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Table 4 Cost analysis of each strategy (individual vs. pooled) by country, by assay (MTB/RIF vs. Ultra) to test 1,000 presumptive TB patients

From: Pooling sputum testing to diagnose tuberculosis using xpert MTB/RIF and xpert ultra: a cost-effectiveness analysis

Assay

Country

Testing

Strategy

Proportion positive

Savings

(%)

Cost per test (International $)

Nb of cartridges

Bacteriologically confirmed cases

Cost per bacteriologically confirmed TB case

(International $)

Xpert MTB/RIF

Lao PDR

Individual

12.1%

Reference

40.91

1,000

121

338.07

Pooling

36.7%

37.9%

25.42

617

115

221.04

Nigeria

Individual

14.4%

Reference

31.50

1,000

144

218.77

Pooling

40%

34.6%

20.61

650

136

151.53

Xpert ULTRA

Lao PDR

Individual

11.1%

Reference

40.91

1,000

111

368.53

Pooling

33.3%

41.2%

24.04

583

111

216.56

Nigeria

Individual

12.0%

Reference

31.50

1,000

146

215.77

Pooling

28.8%

45.7%

17.10

538

136

125.77

Brazil

Individual

24%

Reference

25.69

1,000

240

107.06

Pooling

62.6%

12.1%

22.57

876

232

97.30

 

Overall

Individual

  

34.10

  

249.64

Pooling

  

21.95

  

162.44