Factors associated with relapse and hospital death in patients coinfected with visceral leishmaniasis and HIV: a longitudinal study

Table 4 Median and interquartile range of serum biomarkers according to visceral leishmaniasis relapse and death by the time of the follow-up

Variables	VL relapse		p value	Death		p value
	Yes	No		Yes	No
	Median [IQR]	Median [IQR]		Median [IQR]	Median [IQR]
Red blood cells (million/mm³)	3.23 [2.76–3.67]	3.19 [2.58–3.65]	.884	2.77 [2.33–3.36]	3.27 [2.73–3.70]	.012
Hemoglobin (g/dl)	8.95 [7.70–10.80]	8.70 [7.40–10.20]	.472	7.90 [6.70–8.70]	8.90 [7.60–10.70]	.017
Hematocrit (%)	26.7 [23.2–32.8]	26.4 [22.6–31.6]	.686	24.3 [20.0–27.8]	26.8 [23.1–32.0]	.054
Leukocytes (1000/mm³)	2.08 [1.44–3.88]	2.30 [1.60–3.73]	.421	2.04 [1.37–4.02]	2.26 [1.55–3.77]	.790
Platelets (1000/mm³)	120.5 [82.0–150.0]	121.0 [87.0–186.0]	.510	52.5 [33.0–81.0]	155.0 [122.0–215.0]	< .001
AST (U/l)	41.0 [28.0–60.0]	41.0 [27.0–59.0]	.640	48.0 [37.0–76.0]	40.0 [27.0–59.0]	.211
ALT (U/l)	28.5 [18.0–63.0]	31.0 [20.0–55.0]	.606	24.0 [17.0–43.0]	29.0 [20.0–46.0]	.331
Urea (mg/dl)	39.5 [27.5–51.5]	32.0 [23.0–40.0]	.005	44.5 [28.0–56.0]	34.0 [25.0–45.0]	.122
Creatinine (mg/dl)	1.02 [.84–1.23]	.76 [.56–0.93]	< .001	1.03 [.69–1.36]	.87 [.67–1.09]	.182

VL visceral leishmaniasis, IQR interquartile range [1st quartile–3rd quartile], AST aspartate aminotransferase, ALT alanine aminotransferase

ISSN: 1471-2334