Table 4 Distribution of Penicillin G-, Erythromycin-, Cotrimoxazole-, Tetracycline-, Chloramphenicol- Ceftriaxone– non susceptible (I + R) strains among adult and elderly patients during pre- and post-vaccination periods
Antibiotic | Adult (15–59 years old) | Elderly (≥ 60 years old) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Pre-vaccine period 2007–2010a | Post-vaccine period (2011–2019) | p-value | Pre-vaccine period | Post-vaccine period (2011–2019)b | p-value | |||||
2007–2010 (N = 71) | Early post period:2011–2014 (N = 57) | Mature post period: 2015–2019 (N = 69) | (2011–2014) | (2015–2019) | 2007–2010 (N = 15) | Early post-vaccine period: 2011–2014 (N = 26) | Mature post-vaccine period: 2015–2019 (N = 12) | (2011–2014) | (2015–2019) | |
Penicillin G n (%) | 17 (23.94) | 5 (8.77) | 11 (15.94) | 0.02 | 0.23 | 2 (13.33) | 2 (7.69) | 2 (16.66) | 0.61 | 0.81 |
Erythromycin n (%) | 5 (7.04) | 6 (10.52) | 11 (15.94) | 0.48 | 0.09 | 1 (6.66) | 2 (7.69) | 1 (8.33) | 1 | 0.87 |
Cotrimoxazole n (%) | 21 (29.58) | 5 (8.77) | 5 (7.24) | 0.003 | 0.0007 | 2 (13.33) | 2 (7.69) | 0 (0.00) | 0.61 | 0.19 |
Tetracycline n (%) | 22 (30.98) | 11 (19.30) | 23 (33.33) | 0.13 | 0.76 | 4 (26.27) | 6 (23.08) | 3 (25.00) | 0.9 | 0.94 |
Chloramphenicol n (%) | 3 (4.22) | 6 (10.53) | 3 (4.34) | 0.29 | 0.96 | 3 (20.00) | 1 (3.85) | 1 (8.33) | 0.13 | 0.4 |
Ceftriaxone n (%) | 1 (1.41) | 1 (1.75) | 2 (2.89) | 1 | 0.54 | 0 (0.00) | 0 (0.00) | 0 (0.00) | NS | NS |