Study population characteristics | Univariate HR | p-value | Multivariate HR | p-value |
---|---|---|---|---|
 | 95% CI |  | 95% CI |  |
Age group, years | Â | Â | Â | Â |
 15–24 | 1.51 (1.47–1.55) |  | 1.85 (1.66–2.07) |  < 0.0001 |
 25–34 | 1.22 (1.20–1.25) |  < 0.0001 | 1.38 (1.28–1.48) | 0.0011 |
 35–44 | Reference |  | Reference |  |
 45–54 | 0.93 (0.91–0.95) |  | 1.03 (0.96–1.11) |  < 0.0001 |
 55 +  | 1.04 (1.02–1.06) |  | 1.20 (1.11–1.32) | 0.1352 |
Sex | Â | Â | Â | Â |
 Female | Reference |  < 0.0001 | Reference |  |
 Male | 0.94 (0.93–0.96) |  | 2.00 (1.51–2.62) |  < .0001 |
District | Â | Â | Â | Â |
 Handeni | 1.18 (1.15–1.20) |  | 0.92 (0.83–1.02) | 0.5184 |
 Kilindi | 1.38 (1.33–1.43) |  | 0.58 (0.48–0.70) |  < 0.0001 |
 Korogwe | 1.29 (1.26–1.32) |  < 0.0001 | 0.85 (0.76–0.94) | 0.00074 |
 Lushoto | 1.11 (1.08–1.14) |  | 1.38 (1.25–1.53) |  < 0.0001 |
 Mkinga | 1.14 (1.02–1.18) |  | 0.41 (0.36–0.46) |  < 0.0001 |
 Muheza | 2.49 (2.44–2.54) |  | 1.22 (1.12–1.33) |  < 0.0001 |
 Pangani | 1.22 (1.18–1.26) |  | 2.13 (1.93–2.35) |  < 0.0001 |
 Tanga | Reference |  | references |  |
Pregnant status | Â | Â | Â | Â |
 No | Reference |  | Reference |  |
 Yes | 1.10 (1.05–1.16) |  < 0.0001 | 0.73 (0.63–0.85) |  < 0.0001 |
Marital status | Â | Â | Â | Â |
 Cohabiting | 0.95 (0.90–1.01) |  | 0.42 (0.35–0.52) |  < 0.0001 |
 Divorced | 1.01 (0.99–1.04) |  < 0.0001 | 1.35 (1.24–1.48) |  < 0.0001 |
 Married | Reference |  | Reference |  |
 Single | 1.31 (1.29–1.34) |  | 1.25 (1.17–1.33) |  < 0.0001 |
 Widow | 1.07 (1.04–1.10) |  | 0.86 (0.76–0.96) | 0.2 |
Viral load suppression | Â | Â | Â | Â |
 Suppressed | Reference |  < 0.0001 | Reference |  < 0.0001 |
 Non-suppressed | 2.30 (2.24–2.37) | 2.15 (2.02–2.29) |  | |
BMI (kg/m2) | Â | Â | Â | Â |
 < 18.5 | 1.95 (1.84–2.07) |  < 0.0001 | 1.75 (1.30–2.34) | 0.0472 |
 18.5–< 25 | Reference | Reference |  | |
 25–30 | 1.57 (1.48–1.67) | 1.46 (1.10–1.95) | 0.5589 | |
 30 +  | 1.60 (1.50–1.68) | 1.34 (0.93–1.93) | 0.9229 | |
WHO clinical stage | Â | Â | Â | Â |
 I | Reference |  < 0.0001 | Reference |  |
 II | 0.01 (0.88–0.92) | 1.67 (1.52–1.84) | 0.1226 | |
 III | 1.08 (1.06–1.09) | 2.51 (2.32–2.72) |  < 0.0001 | |
 IV | 1.18 (1.15–1.21) | 2.24 (2.02–2.49) |  < 0.0001 | |
Drug type | Â | Â | Â | Â |
 First-line | Reference |  < 0.0001 | Reference |  < 0.0001 |
 Second-line | 1.13 (1.09–1.18) | 1.19 (0.84–1.69) |  | |
Adherence | Â | Â | Â | Â |
 Good | Reference |  < 0.0001 | Reference |  |
 Poor | 1.75 (1.69–1.82) | 1.50 (1.23–1.75) |  < 0.0001 | |
ART duration | Â | Â | Â | Â |
 ≤ 1 | 1.10 (1.08–1.12) |  < 0.0001 | 0.72 (0.65–0.81) |  < 0.0001 |
 > 1 | Reference | Reference |  | |
TB history | Â | Â | Â | Â |
 No | Reference |  < 0.0001 | Reference |  |
 Yes | 1.92 (1.79–2.05) | 1.19 (0.84–1.69) | 0.3187 | |
DTG-related drug | Â | Â | Â | Â |
 No | 5.80 (4.98–6.64) |  < 0.0001 | 7.51 (5.88–10.79) |  < 0.0001 |
 Yes | Reference | Reference |  |