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Table 3 Full model results for a Cox regression predicting time to a registered positive test for individuals who had received an influenza vaccination within a year of the time period start date (as a proxy for healthcare engaged)

From: Changing patterns of SARS-CoV-2 infection through Delta and Omicron waves by vaccination status, previous infection and neighbourhood deprivation: a cohort analysis of 2.7 M people

 

Delta (3rd June–1st Sept 2021)

Delta (1st Sept–27th Nov 2021)

Omicron (13th Dec–2nd Feb 2022)

HR

LCI

UCI

HR

LCI

UCI

HR

LCI

UCI

Unvaccinated

Reference

  

Reference

  

Reference

  

Unadjusted

 1 dose

0.69

0.65

0.74

0.36

0.33

0.40

1.27

1.21

1.32

 2 doses

0.37

0.36

0.39

0.34

0.33

0.34

1.39

1.35

1.43

 3 doses

0.43

0.32

0.59

0.13

0.11

0.15

0.77

0.75

0.78

 Previous infection

0.19

0.17

0.22

0.14

0.13

0.16

0.58

0.56

0.60

 Deprivation Score

1.0061

1.0054

1.0067

0.9951

0.9946

0.9956

1.0009

1.0005

1.0013

Adjusted*

 1 dose

0.66

0.61

0.72

0.53

0.47

0.60

0.98

0.93

1.03

 2 doses

0.55

0.51

0.59

0.60

0.57

0.64

1.15

1.09

1.21

 3 doses

0.63

0.46

0.86

0.28

0.24

0.34

0.94

0.89

0.99

 Previous infection

0.17

0.15

0.19

0.11

0.10

0.13

0.45

0.44

0.47

 Deprivation Score

1.0031

1.0024

1.0038

0.9925

0.9920

0.9930

0.9992

0.9987

0.9996

  1. Definitions: HR = Hazard Ratio, LCI = 95% Lower Confidence Interval, UCI = 95% Upper Confidence Interval
  2. Deprivation score is numerical, with increasing values representing higher levels of deprivation
  3. *Adjusted for age (10-year age bands), sex, ethnicity, long-term illness, number of tests in previous month, time varying vaccination status (with an interaction to time), previous infection status (and interaction to time), and 2019 Index of Multiple Deprivation score