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Table 4 Nucleotide diversity and tests of neutrality of the pvs28 gene in P. vivax isolates from three sites in China, 2009–2020

From: Genetic diversity of transmission-blocking vaccine candidate antigens Pvs25 and Pvs28 in Plasmodium vivax isolates from China

Sites

No. of isolates

S

H

Hd ± SD

K

π ± SD

Tajima’s D (P value)

dN

dS

Nyingchi

5

4

3

0.800 ± 0.164

2.400

0.00417 ± 0.00101

1.64070 (P > 0.10)

2.40000

0.00000

Tengchong

206

10

21

0.841 ± 0.008

1.671

0.00966 ± 0.00031

0.86672 (P > 0.10)

2.97016

0.91120

Yingjiang

45

7

5

0.470 ± 0.081

1.513

0.00263 ± 0.00051

− 0.48164 (P > 0.10)

1.46869

0.04444

Total

256

11

22

0.485 ± 0.087

1.679

0.00305 ± 0.00061

− 0.52637 (P > 0.10)

2.73584

0.72924

  1. S number of polymorphic sites, H number of haplotypes, Hd haplotype diversity, K average number of nucleotide differences, π nucleotide diversity, dN number of non-synonymous substitutions, dS number of synonymous substitutions
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BMC Infectious Diseases

ISSN: 1471-2334

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