Bacterial and fungal diseases

Section edited by Ivan FN Hung, Jorge Garbino and Kelvin To

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of bacterial and fungal diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section includes studies relating to antibiotic resistance and healthcare-associated infections.

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  1. Research article

    Shifting trends in bacteriology and antimicrobial resistance among gastrointestinal fistula patients in China: an eight-year review in a tertiary-care hospital

    The purpose of this study was to determine the shifting trends in bacteriology and antimicrobial resistance of infectious specimens isolated from gastrointestinal (GI) fistula patients over eight years in China.

    Qinjie Liu, Jianan Ren, Xiuwen Wu, Gefei Wang, Zhiwei Wang, Jie Wu, Jinjian Huang, Tianyu Lu and Jieshou Li

    BMC Infectious Diseases 2017 17:637

    Published on: 21 September 2017

  2. Research article

    Clostridium difficile infection in the Lao People’s Democratic Republic: first isolation and review of the literature

    Current knowledge of the epidemiology of Clostridium difficile infection in Asia, and in particular the Greater Mekong Subregion, is very limited. Only a few studies from Thailand and Vietnam have been reported f...

    Elaine Cheong, Tamalee Roberts, Sayaphet Rattanavong, Thomas V. Riley, Paul N. Newton and David A. B. Dance

    BMC Infectious Diseases 2017 17:635

    Published on: 21 September 2017

  3. Technical advance

    Detection of bacterial pathogens from clinical specimens using conventional microbial culture and 16S metagenomics: a comparative study

    Infectious disease is the leading cause of death worldwide, and diagnosis of polymicrobial and fungal infections is increasingly challenging in the clinical setting. Conventionally, molecular detection is stil...

    Lalanika M. Abayasekara, Jennifer Perera, Vishvanath Chandrasekharan, Vaz S. Gnanam, Nisala A. Udunuwara, Dileepa S. Liyanage, Nuwani E. Bulathsinhala, Subhashanie Adikary, Janith V. S. Aluthmuhandiram, Chrishanthi S. Thanaseelan, D. Portia Tharmakulasingam, Tharaga Karunakaran and Janahan Ilango

    BMC Infectious Diseases 2017 17:631

    Published on: 19 September 2017

  4. Research article

    Antimicrobial resistance in Africa: a systematic review

    Antimicrobial resistance (AMR) is widely acknowledged as a global problem, yet in many parts of the world its magnitude is still not well understood. This review, using a public health focused approach, aimed ...

    Birkneh Tilahun Tadesse, Elizabeth A. Ashley, Stefano Ongarello, Joshua Havumaki, Miranga Wijegoonewardena, Iveth J. González and Sabine Dittrich

    BMC Infectious Diseases 2017 17:616

    Published on: 11 September 2017

  5. Research article

    Antimicrobial resistance in bacterial pathogens among hospitalized children with community acquired lower respiratory tract infections in Dongguan, China (2011–2016)

    Bacterial pathogens are a major cause of childhood community acquired lower respiratory tract infections (CA-LRTIs), and few data described the impact of antimicrobial resistance on children with CA-LRTIs. Thi...

    Xiaoguang He, Mingyu Xie, Siping Li, Junqin Ye, Qi Peng, Qiang Ma, Xiaomei Lu and Baimao Zhong

    BMC Infectious Diseases 2017 17:614

    Published on: 11 September 2017

  6. Research article

    Children with respiratory tract infections in Swedish primary care; prevalence of antibiotic resistance in common respiratory tract pathogens and relation to antibiotic consumption

    The majority of antibiotics consumed in developed countries are prescribed in primary care. However, little is known about resistance levels in the primary care population.

    Mia Tyrstrup, Eva Melander, Katarina Hedin, Anders Beckman and Sigvard Mölstad

    BMC Infectious Diseases 2017 17:603

    Published on: 4 September 2017

  7. Research article

    Acquisition and clearance of multidrug resistant Acinetobacter baumannii on healthy young adults concurrently burned in a dust explosion in Taiwan: the implication for antimicrobial stewardship

    Information is limited about the effect of restricted carbapenem use on clearance of multi-drug resistant Acinetobacter baumannii (MDRAB). We sought to determine the time effect of antibiotic exposure on multi-dr...

    Po-Yen Huang, Shian-Sen Shie, Jung-Jr Ye, Shih-Pin Lin, Tsui-Ping Liu, Ting-Shu Wu, Tsu-Lan Wu, Shiow-Shuh Chuang, Ming-Huei Cheng, Yu-Chia Hsieh and Ching-Tai Huang

    BMC Infectious Diseases 2017 17:598

    Published on: 30 August 2017

  8. Research article

    Spatiotemporal epidemiology of scarlet fever in Jiangsu Province, China, 2005–2015

    A marked increase in the incidence rate of scarlet fever imposed a considerable burden on the health of children aged 5 to 15 years. The main purpose of this study was to depict the spatiotemporal epidemiologi...

    Qi Zhang, Wendong Liu, Wang Ma, Yingying Shi, Ying Wu, Yuan Li, Shuyi Liang, Yefei Zhu and Minghao Zhou

    BMC Infectious Diseases 2017 17:596

    Published on: 30 August 2017

  9. Research article

    The associations between socioeconomic status and risk of Staphylococcus aureus bacteremia and subsequent endocarditis – a Danish nationwide cohort study

    Staphylococcus aureus bacteremia (SAB) is the leading cause of infective endocarditis in several countries. Since socioeconomic status (SES) is known to influence the risk of infectiou...

    Louise Bruun Oestergaard, Michelle D. Schmiegelow, Niels Eske Bruun, Robert L. Skov, Andreas Petersen, Paal Skytt Andersen and Christian Torp-Pedersen

    BMC Infectious Diseases 2017 17:589

    Published on: 25 August 2017

  10. Research article

    Accuracy of different diagnostic tests for early, delayed and late prosthetic joint infection

    A combination of laboratory, histopathological and microbiological tests for diagnosis of prosthetic joint infection (PJI) have been strongly recommended. This study aims to characterize the accuracy of indivi...

    M. Fernández-Sampedro, C. Fariñas-Alvarez, C. Garces-Zarzalejo, M. A. Alonso-Aguirre, C. Salas-Venero, L. Martínez-Martínez and M. C. Fariñas

    BMC Infectious Diseases 2017 17:592

    Published on: 25 August 2017

  11. Case report

    Spondylodiscitis due to Parvimonas micra diagnosed by the melting temperature mapping method: a case report

    It has been suggested that more than 100 bacterial species can be identified using only seven universal bacterial primer sets in the melting temperature (Tm) mapping method and that these findings can be obtai...

    Yoshitsugu Higashi, Shigeki Nakamura, Hideki Niimi, Tomohiro Ueno, Kaoru Matsumoto, Koyomi Kawago, Ippei Sakamaki, Isao Kitajima and Yoshihiro Yamamoto

    BMC Infectious Diseases 2017 17:584

    Published on: 23 August 2017

  12. Case report

    First report of Sneathia sanguinegens together with Mycoplasma hominis in postpartum prosthetic valve infective endocarditis: a case report

    The presence of more than one bacterial agent is relatively rare in infective endocarditis, although more common in prosthetic cases. Molecular diagnosis from a removed heart tissue is considered a quick and e...

    Iva Kotaskova, Petr Nemec, Martina Vanerkova, Barbora Malisova, Renata Tejkalova, Marek Orban, Vita Zampachova and Tomas Freiberger

    BMC Infectious Diseases 2017 17:563

    Published on: 14 August 2017

  13. Research article

    CXCL9, a promising biomarker in the diagnosis of chronic Q fever

    In the aftermath of the largest Q fever outbreak in the world, diagnosing the potentially lethal complication chronic Q fever remains challenging. PCR, Coxiella burnetii IgG phase I antibodies, CRP and 18F–FDG-PE...

    Anne F. M. Jansen, Teske Schoffelen, Julien Textoris, Jean-Louis Mege, Marrigje Nabuurs-Franssen, Ruud P. H. Raijmakers, Mihai G. Netea, Leo A. B. Joosten, Chantal P. Bleeker-Rovers and Marcel van Deuren

    BMC Infectious Diseases 2017 17:556

    Published on: 9 August 2017

  14. Research article

    Diagnostic value of Pentraxin-3 in patients with sepsis and septic shock in accordance with latest sepsis-3 definitions

    Pentraxin-3 (PTX-3) is an acute-phase protein involved in inflammatory and infectious processes. This study assesses its diagnostic and prognostic value in patients with sepsis or septic shock in a medical int...

    Sonja Hamed, Michael Behnes, Dominic Pauly, Dominic Lepiorz, Max Barre, Tobias Becher, Siegfried Lang, Ibrahim Akin, Martin Borggrefe, Thomas Bertsch and Ursula Hoffmann

    BMC Infectious Diseases 2017 17:554

    Published on: 9 August 2017

  15. Database

    An extensible framework and database of infectious disease for biosurveillance

    Biosurveillance, a relatively young field, has recently increased in importance because of increasing emphasis on global health. Databases and tools describing particular subsets of disease are becoming increa...

    Ashlynn R. Daughton, Reid Priedhorsky, Geoffrey Fairchild, Nicholas Generous, Andrea Hengartner, Esteban Abeyta, Nileena Velappan, Antonietta Lillo, Karen Stark and Alina Deshpande

    BMC Infectious Diseases 2017 17:549

    Published on: 7 August 2017

  16. Research article

    The invasome of Salmonella Dublin as revealed by whole genome sequencing

    Salmonella enterica serovar Dublin is a zoonotic infection that can be transmitted from cattle to humans through consumption of contaminated milk and milk products. Outbreaks of human ...

    Manal Mohammed, Simon Le Hello, Pimlapas Leekitcharoenphon and Rene Hendriksen

    BMC Infectious Diseases 2017 17:544

    Published on: 4 August 2017

  17. Research article

    Evaluation of candidemia in epidemiology and risk factors among cancer patients in a cancer center of China: an 8-year case-control study

    Candidemia is the worldwide life-threaten disease, especially in cancer patients. This study was aimed to identify and evaluate the risk factors of candidemia in cancer patients, which will prompt the improvem...

    Ding Li, Rui Xia, Qing Zhang, Changsen Bai, Zheng Li and Peng Zhang

    BMC Infectious Diseases 2017 17:536

    Published on: 3 August 2017

  18. Research article

    Relationship between day 1 and day 2 Vancomycin area under the curve values and emergence of heterogeneous Vancomycin-intermediate Staphylococcus aureus (hVISA) by Etest® macromethod among patients with MRSA bloodstream infections: a pilot study

    In vitro data suggests that suboptimal initial vancomycin exposure may select for heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) infections. However, no clinical studies have evaluated the re...

    Dmitriy M. Martirosov, Monique R. Bidell, Manjunath P. Pai, Marc H. Scheetz, Susan L. Rosenkranz, Corey Faragon, M. Malik, R. E. Mendes, R. N. Jones, Louise-Anne McNutt and Thomas P. Lodise

    BMC Infectious Diseases 2017 17:534

    Published on: 2 August 2017

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