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Table 2 Trends by waves in GN/GP pathogens and antibiotic therapy for pre- and post-SARS-CoV-2 periods by SARS-CoV-2 testing status

From: A multicenter evaluation of antibacterial use in hospitalized patients through the SARS-Cov-2 pandemic waves

Time period

SARS-CoV-2 + 

SARS-CoV-2 −

SARS-CoV-2 not tested

Total admissions

Prescribed antibacterial therapy ≥ 24 h

Positive GN/GP culture during hospital stay

Prescribed antibacterial therapy ≥ 24 h

Positive GN/GP culture during hospital stay

Prescribed antibacterial therapy ≥ 24 h

Positive GN/GP culture during hospital stay

Prescribed antibacterial therapy ≥ 24 h

Positive GN/GP culture during hospital stay

Total: Jul 2019–Oct 2021

57.8%* (109,337/189,115)

11.9%*

(22,558/

189,115)

40.1%

(761,398/

1,898,659)

11.0%*

(208,162/

1,898,659)

32.8% (1,124,606/3,430,970)

8.3%*

(285,279/

3,430,970)

36.2%

(1,995,381/

5,518,744)

9.3%

(515,999/

5,518,744)

Baseline: Jul 2019–Feb 2020

    

35.0% (625,994/1,789,449)

9.3%

(167,045/

1,789,449)

35.0%

(625,994/

1,789,449)

9.3%

(167,045/

1,789,449)

Total: Mar 2020–Oct 2021

57.8% (109,337/189,115)

11.9%

(22,558/

189,115)

40.1%

(761,398/

1,898,659)

11.0%

(208,162/

1,898,659)

30.4%

(498,612/

1,641,521)

7.2%

(118,234/

1,641,521)

36.7%

(1,369,387/

2,359,908)

9.4%

(348,954/

3,729,295)

Mar 2020–May 2020

67.8% (10,643/15,702)

13.2%

(2,067/

15,702)

46.8%

(54,681/

116,755)

12.5%

(14,541/

116,755)

33.3%

(132,120/396,348)

8.7% (34,422/396,348)

37.3% (197,444/528,805)

9.7%

(51,030/

528,805)

Jun 2020–Aug 2020

63.2% (16,862/26,699)

12.9%

(3,443/

26,699)

40.2%

(130,724/

324,814)

11.2%

(36,312/

324,814)

27.9% (73,288/262,947)

6.7% (17,740/262,947)

35.9% (220,874/614,460)

9.4%

(57,495/

614,460)

Sep 2020–Nov 2020

57.6% (15,025/26,081)

11.5%

(2,995/

26,081)

40.0%

(135,412/

338,745)

11.0%

(37,135/

338,745)

30.3% (70,141/231,131)

7.0% (16,225/231,131)

37.0% (220,578/595,957)

9.5%

(56,355/

595,957)

Dec 2020–Feb 2021

57.2% (33,076/57,819)

11.9%

(6,873/

57,819)

39.4%

(126,140/

319,865)

10.7%

(34,346/

319,865)

30.8% (57,306/186,155)

6.6% (12,194/186,155)

38.4% (216,522/563,839)

9.5%

(53,413/

563,839)

Mar 2021–May 2021

54.4% (10,686/19,645)

12.2%

(2,392/

19,645)

39.5%

(139,349/

353,050)

10.6%

(37,445/

353,050)

28.9% (66,789/231,491)

6.6% (15,191/231,491)

35.9% (216,824/604,186)

9.1%

(55,028/

604,186)

Jun 2021–Oct 2021

53.5% (23,085/43,169)

11.1%

(4,788/

43,169)

39.3%

(175,092/

445,430)

10.9%

(48,383/

445,430)

29.7% (98,968/333,449)

6.7% (22,462/333,449)

36.1% (297,145/822,048)

9.2%

(75,633/

822,048)

  1. GN Gram-negative, GP Gram-positive
  2. *P < 0.05 bivariate chi-squared correlation tests