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Table 1 Clinical characteristics and outcomes of 406 children with RV-only detection or RV co-detection in Middle Tennessee

From: Clinical characteristics and outcomes of children with single or co-detected rhinovirus-associated acute respiratory infection in Middle Tennessee

 Clinical characteristics

RV-only detection (n = 289)

RV co-detection (n = 117)

p value*

RV/RSV co-detection (n = 36)

p value*

Age at enrollment in years

     

 Mean (SD)

4.3 (4.4)

2.6 (2.7)

< 0.001

1.1 (1.2)

< 0.001

 Median (IQR)

2.8 (0.8–6.3)

1.5 (0.8–3.4)

 

0.6 (0.2–1.7)

 

Male—n (%)

174 (60.2)

73 (62.4)

0.68

19 (52.8)

0.39

Race and Hispanic origin—n (%)

  

0.63

 

0.042

 Hispanic

70 (24.2)

27 (23.1)

 

7 (19.4)

 

 Non-Hispanic white

87 (30.1)

36 (30.8)

 

14 (38.9)

 

 Non-Hispanic black

115 (39.8)

43 (36.8)

 

9 (25.0)

 

 Non-Hispanic other

17 (5.9)

11 (9.4)

 

6 (16.7)

 

Illness duration at presentation in days

     

 Mean (SD)

3.3 (2.2)

4.1 (2.7)

0.004

4.9 (2.9)

0.001

 Median (IQR)

3 (2–4)

3 (2–6)

 

4.5 (3–7)

 

Breastfeeding historya—n (%)

90/123 (73.2)

45/66 (68.2)

0.47

19/28

0.57

Premature birtha—n (%)

22/121 (18.2)

14/64 (21.9)

0.55

6/26 (23.1)

0.56

Day care or preschool attendanceb—n (%)

52/190 (27.4)

38/94 (40.4)

0.026

12/35 (34.3)

0.40

School attendancec—n (%)

87/94 (92.6)

22/23 (95.7)

0.60

1/1 (100.0)

0.78

Tobacco smoke exposure—n (%)

111 (38.4)

47/116 (40.5)

0.69

17/35 (48.6)

0.25

Gestational tobacco smoke exposurea—n (%)

44/285 (15.4)

15/116 (12.9)

0.52

8/35 (22.9)

0.26

Prior antiviral use—n (%)

1/287 (0.3)

0/116

0.52

0/35

0.73

Prior antibiotic use—n (%)

12/286 (4.2)

16 (13.7)

< 0.001

7/36 (19.4)

< 0.001

Underlying medical condition—n (%)

161 (55.7)

54 (46.2)

0.081

15 (41.7)

0.11

 History of asthma—n (%)

99 (34.3)

15 (12.8)

< 0.001

2 (5.6)

< 0.001

Outcomes

     

 Hospitalized—n (%)

95 (32.9)

28 (23.9)

0.076

16 (44.4)

0.17

 ICU admission—n (%)

9 (9.5)

4 (14.3)

0.47

3 (18.8)

0.27

 Supplemental oxygen use—n (%)

37 (38.9)

16 (57.1)

0.088

10 (62.5)

0.078

 Length of stay—days

     

  Mean (SD)

2.0 (2.6)

2.9 (2.2)

0.097

3.2 (2.5)

0.084

  Median (IQR)

1 (1–2)

2 (1.75–4)

 

2 (1.75–4.25)

 
  1. The most common RV co-detection pair (RV/RSV) is presented separately
  2. Values in bold indicate p < 0.05
  3. aChildren < 2 years old.
  4. bChildren < 5 years old.
  5. cChildren ≥ 5 years old
  6. *p values were calculated using Pearson’s χ2 test for categorical variables and the two-sample t-test with unequal variances for continuous variables
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BMC Infectious Diseases

ISSN: 1471-2334

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