Table 3 Mean HIV viral loads and mean CD4 + T cell counts according to the prevalence of Integrase Resistance Associated Mutations (INRAMS)
From: Dolutegravir-associated resistance mutations after first-line treatment failure in Brazil
Mutations Profile | Number | Log10 VL | CD4+ |
|---|---|---|---|
Major INRAMS | 7 | 5.01 | 237.71 |
 G118R | 1 | 4.60 | 146.00 |
 E138A | 1 | 4.73 | 29.00 |
 R263K | 4 | 5.16 | 236.25 |
 G140R | 1 | 4.62 | 544.00 |
Minor INRAMS (all) | 18 | 5.17 | 281.07 |
Major plus Minor INRAMs | 5 | 5.15 | 278.06 |
Minor INRAMS (additional) | 13 | 5.22 | 306.30 |
Single Minor INRAM | 15 | 5.22 | 279.92 |
More than 1 Minor INRAM | 3 | 4,77 | 288,5 |
L101I & T124A Pathwayα | |||
 L101I | 46 | 5.17 | 458.16 |
 T124A | 22 | 5.03 | 281.35 |
 Both | 11 | 5.04 | 254.50 |
 Either | 57 | 5.14 | 421.76 |