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Table 2 Comparison of demographic and peak biochemical data within a week of admission in survivors and non-survivors enrolled in ICU [mean ± SD or median (Q25 − Q75)].

From: Serum mAST/ALT ratio had high predictive value for adverse outcome of severe fever with thrombocytopenia syndrome with severe condition

parameters

survivors

non-survivors

P-value

N (%)

44 (57.1)

33(42.9)

-

Age (year)

69.6 ± 6.5

71 ± 7.5

0.359

Gender (M/F)

17/27 (38.6/61.4)

18/15(54.5/45.5)

> 0.05

Hospital stay (days)

14.9 ± 12.5

7.5 ± 11.1

< 0.001

ALT (U/L)

120.6 (49.7, 181.3)

125.3 (61.5, 202.6)

> 0.05

AST (U/L)

204.3 (110.5, 494.6)

383.8 (2030.5, 745.5)

> 0.05

AST/ALT ratio

2.57 (1.94, 3.25)

3.83 (2.53, 4.77)

0.001

GGT (U/L)

44.5 (23, 144.3)

55 (26, 176.1)

> 0.05

ALP (U/L)

69.8 (53.3, 188.6)

99.0 (57.4, 158.5)

> 0.05

mAST (U/L)

54.0 (28.9, 120.8)

93.6 (59.1, 159.4)

0.005

mAST/AST ratio

0.25 (0.21, 0.26)

0.25 (0.23, 0.26)

> 0.05

mAST/ALT ratio

0.58 (0.45, 0.78)

0.81 (0.63, 1.15)

< 0.001

cAST (U/L)

153.9 (82.4, 376.2)

292.0 (171.6, 592.7)

0.012

cAST/ALT ratio

1.97 (1.43, 2.47)

3.09 (1.80, 3.57)

0.001

hsTnI (pg/ml)

117.5 (50, 280.6)

261.9 (90.0, 1914.5)

0.007

CK (U/L)

610 (270.5, 1292.8)

925 (474, 2438)

0.033

CK-MB (ng/ml)

6.59 (3.34, 14.42)

6.43 (4.05, 15.02)

> 0.05

α-HBDH (U/L)

527.8 (383.1, 864.2)

1093.9 (614.3, 1068.5)

0.002

LDH (U/L)

855.5 (521.5, 1543.3)

1750 (1095.5, 2792.5)

0.002

  1. ALT: alanine aminotransferase; AST: aspartate aminotransferase; mAST: mitochondrial AST; cAST: cytosolic AST; ALP: alkaline phosphatase; GGT: gamma-glutamyltransferase; hsTnI: high-sensitivity troponin I; CK: creatine kinase; CK-MB: CK heart-type isoenzyme; α-HBDH: α-hydroxybutyrate dehydrogenase; LDH: lactate dehydrogenase