Skip to main content

Table 2 Amino acid variation of the Pvs28 in P. vivax isolates from China, 2009–2020

From: Genetic diversity of transmission-blocking vaccine candidate antigens Pvs25 and Pvs28 in Plasmodium vivax isolates from China

Haplotypes

Number (%)

EGF-1

EGF-2

EGF-3

GSGGE/D repeats

52

53

65

81

95

98

105

116

125

131

140

Sal-I

M

A

T

A

G

L

E

L

D

S

T

6

WT

8 (2.9)

           

6–7

H1

5 (1.8)

L

          

5–7

H2

2 (0.7)

 

V

         

6–8

H3

3 (1.1)

    

N

      

6

H4

7 (2.6)

      

K

    

5–6

H5

15 (5.5)

       

V

   

6

H6

1 (0.3)

         

N

 

6

H7

13 (4.8)

          

S

5–7

H8

1 (0.3)

L

      

V

   

6

H9

79 (29.0)

L

         

S

5–7

H10

10 (3.7)

 

V

     

V

   

6

H11

16 (5.9)

 

V

        

S

6–7

H12

1 (0.3)

    

N

 

K

    

6

H13

13 (4.8)

     

I

 

V

   

6

H14

51 (18.8)

      

K

V

   

5–7

H15

1 (0.3)

L

    

I

 

V

   

6

H16

1 (0.3)

L

V

        

S

6

H17

11 (4.0)

L

 

K

       

S

4–6

H18

6 (2.2)

L

    

S

    

S

6

H19

1 (0.3)

L

       

N

 

S

6

H20

7 (2.6)

 

V

 

T

   

V

   

6–7

H21

2 (0.7)

     

I

 

V

  

S

6

H22

18 (6.6)

L

 

K

V

      

S

5–6

Total

272 (100)

  1. EGF, epidermal growth factor-like domain. Dot (•) indicates identical amino acid residues compared to the Sal-I strain. Bold letters indicate amino acid variation compared to the Sal-I strain