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Table 4 Detection of S. pneumoniae serotypes by real time PCR detection of in patients with or without radiological pneumonia and WHO/IMCI pneumonia

From: Pneumococcal concentration and serotype distribution in preschool children with radiologically confirmed pneumonia compared to healthy controls prior to introduction of pneumococcal vaccination in Zanzibar: an observational study

Serogroup/type, order of frequency

Patients with IMCI pneumoniaa

Patients without IMCI pneumoniaa

p-valueb

Patients with radiological pneumonia

Patients without radiological pneumonia

p-valueb

(n = 369)

(n = 216)

(n = 39)

(n = 292)

6A/B/C/D

68 (18%)

42 (19%)

0.827

6 (15%)

54 (18%)

0.825

19F

43 (12%)

38 (18%)

0.048

1 (3%)

37 (13%)

0.064

19A

21 (6%)

14 (6%)

0.720

3 (8%)

16 (5%)

0.478

14

28 (8%)

8 (4%)

0.074

6 (15%)

19 (7%)

0.097

23F

13 (4%)

11 (5%)

0.391

3 (8%)

9 (3%)

0.157

15BC

11 (3%)

11 (5%)

0.259

1 (3%)

10 (3%)

1.000

11

15 (4%)

8 (4%)

1.000

3 (8%)

9 (3%)

0.157

7C

9 (2%)

2 (1%)

0.344

0 (0%)

7 (2%)

1.000

5

6 (2%)

3 (1%)

1.000

0 (0%)

5 (2%)

1.000

10A

9 (2%)

1 (1%)

0.101

1 (3%)

7 (2%)

1.000

9A/V

6 (2%)

2 (1%)

0.717

3 (8%)

3 (1%)

0.024

18

2 (1%)

3 (1%)

0.364

0 (0%)

2 (1%)

1.000

12

3 (1%)

3 (1%)

0.675

0 (0%)

2 (1%)

1.000

3

3 (1%)

3 (1%)

0.675

0 (0%)

2 (1%)

1.000

4

2 (1%)

1 (0%)

1.000

1 (3%)

0 (0%)

0.118

  1. Serotypes positive in patients checked for radiological pneumonia: (Pneumococcus 20 (n = 4), 17 (n = 2), 22FA, 8, 4 (n = 1) 38, 33, 9 NL, 7FA, 2, 1 (n = 0)
  2. Serotypes positive in patients checked for IMCI pneumonia: Pneumococcus 20, (n = 4), 38, 22FA, 17, 1 (n = 2), 4 (n = 3), 9NL, 8, 2 (n = 1), 33, 7FA (n = 0)
  3. aAll tested for S. pneumoniae
  4. bFisher’s exact test, two-sided