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Table 3 In-hospital mortality rate (%) in adult hospitalized Covid-19 patients according to some personal characteristics, comorbidities and laboratory findings

From: Clinical characteristics and outcome of Covid-19 illness and predictors of in-hospital mortality in Saudi Arabia

 

Inhospital mortality

No (%)

cOR (95% CI)

P value

aOR (95% CI)

P-value

A. Personal characteristics

Gender

     

 Female

276 (7.5)

1

 

1

 

 Male

462 (13.7)

1.95 (1.67–2.28)

< 0.001*

1.05 (0.75–1.48)

0.76

Age (years)

     

 < 30

10 (1.2)

1

 

1

 

 30–

59 (3.1)

2.51 (1.28–4.93)*

0.006*

1.40 (0.37–5.23)

0.62

 50–

306 (11.4)

10.24 (5.43–19.32)*

< 0.001*

3.15 (0.89–11.14)

0.08

 70 or more

363 (22.5)

23.07 (12.23–43.51)*

< 0.001*

6.93 (1.94–24.79)

0.003*

BMI (kg/m2)

     

 < 25

166 (17.6)

1

 

1

 

 25–

213 (15.3)

0.85 (0.68–1.06)

0.14

1.22 (0.78–1.90)

0.40

 30 or more

302 (12.4)

0.66 (0.54–0.82)*

0.001*

1.25 (0.81–1.94)

0.31

B. Comorbidities

Diabetes

     

 No

493 (9.7)

1

 

1

 

 Yes

245 (12.4)

1.32 (1.12–1.55)*

0.001

1.04 (0.71–1.52)

0.85

Hypertension

     

 No

510 (9.5)

1

 

1

 

 Yes

228 (13.9

1.54 (1.30–1.82)*

< 0.001

0.78 (0.52–1.16)

0.22

Ischemic heart disease

     

 No

669 (10.1)

1

 

1

 

 Yes

69 (17.5)

1.89 (1.44–2.48)*

< 0.001

1.80 (1.05–3.09)*

0.034*

Cancer

     

 No

677 (10.3)

1

 

1

 

 Yes

61 (13.8)

1.40 (1.06–1.86)*

0.018*

1.73 (0.99–3.02)

0.053

COPD

     

 No

726 (10.4)

1

 

1

 

 Yes

12 (21.8)

2.40 (1.26–4.58)*

0.006*

0.60 (0.19–1.90)

0.38

Asthma

     

 No

720 (10.5)

1

 

1

 

 Yes

18 (9.0)

0.84 (0.52–1.38)

0.50

1.41(0.60–3.37)

0.44

ICU adm

     

 No

165 (3.0)

1

 

1

 

 Yes

573 (38.7)

20.58 (17.08–24.81)*

< 0.001*

24.38 (15.64–38.01)*

< 0.001*

C. Laboratory findings

CRP

     

 Normal

43 (4.6)

1

 

1

 

 Abnormal

549 (14.9)

3.62 (2.63–4.98)*

< 0.001*

1.85 (1.08–3.16)*

0.024*

d-Dimer

     

 Normal

36 (2.7)

1

 

1

 

 Abnormal

583 (16.2)

7.06 (5.01–9.95)*

< 0.001*

1.96 (1.15–3.36)*

0.014*

Ferritin

     

 Normal

87 (5.1)

1

 

1

 

 Abnormal

564 (15.9)

3.50 (2.77–4.42)*

< 0.001*

1.40 (0.91–2.16)

0.13

LDH

     

 Normal

13 (1.7)

1

 

1

 

 Abnormal

656 (1`4.7)

9.97 (5.73–17.36)*

< 0.001*

2.56 (0.82–7.98)

0.10

Lymphocytes

     

 Normal

267 (6.3)

1

 

1

 

 Decreased

400 (21.5)

4.06 (3.44–4.79)*

< 0.001*

2.76 (2.03–3.3.76)*

< 0.001*

 Increased

4 (7.5)

1.21 (0.43–3.38)

 

0.000

0.99

Neutrophils

     

 Normal

279 (7.0)

1

 

1

 

 Increased

368 (25.3)

4.49 (3.79–5.32)*

< 0.001*

2.10 (1.54–2.87)*

< 0.001*

 Decreased

28 (4.0)

0.55 (0.37–0.82)

 

1.04 (0.45–2.41)

0.93

Procalcitinon

     

 Normal

32 (3.5)

1

 

1

 

 Abnormal

564 (18.7)

6.30 (4.38–9.08)*

< 0.001*

3.33 (1.88–5.90)*

< 0.001*

  1. cOR: crude odds ratio; aOR: adjusted odds ratio; *Statistically significant, LDH: Lactate Dehydrogenase, CRP: c-reactive protein; COPD: chronic obstructive pulmonary disease