Initial empirical antibiotics of non-carbapenems for ESBL-producing E. coli and K. pneumoniae bacteremia in children: a retrospective medical record review

Table 3 Clinical Outcomes of the Study Population

Outcomes	Empirical antibiotics			P-value
Outcomes	Non-carbapenem^† (N = 26)	Carbapenem (N = 27)	Total (N = 53)	P-value
30-day all-cause mortality	1 (3.8%)	8 (29.6%)	9 (17.0%)	0.01
Microbiological failure on day 2	7 (26.9%)	11 (40.7%)	18 (34.0%)	0.29

^†In the non-carbapenem group, of in vitro susceptible appropriate empirical antibiotics (n = 6), there were no fatal cases and 3 cases with microbiological failure on day 2. In the non-carbapenem group, of in vitro resistant inappropriate empirical antibiotics (n = 20), there was one fatal case and 4 cases with microbiological failure on day 2

ISSN: 1471-2334