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Table 2 Univariate and multivariable level analysis of factors associated with COVID-19 mortality among PLWH

From: The clinical and epidemiological characteristics of a series of patients living with HIV admitted for COVID-19 in a district hospital

Characteristic

RR (95% CI)

p

ARR (95% CI)

p

Age categories

    

  < 40

1

   

 40–49

1.96 (0.94–4.07)

0.072

2.24 (0.76–6.64)

0.143

  ≥ 50

2.88 (1.46–5.67)

0.002

2.32 (0.67–8.14)

0.186

Sex: Female

1.62 (1.04–2.52)

0.032

2.00 (0.85–4.67)

0.111

Smoker

2.86 (1.75–4.69)

 < 0.001

4.17 (1.50–11.61)

0.006

Hypertension

1.32 (0.85–2.05)

0.220

0.93 (0.40–2.19)

0.869

Diabetes Mellitus

1.29 (0.82–2.04)

0.271

1.04 (0.51–2.16)

0.904

Chronic Kidney Disease

1.46 (0.73–2.93)

0.283

  

TB

1.35 (0.76–2.38)

0.309

  

Viral Load: Detectable

1.18 (0.65–2.16)

0.588

  

Congestive Heart Failure

1.87 (0.77–4.52)

0.168

  

Acute kidney injury

2.11 (1.36–3.30)

0.001

0.71 (0.33–1.57)

0.401

ARDS

1.17 (0.43–3.15)

0.760

  

Shock

1.22 (0.37–4.03)

0.742

  

Cough

0.88 (0.54–1.45)

0.624

  

Fever

0.87 (0.55–1.39)

0.565

  

Sore Throat

0.59 (0.23–1.50)

0.265

  

Myalgia

0.868 (0.50–1.52)

0.621

  

ARV therapy

1.04 (0.46–2.36)

0.922

  

*CD4: 200–499

1

   

 < 200

1.58 (0.94–2.65)

0.085

1.27 (0.62–2.61)

0.509

 ≥ 500

0.55 (0.22–1.38)

0.202

0.35 (0.09–1.29)

0.114

pa02

1.012 (0.96–1.07)

0.665

  

HGT

0.999 (0.973–1.03)

0.944

  

CRP

1.003 (1.001–1.005)

 < 0.001

1.002 (1.002–1.01)

0.032

Creatinine

1.001 (1.001–1.002)

 < 0.001

1.00 (0.99–1.00)

0.187

WCC

1.05 (1.01–1.08)

0.005

  

Neutrophils

1.024 (1.01–1.03)

 < 0.001

1.03 (1.02–1.06)

 < 0.001

HbA1c

1.01 (1.007–1.01)

 < 0.001

1.01 (1.001–1.02)

0.011

Platelets

0.999 (0.997–1.00)

0.477

  

Lymphocytes

0.882 (0.58–1.34)

0.557

  
  1. ARDS Acute respiratory distress syndrome, ARV antiretroviral, CD4 cluster of differentiation 4, CRP: C-reactive protein, HbA1c Glycated haemoglobin A1, HGT haemo glucose test, PaO2 partial pressure of oxygen, TB tuberculosis, WCC white cell count
  2. *CD4 counts: At least six months prior to SARS-CoV-2 infection