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Table 5 Use of cut off values of individual factors and combined score for predicting unfavorable outcome of patients with CM.

From: The clinic-based predictive modeling for prognosis of patients with cryptococcal meningitis

Variable

Cut-off

value

Pvalue

AUC

Sensitivity,

Specificity,

Accuracy,

CSF glucose

≤ 1.71 mmol/L

0.029

0.599

50.0%

76.7%

60.3%

GCS score

≤ 14

<0.001

0.622

26.0%

98.3%

53.8%

Age at onset

>45 yrs

0.018

0.610

70.8%

48.3%

62.2%

ventriculoperitoneal shunt placement

presented

0.003

0.574

19.8%

95.0%

48.7%

Immunocompromised condition

presented

<0.001

0.620

40.6%

83.3%

57.1%

Combined score

>2.67

<0.001

0.815

69.8%

78.3%

73.1%

  1. CM, cryptococcal meningitis; CSF: cerebrospinal fluid; AUC: area under the curve