Bacterial and fungal diseases

Section edited by Ivan FN Hung, Jorge Garbino and Kelvin To

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of bacterial and fungal diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section includes studies relating to antibiotic resistance and healthcare-associated infections.

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  1. Research article

    Clinical characteristics and outcomes of Pseudomonas aeruginosa bacteremia in febrile neutropenic children and adolescents with the impact of antibiotic resistance: a retrospective study

    Although the proportion of Pseudomonas aeruginosa infections has reduced after the introduction of antibiotics with anti-pseudomonal effects, P. aeruginosa bacteremia still causes high mortality in immunocompromi...

    Hyo Sup Kim, Bo Kyoung Park, Seong koo Kim, Seung Beom Han, Jae Wook Lee, Dong-Gun Lee, Nack-Gyun Chung, Bin Cho, Dae Chul Jeong and Jin Han Kang

    BMC Infectious Diseases 2017 17:500

    Published on: 17 July 2017

  2. Research article

    Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections

    Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We compared clinical disease severity and sought clinical and demographic differences between i...

    A. Frassanito, R. Nenna, A. Nicolai, A. Pierangeli, A. E. Tozzi, P. Stefanelli, R. Carsetti, C. Concato, I. Schiavoni and F. Midulla

    BMC Infectious Diseases 2017 17:492

    Published on: 12 July 2017

  3. Research article

    Bacterial bloodstream infections in a tertiary infectious diseases hospital in Northern Vietnam: aetiology, drug resistance, and treatment outcome

    Bloodstream infections (BSIs) are associated with high morbidity and mortality worldwide. However their aetiology, antimicrobial susceptibilities and associated outcomes differ between developed and developing...

    Vu Quoc Dat, Hieu Ngoc Vu, Hung Nguyen The, Hoa Thi Nguyen, Long Bao Hoang, Dung Vu Tien Viet, Chi Linh Bui, Kinh Van Nguyen, Trung Vu Nguyen, Dao Tuyet Trinh, Alessandro Torre, H. Rogier van Doorn, Behzad Nadjm and Heiman F.L. Wertheim

    BMC Infectious Diseases 2017 17:493

    Published on: 12 July 2017

  4. Research article

    Pharmacoeconomic analysis of antifungal therapy for primary treatment of invasive candidiasis caused by Candida albicans and non-albicans Candida species

    Cost-effectiveness studies of echinocandins for the treatment of invasive candidiasis, including candidemia, are rare in Asia. No study has determined whether echinocandins are cost-effective for both Candida alb...

    Huang-Tz Ou, Tsung-Ying Lee, Yee-Chun Chen and Claudie Charbonneau

    BMC Infectious Diseases 2017 17:481

    Published on: 10 July 2017

  5. Case report

    Pseudonocardia carboxydivorans in human cerebrospinal fluid: a case report in a patient with traumatic brain injury

    Members of the genus Pseudonocardia have been widely reported and recovered from several ecosystems, such as soil samples and plant samples. Pseudonocardia bacteria colonize the microbial communities on the integ...

    Amalia Navarro-Martínez, Noelia Corominas, Caridad Sainz de Baranda, Ángel Escudero-Jiménez, Jorge Galán- Ros, Juan Antonio Sáez- Nieto and Javier Solera

    BMC Infectious Diseases 2017 17:472

    Published on: 6 July 2017

  6. Research article

    Role of outpatient parenteral antibiotic therapy in the treatment of community acquired skin and soft tissue infections in Singapore

    Treatment of community acquired skin and soft tissue infections (SSTIs) is a common indication for outpatient parenteral antibiotic therapy (OPAT) in USA, UK and Australasia, however data from Asia are lacking...

    Monica Chan, Chee Kheong Ooi, Joshua Wong, Lihua Zhong and David Lye

    BMC Infectious Diseases 2017 17:474

    Published on: 6 July 2017

  7. Research article

    Epidemiology of pharyngitis as reported by Zambian school children and their families: implications for demand-side interventions to prevent rheumatic heart disease

    Prompt and appropriate treatment of streptococcal pharyngitis decreases the risk of acute rheumatic fever and rheumatic heart disease (RHD). Understanding public perceptions and behaviors related to sore throa...

    John Musuku, Joyce C. Lungu, Elizabeth Machila, Catherine Jones, Laurence Colin, Sherri Schwaninger, Patrick Musonda, Brigitta Tadmor, Jonathan M. Spector, Mark E. Engel and Liesl J. Zühlke

    BMC Infectious Diseases 2017 17:473

    Published on: 6 July 2017

  8. Case report

    First report of cavitary pneumonia due to community-acquired Acinetobacter pittii, study of virulence and overview of pathogenesis and treatment

    Acinetobacter pittii is a nosocomial pathogen rarely involved in community-acquired infections. We report for the first time that A. pittii can be responsible for cavitary community-ac...

    Romaric Larcher, Alix Pantel, Erik Arnaud, Albert Sotto and Jean-Philippe Lavigne

    BMC Infectious Diseases 2017 17:477

    Published on: 6 July 2017

  9. Research article

    Clinical features and molecular characteristics of childhood community-associated methicillin-resistant Staphylococcus aureus infection in a medical center in northern Taiwan, 2012

    Since first reported in 2002, the rate of methicillin-resistant Staphylococcus aureus (MRSA) among childhood community-associated (CA) S. aureus infection in Taiwan increased significantly up to 2005. There have ...

    Hong-Kai Wang, Chun-Yen Huang and Yhu-Chering Huang

    BMC Infectious Diseases 2017 17:470

    Published on: 5 July 2017

  10. Research article

    Dissemination of Carbapenem-resistant Klebsiella pneumoniae clinical isolates with various combinations of Carbapenemases (KPC-2, NDM-1, NDM-4, and OXA-48) and 16S rRNA Methylases (RmtB and RmtC) in Vietnam

    Twenty-seven clinical isolates of carbapenem-resistant Klebsiella pneumoniae with MICs ≥4 mg/L for imipenem or meropenem were obtained from inpatients in a hospital in Vietnam. Antimicrobial susceptibility tests ...

    Tatsuya Tada, Mitsuhiro Tsuchiya, Kayo Shimada, Tran Thi Thanh Nga, Le Thi Anh Thu, Truong Thien Phu, Norio Ohmagari and Teruo Kirikae

    BMC Infectious Diseases 2017 17:467

    Published on: 4 July 2017

  11. Research article

    Incidence, clinical features, and implications on outcomes of neonatal late-onset sepsis with concurrent infectious focus

    Neonatal bloodstream infection (BSI) is the most important cause of morbidity and mortality in the neonatal intensive care unit (NICU). Although most neonatal BSIs are primary bacteremia, some are associated w...

    I-Hsyuan Wu, Ming-Horng Tsai, Mei-Yin Lai, Lee-Fen Hsu, Ming-Chou Chiang, Reyin Lien, Ren-Huei Fu, Hsuan-Rong Huang, Shih-Ming Chu and Jen-Fu Hsu

    BMC Infectious Diseases 2017 17:465

    Published on: 3 July 2017

  12. Research article

    Cryptococcosis in patients with hematological diseases: a 14-year retrospective clinical analysis in a Chinese tertiary hospital

    Cryptococcal infection has become a public health challenge globally. However, information about cryptococcal infection in patients with hematological diseases remains relatively rare.

    Rui-ying Wang, Yan-qiong Chen, Ji-qin Wu, Xuan Wang, Ya-hui Cao, Hua-zhen Zhao and Li-ping Zhu

    BMC Infectious Diseases 2017 17:463

    Published on: 3 July 2017

  13. Research article

    Effectiveness of ATP bioluminescence assay for presumptive identification of microorganisms in hospital water sources

    Laboratory analysis of organisms in water include arduous methods, such as the multiple tube and membrane filter. The ATP bioluminescence system, proposes a new way of measuring cellular material in water by m...

    Máira Gazzola Arroyo, Adriano Menis Ferreira, Oleci Pereira Frota, Marcelo Alessandro Rigotti, Denise de Andrade, Natalia Seron Brizzotti, Jacqueline Tanury Macruz Peresi, Elza Maria Castilho and Margarete Teresa Gottardo de Almeida

    BMC Infectious Diseases 2017 17:458

    Published on: 30 June 2017

  14. Research article

    The role of Enterococcus spp. and multidrug-resistant bacteria causing pyogenic liver abscesses

    Pyogenic liver abscesses (PLA) remain a significant clinical problem. Unfortunately, little is known about current bacterial susceptibility profiles and the incidence of multidrug resistant organisms (MDROs) c...

    Marcus M. Mücke, Johanna Kessel, Victoria T. Mücke, Katharina Schwarzkopf, Michael Hogardt, Christoph Stephan, Stefan Zeuzem, Volkhard A. J. Kempf and Christian M. Lange

    BMC Infectious Diseases 2017 17:450

    Published on: 26 June 2017

  15. Research article

    Poorer outcomes among cancer patients diagnosed with Clostridium difficile infections in United States community hospitals

    Cancer predisposes patients to Clostridium difficile infection (CDI) due to health care exposures and medications that disrupt the gut microbiota or reduce immune response. Despite this association, the national ...

    Andrew Delgado, Ivan A. Reveles, Felicia T. Cabello and Kelly R. Reveles

    BMC Infectious Diseases 2017 17:448

    Published on: 23 June 2017

  16. Research article

    Socioeconomic status is associated with symptom severity and sickness absence in people with infectious intestinal disease in the UK

    The burden of infectious intestinal disease (IID) in the UK is substantial. Negative consequences including sickness absence are common, but little is known about the social patterning of these outcomes, or th...

    Tanith C. Rose, Natalie L. Adams, Benjamin Barr, Jeremy Hawker, Sarah J. O’Brien, Mara Violato, Margaret Whitehead and David C. Taylor-Robinson

    BMC Infectious Diseases 2017 17:447

    Published on: 23 June 2017

  17. Case report

    Fusobacterial liver abscess: a case report and review of the literature

    Fusobacteriae are facultative anaerobic gram-negative bacilli which cause a range of invasive infections, amongst which pyogenic liver abscesses are rare. We describe a case of Fusobacterium nucleatum liver ab...

    Dilip Jayasimhan, Linus Wu and Paul Huggan

    BMC Infectious Diseases 2017 17:440

    Published on: 20 June 2017

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