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Table 4 Comparison of characteristics and hematologic and inflammatory parameters between Groups I + II + III and IV

From: Hematologic and inflammatory parameters for determining severity of odontogenic infections at admission: a retrospective study

Group

I + II + III (n = 258)

IV (n = 13)

P value

Age (years)

61 [41, 74]

73 [41, 75]

0.298

Sex (male)

133 (51.6%)

5 (38.5%)

0.405

Body mass index

22.4 [20.2, 25.0]

21.3 [18.7, 23.4]

0.345

Cause

  

0.672

Lesion

  

0.571

 Maxilla

53 (20.5%)

1 (7.7%)

 

 Mandible

200 (77.5%)

12 (92.3%)

 

 Others†

5 (1.9%)

0

 

Location of odontogenic cause

  

0.565

 Anterior

32 (12.4%)

1 (7.7%)

 

 Premolar

20 (7.8%)

0

 

 Molar

180 (69.8%)

12 (92.3%)

 

 Others‡

26 (10.1%)

0

 

Compromised host§

63 (24.4%)

7 (53.8%)

0.044*

Fever (°C)

37.2 [36.6, 37.7]

37.4 [36.9, 37.8]

0.207

Blood test data

   

 Albumin (g/dl)

3.6 [3.3, 4.0]

2.7 [2.4, 3.0]

 < 0.001*

 C-reactive protein (mg/dl)

9.1 [5.7, 13.9]

23.9 [21.0, 32.3]

 < 0.001*

 White blood cell (× 103/µl)

12.1 [9.7, 14.7]

19.0 [14.7, 21.0]

 < 0.001*

 Neutrophil (%)

80.8 [74.7, 85.4]

91.5 [89.4, 93.4]

 < 0.001*

 Lymphocyte (%)

12.0 [8.1, 17.0]

3.9 [2.4, 6.0]

 < 0.001*

Platelet (× 104/µl)

26.2 [21.1, 31.5]

33.1 [18.0, 36.6]

0.382

Hemoglobin (g/dl)

13.4 [12.3, 14.6]

11.9 [10.7, 13.1]

0.027*

Sodium (mmol/L)

139 [137, 140]

136 [133, 140]

0.064

Creatinine (mg/dl)

0.76 [0.62, 0.94]

0.98 [0.77, 1.59]

0.035*

Glucose (mg/dl)

115 [100, 133]

112 [96, 138]

0.988

LRINEC score

1 [1, 4]

7 [6, 8]

 < 0.001*

NLR

6.7 [4.4, 10.3]

23.3 [15.3, 38.9]

 < 0.001*

PLR

179.8 [134.3, 265.3]

301.9 [235.5, 662.4]

0.006*

SII

173.7 [110.2, 292.3]

706.3 [494.7, 925.7]

 < 0.001*

CRP + NLR

16.3 [12.0, 23.8]

51.0 [35.1, 60.8]

 < 0.001*

  1. Data are shown as the median [first quartile, third quartile]
  2. *Statistically significant (P < 0.05)
  3. LRINEC laboratory risk indicator for necrotizing fasciitis, NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; SII, systemic immune-inflammation index
  4. †Buccal; tongue
  5. ‡Maxillary sinus; salivary gland; lip
  6. §Diabetes mellitus; corticosteroids usage; hemodialysis