Table 6 The association of age, sex, obesity, commodities, and prior COVID-19 infection with local and systemic reactogenicities following the second dose of all vaccines in multiple logistic regression
Adverse effects | Female sex | Age (year) | Commodities | Prior COVID-19 disease | Obesity | |||||
|---|---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
Local | ||||||||||
 Pain | 1.81 (1.55–2.12) | < 0.001 | 0.97 (0.96–0.99) | < 0.001 | 1.20 (1.00–1.45) | 0.048 | 1.43 (1.18–1.73) | < 0.001 | 0.92 (0.73–1.17) | 0.527 |
 Redness | 3.15 (1.77–5.61) | < 0.001 | 0.97 (0.95–0.99) | 0.005 | 1.12 (0.62–2.04) | 0.698 | 1.11 (0.65–1.90) | 0.693 | 1.93 (1.02–3.63) | 0.042 |
 Swelling | 2.79 (1.88–4.14) | < 0.001 | 0.98 (0.97–1.00) | 0.069 | 1.33 (0.86–2.05) | 0.195 | 1.07 (0.72–1.59) | 0.704 | 1.28 (0.77–2.10) | 0.331 |
 Induration | 2.20 (1.53–3.16) | < 0.001 | 0.98 (0.97–0.99) | 0.003 | 1.14 (0.75–1.72) | 0.526 | 0.85 (0.57–1.27) | 0.433 | 1.48 (0.93–2.36) | 0.093 |
 Bruise | 3.22 (1.78–5.82) | < 0.001 | 0.97 (0.96–0.99) | 0.006 | 0.68 (0.39–1.18) | 0.177 | 1.27 (0.75–2.16) | 0.367 | 0.81 (0.36–1.82) | 0.620 |
 Warmness | 3.22 (1.85–5.62) | < 0.00 | 0.98 (0.97–1.00) | 0.101 | 1.06 (0.60–1.87) | 0.818 | 0.76 (0.43–1.36) | 0.365 | 1.14 (0.57–2.27) | 0.706 |
 Itching | 2.58 (1.43–4.65) | 0.002 | 0.98 (0.96–1.00) | 0.094 | 1.00 (0.53–1.86) | 0.994 | 1.32 (0.75–2.31) | 0.322 | 1.26 (0.62–2.68) | 0.494 |
Systemic | ||||||||||
 Fever | 1.56 (1.29–1.90) | < 0.001 | 0.97 (0.97–0.98) | < 0.001 | 1.05 (0.84–1.33) | 0.629 | 1.32 (1.06–1.63) | 0.010 | 1.19 (0.90–1.58) | 0.206 |
 Nausea | 2.83 (2.04–3.91) | < 0.001 | 0.98 (0.97–0.99) | < 0.001 | 0.82 (0.59–1.16) | 0.273 | 1.29 (0.94–1.77) | 0.106 | 0.60 (0.35–1.00) | 0.054 |
 Malaise | 1.74 (1.47–2.07) | < 0.001 | 0.99 (0.98–0.99) | 0.008 | 0.90 (0.73–1.10) | 0.322 | 1.39 (1.14–1.12) | 0.001 | 0.86 (0.66–1.12) | 0.273 |
 Chills | 1.45 (1.15–1.84) | 0.002 | 0.97 (0.96–0.98) | < 0.001 | 1.22 (0.91–1.63) | 0.180 | 1.38 (1.07–1.78) | 0.011 | 1.26 (0.89–1.77) | 0.181 |
 Headache | 1.90 (1.59–2.27) | < 0.001 | 0.98 (0.98–0.99) | < 0.001 | 1.13 (0.91–1.40) | 0.244 | 1.35 (1.10–1.64) | 0.003 | 0.95 (0.73–1.25) | 0.756 |
 Joint pain | 1.54 (1.27–1.88) | < 0.001 | 0.98 (0.97–0.98) | < 0.001 | 0.91 (0.72–1.15) | 0.474 | 1.37 (1.11–1.70) | 0.004 | 0.89 (0.66–1.20) | 0.454 |
 Myalgia | 1.57 (1.32–1.88) | < 0.001 | 0.98 (0.97–0.98) | < 0.001 | 0.92 (0.74–1.13) | 0.445 | 1.30 (1.06–1.59) | 0.010 | 0.95 (0.73–1.25) | 0.742 |
 Fatigue | 1.62 (1.37–1.91) | < 0.001 | 0.99 (0.98–0.99) | 0.001 | 0.88 (0.72–1.07) | 0.226 | 1.25 (1.03–1.51) | 0.020 | 1.03 (0.81–1.31) | 0.785 |