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Table 4 The Association between Post-vaccination Side effects Reported by the Participants for the second shot and their predisposing factors (N = 1027)

From: Side effects of Pfizer/BioNTech (BNT162b2) COVID-19 vaccine reported by the Birzeit University community

Post-vaccination adverse events

Predisposing factors (p-value*)

Gender

Age

Chronic diseases

BMI

Allergy

Anaphylaxis shock

Smoking

Pre-vaccination COVID-19 infection

No symptoms

< 0.001

0.382

0.438

0.328

0.279

0.740

0.032

0.149

Local adverse events

 Pain and swelling at the injection site

0.002

0.852

0.993

0.545

0.007

0.937

0.641

0.144

 Swollen armpit glands

0.465

0.458

0.270

0.118

0.256

0.185

0.965

0.771

Systemic adverse events

 Fever

0.003

0.618

0.145

0.379

0.010

0.086

0.472

0.092

 Chills

< 0.001

0.301

0.018

0.083

0.013

0.686

0.860

0.076

 Headache

< 0.001

0.527

0.035

0.868

0.003

0.196

0.248

0.717

 Increase in Blood pressure

0.020

0.683

0.363

0.653

0.035

0.04

0.782

0.106

 Increase in heart rate

0.002

0.443

0.003

0.811

0.039

0.02

0.408

0.512

 Shortness of breath

< 0.001

0.358

< 0.001

0.144

< 0.001

< 0.001

0.712

0.024

 Persistent cough

0.098

0.012

0.691

0.367

< 0.001

0.048

0.261

0.029

 Chest pain

0.002

0.553

0.247

0.344

0.005

0.099

0.854

0.025

 Voice hoarseness

< 0.001

0.059

1.000

0.107

0.044

0.121

1.000

0.581

 Dizziness

0.005

0.398

0.028

0.443

< 0.001

0.002

0.540

0.555

 Ringing in the ears (tinnitus)

0.026

0.488

0.536

0.528

< 0.001

< 0.001

0.065

0.264

 Nausea

0.058

0.826

0.226

0.895

< 0.001

0.007

0.976

0.657

 Vomiting

0.497

0.885

0.562

0.602

< 0.001

0.001

0.100

0.681

 Diarrhea

0.401

0.559

0.038

0.017

< 0.001

0.001

0.018

0.028

 Abdominal pain

0.053

0.673

0.613

0.390

< 0.001

0.004

0.831

0.007

 Tiredness and fatigue

< 0.001

0.175

0.954

0.393

0.093

0.284

0.276

0.402

 Myalgia (muscle pain)

< 0.001

0.672

0.115

0.122

0.025

0.205

0.709

0.164

 Joint pain

< 0.001

0.276

0.154

0.277

0.079

0.026

0.837

0.564

 Swollen ankles and feet

0.631

0.771

0.351

0.089

0.002

0.007

0.032

0.138

 Sleep disturbances

0.002

0.610

0.008

0.117

0.001

0.026

0.505

0.891

 Menstrual cycles changes

0.014

 

0.977

0.001

0.094

0.427

0.137

  1. Chi-square test*