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Table 4 Trends in percentage of admissions prescribed antibiotics (95% CI)

From: A multicenter evaluation of antibacterial use in hospitalized patients through the SARS-Cov-2 pandemic waves

Time period

Total

SARS-CoV-2 + 

SARS-CoV-2-

Not tested

Adjusted % positive GN/GP culture

% Prescribed Abx therapy ≥ 24 h

Adjusted % positive GN/GP culture

% Prescribed Abx therapy ≥ 24 h

Adjusted % positive GN/GP culture

% Prescribed Abx therapy ≥ 24 h

Adjusted % positive GN/GP culture

% Prescribed Abx therapy ≥ 24 h

Pre-pandemic: July 2019–Feb 2020

9.49

(8.86–10.13)

36.66

(35.46–37.87)

NA

NA

NA

NA

NA

NA

March 2020–May 2020

9.61

(8.98–10.24)

37.76

(36.97–38.55)

13.34

(12.45–14.23)

68.02

(66.57–69.46)

12.23

(11.32–13.13)

46.99

(45.49–48.49)

8.51

(7.88–9.13)

32.48

(31.15–22.81)

June 2020–August 2020

9.38

(8.75–10.01)

35.50

(34.31–36.69)

12.89

(11.77–14.00)

62.82

(60.55–65.08)

11.08

(10.17–11.99)

40.30

(38.87–41.73)

6.81

(6.17–7.44)

29.44

(28.11–20.78)

Sept 2020–Nov 2020

9.57

(8.95–10.20)

36.89

(35.70–38.08)

11.60

(10.52–12.69)

57.49

(54.27–58.72)

10.99

(10.03–11.94)

40.00

(38.56–41.44)

6.92

(6.29–7.55)

30.90

(29.57–32.24)

Dec 2020–Feb 2021

9.69

(9.06–10.33)

38.43

(37.24–39.62)

11.69

(10.75–12.63)

57.31

(55.11–59.51)

10.88

(9.95–11.80)

39.57

(38.12–41.01)

6.71

(6.08–7.34)

31.67

(30.33–33.01)

March 2021–May 2021

9.17

(8.53–9.81)

36.01

(34.81–37.21)

11.72

(10.76–12.68)

54.10

(51.84–56.36)

10.38

(9.47–11.30)

39.48

(38.02–40.95)

6.50

(5.87–7.14)

30.13

(28.78–31.48)

June 2021–October 2021

9.35

(8.76–9.94)

36.18

(35.05–37.32)

10.99

(9.73–12.25)

53.59

(51.50–55.67)

10.93

(10.07–11.80)

39.38

(38.01–40.74)

6.61

(6.02–7.20)

31.01

(29.73–32.29)

  1. Abx antibiotic, GN Gram-negative, GP Gram-positive