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Table 3 Clinical and demographical characteristics of PWH stratified by liver steatosis

From: Circulating levels of endotrophin and cross-linked type III collagen reflect liver fibrosis in people with HIV

 

PWH (all)

PWH without presence of steatosis (CAP < 238 dB/m)

PWH with steatosis (CAP ≥ 238 dB/m)

P-value

Total number of participants n (%)

141 (100)

79 (56.0)

62 (44.0)

N.a

Age (years)

47 (24–72)

47 (24–72)

47 (30–69)

N.s

Sex (male/female)

120/21

65/14

55/7

N.s

BMI (kg/cm2)

24 (19–36)

23 (19–33)

25 (20–36)

0.010

AST (U/L)

23 (9–93)

23 (9–65)

24 (13–93)

N.s

ALT (U/L)

29 (10–110)

29 (10–99)

31 (12–110)

0.015

GGT (U/L)

46 (16–302)

45 (17–301)

51 (16–302)

N.s

Thrombocytes

206 (46–400)

203 (46–400)

212 (78–342)

N.s

Transient elastography (kPa)

4.9 (2.0–49.6)

4.7 (22.0–49.0)

5.3 (3.1–26.3)

N.s

Steatosis CAP dB/m)

232 (100–378)

210 (100–237)

272 (238–378)

N.a

Cholinesterase

13,264 (7168–24,175)

12,501 (7168–22,233)

14,824 (7265–24,175)

N.s

PC3X (ng/ml)

6.7 (1.5–33.3)

6.5 (3.4–33.3)

6.8 (1.5–21.5)

N.s

PRO-C5 (ng/ml)

465 (130.0–998.4)

443.9 (130.0–998.4)

503.0 (130.0–825.4)

0.014

PRO-C6 (ng/ml)

6.9 (3.7–22.6)

6.9 (3.7–22.6)

7.0 (4.6–18.5)

N.s

Anti-HCV-positive (%)

18 (12.8)

11 (13.9)

7 (11.3)

N.s

Hbs-Ag positive (%)

4 (2.8)

1 (1.3)

3 (4.8)

N.s

  1. All values are given as median and range
  2. ALT alanine aminotransferase, AST aspartate aminotransferase, BMI Body-mass index, CAP Controlled attenuation parameter, GGT γ–glutamyl transferase, n.a. not applicable, n.s. not significant
  3. Significant p-values are shown in bold