Table 3 Validation of point estimates and 95% confidence intervals from the lateral flow test (LFT) sensitivity obtained from the fitted Binomial mixed model against proportional sensitivity, for each brand at Dose 2
LFT brand | Nucleoprotein and Spike | Model sensitivity [CI95%] | Proportional sensitivity [CI95%] |
|---|---|---|---|
WANTAI SARS-CoV-2 Ab Rapid Test (Beijing Wantai Biological Pharmacy) | Spike-RBD | 76.58 [66.19, 82.18] | 89.86 [80.21, 95.82] |
Onsite COVID-19 IgG/IgM Rapid Test (CTK Biotech) | Spike | 97.03 [92.46, 98.51] | 100 [94.79, 100.00] |
COVID-19 Total Ab Device (Fortress Diagnostics LTd) | Spike-RBD | 99.30 [96.46, 99.73] | 100 [94.79, 100.00] |
NowCheck COVID-19 IgM/IgG Test (Bionote Co., LTD.) | Nucleoprotein | 93.30 [86.68, 96.32] | 100 [94.79, 100.00] |
Edinburgh Genetics COVID-19 Colloidal Gold Immunoassay Testing Kit, IgG/IgM Combined (Edinburgh Genetics) | Nucleoprotein | 89.79 [81.93, 93.24] | 94.2 [85.82, 98.4] |
Diagnostic Kit for SARS-CoV-2 IgM/IgG Antibody (Colloidal Gold) (Shanghai Kehua Bio-Engineering Co., Ltd.) | Nucleoprotein | 20.15 [13.15, 30.02] | 11.59 [5.14, 21.57] |
SARS-CoV-2 IgM/IgG Ab Rapid Test (Qingdao HIGHTOP Biotech Co., Ltd.) | Nucleoprotein and spike | 90.19 [82.70, 93.87] | 95 [87.82, 99.09] |
P4DETECT COVID-19 IgM/IgG (PRIME4DIA Co., Ltd) | Nucleoprotein and spike | 74.95 [66.93, 84.41] | 88.41 [78.43, 94.86] |