kim, Hong Bin Kim, Sang Won Park, Myoung-don Oh and Nam Joong Kim

    Citation: BMC Infectious Diseases 2018 18:178

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  4. Content type: Case report

    Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a rare syndrome characterized by “remitting,” “seronegative” (namely rheumatoid factor-negative), and “symmetrical” synovitis with pit...

    Authors: Moe Kyotani, Tsuneaki Kenzaka, Ryo Nishio and Hozuka Akita

    Citation: BMC Infectious Diseases 2018 18:174

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  5. Content type: Research article

    Quantification of human interactions relevant to infectious disease transmission through social contact is central to predict disease dynamics, yet data from low-resource settings remain scarce.

    Authors: O. le Polain de Waroux, S. Cohuet, D. Ndazima, A. J. Kucharski, A. Juan-Giner, S. Flasche, E. Tumwesigye, R. Arinaitwe, J. Mwanga-Amumpaire, Y. Boum II, F. Nackers, F. Checchi, R. F. Grais and W. J. Edmunds

    Citation: BMC Infectious Diseases 2018 18:172

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  6. Content type: Research article

    A two-stage surgical strategy (debridement-negative pressure therapy (NPT) and flap coverage) with prolonged antimicrobial therapy is usually proposed in pressure ulcer-related pelvic osteomyelitis but has not...

    Authors: Johan Andrianasolo, Tristan Ferry, Fabien Boucher, Joseph Chateau, Hristo Shipkov, Fatiha Daoud, Evelyne Braun, Claire Triffault-Fillit, Thomas Perpoint, Frédéric Laurent, Alain-Ali Mojallal, Christian Chidiac and Florent Valour

    Citation: BMC Infectious Diseases 2018 18:166

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  7. Content type: Research article

    The use of probiotics to improve anti-microbial defence, such as for influenza infections, is increasingly recommended. However, no data are available on the effect of probiotics on flu-associated secondary ba...

    Authors: Nouria Belkacem, Raphaëlle Bourdet-Sicard and Muhamed-Kkeir Taha

    Citation: BMC Infectious Diseases 2018 18:167

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  8. Content type: Research article

    Marked increases in fluconazole resistance in Candida tropicalis have been recently reported. In this study, the molecular mechanisms behind fluconazole resistance were investigated.

    Authors: Longyang Jin, Zhuorui Cao, Qi Wang, Yichen Wang, Xiaojuan Wang, Hongbin Chen and Hui Wang

    Citation: BMC Infectious Diseases 2018 18:162

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  9. Content type: Research article

    Conventional local treatment for medullary osteomyelitis (OM) includes insertion of antibiotic-loaded polymethylmethacrylate (PMMA) cement. Nevertheless, PMMA may delivery irregular concentration of antibiotic...

    Authors: Mateus Trinconi Cunha, Maria Aparecida Murça, Stanley Nigro, Giselle Burlamaqui Klautau and Mauro José Costa Salles

    Citation: BMC Infectious Diseases 2018 18:157

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  10. Content type: Research article

    Posaconazole therapeutic drug monitoring (TDM) is increasingly used in clinical practice. However, the utility of posaconazole TDM and the target of posaconazole plasma concentration for clinical successful pr...

    Authors: Lu Chen, Yan Wang, Tao Zhang, Ying Li, Ti Meng, Leichao Liu, Ruifang Hao and Yalin Dong

    Citation: BMC Infectious Diseases 2018 18:155

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  11. Content type: Research article

    Implant-related infections, including those of peri-prosthetic joint (PJIs), osteosynthesis and other biomaterials, are biofilm-related. Pathogen identification is considered the diagnostic benchmark; however,...

    Authors: Carlo L. Romanò, Maria Teresa Trentinaglia, Elena De Vecchi, Nicola Logoluso, David A. George, Ilaria Morelli and Lorenzo Drago

    Citation: BMC Infectious Diseases 2018 18:154

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  12. Content type: Case report

    Invasive Meningococcal Disease (IMD) is a rare and critical disease in Japan. Most of these cases are caused by capsulated Neisseria meningitidis strains. Non-capsulated (non-typable) strains are considered relat...

    Authors: Shun Kurose, Kyoko Onozawa, Hiroshi Yoshikawa, Kenichiro Yaita, Hideyuki Takahashi, Nobuyuki Shimono and Yoji Nagasaki

    Citation: BMC Infectious Diseases 2018 18:146

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  13. Content type: Research article

    A significant increase in pertussis incidence occurred in Brazil, from 2011 to 2014, despite high coverage of childhood immunization with whole-cell-pertussis (wP) containing vaccines. This study presents pert...

    Authors: Eder Gatti Fernandes, Ana Marli Christovam Sartori, Patrícia Coelho de Soárez, Telma Regina M. P. Carvalhanas, Marcela Rodrigues and Hillegonda Maria Dutilh Novaes

    Citation: BMC Infectious Diseases 2018 18:126

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  14. Content type: Research article

    Corynebacterium diphtheriae is a re-emerging pathogen in Europe causing invasive infections in vaccinated persons and classical diphtheria in unvaccinated persons. In the presented study we analysed genetic chang...

    Authors: Urszula Czajka, Aldona Wiatrzyk, Ewa Mosiej, Kamila Formińska and Aleksandra A. Zasada

    Citation: BMC Infectious Diseases 2018 18:121

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  15. Content type: Research article

    Various studies have identified numerous factors associated with poor clinical outcomes in patients with Staphylococcus aureus bacteraemia (SAB). A new study was created to provide deeper insight into in-hospital...

    Authors: Natasha E. Holmes, J. Owen Robinson, Sebastiaan J. van Hal, Wendy J. Munckhof, Eugene Athan, Tony M. Korman, Allen C. Cheng, John D. Turnidge, Paul D. R. Johnson and Benjamin P. Howden

    Citation: BMC Infectious Diseases 2018 18:107

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  16. Content type: Case report

    Concurrent presence of dengue hemorrhagic fever (DHF), tropical pyomyositis and septicemia due to methicillin-resistant Staphylococcus aureus (MRSA) in a previously healthy person has never been reported. These t...

    Authors: N. D. B. Ehelepola, R. K. G. M. Rajapaksha, D. M. U. B. Dhanapala, T. D. K. Thennekoon and S. Ponnamperuma

    Citation: BMC Infectious Diseases 2018 18:99

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  17. Content type: Research article

    Fluoroquinolones (FQ) are increasingly prescribed for children, despite being labeled for only a limited number of labeled pediatric indications. In this multicenter retrospective drug utilization study, we an...

    Authors: Kevin Meesters, Reiner Mauel, Evelyn Dhont, Johan Vande Walle and Pauline De Bruyne

    Citation: BMC Infectious Diseases 2018 18:89

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  18. Content type: Research article

    Right-sided infective endocarditis (RSIE) is an uncommon diagnosis accounting for less than 10% of cases of infective endocarditis. Optimal management for severely ill patients with RSIE remains challenging be...

    Authors: Hugues Georges, Olivier Leroy, Norair Airapetian, Nicolas Lamblin, Elie Zogheib, Patrick Devos and Sebastien Preau

    Citation: BMC Infectious Diseases 2018 18:85

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