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Table 2 Comparison of hematologic and inflammatory markers among groups

From: Hematologic and inflammatory parameters for determining severity of odontogenic infections at admission: a retrospective study

 

Group

P valuea

Trend testb

I (n = 123)

II (n = 64)

III (n = 71)

IV (n = 13)

P value

Blood test data

      

 Albumin (g/dl)

3.8 [3.3, 4.2]

4.1 [3.6, 4.1]

3.4 [3.1, 3.7]

2.7 [2.4, 3.0]

 < 0.001*

 < 0.001*

 C-reactive protein (mg/dl)

7.5 [4.4, 10.3]

9.2 [6.1, 13.1]

15.3 [10.1, 19.0]

23.9 [21.0, 32.3]

 < 0.001*

 < 0.001*

 White blood cell (× 103/µl)

10.8 [9.1, 13.3]

12.2 [9.9, 15.7]

14.3 [11.8, 16.6]

19.0 [14.7, 21.0]

 < 0.001*

 < 0.001*

  Neutrophil (%)

77.1 [72.0, 82.1]

80.5 [74.5, 83.1]

86.5 [83.1, 88.2]

91.5 [89.4, 93.4]

 < 0.001*

 < 0.001*

  Lymphocyte (%)

14.7 [11.1, 19.2]

12.7 [9.6, 16.8]

7.1 [5.0, 10.2]

3.9 [2.4, 6.0]

 < 0.001*

 < 0.001*

 Platelet (× 104/µl)

24.6 [20.7, 29.7]

25.7 [19.7, 31.4]

29.1 [22.9, 37.5]

33.1 [18.0, 36.6]

0.001*

 < 0.001*

 Hemoglobin (g/dl)

13.8 [12.3, 14.7]

13.4 [12.7, 15.1]

12.9 [11.6, 14.2]

11.9 [10.7, 13.1]

0.004*

0.004*

 Sodium (mmol/L)

139 [137, 140]

138 [137, 140]

139 [137, 140]

136 [133, 140]

0.059

0.073

 Creatinine (mg/dl)

0.75 [0.62, 0.92]

0.76 [0.62, 0.92]

0.74 [0.62, 1.01]

0.98 [0.77, 1.59]

0.091

0.188

 Glucose (mg/dl)

110 [99, 120]

121 [100, 148]

116 [105, 132]

112 [96, 138]

0.083

0.073

LRINEC score

1 [0, 1]

1 [1, 2]

4 [1, 5]

7 [6, 8]

 < 0.001*

 < 0.001*

NLR

5.2 [3.8, 7.4]

6.3 [4.7, 8.6]

12.1 [8.0, 17.5]

23.3 [15.3, 38.9]

 < 0.001*

 < 0.001*

PLR

156.2 [126.8, 193.2]

166.5 [128.7, 232.3]

319.0 [224.4, 394.1]

301.9 [235.5, 662.4]

 < 0.001*

 < 0.001*

SII

134.4 [93.0, 177.4]

164.1 [107.9, 228.8]

349.1 [239.6, 533.3]

706.3 [494.7, 925.7]

 < 0.001*

 < 0.001*

CRP + NLR

13.4 [9.5, 16.6]

16.3 [12.5, 22.1]

27.8 [21.0, 35.2]

51.0 [35.1, 60.8]

 < 0.001*

 < 0.001*

  1. Data are shown as the median [first quartile, third quartile]
  2. *Statistically significant (P < 0.05)
  3. aKruskal − Wallis test; bJonckheere − Terpstra test
  4. LRINEC laboratory risk indicator for necrotizing fasciitis, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, SII systemic immune-inflammation index