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Table 4 The association of TLR4/TLR9 haplotypes with HR-HPV infection status

From: Association of TLR4 and TLR9 gene polymorphisms with cervical HR-HPV infection status in Chinese Han population

SNPs

Haplotype

Frequencies

P1a

P2b

Overall (%)

Transient infection/Persistent infection (%)

Single infection/multiple infection (%)

TLR4

rs10116253-rs1927911-rs10759931

T-C-A

58.73

56.80/59.94

60.30/56.42

  

C-T-G

39.58

40.27/39.16

37.49/42.66

0.67

0.22

C-T-A

0.75

NA

0.63/0.92

0.12

0.49

T-C-G

0.38

NA

NA

NA

NA

T-T-G

0.19

NA

NA

NA

NA

C-C-G

0.19

NA

NA

NA

NA

T-T-A

0.18

NA

NA

NA

NA

TLR9

rs187084-rs352140

T-C

63.93

70.38/59.93

68.12/57.78

  

C-T

34.00

28.15/37.64

30.62/38.97

0.026

0.048

C-C

1.13

0.49/1.52

0.32/2.32

0.24

0.042

T-T

0.94

0.97/0.92

0.94/0.94

0.46

1

  1. SNP: Single nucleotide polymorphism; TLR4: Toll-like receptor 4; TLR9: Toll-like receptor 9; NA: Not applicable. Bold values are statistically significant
  2. P1: Transient infection VS. Persistent infection; P2: Single infection vs. multiple infections
  3. aAdjusted for age and HR-HPV genotypes
  4. bAdjusted for age