Table 3 Comparison of the specificity and positive rate of QFT-PLUS and TST
Studies (n) | Participants (n) | QFT-PLUS positive | I2 (%) | TST positive | I2 (%) | RD-test | I2 (%) | |
|---|---|---|---|---|---|---|---|---|
Populations with very low risk of TB exposure | 2 | 151 | 0.782 (0.712–0.844) | 0 | 0.662 (0.585–0.735) | 0 | 0.12 (0.02–0.22) | 0 |
High-risk populations | 10 | 1743 | 0.298 (0.161–0.456) | 98 | 0.327 (0.198–0.471) | 97 | − 0.03 (− 0.16–0.11) | 95 |
Recent contacts | 4 | 794 | 0.339 (0.221–0.468) | 94 | 0.361 (0.224–0.511) | 95 | − 0.03 (− 0.14–0.08) | 73 |
Immunocompromised patients | 1 | 71 | NA | NA | NA | NA | 0.10 (0.00–0.20) | NA |
With possibility of contact | 1 | 158 | NA | NA | NA | NA | 0.01 (− 0.04–0.06) | NA |
With possibility of immunosuppression | 4 | 720 | 0.370 (0.083–0.722) | 99 | 0.472 (0.327–0.620) | 94 | − 0.08 (− 0.43–0.27) | 98 |