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Table 2 Epidemiological and clinical characteristics compared of ESBL and non-ESBL UTI in cancer patients

From: Extended-spectrum beta-lactamase-producing Enterobacteriaceae related urinary tract infection in adult cancer patients: a multicenter retrospective study, 2015–2019

Description

Total (n = 358)

ESBL (n = 160)

n(%)

Non-ESBL (n = 198)

n (%)

P-value

Age, years

58.98 ± 12.32

58.53 ± 13.59

59.35 ± 11.21

0.536

Gender, Male

144 (40.2)

72 (45.0)

72 (36.4)

0.098

Hospital areas

   

0.805

 CAMS

94 (26.3)

42 (26.3)

52 (26.3)

 

 SH

77 (21.5)

32 (20.0)

45 (22.7)

 

 HX

187 (52.2)

86 (53.8)

101 (51.0)

 

Smoking

95 (26.5)

44 (27.5)

51 (25.8)

0.710

Diabetes

74 (20.7)

35 (21.9)

39 (19.7)

0.613

Fever (≥ 37.3℃)

87 (24.3)

44 (27.5)

43 (21.7)

0.205

Chemotherapy within 6 months

234 (65.4)

93 (58.1)

120 (60.6)

0.634

Surgery or invasive manipulation within 6 months

129 (36.0)

69 (43.1)

60 (30.3)

0.012

Radiotherapy within 6 months

77 (21.5)

31 (19.4)

46 (23.2)

0.377

Received antibiotics within 1 week

192 (53.6)

90 (56.3)

102 (51.5)

0.372

Urethral catheterization

194 (54.2)

106 (66.3)

88 (44.4)

 < 0.001

Used glucocorticoids within 2 weeks

161 (45.0)

68 (42.5)

93 (47.0)

0.398

Hematologic analysis

    

 Leukocyte reduced

23 (6.4)

10 (6.3)

13 (6.6)

0.904

 Hemoglobin reduced

173 (48.3)

82 (51.3)

91 (46.0)

0.319

 Serum creatinine increased

10 (2.8)

3 (1.9)

7 (3.5)

0.522

 Plasma albumin reduced

114 (31.8)

52 (32.5)

62 (31.3)

0.811

Routine urinalysisa

    

 Leukocytes increased

245 (71.4)

120 (80.0)

125 (64.8)

0.002

 Protein positive

166 (48.4)

85 (56.7)

81 (42.0)

0.006

 Erythrocytes increased

226 (65.9)

81 (54.0)

145 (75.1)

 < 0.001

 Bacteriuria increased

268 (78.1)

122 (81.3)

146 (75.6)

0.098

  1. ESBL extended-spectrum beta lactamase, UTI urinary tract infection, CAMS Cancer hospital, Chinese academy of medical science, SH Beijing Chaoyang Sanhuan Cancer Hospital, HX Cancer Hospital of Huanxing Chaoyang District Beijing
  2. a343 episodes had the detection results of routine urinalysis, including 150 in ESBL group and 193 in non-ESBL group
  3. Leukocyte reduced < 2.0 × 109/L white blood cells in routine blood test, Hemoglobin reduced < 110 g/L hemoglobin in routine blood test, Serum creatinine increased > 133 umol/L creatinine in serum, Plasma albumin reduced ≤ 35.0 g/L plasma albumin, Leukocytes increased ≥ 10 leukocytes/HP in microscopy by sediment urinalysis, Protein positive ≥ 1 + by Dry Chemistry, Erythrocytes increased ≥ 10 erythrocytes/HP in microscopy by sediment urinalysis, Bacteriuria increased > 340 /uL by formed elements urinalysis