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Fig. 4 | BMC Infectious Diseases

Fig. 4

From: Core genome sequencing and genotyping of Leptospira interrogans in clinical samples by target capture sequencing

Fig. 4

Phylogeny of Leptospira genomes and the sequenced samples. The Leptospira sequences from samples were compared using a database of 273 core genomes of pathogenic Leptospira strains (Additional file 1: Table S2) to find the closest homologue. Samples 1–4, 8–17, 19, 20 had a minimal number of single nucleotide polymorphisms (SNPs), deletions, insertions, and multiple nucleotide polymorphisms (MNPs) relative to id246 (L. interrogans sv Copenhageni). Samples 6 and 7 are closely related to id117 (L. kirschneri sv Grippotyphosa) and Sample 5 is closely related to id228 (L. interrogans sv Pyrogenes). The phylogenetic tree was generated using multiple alignment (mafft v7.490) and RaxML software to infer the underlying phylogenetic tree. Visualization was performed via the iTOL web service (https://itol.embl.de)

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