Table 4 Clinical presentation in patients with COVID-19 during the five consecutive waves of the disease

Fever

15484, 33.5 (32.7–34.2)

6361, 38.1 (36.9–39.2)

19302, 33.8 (33.1–34.3)

25139, 34.2 (33.6–34.7)

44329, 32.9 (32.4–33.3)

Cough

22252, 48.1 (47.4–48.7)

7606, 45.5 (44.3–46.6)

28933, 50.6 (50.0–51.1)

40894, 55.6 (55.1–56.0)

81404, 60.4 (60.0–60.7)

Muscle ache

11214, 24.2 (23.4–24.9)

5633, 33.7 (32.4–34.9)

21470, 37.6 (36.9–38.2)

27287, 37.1 (36.5–37.6)

59508, 44.2 (43.8–44.5)

Difficulty breathing

16600, 35.9 (35.1–36.6)

7579, 45.3 (44.1–46.4)

29419, 51.5 (50.9–52.7)

34871, 47.4 (46.8–47.9)

44290, 32.9 (32.4–33.3)

Chest pain

31, 0.1 (0.0–4.5)

536, 3.2 (1.7–4.6)

2339, 4.1 (3.2–4.9)

2656, 3.6 (2.8–4.3)

3521, 2.6 (2.0–3.1)

Loss of smell

423, 0.9 (0.0–1.8)

449, 2.7 (1.2–4.1)

1738, 3.0 (2.1–3.8)

1915, 2.6 (1.8–3.3)

4693, 3.5 (2.9–4.0)

Loss of taste

172, 0.4 (0.0–1.3)

261, 1.6 (0.0–3.1)

1210, 2.1 (1.2–2.9)

964, 1.3 (0.5–2.0)

3144, 2.3 (1.7–2.8)

Loss of appetite

64, 0.1 (0.0–0.8)

1127, 6.7 (5.2–8.1)

4602, 8.1 (7.3–8.8)

7101, 9.7 (9.0–10.3)

13451, 10.1 (9.5–10.6)

Nausea

74, 0.2 (0.0–1.2)

1079, 6.5 (5.0–7.9)

4220, 7.4 (6.6–8.1)

4940, 6.7 (6.0–7.3)

9989, 7.4 (6.8–7.9)

Abdominal pain

26, 0.1 (0.0–1.3)

487, 2.9 (1.4–4.3)

1563, 2.7 (1.8–3.5)

1981, 2.7 (1.9–3.4)

3214, 2.4 (1.8–2.9)

Diarrhea

32, 0.1 (0.0–1.1)

798, 4.8 (3.3–6.2)

1932, 3.4 (2.5–4.2)

2132, 2.9 (2.1–3.6)

2846, 2.1 (1.5–2.6)

Headache

96, 0.2 (0.0–1.0)

1170, 7.0 (5.5–8.4)

5514, 9.6 (8.8–10.3)

7898, 10.7 (10.0–11.3)

17521, 13.0 (12.5–13.4)

Vertigo

20, 0.0 (0.0–0.0)

456, 2.7 (1.2–4.1)

1789, 3.1 (2.2–3.9)

2758, 3.7 (2.9–4.4)

4834, 3.6 (3.0–4.1)

Seizure

27, 0.1 (0.0–1.2)

42, 0.3 (0.0–1.9)

115, 0.2 (0.0–1.0)

97, 0.1 (0.0–0.7)

180, 0.1 (0.0–0.7)

Paraplegia

5, 0.0 (0.0–0.0)

23, 0.1 (0.0–1.3)

108, 0.2 (0.0–1.0)

96, 0.1 (0.0–0.7)

138, 0.1 (0.0–0.6)

Skin lesions

1, 0.0 (0.0–0.0)

17, 0.1 (0.0–1.6)

60, 0.1 (0.0–0.8)

50, 0.1 (0.0–0.9)

121, 0.1 (0.0–0.6)