The impact of multi-drug resistant Pseudomonas aeruginosa infections on acute pancreatitis patients

BMC Infectious Diseases

Table 2 Clinical characteristics and comparison between CRPA and CSPA infections among 23 MDR-PA infected AP patients

Characteristics	CSPA (n = 9)	CRPA (n = 14)	P
Age, years (mean ± SD)	49.1 ± 11.9	53.7 ± 11.1	0.365
Sex, n (%)			0.250
Male	8 (88.9)	8 (57.1)
Female	1 (11.1)	6 (42.9)
Etiology, n (%)			0.512
Hypertriglyceridemia	3 (33.3)	5 (35.7)
Gallstone	5 (55.6)	5 (35.7)
Others	1 (11.1)	4 (28.6)
Classification of AP, n (%)			0.613
Moderately severe AP	5 (55.6)	5 (35.7)
SAP	4 (44.4)	9 (64.3)
Referred patient, n (%)	8 (88.9)	12 (85.7)	0.998
Fungal infection, n (%)	2 (22.2)	8 (57.1)	0.223
MOF, n (%)	0	8 (57.1)	0.018*
Primary site of infections, n (%)			0.265
Lung	4 (44.4)	9 (64.3)
Pancreas (peri)	5 (55.6)	4 (28.6)
Bloodstream	0	1 (7.1)
Prophylactic antibiotics, n (%)			0.019*
Wide-spectrum antibiotics for 3 days	9 (100.0)	7 (50.0)
Carbapenem for 3 days	0	7 (50.0)
Intervention for pancreatic necrosis, n (%)			0.745
Conservative therapy	1 (11.1)	0
Only percutaneous catheter drainage	1 (11.1)	2 (14.3)
Only endoscopic transluminal drainage	1 (11.1)	1 (7.1)
Percutaneous catheter drainage step-up to minimal access retroperitoneal necrosectomy	5 (55.6)	7 (50.0)
Percutaneous catheter drainage step-up to video-assisted retroperitoneal debridement	0	1 (7.1)
Step-up to open necrosectomy	1 (11.1)	3 (21.4)
ICU stays, days (mean ± SD)	12.7 ± 18.1	26.3 ± 21.9	0.120
Hospitalization, days (mean ± SD)	38.6 ± 16.5	54.4 ± 24.3	0.076
Major complications, n (%)
Hemorrhage	0	5 (35.7)	0.116
Intestinal leakage	1 (11.2)	2 (14.3)	1.000
Pancreatic fistula	0	2 (14.3)	0.668
Mortality, n (%)	1 (11.1)	6 (42.9)	0.250

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