Table 2 Antimicrobial resistance pattern of predominant gram-negative bacilli (E. coli and K. pneumoniae only) among pregnant and nonpregnant females
Antibiotics | Pregnant GNB* n = 51 (6.2%) | Nonpregnant GNB* n = 86 (8.7%) | p-value | Odd ratio (95% confidence interval) |
|---|---|---|---|---|
Ampicillin | 31 (60.8%) | 60 (69.8%) | **0.03 | 2.49 (1.09, 5.66) |
Ticarcillin | 31(60.8%) | 56 (65.1%) | 0.06 | 2.15 (0.97, 4.76) |
Cefixime | 18 (35.3%) | 47 (54.7%) | **0.01 | 3.34 (1.57, 7.11) |
Cefoxitin | 8 (15.7%) | 27 (31.4%) | **0.02 | 3.21 (1.18, 8.74) |
Ceftazidime | 12 (23.5%) | 35 (40.7%) | **0.02 | 2.81 (1.21, 6.53) |
Ceftriaxone | 15 (29.4%) | 44 (51.2%) | **0.01 | 2.86 (1.26, 6.51) |
Co-trimoxazole | 17 (33.3%) | 41 (47.7%) | 0.07 | 2.95 (0.91, 9.63) |
Ciprofloxacin | 28 (54.9%) | 46 (53.5%) | 0.52 | 1.38 (0.52, 3.65) |
Ofloxacin | 18 (35.3%) | 32 (37.2%) | 0.84 | 0.9 (0.31, 2.61) |
Gentamicin | 8 (15.7%) | 12 (14.0%) | 0.92 | 0.95 (0.32, 2.83) |
Amikacin | 1 (2.0%) | 7 (8.1%) | 0.15 | 4.73 (0.56, 39.63) |
Amoxicillin-clavulanic acid | 16 (31.4%) | 38 (44.2%) | **0.01 | 4.65 (1.39, 15.58) |
Piperacillin-Tazobactam | 15 (29.4%) | 23 (26.7%) | 0.76 | 1.18 (0.41, 3.43) |
#Fosfomycin | 0 (0.0%) | 0 (0.0%) | – | – |
Nitrofurantoin | 15 (29.4%) | 23 (26.7%) | 0.97 | 0.98 (0.45, 2.14) |
Ertapenem | 3 (5.9%) | 2 (2.3%) | 0.38 | 0.44 (0.07, 2.76) |