Group | Sensitivity of the IgM/IgG antibody isotype, % (95% CI) | Sensitivity of the IgM antibody isotype, % (95% CI) | Sensitivity of the IgG antibody isotype, % (95% CI) | IgM vs. IgG isotype, p–value |
---|---|---|---|---|
Full sample (n = 492) | 46.7 (42.4, 51.2) | 36.6 (32.5, 40.9) | 36.4 (32.3, 40.7) | 1.0 |
Presence of reported symptoms | ||||
Yes (n = 372) | 44.6 (39.7, 49.7) | 36.3 (31.6, 41.3) | 34.4 (29.8, 39.4) | 0.65 |
No (n = 120) | 53.3 (44.4, 62.0) | 37.5 (29.4, 46.4) | 42.5 (34.0, 51.4) | 0.51 |
Yes vs. no, p–value | 0.12 | 0.90 | 0.14 | n/a |
Time since onset of earliest symptom, among those reporting symptoms (N = 372) | ||||
Week 1 (n = 224) | 30.4 (24.7, 36.6) | 24.1 (19.0, 30.1) | 18.8 (14.2–24.4) | 0.21 |
Week 2 (n = 106) | 62.3 (52.7, 70.9) | 52.8 (43.4, 62.1) | 53.8 (44.3–63.0) | 1.0 |
Week 3 (n = 31) | 77.4 (59.8, 88.8) | 58.1 (40.7, 73.5) | 74.2 (56.5–86.4) | 0.28 |
Week 4 (n = 6) | 83.3 (41.6, 98.4) | 83.3 (41.6, 98.4) | 50.0 (19.0–81.0) | 0.54 |
Week 5+ (n = 5) | 60.0 (23.1, 88.0) | 40.0 (12.0–76.9) | 60.0 (23.1–88.0) | 1.0 |
Comparing time intervals, p–value | < 0.01 | < 0.01 | < 0.01 | n/a |