Age years | Male | Female | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cases | Controls | Cases vs. controls | Cases | Controls | Cases vs. controls | |||||||||||||
N | n | (%) | N | n | (%) | P-value | OR | (95% CI) | N | n | (%) | N | n | (%) | P-value | OR | (95% CI) | |
Obesity | 117 | 66 | (56) | 2701 | 685 | (25) | < 0.001 | 3.81 | (2.62–5.55) | 74 | 32 | (43) | 3158 | 853 | (27) | < 0.001 | 2.06 | (1.29–3.28) |
18–49 | 8 | 5 | (63) | 1108 | 241 | (22) | 0.016 | 6.00 | (1.42–25.27) | 8 | 3 | (38) | 1244 | 256 | (21) | 0.374 | 2.32 | (0.55–9.75) |
50–64 | 18 | 12 | (67) | 833 | 260 | (31) | 0.003 | 4.41 | (1.64–11.87) | 11 | 6 | (55) | 925 | 282 | (30) | 0.103 | 2.74 | (0.83–9.04) |
65–79 | 56 | 30 | (54) | 656 | 167 | (26) | < 0.001 | 3.38 | (1.94–5.88) | 24 | 14 | (58) | 810 | 252 | (31) | 0.007 | 3.10 | (1.36–7.07) |
≥ 80 | 35 | 19 | (54) | 139 | 36 | (16) | < 0.001 | 6.08 | (2.61–14.13) | 31 | 9 | (29) | 179 | 63 | (35) | 0.546 | 0.75 | (0.33–1.73) |
Diabetes | 130 | 54 | (42) | 2694 | 360 | (13) | < 0.001 | 4.61 | (3.19–6.64) | 87 | 27 | (31) | 3169 | 285 | (9) | < 0.001 | 4.55 | (2.85–7.29) |
18–49 | 9 | 1 | (11) | 1094 | 34 | (3) | 0.253 | 3.90 | (0.47–32.04) | 8 | 1 | (13) | 1254 | 32 | (3) | 0.191 | 5.46 | (0.65–45.65) |
50–64 | 20 | 9 | (45) | 831 | 131 | (16) | 0.002 | 4.37 | (1.78–10.76) | 13 | 4 | (31) | 921 | 76 | (8) | 0.020 | 4.94 | (1.49–16.42) |
65–79 | 58 | 29 | (50) | 661 | 171 | (26) | < 0.001 | 2.87 | (1.66–4.93) | 25 | 10 | (40) | 811 | 143 | (18) | 0.014 | 3.11 | (1.37–7.07) |
≥ 80 | 43 | 15 | (35) | 108 | 24 | (22) | 0.148 | 1.88 | (0.87–4.07) | 41 | 12 | (29) | 183 | 34 | (19) | 0.137 | 1.81 | (0.84–3.93) |
Coronary artery disease | 130 | 35 | (27) | 1936 | 230 | (12) | < 0.001 | 2.73 | (1.81–4.12) | 87 | 18 | (21) | 2301 | 179 | (8) | < 0.001 | 3.09 | (1.80–5.31) |
18–49 | 9 | 2 | (22) | 61 | 0 | (0) | 0.015 | – | 8 | 0 | (0) | 81 | 1 | (1) | 1.000 | – | ||
50–64 | 20 | 0 | (0) | 956 | 64 | (7) | 0.636 | – | 13 | 0 | (0) | 1025 | 30 | (3) | 1.000 | – | ||
65–79 | 58 | 15 | (26) | 775 | 126 | (16) | 0.069 | 1.80 | (0.97–3.33) | 25 | 4 | (16) | 940 | 81 | (9) | 0.268 | 2.02 | (0.67–6.03) |
≥ 80 | 43 | 18 | (42) | 144 | 40 | (28) | 0.092 | 1.87 | (0.92–3.80) | 41 | 14 | (34) | 255 | 67 | (26) | 0.345 | 1.46 | (0.72–2.94) |