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Bacterial and fungal diseases

Section edited by Ivan FN Hung, Jorge Garbino and Kelvin To

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of bacterial and fungal diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section includes studies relating to antibiotic resistance and healthcare-associated infections.

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  1. Q fever (Coxiella burnetii infection) has been associated with adverse perinatal outcomes. After investigating the obstetrical importance of Q fever on Reunion island and demonstrating an association between inci...

    Authors: Julien Jaubert, Laura Atiana, Sophie Larrieu, Philippe De Vos, Claudine Somon-Payet, Sylvaine Porcherat, Yoan Mboussou, Florence Naze, Sandrine Picot, Malik Boukerrou, Pierre-Yves Robillard and Patrick Gérardin

    Citation: BMC Infectious Diseases 2020 20:261

    Content type: Research article

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  2. To evaluate nasal carriage, antibiotic susceptibility and molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA), as well as the risk factors of MRSA colonization, in human immunodeficien...

    Authors: Yi-Yu Hsu, David Wu, Chien-Ching Hung, Shie-Shian Huang, Fang-Hsueh Yuan, Ming-Hsun Lee, Ching-Tai Huang, Shian-Sen Shie, Po-Yen Huang, Chien-Chang Yang, Chun-Wen Cheng, Hsieh-Shong Leu, Ting-Shu Wu and Yhu-Chering Huang

    Citation: BMC Infectious Diseases 2020 20:254

    Content type: Research article

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  3. Treatment of resistant Pseudomonas aeruginosa infection continues to be a challenge in Latin American countries (LATAM). We synthesize the literature on the use of appropriate initial antibiotic therapy (AIAT) an...

    Authors: Alfredo Ponce de Leon, Sanjay Merchant, Gowri Raman, Esther Avendano, Jeffrey Chan, Griselda Tepichin Hernandez and Eric Sarpong

    Citation: BMC Infectious Diseases 2020 20:250

    Content type: Research article

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  4. Infections with multidrug-resistant organisms (MDRO) pose a serious threat to patients with dysregulated immunity such as in hemophagocytic lymphohistiocytosis (HLH), but such infections have rarely been compr...

    Authors: Mohammad Rubayet Hasan, Manu Somasundaram Sundaram, Sathyavathi Sundararaju, Kin-Ming Tsui, Mohammed Yousuf Karim, Diane Roscoe, Omar Imam, Mohammad A. Janahi, Eva Thomas, Simon Dobson, Rusung Tan, Patrick Tang and Andres Perez Lopez

    Citation: BMC Infectious Diseases 2020 20:237

    Content type: Case report

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  5. Melioidosis-associated peri-prosthetic infection is extremely rare. To date, melioidosis associated septic arthritis of the ankle joint following a medial malleolar internal fixation has not been reported.

    Authors: Umesh Jayarajah, Arulprashanth Arulanantham, Vimaleswaran Koculen, Chamikara Palkumbura, Aadil Faleel and Rukshan Sooriyarachchi

    Citation: BMC Infectious Diseases 2020 20:236

    Content type: Case report

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  7. The most common infection in patients positive for anti-interferon-gamma autoantibodies (anti-IFN-γ AAbs) is disseminated nontuberculous mycobacterial (dNTM) infection. Here, we report a rare case of triple in...

    Authors: Pongprueth Rujirachun, Jirath Sangwongwanich and Methee Chayakulkeeree

    Citation: BMC Infectious Diseases 2020 20:232

    Content type: Case report

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  8. The spectrum of yeasts and their antifungal susceptibility profile are poorly known and treatment of fungal disease has remained empirical. The aim of this study is to determine the spectrum and antifungal sus...

    Authors: Elias Seyoum, Adane Bitew and Amete Mihret

    Citation: BMC Infectious Diseases 2020 20:231

    Content type: Research article

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  9. Vancomycin-resistant enterococcus (VRE) is an important cause of infection in immunocompromised populations. Few studies have described the characteristics of vanB VRE infection. We sought to describe the epidemi...

    Authors: Ouli Xie, Monica A. Slavin, Benjamin W. Teh, Ashish Bajel, Abby P. Douglas and Leon J. Worth

    Citation: BMC Infectious Diseases 2020 20:228

    Content type: Research article

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  10. Rapid control of cholera outbreaks is a significant challenge in overpopulated urban areas. During late-2017, Kinshasa, the capital of the Democratic Republic of the Congo, experienced a cholera outbreak that ...

    Authors: Didier Bompangue, Sandra Moore, Nadège Taty, Benido Impouma, Bertrand Sudre, Richard Manda, Thierno Balde, Franck Mboussou and Thierry Vandevelde

    Citation: BMC Infectious Diseases 2020 20:226

    Content type: Research article

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  11. Otitis media is inflammation of the middle ear, comprising a spectrum of diseases. It is the commonest episode of infection in children, which often occurs after an acute upper respiratory tract infection. Oti...

    Authors: Tewodros Tesfa, Habtamu Mitiku, Mekonnen Sisay, Fitsum Weldegebreal, Zerihun Ataro, Birhanu Motbaynor, Dadi Marami and Zelalem Teklemariam

    Citation: BMC Infectious Diseases 2020 20:225

    Content type: Research article

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  12. Streptococcus suis is a zoonotic pathogen that causes serious systemic infections in pigs and occupation-related infections in humans who contact with pigs or pork products. In China, it has caused two outbreaks ...

    Authors: Fei Jiang, Jingjing Guo, Chen Cheng and Bing Gu

    Citation: BMC Infectious Diseases 2020 20:223

    Content type: Case report

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  13. This study represents the first Scottish retrospective analysis of the microbiology of diabetic foot infections (DFIs). The aims were to compare the microbiological profile of DFIs treated at a Scottish tertia...

    Authors: Katherine E. Macdonald, Crispin Y. Jordan, Emma Crichton, Judith E. Barnes, Gillian E. Harkin, Lesley M. L. Hall and Joshua D. Jones

    Citation: BMC Infectious Diseases 2020 20:218

    Content type: Research article

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  14. Tick-borne lymphadenopathy (TIBOLA) is an infectious disease, mainly caused by species from the spotted fever group rickettsiae and is characterized by enlarged lymph nodes following a tick bite. Among cases o...

    Authors: Jun-Won Seo, Choon-Mee Kim, Na Ra Yun, Dong-Min Kim, Sung Soon Kim, Sangho Choi and Hyuk Chu

    Citation: BMC Infectious Diseases 2020 20:216

    Content type: Case report

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  15. Pulmonary endarteritis is a rare clinical phenomenon with congenital heart that can potentially lead to major complications.

    Authors: Arezoo Khosravi, Zohreh Rostami, Mohammad Javanbakht, Nematollah Jonaidi Jafari, Mohsen Sadeghi Ghahroudi, Mohammad Hassan Kalantar-Motamed, Ramezan Jafari and Behzad Einollahi

    Citation: BMC Infectious Diseases 2020 20:212

    Content type: Case report

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  16. Cellulitis, a frequent cause of admission of adult patients to medical wards, occasionally evolves to sepsis. In this study we analyze the factors related to sepsis development.

    Authors: J. Collazos, B. de la Fuente, J. de la Fuente, A. García, H. Gómez, C. Menéndez, H. Enríquez, P. Sánchez, M. Alonso, I. López-Cruz, M. Martín-Regidor, A. Martínez-Alonso, J. Guerra, A. Artero, M. Blanes and V. Asensi

    Citation: BMC Infectious Diseases 2020 20:211

    Content type: Research article

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  19. Campylobacter jejuni is a motile, gram-negative rod known for causing self-limiting enterocolitis while rarely causing extraintestinal infections. We report the first case of a patient with Campylobacter jejuni o...

    Authors: Joost Hartman, Matthijs Westerman and Jiri F. P. Wagenaar

    Citation: BMC Infectious Diseases 2020 20:199

    Content type: Case report

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  20. Microbial infection is the main cause of increased morbidity and mortality in burn patients, especially infections caused by multiple drug-resistant organisms (MDRO). The purpose of this study was to explore m...

    Authors: Yin-Yin Chen, Ping-Feng Wu, Chii-Shya Chen, Ian-Horng Chen, Wan-Tsuei Huang and Fu-Der Wang

    Citation: BMC Infectious Diseases 2020 20:193

    Content type: Research article

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  21. Human psittacosis, caused by Chlamydia (C.) psittaci, is likely underdiagnosed and underreported, since tests for C. psittaci are often not included in routine microbiological diagnostics. Source tracing traditio...

    Authors: Lenny Hogerwerf, Inge Roof, Marianne J. K. de Jong, Frederika Dijkstra and Wim van der Hoek

    Citation: BMC Infectious Diseases 2020 20:192

    Content type: Research article

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  22. The presentation of clinical leptospirosis has been historically associated with animal workers, slaughterhouse workers and medical veterinarians. This association has shifted to be related to flooding events ...

    Authors: J. García-Méndez, E. Cervera-Ceballos, D. Atilano-López, S. Arroyo-Escalante, D. Moncada-Barrón, M. Leyva-Leyva, R. Hernández-Castro and E. M. Carrillo-Casas

    Citation: BMC Infectious Diseases 2020 20:186

    Content type: Case report

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  23. Staphylococcus aureus (S. aureus) arthritis is one of the most detrimental joint diseases known and leads to severe joint destruction within days. We hypothesized that the provision of auxiliary immunoregulation ...

    Authors: Berglind Bergmann, Ying Fei, Pernilla Jirholt, Zhicheng Hu, Maria Bergquist, Abukar Ali, Catharina Lindholm, Olov Ekwall, Guillaume Churlaud, David Klatzmann, Tao Jin and Inger Gjertsson

    Citation: BMC Infectious Diseases 2020 20:185

    Content type: Research article

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  25. The burden of leptospirosis in Indonesia is poorly understood. Data from an observational study conducted from 2013 to 2016 in seven cities across Indonesia was used to estimate the incidence of leptospirosis ...

    Authors: Muhammad Hussein Gasem, Usman Hadi, Bachti Alisjahbana, Emiliana Tjitra, M. M. D. E. A. H. Hapsari, Endang Sri Lestari, Abu Tholib Aman, Dewi Lokida, Gustiani Salim, Herman Kosasih, Ketut Tuti Parwati Merati, Kanti Laras, Mansyur Arif, Nurhayati Lukman, Pratiwi Sudarmono, Vivi Lisdawati…

    Citation: BMC Infectious Diseases 2020 20:179

    Content type: Research article

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  27. Trichophyton benhamiae is a zoophilic dermatophyte that can cause tinea in humans and animals. Lesions caused by T. benhamiae tend to be highly inflammatory, and patients are often infected by animals or other pa...

    Authors: Jingwen Tan, Xiaoping Liu, Zhiqin Gao, Hong Yang, Lianjuan Yang and Hai Wen

    Citation: BMC Infectious Diseases 2020 20:171

    Content type: Case report

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  28. Infectious meningitis is a serious disease and patient outcome relies on fast and reliable diagnostics. A syndromic panel testing approach like the FilmArray ME can accelerate diagnosis and therefore decrease ...

    Authors: Susanne Pfefferle, Martin Christner, Martin Aepfelbacher, Marc Lütgehetmann and Holger Rohde

    Citation: BMC Infectious Diseases 2020 20:170

    Content type: Research article

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  30. Even though enterococci can cause serious infections in multiple sites, they are a rare cause of pneumonia. We reported a uremic patient with vancomycin-resistant E. faecium (VRE-fm) pneumonia, possibly related t...

    Authors: Fengqin Li, Yonglan Wang, Linlin Sun and Xiaoxia Wang

    Citation: BMC Infectious Diseases 2020 20:167

    Content type: Case report

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  31. Fever is a cause for concern for both parents and the treating pediatrician and a common reason for antibiotic overuse. However, the proportion of children hospitalized for fever with serious bacterial infecti...

    Authors: Ashish Pathak, Radika Upadhayay, Aditya Mathur, Sunil Rathi and Cecilia Stålsby Lundborg

    Citation: BMC Infectious Diseases 2020 20:162

    Content type: Research article

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  32. Cancer and sepsis comorbidity is a major public health problem in most parts of the world including Zimbabwe. The microbial aetiologies of sepsis and their antibiograms vary with time and locations. Knowledge ...

    Authors: Frank Chinowaita, Wendy Chaka, Tinashe K. Nyazika, Tendai C. Maboreke, Emmanuel Tizauone, Prichard Mapondera, Inam Chitsike, Andrew Z. Cakana and Rooyen T. Mavenyengwa

    Citation: BMC Infectious Diseases 2020 20:161

    Content type: Research article

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  33. S. aureus (SA) infective endocarditis (IE) has a very high mortality, attributed to the age and comorbidities of patients, inadequate or delayed antibiotic treatment, and methicillin resistance, among other cause...

    Authors: Carmen Hidalgo-Tenorio, Juan Gálvez, Francisco Javier Martínez-Marcos, Antonio Plata-Ciezar, Javier De La Torre-Lima, Luis Eduardo López-Cortés, Mariam Noureddine, José M. Reguera, David Vinuesa, Maria Victoria García, Guillermo Ojeda, Rafael Luque, José Manuel Lomas, Jose Antonio Lepe and Arístides de Alarcón

    Citation: BMC Infectious Diseases 2020 20:160

    Content type: Research article

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  34. Sepsis is a life-threatening situation, and it can be rendered more severe by coagulopathy. We here examine a novel plasma biomarker for sepsis-induced coagulopathy.

    Authors: Yishan Wang, Huijuan Wang, Chunfang Zhang, Chao Zhang, Huqin Yang, Ruiyue Gao and Zhaohui Tong

    Citation: BMC Infectious Diseases 2020 20:155

    Content type: Research article

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  35. Brucellosis is a zoonotic disease transmitted to humans through contact with infected animals, animal products or consumption of infected dairy products. Brucella infection during pregnancy is of special interest...

    Authors: Robert Makala, Mtebe V. Majigo, George M. Bwire, Upendo Kibwana, Mariam M. Mirambo and Agricola Joachim

    Citation: BMC Infectious Diseases 2020 20:152

    Content type: Research article

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  36. Early diagnosis of neonatal sepsis is essential to prevent severe complications and avoid unnecessary use of antibiotics. The mortality of neonatal sepsis is over 18%in many countries. This study aimed to deve...

    Authors: Dominicus Husada, Pornthep Chanthavanich, Uraiwan Chotigeat, Piyarat Sunttarattiwong, Chukiat Sirivichayakul, Krisana Pengsaa, Watcharee Chokejindachai and Jaranit Kaewkungwal

    Citation: BMC Infectious Diseases 2020 20:151

    Content type: Research article

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  37. Age is a risk factor for infective endocarditis, and almost half of diagnosed patients are age ≥ 60 years. Large national studies have not evaluated inpatient mortality and surgical valvular interventions betw...

    Authors: Ché Matthew Harris, Waseem Khaliq, Aiham Albaeni and Keith C. Norris

    Citation: BMC Infectious Diseases 2020 20:146

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Infectious Diseases 2020 20:243

  38. Pyogenic liver abscess (PLA) is an inflammatory disease with increasing incidence. When it occurs with diabetes mellitus (DM), the risk of recurrence and mortality may increase. However, the effect of DM on th...

    Authors: Zhaoqing Du, Xingchen Zhou, Junzhou Zhao, Jianbin Bi, Yifan Ren, Jia Zhang, Yuxin Lin, Zheng Wu, Yi Lv, Xufeng Zhang and Rongqian Wu

    Citation: BMC Infectious Diseases 2020 20:145

    Content type: Research article

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  39. Obligate anaerobes usually account for less than 10% of bacteria recovered from blood cultures (BC). The relevance of routine use of the anaerobic bottle is under debate. The aim of this study was to evaluate ...

    Authors: M. Lafaurie, E. d’Anglejan, J. L. Donay, D. Glotz, E. Sarfati, M. Mimoun, M. Legrand, E. Oksenhendler, M. Bagot, S. Valade, B. Bercot and J. M. Molina

    Citation: BMC Infectious Diseases 2020 20:142

    Content type: Research article

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  40. Anthrax is an endemic disease that persists in the rural regions of China. The global genetic population structure of B.anthracis has also been defined by the canonical single-nucleotide polymorphisms (canSNP) an...

    Authors: Enmin Zhang, Huijuan Zhang, Jinrong He, Wei Li and Jianchun Wei

    Citation: BMC Infectious Diseases 2020 20:140

    Content type: Research article

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  41. Scrub typhus is an acute febrile illness caused by the obligate intracellular bacterium, Orientia tsutsugamushi. Immunochromatography (ICT) and IgM ELISA are two of the routinely employed antibody based assays fo...

    Authors: Rajendra Gautam, Keshab Parajuli, Tshokey Tshokey, John Stenos and Jeevan Bahadur Sherchand

    Citation: BMC Infectious Diseases 2020 20:138

    Content type: Research article

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  42. Currently, Staphylococcus aureus is one of the most important pathogens worldwide, especially for methicillin-resistant S. aureus (MRSA) infection. However, few reports referred to patients’ MRSA infections in Yu...

    Authors: Feng Liao, Zhishuo Mo, Wenpeng Gu, Wen Xu, Xiaoqing Fu and Yunhui Zhang

    Citation: BMC Infectious Diseases 2020 20:137

    Content type: Research article

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  43. Salmonellosis remains an important public health problem globally. The disease is among the leading causes of morbidity and mortality in developing countries that experience poor hygiene and lack of access to ...

    Authors: Fadhili A. Ngogo, Agricola Joachim, Ahmed M. Abade, Susan F. Rumisha, Mucho M. Mizinduko and Mtebe V. Majigo

    Citation: BMC Infectious Diseases 2020 20:135

    Content type: Research article

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  44. Vertebral osteomyelitis can be attributed to many factors including immunosuppression, diabetes, malignancy, collagen disease, periodontal disease, open fractures, and endoscopic procedures. Anaerobic bacteria...

    Authors: Abhijith Bathini, Christina R. Maxwell, Hirad Hedayat, James Barrett and Zakaria Hakma

    Citation: BMC Infectious Diseases 2020 20:133

    Content type: Case report

    Published on:

  45. Coagulase-negative staphylococci belonging to S. haemolyticus, S. hominis subsp. hominis, S. simulans, and S. warneri are often described as etiological factors of infections. Staphylococci are a phylogenetically...

    Authors: Magdalena Szemraj, Magdalena Grazul, Ewa Balcerczak and Eligia M. Szewczyk

    Citation: BMC Infectious Diseases 2020 20:128

    Content type: Research article

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  46. This study is to elucidate the disinfection effect of ozone producing low-pressure Hg vapor lamps against human pathogens. Ozone producing low-pressure Hg vapor lamps emit mainly 254 nm ultraviolet light C (UV...

    Authors: Wai Szeto, W. C. Yam, Haibao Huang and Dennis Y. C. Leung

    Citation: BMC Infectious Diseases 2020 20:127

    Content type: Research article

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  47. Paracoccidioidomycosis is a neglected tropical disease, endemic in several countries of South America including Colombia. We report a case of a patient with Chronic Multifocal Paracoccidioidomycosis with long-...

    Authors: Deving Arias Ramos, John Alexander Alzate, Ángela María Giraldo Montoya, Yessica Andrea Trujillo and Leidy Yurany Arias Ramos

    Citation: BMC Infectious Diseases 2020 20:119

    Content type: Case report

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  48. Pneumocystis pneumonia (PCP) is increasingly being diagnosed in patients with systemic lupus erythematosus (SLE), and hydroxychloroquine (HCQ) has been found to possess antifungal activities. We hence aimed to...

    Authors: Kai-Jieh Yeo, Hsin-Hua Chen, Yi-Ming Chen, Ching-Heng Lin, Der-Yuan Chen, Chih-Ming Lai and Wen-Cheng Chao

    Citation: BMC Infectious Diseases 2020 20:112

    Content type: Research article

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  49. Urinary tract infection (UTI) is a common cause of morbidity worldwide. Uropathogenic Escherichia coli (UPEC) bacteria are the major cause of urinary tract infections. UPEC strains derive from different phylogene...

    Authors: Belayneh Regasa Dadi, Tamrat Abebe, Lixin Zhang, Adane Mihret, Workeabeba Abebe and Wondwossen Amogne

    Citation: BMC Infectious Diseases 2020 20:108

    Content type: Research article

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  50. Vibrio spp. are aquatic bacteria that are ubiquitous in warm estuarine and marine environments, of which 12 species are currently known to cause infections in humans. So far, only five human infections with V. ha...

    Authors: Thomas Theo Brehm, Laura Berneking, Holger Rohde, Martin Chistner, Carsten Schlickewei, Meike Sena Martins and Stefan Schmiedel

    Citation: BMC Infectious Diseases 2020 20:104

    Content type: Case report

    Published on:

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