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Table 5 The association of TCZ and SAR with DILI

From: Drug-induced liver injury following the use of tocilizumab or sarilumab in patients with coronavirus disease 2019

Drugs

N

ROR

PRR

IC

EBGM

  

(95% two-sided CI)

(χ2)

IC025

EBGM05

TCZ

191

1.33 (1.14, 1.55)

1.3 (13.27)

0.36 (0.31)

1.28 (1.13)

SAR

83

12.94 (9.6, 17.44)*

7.31 (468.91)*

2.83 (2.1)*

7.11 (5.54)*

  1. TCZ-associated DILI ROR=1.33, 95% two-sided CI(1.14,1.55), PRR=1.3, χ2=13.27, EBGM=1.28, 95% one-sided CI=1.2; SAR-associated DILI ROR=12.94, 95% two-sided CI(9.6,17.44), PRR=7.31, χ2=468.91, EBGM=7.11, 95% one-sided CI=5.54; * means a strong signal that represents a strong statistical association between the drug and the adverse reaction
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BMC Infectious Diseases

ISSN: 1471-2334

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