Group | Subgroup | No. of estimates | Sample size (n) | Pooled proportion (%) | 95% CI (%) | Heterogeneity | ||
---|---|---|---|---|---|---|---|---|
I2% (inconsistency) | Cochran Q | P value | ||||||
Low-risk | Children below 20 years with a history of HBV vaccination during infancy | 8 | 5960 | 0.69 | [0.23:1.4] | 76.2 | 29.4 | 0.0001 |
Healthy adults | 12 | 68,494 | 2.4 | [1.28: 3.9] | 74.3 | 42.8 | < 0.0001 | |
Pregnant women | 9 | 5522 | 2.95 | [1.6:4.6] | 89.8 | 78.3 | < 0.0001 | |
blood donors | 15 | 750,515 | 1.8 | [1.4:2.3] | 99.4 | 2235 | < 0.0001 | |
total | 44 | 830,491 | 1.93 | [1.55:2.35] | 99 | 4452.6 | < 0.0001 | |
Intermediate-risk | Health care workers | 7 | 2554 | 1.1 | [0.55:1.8] | 53.9 | 13 | 0.043 |
Other workers | 3 | 2502 | 2.73 | [1.26:4.73] | 83.9 | 12.4 | 0.002 | |
total | 10 | 5056 | ||||||
High-risk | Patients with hemolytic anemia and hemodialysis patients | 10 | 1440 | 6.34 | HBV-infected | 95.8 | 216.3 | < 0.0001 |
direct contact with HBV-infected patients | 1 | 154 | – | – | – | – | – | |
HIV-infected patient | 1 | 141 | – | – | – | – | – | |
total | 12 | 1735 | 5.86 | [1.8:12] | 95.2 | 230.4 | < 0.0001 | |
Liver related conditions | HCC | 2 | 2362 | 18.6 | [4.69:38.9] | 99.2 | 125.6 | < 0.0001 |
HCV | 2 | 308 | 1.57 | [0.49:3.25] | 0 | 0.257 | 0.6117 | |
CLD | 2 | 21,215 | 34 | [8.8:65.59] | 97.5 | 40 | < 0.0001 | |
Total | 23,885 | |||||||
Special cases | Patients with malignancies | 6 | 526 | 25.5 | [14.37:38.6] | 89.5 | 47.6 | < 0.0001 |
Heterogeneous cases | 4 | 345 | 2.27 | [0.95:4.1] | 2.7 | 3.08 | 0.3788 | |
Overall total | 82 | 862,037 | 3.67 | [3:4.39] | 99.5 | 15,617 | < 0.0001 |