Recovered (R) | Affected (A) | CHIK- (NC) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
(n = 107) | (n = 62) | (n = 151) | Difference | Difference | |||||||
Median (IQR) | Mean (SD) | Median (IQR) | Mean (SD) | Median (IQR) | Mean (SD) | P-valuea | (R – NC) | P-valueb | (A – NC) | P-valueb | |
Physical functioning | 90.0 (60.0–100) | 80.4 (26.0) | 65.0 (43.8–90.0) | 65.6 (28.4) | 95.0 (80.0–100) | 85.9 (27.0) | < .001 | 5.0 | .27 | − 30.0 | < .001 |
Social functioning | 100 (87.5–100) | 90.2 (16.4) | 87.5 (75.0–100) | 84.5 (17.8) | 100 (87.5–100) | 92.6 (16.3) | < .001 | 0.0 | .11 | − 12.5 | < .001 |
Physical role functioning | 100 (100–100) | 81.3 (36.0) | 100 (0.0–100) | 64.5 (44.0) | 100 (100–100) | 90.1 (27.9) | < .001 | 0.0 | .03 | 0.0 | < .001 |
Emotional health perception | 100 (100–100) | 89.7 (29.1) | 100 (100–100) | 83.3 (33.5) | 100 (100–100) | 94.1 (21.8) | .01 | 0.0 | .24 | 0.0 | .003 |
Mental health | 92.0 (76.0–100) | 85.5 (15.6) | 84.0 (67.0–92.0) | 79.5 (17.5) | 92.0 (84.0–100) | 87.6 (15.0) | .003 | 0.0 | .46 | − 8.0 | < .001 |
Vitality | 85.0 (65.0–95.0) | 79.7 (17.3) | 70.0 (55.0–85.0) | 67.3 (20.5) | 85.0 (75.0–95.0) | 82.1 (15.1) | < .001 | 0.0 | .39 | − 15.0 | < .001 |
Bodily pain | 89.8 (67.4–100) | 84.7 (19.7) | 67.4 (48.5–79.6) | 65.7 (20.6) | 100 (79.6–100) | 88.5 (18.4) | < .001 | -10.2 | .05 | − 32.6 | < .001 |
General health perception | 75.0 (60.0–85.0) | 71.7 (16.7) | 55.0 (48.8–75.0) | 58.3 (19.3) | 75.0 (65.0–80.0) | 74.4 (12.6) | < .001 | 0.0 | .38 | − 20.0 | < .001 |
PCSc | 87.4 (73.1–93.8) | 79.5 (20.5) | 66.2 (45.4–84.0) | 63.5 (23.7) | 91.3 (82.4–95.0) | 84.7 (17.1) | < .001 | -3.9 | .05 | − 25.1 | < .001 |
Gender | |||||||||||
Female | 89.7 (79.0–95.0) | 82.4 (18.6) | 64.0 (39.7–84.3) | 61.3 (24.4) | 88.8 (80.9–95.0) | 84.2 (17.7) | < .001 | 0.9 | .83 | − 24.8 | < .001 |
Male | 83.8 (50.6–91.2) | 73.2 (23.3) | 80.9 (61.2–85.2) | 75.1 (15.5) | 92.5 (86.7–95.0) | 85.7 (16.1) | < .001 | -8.7 | .002 | -11.6 | .004 |
Age, years | |||||||||||
23–29 | 96.3 (96.3–96.3) | 96.3 (0.0) | 81.5 (80.6–81.5) | 81.5 (1.3) | 92.5 (88.6–95.3) | 92.7 (3.7) | .04 | 3.8 | .18 | − 11.0 | .03 |
30–44 | 93.8 (82.5–95.9) | 88.1 (12.4) | 63.7 (46.8–82.4) | 63.1 (20.5) | 91.3 (86.8–96.3) | 85.9 (18.1) | .001 | 2.5 | .84 | − 27.6 | .001 |
45–59 | 89.3 (80.0–95.0) | 84.3 (15.7) | 77.1 (55.5–89.6) | 70.1 (21.4) | 91.9 (86.2–95.0) | 89.2 (12.5) | < .001 | − 2.6 | .26 | − 14.8 | < .001 |
≥ 60 | 81.8 (47.8–91.2) | 69.8 (24.3) | 50.5 (29.0–78.4) | 53.3 (26.0) | 88.8 (77.7–93.8) | 81.5 (18.9) | < .001 | -7.0 | .004 | -38.3 | < .001 |
Comorbidities | |||||||||||
Rheumatic disordersd | 80.6 (44.0–89.2) | 68.7 (24.7) | 55.5 (31.9–66.5) | 52.7 (19.7) | 84.9 (59.3–88.6) | 71.8 (23.9) | .01 | − 4.3 | .76 | − 29.4 | .006 |
Cardiovascular diseasese | 82.4 (47.8–92.5) | 73.1 (24.2) | 63.1 (29.3–83.7) | 58.0 (26.7) | 82.4 (72.4–91.3) | 76.0 (20.6) | .01 | 0.0 | .94 | − 19.3 | .007 |
Diabetes mellitus | 59.3 (37.8–90.3) | 60.2 (27.9) | 73.7 (23.2–85.6) | 58.1 (31.4) | 76.3 (62.1–88.7) | 72.0 (22.4) | .43 | − 17.0 | .30 | − 2.6 | .29 |
Asthma | 91.2 (75.9–96.3) | 85.9 (12.4) | 35.0 (26.2–77.1) | 48.5 (25.1) | 81.2 (34.4–92.5) | 69.4 (33.1) | .02 | 10.0 | .33 | − 46.2 | .33 |
Allergiesf | 92.4 (58.4–95.0) | 78.5 (25.8) | 79.0 (51.8–84.3) | 69.5 (21.8) | 92.5 (85.5–93.8) | 85.5 (16.8) | .05 | − 0.1 | .71 | − 13.5 | .01 |
MCSg | 92.1 (81.0–97.5) | 86.5 (15.5) | 85.7 (70.6–92.0) | 78.6 (18.3) | 93.3 (86.8–97.5) | 89.1 (13.7) | < .001 | − 1.2 | .20 | − 7.6 | < .001 |
Gender | |||||||||||
Female | 92.1 (81.4–98.8) | 87.3 (14.3) | 84.2 (65.3–90.3) | 76.2 (18.7) | 93.0 (86.3–96.4) | 88.1 (14.6) | < .001 | − 0.9 | .99 | − 8.8 | < .001 |
Male | 90.6 (78.7–96.5) | 84.0 (18.0) | 92.5 (89.9–96.6) | 91.2 (7.7) | 95.1 (88.5–98.8) | 90.9 (11.9) | .07 | − 4.5 | .02 | − 2.6 | .41 |
Age, years | |||||||||||
18–29 | 99.5 (99.0–99.5) | 99.5 (0.7) | 88.6 (86.0–88.6) | 88.6 (3.7) | 90.9 (87.1–94.2) | 89.6 (8.5) | .12 | 8.6 | .06 | − 2.3 | .49 |
30–44 | 93.7 (85.0–99.7) | 88.9 (13.6) | 75.3 (64.4–87.0) | 72.3 (20.0) | 86.5 (73.4–90.3) | 80.0 (18.9) | .01 | 7.2 | .05 | -11.2 | .16 |
45–59 | 91.6 (82.5–97.5) | 88.8 (11.3) | 89.9 (72.1–94.0) | 80.9 (19.1) | 94.8 (90.9–98.8) | 93.1 (8.0) | .003 | − 3.2 | .10 | − 4.9 | < .001 |
≥ 60 | 89.1 (75.7–96.6) | 81.8 (19.2) | 85.1 (66.4–90.2) | 78.0 (16.9) | 94.0 (86.8–97.3) | 89.3 (14.2) | < .001 | − 4.9 | .03 | − 8.9 | < .001 |
Comorbidities | |||||||||||
Rheumatic disordersd | 89.3 (78.3–97.6) | 83.3 (18.0) | 82.5 (57.4–86.6) | 73.6 (18.1) | 90.5 (71.3–95.0) | 81.8 (18.2) | .05 | − 1.2 | .56 | -8.0 | .08 |
Cardiovascular diseasese | 90.8 (77.6–98.1) | 83.3 (18.7) | 84.3 (69.4–90.8) | 78.7 (15.4) | 90.9 (85.1–94.1) | 85.5 (15.9) | .06 | -0.1 | .93 | -6.6 | .01 |
Diabetes mellitus | 81.6 (70.2–89.6) | 76.5 (20.6) | 89.1 (83.0–96.3) | 84.2 (19.2) | 92.8 (81.9–97.9) | 85.1 (19.5) | .14 | − 11.2 | .07 | − 3.7 | .54 |
Asthma | 94.0 (88.0–100) | 93.2 (6.8) | 82.5 (58.8–87.4) | 75.0 (16.0) | 88.4 (43.1–92.4) | 74.6 (30.9) | .01 | 5.6 | .11 | − 5.9 | .50 |
Allergiesf | 88.6 (64.7–98.8) | 82.8 (18.2) | 86.5 (74.4–92.3) | 84.6 (10.5) | 93.0 (70.9–95.3) | 83.5 (19.7) | .87 | − 4.4 | .95 | − 6.5 | .48 |