Table 3 Distribution of underlying diseases in patients with COVID-19 during the five consecutive waves of the disease
Underlying diseases | Wave 1 | Wave 2 | Wave 3 | Wave 4 | Wave 5 | P value |
|---|---|---|---|---|---|---|
n, % (95% CI) | n, % (95% CI) | n, % (95% CI) | n, % (95% CI) | n, % (95% CI) | ||
Diabetes | 3021, 6.5 (5.6–7.3) | 1785, 10.7 (9.2–12.1) | 7460, 13.1 (12.3–13.8) | 8104, 11.0 (10.3–11.6) | 10615, 7.9 (7.3–8.4) |  < 0.001 |
Hypertension | 1476, 3.2 (2.3–4.0) | 2033, 12.2 (10.7–13.6) | 8666, 15.2 (14.4–15.9) | 9820, 13.4 (12.7–14.0) | 11298, 8.4 (7.8–8.9) |  < 0.001 |
Cardiovascular diseases | 3146, 6.8 (5.9–7.6) | 1591, 9.5 (8.0–10.9) | 6259, 11.0 (10.2–11.7) | 7286, 9.9 (9.2–10.5) | 9142, 6.8 (6.2–7.3) |  < 0.001 |
Cancer | 582, 1.3 (0.3–2.2) | 326, 2.0 (0.4–3.5) | 1060, 1.9 (1.0–2.7) | 1005, 1.4 (0.6–2.1) | 1397, 1.0 (0.4–1.5) |  < 0.001 |
Asthma | 518, 1.1 (0.2–1.9) | 207, 1.2 (0.2–2.6) | 786, 1.4 (0.5–2.2) | 771, 1.0 (0.2–1.7) | 875, 0.6 (0.0–1.1) |  < 0.001 |
Chronic liver diseases | 164, 0.4 (0.0–1.3) | 81, 0.5 (0.0–2.0) | 291, 0.5 (0.0–1.3) | 307, 0.4 (0.0–1.1) | 489, 0.4 (0.0–0.9) |  < 0.001 |
Chronic kidney diseases | 642, 1.4 (0.4–2.3) | 352, 2.1 (0.6–3.5) | 1194, 2.1 (1.2–2.9) | 974, 1.3 (0.5–2.0) | 1401, 1.0 (0.4–1.5) |  < 0.001 |
Chronic neurological diseases | 304, 0.7 (0.0 1.6) | 147, 0.9 (0.0–2.4) | 581, 1.0 (0.1- 1.8) | 454, 0.6 (0.0- 1.3) | 614, 0.5 (0.0- 1.0) |  < 0.001 |
Chronic immune deficiency diseases | 125, 0.3 (0.0–1.2) | 57, 0.3 (0.0–1.7) | 141, 0.2 (0.0–0.9) | 201, 0.3 (0.0–1.0) | 229, 0.2 (0.0- 0.7) |  < 0.001 |
Chronic hematological diseases | 160, 0.3 (0.0- 1.1) | 85, 0.5 (0.0–1.9) | 253, 0.4 (0.0–1.1) | 226, 0.3 (0.0–1.0) | 413, 0.3 (0.0–0.8) |  < 0.001 |
Positive history of smoking | 456, 1.0 (0.0–1.9) | 307, 1.8 (0.3–3.2) | 927, 1.6 (0.7–2.4) | 1091, 1.5 (0.7–2.2) | 1786, 1.3 (0.7–1.8) |  < 0.001 |
Positive history of opioids | 223, 0.5 (0.0–1.4) | 129, 0.8 (0.0–2.3) | 523, 0.9 (0.0–1.7) | 482, 0.7 (0.0–1.4) | 818, 0.6 (0.0–1.1) |  < 0.001 |